-
1
-
-
0038337815
-
The calpain system
-
Goll, D. E., Thompson, V. F., Li, H., Wei, W. & Cong, J. The calpain system. Physiol. Rev. 83, 731-801 (2003).
-
(2003)
Physiol. Rev
, vol.83
, pp. 731-801
-
-
Goll, D.E.1
Thompson, V.F.2
Li, H.3
Wei, W.4
Cong, J.5
-
2
-
-
0036168356
-
Cutting to the chase: Calpain proteases in cell motility
-
Glading, A., Lauffenburger, D. A. & Wells, A. Cutting to the chase: Calpain proteases in cell motility. Trends Cell Biol. 12, 46-54 (2002).
-
(2002)
Trends Cell Biol
, vol.12
, pp. 46-54
-
-
Glading, A.1
Lauffenburger, D.A.2
Wells, A.3
-
3
-
-
26244434596
-
Regulating cell migration: Calpains make the cut
-
Franco, S. J. & Huttenlocher, A. Regulating cell migration: Calpains make the cut. J. Cell Sci. 118, 3829-3838 (2005).
-
(2005)
J. Cell Sci
, vol.118
, pp. 3829-3838
-
-
Franco, S.J.1
Huttenlocher, A.2
-
4
-
-
33846536286
-
NMDA-receptor activation induces calpain-mediated beta-catenin cleavages for triggering gene expression
-
Abe, K. & Takeichi, M. NMDA-receptor activation induces calpain-mediated beta-catenin cleavages for triggering gene expression. Neuron 53, 387-397 (2007).
-
(2007)
Neuron
, vol.53
, pp. 387-397
-
-
Abe, K.1
Takeichi, M.2
-
5
-
-
3242798339
-
Interaction of calpastatin with calpain: A review
-
Wendt, A., Thompson, V. F. & Goll, D. E. Interaction of calpastatin with calpain: A review. Biol. Chem. 385, 465-472 (2004).
-
(2004)
Biol. Chem
, vol.385
, pp. 465-472
-
-
Wendt, A.1
Thompson, V.F.2
Goll, D.E.3
-
6
-
-
34250201882
-
Calpastatin simultaneously binds four calpains with different kinetic constants
-
Hanna, R. A., Garcia-Diaz, B. E. & Davies, P. L. Calpastatin simultaneously binds four calpains with different kinetic constants. FEBS Lett. 581, 2894-2898 (2007).
-
(2007)
FEBS Lett
, vol.581
, pp. 2894-2898
-
-
Hanna, R.A.1
Garcia-Diaz, B.E.2
Davies, P.L.3
-
7
-
-
0037424522
-
Structural determinants of the calpain inhibitory activity of calpastatin peptide B27-WT
-
Betts, R., Weinsheimer, S., Blouse, G. E. & Anagli, J. Structural determinants of the calpain inhibitory activity of calpastatin peptide B27-WT. J. Biol. Chem. 278, 7800-7809 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 7800-7809
-
-
Betts, R.1
Weinsheimer, S.2
Blouse, G.E.3
Anagli, J.4
-
8
-
-
0037453230
-
A structural model for the inhibition of calpain by calpastatin: Crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor
-
Todd, B. et al. A structural model for the inhibition of calpain by calpastatin: Crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor. J. Mol. Biol. 328, 131-146 (2003).
-
(2003)
J. Mol. Biol
, vol.328
, pp. 131-146
-
-
Todd, B.1
-
9
-
-
37349103987
-
Inhibition of human mu-calpain by conformationally constrained calpastatin peptides
-
Pfizer, J., Assfalg-Machleidt, I., Machleidt, W. & Schaschke, N. Inhibition of human mu-calpain by conformationally constrained calpastatin peptides. Biol. Chem. 389, 83-90 (2008).
-
(2008)
Biol. Chem
, vol.389
, pp. 83-90
-
-
Pfizer, J.1
Assfalg-Machleidt, I.2
Machleidt, W.3
Schaschke, N.4
-
10
-
-
56749143763
-
Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains
-
doi:10.1038/nature07353 this issue
-
Moldoveanu, T., Gehring, K. & Green, D. R. Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains. Nature doi:10.1038/nature07353 (this issue).
-
Nature
-
-
Moldoveanu, T.1
Gehring, K.2
Green, D.R.3
-
11
-
-
12944297732
-
2+ exchanger in excitotoxicity
-
2+ exchanger in excitotoxicity. Cell 120, 275-285 (2005).
-
(2005)
Cell
, vol.120
, pp. 275-285
-
-
Bano, D.1
-
12
-
-
12444294425
-
Overexpression of calpastatin by gene transfer prevents troponin I degradation and ameliorates contractile dysfunction in rat hearts subjected to ischemia/reperfusion
-
Maekawa, A. et al. Overexpression of calpastatin by gene transfer prevents troponin I degradation and ameliorates contractile dysfunction in rat hearts subjected to ischemia/reperfusion. J. Mol. Cell. Cardiol. 35, 1277-1284 (2003).
-
(2003)
J. Mol. Cell. Cardiol
, vol.35
, pp. 1277-1284
-
-
Maekawa, A.1
-
13
-
-
27844462036
-
Developments in the design and synthesis of calpain inhibitors
-
Neffe, A. T. & Abell, A. D. Developments in the design and synthesis of calpain inhibitors. Curr. Opin. Drug Discov. Dev. 8, 684-700 (2005).
-
(2005)
Curr. Opin. Drug Discov. Dev
, vol.8
, pp. 684-700
-
-
Neffe, A.T.1
Abell, A.D.2
-
14
-
-
0033573028
-
Crystal structure of calpain reveals the structural basis for Ca(2+)-dependent protease activity and a novel mode of enzyme activation
-
Hosfield, C. M., Elce, J. S., Davies, P. L. & Jia, Z. Crystal structure of calpain reveals the structural basis for Ca(2+)-dependent protease activity and a novel mode of enzyme activation. EMBO J. 18, 6880-6889 (1999).
-
(1999)
EMBO J
, vol.18
, pp. 6880-6889
-
-
Hosfield, C.M.1
Elce, J.S.2
Davies, P.L.3
Jia, Z.4
-
15
-
-
12944300453
-
The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium
-
Strobl, S. et al. The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium. Proc. Natl Acad. Sci. USA 97, 588-592 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 588-592
-
-
Strobl, S.1
-
16
-
-
0028965234
-
Preference of calcium-dependent interactions between calmodulin-like domains of calpain and calpastatin subdomains
-
Takano, E., Ma, H., Yang, H. Q., Maki, M. & Hatanaka, M. Preference of calcium-dependent interactions between calmodulin-like domains of calpain and calpastatin subdomains. FEBS Lett. 362, 93-97 (1995).
-
(1995)
FEBS Lett
, vol.362
, pp. 93-97
-
-
Takano, E.1
Ma, H.2
Yang, H.Q.3
Maki, M.4
Hatanaka, M.5
-
17
-
-
0037040423
-
A Ca(2+) switch aligns the active site of calpain
-
Moldoveanu, T. et al. A Ca(2+) switch aligns the active site of calpain. Cell 108, 649-660 (2002).
-
(2002)
Cell
, vol.108
, pp. 649-660
-
-
Moldoveanu, T.1
-
18
-
-
0027940509
-
Domain structure of calpain: Mapping the binding site for calpastatin
-
Croall, D. E. & McGrody, K. S. Domain structure of calpain: Mapping the binding site for calpastatin. Biochemistry 33, 13223-13230 (1994).
-
(1994)
Biochemistry
, vol.33
, pp. 13223-13230
-
-
Croall, D.E.1
McGrody, K.S.2
-
19
-
-
0028880896
-
Recombinant calpain II: Improved expression systems and production of a C105A active-site mutant for crystallography
-
Elce, J. S., Hegadorn, C., Gauthier, S., Vince, J. W. & Davies, P. L. Recombinant calpain II: Improved expression systems and production of a C105A active-site mutant for crystallography. Protein Eng. 8, 843-848 (1995).
-
(1995)
Protein Eng
, vol.8
, pp. 843-848
-
-
Elce, J.S.1
Hegadorn, C.2
Gauthier, S.3
Vince, J.W.4
Davies, P.L.5
-
20
-
-
0024844775
-
Inhibition of calpain by a synthetic oligopeptide corresponding to an exon of the human calpastatin gene
-
Maki, M. et al. Inhibition of calpain by a synthetic oligopeptide corresponding to an exon of the human calpastatin gene. J. Biol. Chem. 264, 18866-18869 (1989).
-
(1989)
J. Biol. Chem
, vol.264
, pp. 18866-18869
-
-
Maki, M.1
-
21
-
-
28844491633
-
Determination of peptide substrate specificity for mu-calpain by a peptide library-based approach: The importance of primed side interactions
-
Cuerrier, D., Moldoveanu, T. & Davies, P. L. Determination of peptide substrate specificity for mu-calpain by a peptide library-based approach: The importance of primed side interactions. J. Biol. Chem. 280, 40632-40641 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 40632-40641
-
-
Cuerrier, D.1
Moldoveanu, T.2
Davies, P.L.3
-
22
-
-
0025934130
-
Structure of the active 27-residue fragment of human calpastatin
-
Ishima, R. et al. Structure of the active 27-residue fragment of human calpastatin. FEBS Lett. 294, 64-66 (1991).
-
(1991)
FEBS Lett
, vol.294
, pp. 64-66
-
-
Ishima, R.1
-
23
-
-
17844410707
-
The many faces of protease-protein inhibitor interaction
-
Otlewski, J., Filip, J., Zakrzewska, M. & Oleksy, A. The many faces of protease-protein inhibitor interaction. EMBO J. 24, 1304-1310 (2005).
-
(2005)
EMBO J
, vol.24
, pp. 1304-1310
-
-
Otlewski, J.1
Filip, J.2
Zakrzewska, M.3
Oleksy, A.4
-
24
-
-
0033950453
-
The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix
-
Li, M. et al. The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix. Nature Struct. Biol. 7, 113-117 (2000).
-
(2000)
Nature Struct. Biol
, vol.7
, pp. 113-117
-
-
Li, M.1
-
25
-
-
35348998391
-
Structural basis for regulation of protein phosphatase 1 by inhibitor-2
-
Hurley, T. D. et al. Structural basis for regulation of protein phosphatase 1 by inhibitor-2. J. Biol. Chem. 282, 28874-28883 (2007).
-
(2007)
J. Biol. Chem
, vol.282
, pp. 28874-28883
-
-
Hurley, T.D.1
-
28
-
-
6344285318
-
Crystal structures of calpain-E64 and -leupeptin inhibitor complexes reveal mobile loops gating the active site
-
Moldoveanu, T., Campbell, R. L., Cuerrier, D. & Davies, P. L. Crystal structures of calpain-E64 and -leupeptin inhibitor complexes reveal mobile loops gating the active site. J. Mol. Biol. 343, 1313-1326 (2004).
-
(2004)
J. Mol. Biol
, vol.343
, pp. 1313-1326
-
-
Moldoveanu, T.1
Campbell, R.L.2
Cuerrier, D.3
Davies, P.L.4
-
29
-
-
33745933955
-
HKL-3000: The integration of data reduction and structure solution - from diffraction images to an initial model in minutes
-
Minor, W., Cymborowski, M., Otwinowski, Z. & Chruszcz, M. HKL-3000: The integration of data reduction and structure solution - from diffraction images to an initial model in minutes. Acta Crystallogr. D 62, 859-866 (2006).
-
(2006)
Acta Crystallogr. D
, vol.62
, pp. 859-866
-
-
Minor, W.1
Cymborowski, M.2
Otwinowski, Z.3
Chruszcz, M.4
-
30
-
-
0028103275
-
The CCP4 suite: Programs for protein crystallography
-
Collaborative Computational Project Number 4
-
Collaborative Computational Project Number 4. The CCP4 suite: Programs for protein crystallography. Acta Crystallogr. D 50, 760-763 (1994).
-
(1994)
Acta Crystallogr. D
, vol.50
, pp. 760-763
-
-
-
31
-
-
0035788107
-
Pushing the boundaries of molecular replacement with maximum likelihood
-
Read, R. J. Pushing the boundaries of molecular replacement with maximum likelihood. Acta Crystallogr. D 57, 1373-1382 (2001).
-
(2001)
Acta Crystallogr. D
, vol.57
, pp. 1373-1382
-
-
Read, R.J.1
-
32
-
-
3042613550
-
Likelihood-enhanced fast rotation functions
-
Storoni, L. C., McCoy, A. J. & Read, R. J. Likelihood-enhanced fast rotation functions. Acta Crystallogr. D 60, 432-438 (2004).
-
(2004)
Acta Crystallogr. D
, vol.60
, pp. 432-438
-
-
Storoni, L.C.1
McCoy, A.J.2
Read, R.J.3
-
33
-
-
0035182073
-
Use of TLS parameters to model anisotropic displacements in macromolecular refinement
-
Winn, M., Isupov, M. & Murshudov, G. N. Use of TLS parameters to model anisotropic displacements in macromolecular refinement. Acta Crystallogr. D 57, 122-133 (2001).
-
(2001)
Acta Crystallogr. D
, vol.57
, pp. 122-133
-
-
Winn, M.1
Isupov, M.2
Murshudov, G.N.3
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