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Volumn 121, Issue 1, 2011, Pages 57-62

Sulforaphane-mediated reduction of aflatoxin B1-N7-guanine in rat liver DNA: Impacts of strain and sex

Author keywords

Aflatoxin B1; Chemoprevention; DNA adducts; Glutathione S Transferase; Liver cancer; Sulforaphane

Indexed keywords

AFLATOXIN B1; DNA; GLUTATHIONE TRANSFERASE; SULFORAPHANE;

EID: 79955410882     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr026     Document Type: Article
Times cited : (23)

References (28)
  • 1
    • 0000613334 scopus 로고
    • Aflatoxins
    • (C. D. Searle, Ed.). American Chemical Society, Washington, DC
    • Busby, W. F., and Wogan, G. N. (1984). Aflatoxins. In Chemical Carcinogens (C. D. Searle, Ed.), pp. 945-1136. American Chemical Society, Washington, DC.
    • (1984) Chemical Carcinogens , pp. 945-1136
    • Busby, W.F.1    Wogan, G.N.2
  • 3
    • 0029111905 scopus 로고
    • Levels of aflatoxin-albumin biomarkers in rat plasma are modulated by both long-term and transient interventions with oltipraz
    • Egner, P. A., Gange, S. J., Dolan, P. M., Groopman, J. D., Muñoz, A., and Kensler, T. W. (1995). Levels of aflatoxin-albumin biomarkers in rat plasma are modulated by both long-term and transient interventions with oltipraz. Carcinogenesis 16, 1769-1773.
    • (1995) Carcinogenesis , vol.16 , pp. 1769-1773
    • Egner, P.A.1    Gange, S.J.2    Dolan, P.M.3    Groopman, J.D.4    Muñoz, A.5    Kensler, T.W.6
  • 4
    • 33749005413 scopus 로고    scopus 로고
    • Quantification of aflatoxin-B1-N7-Guanine in human urine by high- performance liquid chromatography and isotope dilution tandem mass spectrometry
    • Egner, P. A., Groopman, J. D., Wang, J. S., Kensler, T. W., and Friesen, M. D. (2006). Quantification of aflatoxin-B1-N7-Guanine in human urine by high- performance liquid chromatography and isotope dilution tandem mass spectrometry. Chem. Res. Toxicol. 19, 1191-1195.
    • (2006) Chem. Res. Toxicol. , vol.19 , pp. 1191-1195
    • Egner, P.A.1    Groopman, J.D.2    Wang, J.S.3    Kensler, T.W.4    Friesen, M.D.5
  • 5
    • 0037188518 scopus 로고    scopus 로고
    • Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors
    • Fahey, J. W., Haristoy, X., Dolan, P. M., Kensler, T. W., Scholtus, I., Stephenson, K. K., Talalay, P., and Lozniewski, A. (2002). Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors. Proc. Natl. Acad. Sci. U.S.A 99, 7610-7615.
    • (2002) Proc. Natl. Acad. Sci. U. S. A , vol.99 , pp. 7610-7615
    • Fahey, J.W.1    Haristoy, X.2    Dolan, P.M.3    Kensler, T.W.4    Scholtus, I.5    Stephenson, K.K.6    Talalay, P.7    Lozniewski, A.8
  • 6
    • 0032841203 scopus 로고    scopus 로고
    • Antioxidant functions of sulforaphane: a potent inducer of phase II detoxication enzymes
    • Fahey, J. W., and Talalay, P. (1999). Antioxidant functions of sulforaphane: a potent inducer of phase II detoxication enzymes. Food Chem. Toxicol. 37, 973-979.
    • (1999) Food Chem. Toxicol. , vol.37 , pp. 973-979
    • Fahey, J.W.1    Talalay, P.2
  • 7
    • 0030931522 scopus 로고    scopus 로고
    • Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens
    • Fahey, J. W., Zhang, Y., and Talalay, P. (1997). Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proc. Natl. Acad. Sci. U.S.A 94, 10367-10372.
    • (1997) Proc. Natl. Acad. Sci. U. S. A , vol.94 , pp. 10367-10372
    • Fahey, J.W.1    Zhang, Y.2    Talalay, P.3
  • 8
    • 33747053966 scopus 로고    scopus 로고
    • Changes in hepatic cytosolic glutathione S-transferase activity and expression of its class-P during prenatal and postnatal period in rats treated with aflatoxin B1
    • Fatemi, F., Allameh, A., Dadkhah, A., Forouzandeh, M., Kazemnejad, S., and Sharifi, R. (2006). Changes in hepatic cytosolic glutathione S-transferase activity and expression of its class-P during prenatal and postnatal period in rats treated with aflatoxin B1. Arch. Toxicol. 80, 572-579.
    • (2006) Arch. Toxicol. , vol.80 , pp. 572-579
    • Fatemi, F.1    Allameh, A.2    Dadkhah, A.3    Forouzandeh, M.4    Kazemnejad, S.5    Sharifi, R.6
  • 9
    • 0019126444 scopus 로고
    • Nuclear distribution of aflatoxin B1 and its interaction with histones in rat liver in vivo
    • Groopman, J. D., Busby, W. F., and Wogan, G. N. (1980). Nuclear distribution of aflatoxin B1 and its interaction with histones in rat liver in vivo. Cancer Res. 40, 4343-4351.
    • (1980) Cancer Res , vol.40 , pp. 4343-4351
    • Groopman, J.D.1    Busby, W.F.2    Wogan, G.N.3
  • 11
    • 0026501157 scopus 로고
    • Molecular dosimetry of urinary aflatoxin-N 7-guanine and serum aflatoxin-albumin adducts predicts chemoprotection by 1,2-dithiole-3-thione in rats
    • Groopman, J. D., DeMatos, P., Egner, P. A., Love-Hunt, A., and Kensler, T. W. (1992a). Molecular dosimetry of urinary aflatoxin-N 7-guanine and serum aflatoxin-albumin adducts predicts chemoprotection by 1,2-dithiole-3-thione in rats. Carcinogenesis 13, 101-106.
    • (1992) Carcinogenesis , vol.13 , pp. 101-106
    • Groopman, J.D.1    DeMatos, P.2    Egner, P.A.3    Love-Hunt, A.4    Kensler, T.W.5
  • 13
    • 42949160573 scopus 로고    scopus 로고
    • Protective interventions to prevent aflatoxin-induced carcinogenesis in developing countries
    • Groopman, J. D., Kensler, T. W., and Wild, C. P. (2008). Protective interventions to prevent aflatoxin-induced carcinogenesis in developing countries. Annu. Rev. Public Health 29, 187-203.
    • (2008) Annu. Rev. Public Health , vol.29 , pp. 187-203
    • Groopman, J.D.1    Kensler, T.W.2    Wild, C.P.3
  • 15
    • 77955079408 scopus 로고    scopus 로고
    • Sulforaphane- and phenethyl isothiocyanate-induced inhibition of aflatoxin B1-mediated genotoxicity in human hepatocytes: role of GSTM1 genotype and CYP3A4 gene expression
    • Gross-Steinmeyer, K., Stapleton, P. L., Tracy, J. H., Bammler, T. K., Strom, S. C., and Eaton, D. L. (2010). Sulforaphane- and phenethyl isothiocyanate-induced inhibition of aflatoxin B1-mediated genotoxicity in human hepatocytes: role of GSTM1 genotype and CYP3A4 gene expression. Toxicol. Sci. 116, 422-432.
    • (2010) Toxicol. Sci. , vol.116 , pp. 422-432
    • Gross-Steinmeyer, K.1    Stapleton, P.L.2    Tracy, J.H.3    Bammler, T.K.4    Strom, S.C.5    Eaton, D.L.6
  • 16
    • 0017101746 scopus 로고
    • Effect of sex difference on the in vitro and in vivo metabolism of aflatoxin B1 by the rat
    • Gurtoo, H. L., and Motycka, L. (1976). Effect of sex difference on the in vitro and in vivo metabolism of aflatoxin B1 by the rat. Cancer Res. 36, 4663-4671.
    • (1976) Cancer Res , vol.36 , pp. 4663-4671
    • Gurtoo, H.L.1    Motycka, L.2
  • 17
    • 0016275313 scopus 로고
    • Glutathione S-transferases. The first enzymatic step in mercapturic acid formation
    • Habig, W. H., Pabst, M. J., and Jakoby, W. B. (1974). Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249, 7130-7139.
    • (1974) J. Biol. Chem , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 18
    • 0031661517 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in aflatoxin B1-treated cultured primary rat hepatocytes and Fischer 344 rats
    • Harris, A. J., Shaddock, J. G., Manjanatha, M. G., Lisenbey, J. A., and Casciano, D. A. (1998). Identification of differentially expressed genes in aflatoxin B1-treated cultured primary rat hepatocytes and Fischer 344 rats. Carcinogenesis 19, 1451-1458.
    • (1998) Carcinogenesis , vol.19 , pp. 1451-1458
    • Harris, A.J.1    Shaddock, J.G.2    Manjanatha, M.G.3    Lisenbey, J.A.4    Casciano, D.A.5
  • 19
    • 28644450910 scopus 로고    scopus 로고
    • Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin- DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, people's republic of China
    • Kensler, T. W., Chen, J. G., Egner, P. A., Fahey, J. W., Jacobson, L. P., Stephenson, K. K., Ye, L., Coady, J. L., Wang, J. B., Wu, Y., et al. (2005). Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin- DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, people's republic of China. Cancer Epidemiol. Biomarkers Prev. 14, 2605-2613.
    • (2005) Cancer Epidemiol. Biomarkers Prev. , vol.14 , pp. 2605-2613
    • Kensler, T.W.1    Chen, J.G.2    Egner, P.A.3    Fahey, J.W.4    Jacobson, L.P.5    Stephenson, K.K.6    Ye, L.7    Coady, J.L.8    Wang, J.B.9    Wu, Y.10
  • 20
    • 0022497046 scopus 로고
    • Modulation of aflatoxin metabolism, aflatoxin-N 7-guanine formation, and hepatic tumorigenesis in rats fed ethoxyquin: role of induction of glutathione S-transferases
    • Kensler, T. W., Egner, P. A., Davidson, N. E., Roebuck, B. D., Pikul, A., and Groopman, J. D. (1986). Modulation of aflatoxin metabolism, aflatoxin-N 7-guanine formation, and hepatic tumorigenesis in rats fed ethoxyquin: role of induction of glutathione S-transferases. Cancer Res. 46, 3924-3931.
    • (1986) Cancer Res , vol.46 , pp. 3924-3931
    • Kensler, T.W.1    Egner, P.A.2    Davidson, N.E.3    Roebuck, B.D.4    Pikul, A.5    Groopman, J.D.6
  • 21
    • 0026501721 scopus 로고
    • Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione
    • Kensler, T. W., Groopman, J. D., Eaton, D. L., Curphey, T. J., and Roebuck, B. D. (1992). Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione. Carcinogenesis 13, 95-100.
    • (1992) Carcinogenesis , vol.13 , pp. 95-100
    • Kensler, T.W.1    Groopman, J.D.2    Eaton, D.L.3    Curphey, T.J.4    Roebuck, B.D.5
  • 22
    • 0038049147 scopus 로고    scopus 로고
    • Translational strategies for cancer prevention in liver
    • Kensler, T. W., Qian, G. S., Chen, J. G., and Groopman, J. D. (2003). Translational strategies for cancer prevention in liver. Nature Reviews 3, 321-329.
    • (2003) Nature Reviews , vol.3 , pp. 321-329
    • Kensler, T.W.1    Qian, G.S.2    Chen, J.G.3    Groopman, J.D.4
  • 23
    • 79952088976 scopus 로고    scopus 로고
    • Aflatoxin: a 50 year odyssey of mechanistic and translational toxicology
    • Kensler, T. W., Roebuck, B. D., Wogan, G. N., and Groopman, J. D. (2011). Aflatoxin: a 50 year odyssey of mechanistic and translational toxicology. Toxicol. Sci. 120(supp. 1), S28-S48.
    • (2011) Toxicol. Sci. , vol.120 , Issue.SUPP. 1
    • Kensler, T.W.1    Roebuck, B.D.2    Wogan, G.N.3    Groopman, J.D.4
  • 24
    • 0034014663 scopus 로고    scopus 로고
    • Inhibition of human cytochrome P450 enzymes by 1,2-dithiole-3-thione, oltipraz and its derivatives, and sulforaphane
    • Langouet, S., Furge, L. L., Kerriguy, N., Nakamura, K., Guillouzo, A., and Guengerich, F. P. (2000). Inhibition of human cytochrome P450 enzymes by 1,2-dithiole-3-thione, oltipraz and its derivatives, and sulforaphane. Chem. Res. Toxicol. 13, 245-252.
    • (2000) Chem. Res. Toxicol. , vol.13 , pp. 245-252
    • Langouet, S.1    Furge, L.L.2    Kerriguy, N.3    Nakamura, K.4    Guillouzo, A.5    Guengerich, F.P.6
  • 26
    • 0015062553 scopus 로고
    • Absence of an effect of partial hepatectomy on aflatoxin B 1 carcinogenesis
    • Rogers, A. E., Kula, N. S., and Newberne, P. M. (1971). Absence of an effect of partial hepatectomy on aflatoxin B 1 carcinogenesis. Cancer Res. 31, 491-495.
    • (1971) Cancer Res , vol.31 , pp. 491-495
    • Rogers, A.E.1    Kula, N.S.2    Newberne, P.M.3
  • 27
    • 0014169657 scopus 로고
    • Dose-response characteristics of aflatoxin B1 carcinogenesis in the rat
    • Wogan, G. N., and Newberne, P. M. (1967). Dose-response characteristics of aflatoxin B1 carcinogenesis in the rat. Cancer Res. 27, 2370-2376.
    • (1967) Cancer Res , vol.27 , pp. 2370-2376
    • Wogan, G.N.1    Newberne, P.M.2
  • 28
    • 0028203252 scopus 로고
    • Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates
    • Zhang, Y., Kensler, T. W., Cho, C. G., Posner, G. H., and Talalay, P. (1994). Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates. Proc. Natl. Acad. Sci. U.S.A 91, 3147-3150.
    • (1994) Proc. Natl. Acad. Sci. U. S. A , vol.91 , pp. 3147-3150
    • Zhang, Y.1    Kensler, T.W.2    Cho, C.G.3    Posner, G.H.4    Talalay, P.5


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