-
1
-
-
0033864802
-
The molecular effects of acrolein
-
Kehrer J.P., Biswal S.S. The molecular effects of acrolein. Toxicol. Sci. 2000, 57:6-15.
-
(2000)
Toxicol. Sci.
, vol.57
, pp. 6-15
-
-
Kehrer, J.P.1
Biswal, S.S.2
-
2
-
-
38949113159
-
Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease
-
Stevens J.F., Maier C.S. Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease. Mol. Nutr. Food Res. 2008, 52:7-25.
-
(2008)
Mol. Nutr. Food Res.
, vol.52
, pp. 7-25
-
-
Stevens, J.F.1
Maier, C.S.2
-
4
-
-
0032568935
-
Acrolein is a product of lipid peroxidation reaction. Formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins
-
Uchida K., Kanematsu M., Morimitsu Y., Osawa T., Noguchi N., Niki E. Acrolein is a product of lipid peroxidation reaction. Formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins. J. Biol. Chem. 1998, 273:16058-16066.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16058-16066
-
-
Uchida, K.1
Kanematsu, M.2
Morimitsu, Y.3
Osawa, T.4
Noguchi, N.5
Niki, E.6
-
5
-
-
68849091099
-
The scientific basis of tobacco product regulation
-
WHO
-
WHO The scientific basis of tobacco product regulation. World Health Organization Technical Report Series 2008, 1-277.
-
(2008)
World Health Organization Technical Report Series
, pp. 1-277
-
-
-
7
-
-
0032905632
-
Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease
-
Calingasan N.Y., Uchida K., Gibson G.E. Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease. J. Neurochem. 1999, 72:751-756.
-
(1999)
J. Neurochem.
, vol.72
, pp. 751-756
-
-
Calingasan, N.Y.1
Uchida, K.2
Gibson, G.E.3
-
8
-
-
0035112495
-
Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures
-
Lovell M.A., Xie C., Markesbery W.R. Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures. Neurobiol. Aging 2001, 22:187-194.
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 187-194
-
-
Lovell, M.A.1
Xie, C.2
Markesbery, W.R.3
-
9
-
-
77957256030
-
Role of by-products of lipid oxidation in Alzheimer's disease brain: a focus on acrolein
-
Singh M., Dang T.N., Arseneault M., Ramassamy C. Role of by-products of lipid oxidation in Alzheimer's disease brain: a focus on acrolein. J. Alzheimers Dis. 2010, 21:741-756.
-
(2010)
J. Alzheimers Dis.
, vol.21
, pp. 741-756
-
-
Singh, M.1
Dang, T.N.2
Arseneault, M.3
Ramassamy, C.4
-
10
-
-
36749104186
-
In parkinsonian substantia nigra, alpha-synuclein is modified by acrolein, a lipid-peroxidation product, and accumulates in the dopamine neurons with inhibition of proteasome activity
-
Shamoto-Nagai M., Maruyama W., Hashizume Y., Yoshida M., Osawa T., Riederer P., Naoi M. In parkinsonian substantia nigra, alpha-synuclein is modified by acrolein, a lipid-peroxidation product, and accumulates in the dopamine neurons with inhibition of proteasome activity. J. Neural Transm. 2007, 114:1559-1567.
-
(2007)
J. Neural Transm.
, vol.114
, pp. 1559-1567
-
-
Shamoto-Nagai, M.1
Maruyama, W.2
Hashizume, Y.3
Yoshida, M.4
Osawa, T.5
Riederer, P.6
Naoi, M.7
-
11
-
-
4043151990
-
Detection of acrolein-lysine adducts in plasma low-density lipoprotein and in aorta of cyclophosphamide-administered rats
-
Arikketh D., Niranjali S., Devaraj H. Detection of acrolein-lysine adducts in plasma low-density lipoprotein and in aorta of cyclophosphamide-administered rats. Arch. Toxicol. 2004, 78:397-401.
-
(2004)
Arch. Toxicol.
, vol.78
, pp. 397-401
-
-
Arikketh, D.1
Niranjali, S.2
Devaraj, H.3
-
12
-
-
42549159857
-
Acrolein induces inflammatory response underlying endothelial dysfunction: a risk factor for atherosclerosis
-
Park Y.S., Taniguchi N. Acrolein induces inflammatory response underlying endothelial dysfunction: a risk factor for atherosclerosis. Ann. N. Y. Acad. Sci. 2008, 1126:185-189.
-
(2008)
Ann. N. Y. Acad. Sci.
, vol.1126
, pp. 185-189
-
-
Park, Y.S.1
Taniguchi, N.2
-
13
-
-
23744494889
-
Acrolein modifies apolipoprotein A-I in the human artery wall
-
Shao B., O'Brien K.D., McDonald T.O., Fu X., Oram J.F., Uchida K., Heinecke J.W. Acrolein modifies apolipoprotein A-I in the human artery wall. Ann. N. Y. Acad. Sci. 2005, 1043:396-403.
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1043
, pp. 396-403
-
-
Shao, B.1
O'Brien, K.D.2
McDonald, T.O.3
Fu, X.4
Oram, J.F.5
Uchida, K.6
Heinecke, J.W.7
-
14
-
-
0033113321
-
Carbonyl stress in the pathogenesis of diabetic nephropathy
-
Suzuki D., Miyata T. Carbonyl stress in the pathogenesis of diabetic nephropathy. Intern. Med. 1999, 38:309-314.
-
(1999)
Intern. Med.
, vol.38
, pp. 309-314
-
-
Suzuki, D.1
Miyata, T.2
-
15
-
-
0037295417
-
Increased urinary levels of pentosidine, pyrraline and acrolein adduct in type 2 diabetes
-
Daimon M., Sugiyama K., Kameda W., Saitoh T., Oizumi T., Hirata A., Yamaguchi H., Ohnuma H., Igarashi M., Kato T. Increased urinary levels of pentosidine, pyrraline and acrolein adduct in type 2 diabetes. Endocr. J. 2003, 50:61-67.
-
(2003)
Endocr. J.
, vol.50
, pp. 61-67
-
-
Daimon, M.1
Sugiyama, K.2
Kameda, W.3
Saitoh, T.4
Oizumi, T.5
Hirata, A.6
Yamaguchi, H.7
Ohnuma, H.8
Igarashi, M.9
Kato, T.10
-
16
-
-
80052605887
-
Acrolein induced DNA damage, mutagenicity and effect on DNA repair
-
Tang M.S., Wang H.T., Hu Y., Chen W.S., Akao M., Feng Z., Hu W. Acrolein induced DNA damage, mutagenicity and effect on DNA repair. Mol. Nutr. Food Res. 2011, 55:1291-1300.
-
(2011)
Mol. Nutr. Food Res.
, vol.55
, pp. 1291-1300
-
-
Tang, M.S.1
Wang, H.T.2
Hu, Y.3
Chen, W.S.4
Akao, M.5
Feng, Z.6
Hu, W.7
-
17
-
-
68949173804
-
Acrolein induces a cellular stress response and triggers mitochondrial apoptosis in A549 cells
-
Roy J., Pallepati P., Bettaieb A., Tanel A., Averill-Bates D.A. Acrolein induces a cellular stress response and triggers mitochondrial apoptosis in A549 cells. Chem. Biol. Interact. 2009, 181:154-167.
-
(2009)
Chem. Biol. Interact.
, vol.181
, pp. 154-167
-
-
Roy, J.1
Pallepati, P.2
Bettaieb, A.3
Tanel, A.4
Averill-Bates, D.A.5
-
18
-
-
62549138221
-
Acrolein activates matrix metalloproteinases by increasing reactive oxygen species in macrophages
-
O'Toole T.E., Zheng Y.T., Hellmann J., Conklin D.J., Barski O., Bhatnagar A. Acrolein activates matrix metalloproteinases by increasing reactive oxygen species in macrophages. Toxicol. Appl. Pharmacol. 2009, 236:194-201.
-
(2009)
Toxicol. Appl. Pharmacol.
, vol.236
, pp. 194-201
-
-
O'Toole, T.E.1
Zheng, Y.T.2
Hellmann, J.3
Conklin, D.J.4
Barski, O.5
Bhatnagar, A.6
-
19
-
-
67650739174
-
Protective effect of lipoic acid against acrolein-induced cytotoxicity in IMR-90 human fibroblasts
-
Jia L., Zhang Z., Zhai L., Bai Y. Protective effect of lipoic acid against acrolein-induced cytotoxicity in IMR-90 human fibroblasts. J. Nutr. Sci. Vitaminol. (Tokyo) 2009, 55:126-130.
-
(2009)
J. Nutr. Sci. Vitaminol. (Tokyo)
, vol.55
, pp. 126-130
-
-
Jia, L.1
Zhang, Z.2
Zhai, L.3
Bai, Y.4
-
20
-
-
48849100392
-
The role of oxidative stress in acrolein-induced DNA damage in HepG2 cells
-
Li L., Jiang L., Geng C., Cao J., Zhong L. The role of oxidative stress in acrolein-induced DNA damage in HepG2 cells. Free Radic. Res. 2008, 42:354-361.
-
(2008)
Free Radic. Res.
, vol.42
, pp. 354-361
-
-
Li, L.1
Jiang, L.2
Geng, C.3
Cao, J.4
Zhong, L.5
-
21
-
-
0031214090
-
Acrolein-induced cell death in human alveolar macrophages
-
Li L., Hamilton R.F., Taylor D.E., Holian A. Acrolein-induced cell death in human alveolar macrophages. Toxicol. Appl. Pharmacol. 1997, 145:331-339.
-
(1997)
Toxicol. Appl. Pharmacol.
, vol.145
, pp. 331-339
-
-
Li, L.1
Hamilton, R.F.2
Taylor, D.E.3
Holian, A.4
-
22
-
-
0037168998
-
Acrolein-induced cytotoxicity in cultured human bronchial epithelial cells. Modulation by alpha-tocopherol and ascorbic acid
-
Nardini M., Finkelstein E.I., Reddy S., Valacchi G., Traber M., Cross C.E., van der Vliet A. Acrolein-induced cytotoxicity in cultured human bronchial epithelial cells. Modulation by alpha-tocopherol and ascorbic acid. Toxicology 2002, 170:173-185.
-
(2002)
Toxicology
, vol.170
, pp. 173-185
-
-
Nardini, M.1
Finkelstein, E.I.2
Reddy, S.3
Valacchi, G.4
Traber, M.5
Cross, C.E.6
van der Vliet, A.7
-
23
-
-
17444421537
-
The aldehyde acrolein induces apoptosis via activation of the mitochondrial pathway
-
Tanel A., Averill-Bates D.A. The aldehyde acrolein induces apoptosis via activation of the mitochondrial pathway. Biochim. Biophys. Acta 2005, 1743:255-267.
-
(2005)
Biochim. Biophys. Acta
, vol.1743
, pp. 255-267
-
-
Tanel, A.1
Averill-Bates, D.A.2
-
24
-
-
33745790878
-
Acrolein-mediated mechanisms of neuronal death
-
Liu-Snyder P., McNally H., Shi R., Borgens R.B. Acrolein-mediated mechanisms of neuronal death. J. Neurosci. Res. 2006, 84:209-218.
-
(2006)
J. Neurosci. Res.
, vol.84
, pp. 209-218
-
-
Liu-Snyder, P.1
McNally, H.2
Shi, R.3
Borgens, R.B.4
-
25
-
-
33846419151
-
GSH-dependent regulation of Fas-mediated caspase-8 activation by acrolein
-
Hristova M., Heuvelmans S., van der Vliet A. GSH-dependent regulation of Fas-mediated caspase-8 activation by acrolein. FEBS Lett. 2007, 581:361-367.
-
(2007)
FEBS Lett.
, vol.581
, pp. 361-367
-
-
Hristova, M.1
Heuvelmans, S.2
van der Vliet, A.3
-
26
-
-
0037154352
-
Acrolein-induced cell death: a caspase-influenced decision between apoptosis and oncosis/necrosis
-
Kern J.C., Kehrer J.P. Acrolein-induced cell death: a caspase-influenced decision between apoptosis and oncosis/necrosis. Chem. Biol. Interact. 2002, 139:79-95.
-
(2002)
Chem. Biol. Interact.
, vol.139
, pp. 79-95
-
-
Kern, J.C.1
Kehrer, J.P.2
-
27
-
-
41949116699
-
Protein alkylation, transcriptional responses and cytochrome c release during acrolein toxicity in A549 cells: influence of nucleophilic culture media constituents
-
Thompson C.A., Burcham P.C. Protein alkylation, transcriptional responses and cytochrome c release during acrolein toxicity in A549 cells: influence of nucleophilic culture media constituents. Toxicol. in Vitro 2008, 22:844-853.
-
(2008)
Toxicol. in Vitro
, vol.22
, pp. 844-853
-
-
Thompson, C.A.1
Burcham, P.C.2
-
28
-
-
48849117849
-
Dose response considerations in risk assessment-an overview of recent ILSI activities
-
Holsapple M.P., Wallace K.B. Dose response considerations in risk assessment-an overview of recent ILSI activities. Toxicol. Lett. 2008, 180:85-92.
-
(2008)
Toxicol. Lett.
, vol.180
, pp. 85-92
-
-
Holsapple, M.P.1
Wallace, K.B.2
-
29
-
-
0034456207
-
Oxidative stress, antioxidant defenses, and damage removal, repair, and replacement systems
-
Davies K.J. Oxidative stress, antioxidant defenses, and damage removal, repair, and replacement systems. IUBMB Life 2000, 50:279-289.
-
(2000)
IUBMB Life
, vol.50
, pp. 279-289
-
-
Davies, K.J.1
-
30
-
-
78650782391
-
Anti-apoptosis and cell survival: a review
-
Portt L., Norman G., Clapp C., Greenwood M., Greenwood M.T. Anti-apoptosis and cell survival: a review. Biochim. Biophys. Acta 2010, 1813:238-259.
-
(2010)
Biochim. Biophys. Acta
, vol.1813
, pp. 238-259
-
-
Portt, L.1
Norman, G.2
Clapp, C.3
Greenwood, M.4
Greenwood, M.T.5
-
32
-
-
0346250162
-
Regulation of apoptosis by endoplasmic reticulum pathways
-
Breckenridge D.G., Germain M., Mathai J.P., Nguyen M., Shore G.C. Regulation of apoptosis by endoplasmic reticulum pathways. Oncogene 2003, 22:8608-8618.
-
(2003)
Oncogene
, vol.22
, pp. 8608-8618
-
-
Breckenridge, D.G.1
Germain, M.2
Mathai, J.P.3
Nguyen, M.4
Shore, G.C.5
-
33
-
-
13144266681
-
Protein-bound acrolein: potential markers for oxidative stress
-
Uchida K., Kanematsu M., Sakai K., Matsuda T., Hattori N., Mizuno Y., Suzuki D., Miyata T., Noguchi N., Niki E., Osawa T. Protein-bound acrolein: potential markers for oxidative stress. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:4882-4887.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 4882-4887
-
-
Uchida, K.1
Kanematsu, M.2
Sakai, K.3
Matsuda, T.4
Hattori, N.5
Mizuno, Y.6
Suzuki, D.7
Miyata, T.8
Noguchi, N.9
Niki, E.10
Osawa, T.11
-
34
-
-
33644845649
-
Hydralazine inhibits rapid acrolein-induced protein oligomerization: role of aldehyde scavenging and adduct trapping in cross-link blocking and cytoprotection
-
Burcham P.C., Pyke S.M. Hydralazine inhibits rapid acrolein-induced protein oligomerization: role of aldehyde scavenging and adduct trapping in cross-link blocking and cytoprotection. Mol. Pharmacol. 2006, 69:1056-1065.
-
(2006)
Mol. Pharmacol.
, vol.69
, pp. 1056-1065
-
-
Burcham, P.C.1
Pyke, S.M.2
-
35
-
-
0033561295
-
Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells
-
Samali A., Cai J., Zhivotovsky B., Jones D.P., Orrenius S. Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells. EMBO J. 1999, 18:2040-2048.
-
(1999)
EMBO J.
, vol.18
, pp. 2040-2048
-
-
Samali, A.1
Cai, J.2
Zhivotovsky, B.3
Jones, D.P.4
Orrenius, S.5
-
36
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
37
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
38
-
-
0033634641
-
Perk is essential for translational regulation and cell survival during the unfolded protein response
-
Harding H.P., Zhang Y., Bertolotti A., Zeng H., Ron D. Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol. Cell 2000, 5:897-904.
-
(2000)
Mol. Cell
, vol.5
, pp. 897-904
-
-
Harding, H.P.1
Zhang, Y.2
Bertolotti, A.3
Zeng, H.4
Ron, D.5
-
39
-
-
4444232905
-
The unfolded protein response-a stress signaling pathway of the endoplasmic reticulum
-
Shen X., Zhang K., Kaufman R.J. The unfolded protein response-a stress signaling pathway of the endoplasmic reticulum. J. Chem. Neuroanat. 2004, 28:79-92.
-
(2004)
J. Chem. Neuroanat.
, vol.28
, pp. 79-92
-
-
Shen, X.1
Zhang, K.2
Kaufman, R.J.3
-
40
-
-
0031106374
-
A rapid increase in the level of binding protein (BiP) is accompanied by synthesis and degradation of storage proteins in pumpkin cotyledons
-
Hatano K., Shimada T., Hiraiwa N., Nishimura M., Hara-Nishimura I. A rapid increase in the level of binding protein (BiP) is accompanied by synthesis and degradation of storage proteins in pumpkin cotyledons. Plant Cell Physiol. 1997, 38:344-351.
-
(1997)
Plant Cell Physiol.
, vol.38
, pp. 344-351
-
-
Hatano, K.1
Shimada, T.2
Hiraiwa, N.3
Nishimura, M.4
Hara-Nishimura, I.5
-
41
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
Oyadomari S., Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ. 2004, 11:381-389.
-
(2004)
Cell Death Differ.
, vol.11
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
42
-
-
77955965172
-
Cellular stress responses: cell survival and cell death
-
Fulda S., Gorman A.M., Hori O., Samali A. Cellular stress responses: cell survival and cell death. Int. J. Cell Biol. 2010, 2010:214074.
-
(2010)
Int. J. Cell Biol.
, vol.2010
, pp. 214074
-
-
Fulda, S.1
Gorman, A.M.2
Hori, O.3
Samali, A.4
-
43
-
-
0034698878
-
Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
-
Nakagawa T., Yuan J. Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J. Cell Biol. 2000, 150:887-894.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 887-894
-
-
Nakagawa, T.1
Yuan, J.2
-
44
-
-
33744918550
-
Ubiquitous calpains promote caspase-12 and JNK activation during endoplasmic reticulum stress-induced apoptosis
-
Tan Y., Dourdin N., Wu C., De Veyra T., Elce J.S., Greer P.A. Ubiquitous calpains promote caspase-12 and JNK activation during endoplasmic reticulum stress-induced apoptosis. J. Biol. Chem. 2006, 281:16016-16024.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 16016-16024
-
-
Tan, Y.1
Dourdin, N.2
Wu, C.3
De Veyra, T.4
Elce, J.S.5
Greer, P.A.6
-
45
-
-
4444253303
-
Survival and apoptosis signals in ER stress: the role of protein kinases
-
Kadowaki H., Nishitoh H., Ichijo H. Survival and apoptosis signals in ER stress: the role of protein kinases. J. Chem. Neuroanat. 2004, 28:93-100.
-
(2004)
J. Chem. Neuroanat.
, vol.28
, pp. 93-100
-
-
Kadowaki, H.1
Nishitoh, H.2
Ichijo, H.3
-
46
-
-
56749172400
-
Calcium-bound structure of calpain and its mechanism of inhibition by calpastatin
-
Hanna R.A., Campbell R.L., Davies P.L. Calcium-bound structure of calpain and its mechanism of inhibition by calpastatin. Nature 2008, 456:409-412.
-
(2008)
Nature
, vol.456
, pp. 409-412
-
-
Hanna, R.A.1
Campbell, R.L.2
Davies, P.L.3
-
48
-
-
0028856840
-
Dietary antioxidants and cigarette smoke-induced biomolecular damage: a complex interaction
-
Eiserich J.P., van der Vliet A., Handelman G.J., Halliwell B., Cross C.E. Dietary antioxidants and cigarette smoke-induced biomolecular damage: a complex interaction. Am. J. Clin. Nutr. 1995, 62(6 Suppl.):1490S-1500S.
-
(1995)
Am. J. Clin. Nutr.
, vol.62
, Issue.6 SUPPL.
-
-
Eiserich, J.P.1
van der Vliet, A.2
Handelman, G.J.3
Halliwell, B.4
Cross, C.E.5
-
49
-
-
0036143302
-
A fatal human intoxication with the herbicide allyl alcohol (2-propen-1-ol)
-
Toennes S.W., Schmidt K., Fandiño A.S., Kauert G.F. A fatal human intoxication with the herbicide allyl alcohol (2-propen-1-ol). J. Anal. Toxicol. 2002, 26:55-57.
-
(2002)
J. Anal. Toxicol.
, vol.26
, pp. 55-57
-
-
Toennes, S.W.1
Schmidt, K.2
Fandiño, A.S.3
Kauert, G.F.4
-
50
-
-
33947412631
-
Inhibition of acrolein-induced apoptosis by the antioxidant N-acetylcysteine
-
Tanel A., Averill-Bates D.A. Inhibition of acrolein-induced apoptosis by the antioxidant N-acetylcysteine. J. Pharmacol. Exp. Ther. 2007, 321:73-83.
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.321
, pp. 73-83
-
-
Tanel, A.1
Averill-Bates, D.A.2
-
51
-
-
0036168606
-
Inhibition of cell proliferation and AP-1 activity by acrolein in human A549 lung adenocarcinoma cells due to thiol imbalance and covalent modifications
-
Biswal S., Acquaah-Mensah G., Datta K., Wu X., Kehrer J.P. Inhibition of cell proliferation and AP-1 activity by acrolein in human A549 lung adenocarcinoma cells due to thiol imbalance and covalent modifications. Chem. Res. Toxicol. 2002, 15:180-186.
-
(2002)
Chem. Res. Toxicol.
, vol.15
, pp. 180-186
-
-
Biswal, S.1
Acquaah-Mensah, G.2
Datta, K.3
Wu, X.4
Kehrer, J.P.5
-
52
-
-
0037008669
-
Thiolation of protein-bound carcinogenic aldehyde. An electrophilic acrolein-lysine adduct that covalently binds to thiols
-
Furuhata A., Nakamura M., Osawa T., Uchida K. Thiolation of protein-bound carcinogenic aldehyde. An electrophilic acrolein-lysine adduct that covalently binds to thiols. J. Biol. Chem. 2002, 277:27919-27926.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 27919-27926
-
-
Furuhata, A.1
Nakamura, M.2
Osawa, T.3
Uchida, K.4
-
53
-
-
84867758123
-
Chaperone heat shock protein 90 mobilization and hydralazine cytoprotection against acrolein-induced carbonyl stress
-
Burcham P.C., Raso A., Kaminskas L.M. Chaperone heat shock protein 90 mobilization and hydralazine cytoprotection against acrolein-induced carbonyl stress. Mol. Pharmacol. 2012, 82:876-886.
-
(2012)
Mol. Pharmacol.
, vol.82
, pp. 876-886
-
-
Burcham, P.C.1
Raso, A.2
Kaminskas, L.M.3
-
54
-
-
84875221631
-
Acrolein and chloroacetaldehyde: an examination of the cell and cell-free biomarkers of toxicity
-
MacAllister S.L., Martin-Brisac N., Lau V., Yang K., O'Brien P.J. Acrolein and chloroacetaldehyde: an examination of the cell and cell-free biomarkers of toxicity. Chem. Biol. Interact. 2013, 202:259-266.
-
(2013)
Chem. Biol. Interact.
, vol.202
, pp. 259-266
-
-
MacAllister, S.L.1
Martin-Brisac, N.2
Lau, V.3
Yang, K.4
O'Brien, P.J.5
-
56
-
-
0033208953
-
Role and regulation of the ER chaperone BiP
-
Gething M.J. Role and regulation of the ER chaperone BiP. Semin. Cell Dev. Biol. 1999, 10:465-472.
-
(1999)
Semin. Cell Dev. Biol.
, vol.10
, pp. 465-472
-
-
Gething, M.J.1
-
57
-
-
0034282912
-
Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response
-
Wang Y., Shen J., Arenzana N., Tirasophon W., Kaufman R.J., Prywes R. Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response. J. Biol. Chem. 2000, 275:27013-27020.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 27013-27020
-
-
Wang, Y.1
Shen, J.2
Arenzana, N.3
Tirasophon, W.4
Kaufman, R.J.5
Prywes, R.6
-
58
-
-
0141752795
-
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
-
Cullinan S.B., Zhang D., Hannink M., Arvisais E., Kaufman R.J., Diehl J.A. Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol. Cell. Biol. 2003, 23:7198-7209.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 7198-7209
-
-
Cullinan, S.B.1
Zhang, D.2
Hannink, M.3
Arvisais, E.4
Kaufman, R.J.5
Diehl, J.A.6
-
59
-
-
57149117113
-
Role of endoplasmic reticulum stress in acrolein-induced endothelial activation
-
Haberzettl P., Vladykovskaya E., Srivastava S., Bhatnagar A. Role of endoplasmic reticulum stress in acrolein-induced endothelial activation. Toxicol. Appl. Pharmacol. 2009, 234:14-24.
-
(2009)
Toxicol. Appl. Pharmacol.
, vol.234
, pp. 14-24
-
-
Haberzettl, P.1
Vladykovskaya, E.2
Srivastava, S.3
Bhatnagar, A.4
-
60
-
-
84867748150
-
Acrolein cytotoxicity in hepatocytes involves endoplasmic reticulum stress, mitochondrial dysfunction and oxidative stress
-
Mohammad M.K., Avila D., Zhang J., Barve S., Arteel G., McClain C., Joshi-Barve S. Acrolein cytotoxicity in hepatocytes involves endoplasmic reticulum stress, mitochondrial dysfunction and oxidative stress. Toxicol. Appl. Pharmacol. 2012, 265:73-82.
-
(2012)
Toxicol. Appl. Pharmacol.
, vol.265
, pp. 73-82
-
-
Mohammad, M.K.1
Avila, D.2
Zhang, J.3
Barve, S.4
Arteel, G.5
McClain, C.6
Joshi-Barve, S.7
-
61
-
-
33745322846
-
The future of toxicology-does it matter how cells die?
-
Orrenius S., Zhivotovsky B. The future of toxicology-does it matter how cells die?. Chem. Res. Toxicol. 2006, 19:729-733.
-
(2006)
Chem. Res. Toxicol.
, vol.19
, pp. 729-733
-
-
Orrenius, S.1
Zhivotovsky, B.2
-
62
-
-
84861709854
-
Acrolein induces endoplasmic reticulum stress and causes airspace enlargement
-
Kitaguchi Y., Taraseviciene-Stewart L., Hanaoka M., Natarajan R., Kraskauskas D., Voelkel N.F. Acrolein induces endoplasmic reticulum stress and causes airspace enlargement. PLoS One 2012, 7:e38038.
-
(2012)
PLoS One
, vol.7
-
-
Kitaguchi, Y.1
Taraseviciene-Stewart, L.2
Hanaoka, M.3
Natarajan, R.4
Kraskauskas, D.5
Voelkel, N.F.6
-
63
-
-
77958126450
-
Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders
-
Calabrese V., Cornelius C., Dinkova-Kostova A.T., Calabrese E.J., Mattson M.P. Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders. Antioxid. Redox Signal. 2010, 13:1763-1811.
-
(2010)
Antioxid. Redox Signal.
, vol.13
, pp. 1763-1811
-
-
Calabrese, V.1
Cornelius, C.2
Dinkova-Kostova, A.T.3
Calabrese, E.J.4
Mattson, M.P.5
-
64
-
-
33745986025
-
Upregulation of endothelial heme oxygenase-1 expression through the activation of the JNK pathway by sublethal concentrations of acrolein
-
Wu C.C., Hsieh C.W., Lai P.H., Lin J.B., Liu Y.C., Wung B.S. Upregulation of endothelial heme oxygenase-1 expression through the activation of the JNK pathway by sublethal concentrations of acrolein. Toxicol. Appl. Pharmacol. 2006, 214:244-252.
-
(2006)
Toxicol. Appl. Pharmacol.
, vol.214
, pp. 244-252
-
-
Wu, C.C.1
Hsieh, C.W.2
Lai, P.H.3
Lin, J.B.4
Liu, Y.C.5
Wung, B.S.6
-
65
-
-
79960746567
-
Regulation of redox-sensitive signaling pathways in rat primary astrocytes following acrolein exposure
-
Dang T.N., Arseneault M., Ramassamy C. Regulation of redox-sensitive signaling pathways in rat primary astrocytes following acrolein exposure. J. Alzheimers Dis. 2011, 25:263-277.
-
(2011)
J. Alzheimers Dis.
, vol.25
, pp. 263-277
-
-
Dang, T.N.1
Arseneault, M.2
Ramassamy, C.3
-
66
-
-
34250758642
-
ER stress triggers apoptosis by activating BH3-only protein Bim
-
Puthalakath H., O'Reilly L.A., Gunn P., Lee L., Kelly P.N., Huntington N.D., Hughes P.D., Michalak E.M., McKimm-Breschkin J., Motoyama N., Gotoh T., Akira S., Bouillet P., Strasser A. ER stress triggers apoptosis by activating BH3-only protein Bim. Cell 2007, 129:1337-1349.
-
(2007)
Cell
, vol.129
, pp. 1337-1349
-
-
Puthalakath, H.1
O'Reilly, L.A.2
Gunn, P.3
Lee, L.4
Kelly, P.N.5
Huntington, N.D.6
Hughes, P.D.7
Michalak, E.M.8
McKimm-Breschkin, J.9
Motoyama, N.10
Gotoh, T.11
Akira, S.12
Bouillet, P.13
Strasser, A.14
-
67
-
-
80053371703
-
Activation of ER stress and apoptosis by hydrogen peroxide in HeLa cells: protective role of mild heat preconditioning at 40°C
-
Pallepati P., Averill-Bates D.A. Activation of ER stress and apoptosis by hydrogen peroxide in HeLa cells: protective role of mild heat preconditioning at 40°C. Biochim. Biophys. Acta 2011, 1813:1987-1999.
-
(2011)
Biochim. Biophys. Acta
, vol.1813
, pp. 1987-1999
-
-
Pallepati, P.1
Averill-Bates, D.A.2
-
68
-
-
77950888687
-
A549 cells undergo apoptosis through the death receptor pathway upon exposure to acrolein: role of p53
-
Roy J., Pallepati P., Bettaieb A., Averill-Bates D.A. A549 cells undergo apoptosis through the death receptor pathway upon exposure to acrolein: role of p53. Can. J. Physiol. Pharmacol. 2010, 88:353-368.
-
(2010)
Can. J. Physiol. Pharmacol.
, vol.88
, pp. 353-368
-
-
Roy, J.1
Pallepati, P.2
Bettaieb, A.3
Averill-Bates, D.A.4
-
69
-
-
33847291268
-
Activation of the death receptor pathway of apoptosis by the aldehyde acrolein
-
Tanel A., Averill-Bates D.A. Activation of the death receptor pathway of apoptosis by the aldehyde acrolein. Free Radic. Biol. Med. 2007, 42:798-810.
-
(2007)
Free Radic. Biol. Med.
, vol.42
, pp. 798-810
-
-
Tanel, A.1
Averill-Bates, D.A.2
-
70
-
-
34249844568
-
Clinical pharmacology of cyclophosphamide and ifosfamide
-
Zhang J., Tian Q., Zhou S. Clinical pharmacology of cyclophosphamide and ifosfamide. Curr. Drug Ther. 2006, 1:55-84.
-
(2006)
Curr. Drug Ther.
, vol.1
, pp. 55-84
-
-
Zhang, J.1
Tian, Q.2
Zhou, S.3
-
71
-
-
4143153834
-
Polyamines and cancer: minireview article
-
Bachrach U. Polyamines and cancer: minireview article. Amino Acids 2004, 26:307-309.
-
(2004)
Amino Acids
, vol.26
, pp. 307-309
-
-
Bachrach, U.1
|