Role and interaction of p53, BAX and the stress-activated protein kinases p38 and JNK in benzo(a)pyrene-diolepoxide induced apoptosis in human colon carcinoma cells

Archives of Toxicology

Volumn 86, Issue 2, 2012, Pages 329-337

  Donauer, Julia ^a   Schreck, Ilona ^a   Liebel, Urban ^a   Weiss, Carsten ^a  

^a KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

Author keywords

Apoptosis; BAX; p53; Polycyclic aromatic hydrocarbons; Stress activated protein kinases

Indexed keywords

7,8 DIHYDROXYBENZO[A]PYRENE 9,10 OXIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; CANCER CELL; CELL DEATH; CELL LEVEL; COLON CARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; GENE ACTIVATION; GENE FUNCTION; GENE INTERACTION; GENE TARGETING; GENOTOXICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRANSCRIPTION REGULATION; WILD TYPE;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELLS, CULTURED; COLONIC NEOPLASMS; ENVIRONMENTAL POLLUTANTS; HCT116 CELLS; HUMANS; MAP KINASE KINASE 4; MUTAGENICITY TESTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; POLYCYCLIC HYDROCARBONS, AROMATIC; TUMOR SUPPRESSOR PROTEIN P53;

RODENTIA;

EID: 84856953019     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-011-0757-3     Document Type: Article

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