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Volumn 88, Issue 3, 2010, Pages 353-368

Acrolein induces apoptosis through the death receptor pathway in A549 lung cells: Role of p53

Author keywords

A549 cell; Acrolein; Apoptosis; Caspase; Death receptor; Fas ligand; Oxidative stress; P53

Indexed keywords

ACROLEIN; ADAPTOR PROTEIN; ADENOSINE DIPHOSPHATE RIBOSE; CASPASE 2; CASPASE 7; CASPASE 8; CATALASE; DEATH RECEPTOR; FAS ANTIGEN; FAS LIGAND; MACROGOL; PHOSPHATIDYLSERINE; PIFITHRIN ALPHA; PROTEIN P53;

EID: 77950888687     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/Y09-134     Document Type: Article
Times cited : (33)

References (65)
  • 1
    • 77957187395 scopus 로고
    • The effects of inhalation of organic chemical air contaminants on murine lung host defenses
    • doi:10.1016/0272-0590(86)90184-3. PMID: 3519345
    • Aranyi, C., O'Shea, W.J., Graham, J.A., and Miller, F.J. 1986. The effects of inhalation of organic chemical air contaminants on murine lung host defenses. Fundam. Appl. Toxicol. 6(4): 713-720. doi:10.1016/0272-0590(86)90184- 3. PMID: 3519345.
    • (1986) Fundam. Appl. Toxicol. , vol.6 , Issue.4 , pp. 713-720
    • Aranyi, C.1    O'Shea, W.J.2    Graham, J.A.3    Miller, F.J.4
  • 2
    • 20344392399 scopus 로고    scopus 로고
    • Anti-tumoral effect of native and immobilized bovine serum amine oxidase in a mouse melanoma model
    • doi:10.1016/j.bcp. 2005.02.025 PMID: 15935145
    • Averill-Bates, D.A., Chérif, A., Agostinelli, E., Tanel, A., and For-tier, G. 2005. Anti-tumoral effect of native and immobilized bovine serum amine oxidase in a mouse melanoma model. Biochem. Pharmacol. 69(12): 1693-1704. doi:10.1016/j.bcp. 2005.02.025. PMID: 15935145.
    • (2005) Biochem. Pharmacol. , vol.69 , Issue.12 , pp. 1693-1704
    • Averill-Bates, D.A.1    Chérif, A.2    Agostinelli, E.3    Tanel, A.4    For-Tier, G.5
  • 4
    • 0041386256 scopus 로고    scopus 로고
    • Modulation of benzo[a]pyrene-induced p53 DNA activity by acrolein
    • DOI 10.1093/carcin/bgg061
    • Biswal, S., Maxwell, T., Rangasamy, T., and Kehrer, J.P. 2003. Modulation of benzo[a]pyrene-induced p53 DNA activity by ac-rolein. Carcinogenesis, 24(8): 1401-1406. doi:10.1093/carcin/bgg061. PMID: 12807757. (Pubitemid 37038829)
    • (2003) Carcinogenesis , vol.24 , Issue.8 , pp. 1401-1406
    • Biswal, S.1    Maxwell, T.2    Rangasamy, T.3    Kehrer, J.P.4
  • 5
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quanti-tation of microgram quantities of protein utilizing the principle of protein-dye binding
    • doi:10.1016/0003-2697(76)90527-3. PMID: 942051
    • Bradford, M.M. 1976. A rapid and sensitive method for the quanti-tation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72(1-2): 248-254. doi:10.1016/0003-2697(76)90527-3. PMID: 942051.
    • (1976) Anal. Biochem. , vol.72 , Issue.1-2 , pp. 248-254
    • Bradford, M.M.1
  • 6
    • 0028095477 scopus 로고
    • Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase
    • doi:10.1084/jem.180.4.1547. PMID: 7523573
    • Cifone, M.G., De Maria, R., Roncaioli, P., Rippo, M.R., Azuma, M., Lanier, L.L., et al. 1994. Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. J. Exp. Med. 180(4): 1547-1552. doi:10.1084/jem.180.4.1547. PMID: 7523573.
    • (1994) J. Exp. Med. , vol.180 , Issue.4 , pp. 1547-1552
    • Cifone, M.G.1    De Maria, R.2    Roncaioli, P.3    Rippo, M.R.4    Azuma, M.5    Lanier, L.L.6
  • 7
    • 0141853168 scopus 로고    scopus 로고
    • Live and let die: Regulatory mechanisms in Fas-mediated apoptosis
    • doi:10.1016/S0898-6568(03)00093-7. PMID: 14499341
    • Curtin, J.F., and Cotter, T.G. 2003. Live and let die: regulatory mechanisms in Fas-mediated apoptosis. Cell. Signal. 15(11): 983-992. doi:10.1016/S0898-6568(03)00093-7. PMID: 14499341.
    • (2003) Cell. Signal. , vol.15 , Issue.11 , pp. 983-992
    • Curtin, J.F.1    Cotter, T.G.2
  • 8
    • 0347601880 scopus 로고    scopus 로고
    • A decade of caspases
    • doi:10.1038/sj.onc.1207107. PMID: 14634618
    • Degterev, A., Boyce, M., and Yuan, J. 2003. A decade of caspases. Oncogene, 22(53): 8543-8567. doi:10.1038/sj.onc.1207107. PMID: 14634618.
    • (2003) Oncogene , vol.22 , Issue.53 , pp. 8543-8567
    • Degterev, A.1    Boyce, M.2    Yuan, J.3
  • 9
    • 6444245178 scopus 로고    scopus 로고
    • Oxidative stress induces the expression of Fas and Fas ligand and apoptosis in murine intestinal epithelial cells
    • doi:10.1016/S0891-5849(02) PMID: 12488132
    • Denning, T.L., Takaishi, H., Crowe, S.E., Boldogh, I., Jevnikar, A., and Ernst, P.B. 2002. Oxidative stress induces the expression of Fas and Fas ligand and apoptosis in murine intestinal epithelial cells. Free Radic. Biol. Med. 33(12): 1641-1650. doi:10.1016/S0891-5849(02)01141-1143 PMID: 12488132.
    • (2002) Free Radic. Biol. Med. , vol.33 , Issue.12 , pp. 1641-1650
    • Denning, T.L.1    Takaishi, H.2    Crowe, S.E.3    Boldogh, I.4    Jevnikar, A.5    Ernst, P.B.6
  • 10
    • 0028856840 scopus 로고
    • Dietary antioxidants and cigarette smoke-induced biomolecular damage: A complex interaction
    • PMID: 7495250
    • Eiserich, J.P., van der Vliet, A., Handelman, G.J., Halliwell, B., and Cross, C.E. 1995. Dietary antioxidants and cigarette smoke-induced biomolecular damage: a complex interaction. Am. J. Clin. Nutr. 62(6 Suppl): 1490S-1500S. PMID: 7495250.
    • (1995) Am. J. Clin. Nutr. , vol.62 , Issue.6 SUPPL.
    • Eiserich, J.P.1    Van Der Vliet, A.2    Handelman, G.J.3    Halliwell, B.4    Cross, C.E.5
  • 11
    • 33644812102 scopus 로고    scopus 로고
    • Caspase family proteases and apoptosis
    • doi:10.1111/j.1745-7270.2005. 00108.x PMID: 16270150
    • Fan, T.J., Han, L.H., Cong, R.S., and Liang, J. 2005. Caspase family proteases and apoptosis. Acta Biochim. Biophys. Sin. (Shanghai), 37(11): 719-727. doi:10.1111/j.1745-7270.2005. 00108.x. PMID: 16270150.
    • (2005) Acta Biochim. Biophys. Sin. (Shanghai) , vol.37 , Issue.11 , pp. 719-727
    • Fan, T.J.1    Han, L.H.2    Cong, R.S.3    Liang, J.4
  • 12
    • 33750282261 scopus 로고    scopus 로고
    • Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair
    • DOI 10.1073/pnas.0607031103
    • Feng, Z., Hu, W., Hu, Y., and Tang, M.S. 2006. Acrolein is a major cigarette-related lung cancer agent: preferential binding at p53 mutational hotspots and inhibition of DNA repair. Proc. Natl. Acad. Sci. U.S.A. 103(42): 15404-15409. doi:10.1073/pnas.0607031103. PMID: 17030796. (Pubitemid 44625604)
    • (2006) Proceedings of the National Academy of Sciences of the United States of America , vol.103 , Issue.42 , pp. 15404-15409
    • Feng, Z.1    Hu, W.2    Hu, Y.3    Tang, M.-S.4
  • 13
    • 33749178260 scopus 로고    scopus 로고
    • Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response
    • doi:10.1016/j. bbabio.2006.06.014 PMID: 16950166
    • Festjens, N., Vanden Berghe, T., and Vandenabeele, P. 2006. Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response. Biochim. Biophys. Acta, 1757(9-10): 1371-1387. doi:10.1016/j. bbabio.2006.06.014. PMID: 16950166.
    • (2006) Biochim. Biophys. Acta , vol.1757 , Issue.9-10 , pp. 1371-1387
    • Festjens, N.1    Vanden Berghe, T.2    Vandenabeele, P.3
  • 14
    • 2942588680 scopus 로고    scopus 로고
    • Development of immunomodulatory six base-length non-CpG motif oligonucleotides for cancer vaccination
    • doi:10.1016/j.vaccine.2003.11.072. PMID: 15193412
    • Filion, M.C., Filion, B., Roy, J., Ménard, S., Reader, S., and Phillips, N.C. 2004. Development of immunomodulatory six base-length non-CpG motif oligonucleotides for cancer vaccination. Vaccine, 22(19): 2480-2488. doi:10.1016/j.vaccine.2003.11.072. PMID: 15193412.
    • (2004) Vaccine , vol.22 , Issue.19 , pp. 2480-2488
    • Filion, M.C.1    Filion, B.2    Roy, J.3    Ménard, S.4    Reader, S.5    Phillips, N.C.6
  • 15
    • 0034835741 scopus 로고    scopus 로고
    • Inhibition of neutrophil apoptosis by acrolein: A mechanism of tobacco-related lung disease?
    • PMID: 11504702
    • Finkelstein, E.I., Nardini, M., and van der Vliet, A. 2001. Inhibition of neutrophil apoptosis by acrolein: a mechanism of tobacco-related lung disease? Am. J. Physiol. Lung Cell. Mol. Physiol. 281(3): L732-L739. PMID: 11504702.
    • (2001) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.281 , Issue.3
    • Finkelstein, E.I.1    Nardini, M.2    Van Der Vliet, A.3
  • 16
    • 0035976906 scopus 로고    scopus 로고
    • Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis
    • doi:10.1074/jbc.M104919200. PMID: 11581255
    • Gómez-Angelats, M., and Cidlowski, J.A. 2001. Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis. J. Biol. Chem. 276(48): 44944-44952. doi:10.1074/jbc.M104919200. PMID: 11581255.
    • (2001) J. Biol. Chem. , vol.276 , Issue.48 , pp. 44944-44952
    • Gómez-Angelats, M.1    Cidlowski, J.A.2
  • 17
    • 73449129394 scopus 로고    scopus 로고
    • Hydrogen peroxide as a cell-survival signaling molecule
    • doi:10.1089/ars.2009.2728. PMID: 19558209
    • Groeger, G., Quiney, C., and Cotter, T.G. 2009. Hydrogen peroxide as a cell-survival signaling molecule. Antioxid. Redox Signal. 11(11): 2655-2671. doi:10.1089/ars.2009.2728. PMID: 19558209.
    • (2009) Antioxid. Redox Signal. , vol.11 , Issue.11 , pp. 2655-2671
    • Groeger, G.1    Quiney, C.2    Cotter, T.G.3
  • 18
    • 33644503483 scopus 로고    scopus 로고
    • The death receptor family and the extrinsic pathway
    • Edited by X.-M. Yin and Z. Dong. Humana Press, Totowa, New Jersey
    • Guicciardi, M.E., and Gores, G.J. 2003. The death receptor family and the extrinsic pathway. In Essentials of apoptosis: a guide for basic and clinical research. Edited by X.-M. Yin and Z. Dong. Humana Press, Totowa, New Jersey. pp. 67-84.
    • (2003) Essentials of Apoptosis: A Guide for Basic and Clinical Research , pp. 67-84
    • Guicciardi, M.E.1    Gores, G.J.2
  • 19
    • 0037134495 scopus 로고    scopus 로고
    • Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria
    • doi:10.1074/jbc.M108029200. PMID: 11832478
    • Guo, Y., Srinivasula, S.M., Druilhe, A., Fernandes-Alnemri, T., and Alnemri, E.S. 2002. Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria. J. Biol. Chem. 277(16): 13430-13437. doi:10.1074/jbc.M108029200. PMID: 11832478.
    • (2002) J. Biol. Chem. , vol.277 , Issue.16 , pp. 13430-13437
    • Guo, Y.1    Srinivasula, S.M.2    Druilhe, A.3    Fernandes-Alnemri, T.4    Alnemri, E.S.5
  • 20
    • 0030865646 scopus 로고    scopus 로고
    • Dual regulation of caspase activity by hydrogen peroxide: Implications for apoptosis
    • doi:10.1016/S0014-5793(97)01068-5. PMID: 9323034
    • Hampton, M.B., and Orrenius, S. 1997. Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis. FEBS Lett. 414(3): 552-556. doi:10.1016/S0014-5793(97)01068-5. PMID: 9323034.
    • (1997) FEBS Lett. , vol.414 , Issue.3 , pp. 552-556
    • Hampton, M.B.1    Orrenius, S.2
  • 21
    • 16844381848 scopus 로고    scopus 로고
    • The extracellular domains of FasL and Fas are sufficient for the formation of supramolecular FasL-Fas clusters of high stability
    • doi:10.1083/jcb.200501048. PMID: 15795317
    • Henkler, F., Behrle, E., Dennehy, K.M., Wicovsky, A., Peters, N., Warnke, C., et al. 2005. The extracellular domains of FasL and Fas are sufficient for the formation of supramolecular FasL-Fas clusters of high stability. J. Cell Biol. 168(7): 1087-1098. doi:10.1083/jcb.200501048. PMID: 15795317.
    • (2005) J. Cell Biol. , vol.168 , Issue.7 , pp. 1087-1098
    • Henkler, F.1    Behrle, E.2    Dennehy, K.M.3    Wicovsky, A.4    Peters, N.5    Warnke, C.6
  • 22
    • 15944379869 scopus 로고    scopus 로고
    • Cas-pase-2 is resistant to inhibition by inhibitor of apoptosis proteins (IAPs) and can activate caspase-7
    • doi:10.1111/j.1742-4658.2005.04573.x. PMID: 15752357
    • Ho, P.K., Jabbour, A.M., Ekert, P.G., and Hawkins, C.J. 2005. Cas-pase-2 is resistant to inhibition by inhibitor of apoptosis proteins (IAPs) and can activate caspase-7. FEBS J. 272(6): 1401-1414. doi:10.1111/j.1742-4658.2005. 04573.x. PMID: 15752357.
    • (2005) FEBS J. , vol.272 , Issue.6 , pp. 1401-1414
    • Ho, P.K.1    Jabbour, A.M.2    Ekert, P.G.3    Hawkins, C.J.4
  • 23
    • 0035218753 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: An overview of pathology and pathogenesis
    • discussion 19-26 doi:10.1002/0470868678.ch2. PMID: 11199102
    • Hogg, J.C. 2001. Chronic obstructive pulmonary disease: an overview of pathology and pathogenesis. Novartis Found. Symp. 234: 4-19, discussion 19-26. doi:10.1002/0470868678.ch2. PMID: 11199102.
    • (2001) Novartis Found. Symp. , vol.234 , Issue.4-19
    • Hogg, J.C.1
  • 24
    • 5944233768 scopus 로고    scopus 로고
    • Fas triggers an alternative, caspase-8-inde-pendent cell death pathway using the kinase RIP as effector molecule
    • doi:10.1038/82732. PMID: 11101870
    • Holler, N., Zaru, R., Micheau, O., Thome, M., Attinger, A., Vali-tutti, S., et al. 2000. Fas triggers an alternative, caspase-8-inde-pendent cell death pathway using the kinase RIP as effector molecule. Nat. Immunol. 1(6): 489-495. doi:10.1038/82732. PMID: 11101870.
    • (2000) Nat. Immunol. , vol.1 , Issue.6 , pp. 489-495
    • Holler, N.1    Zaru, R.2    Micheau, O.3    Thome, M.4    Attinger, A.5    Vali-Tutti, S.6
  • 25
    • 0033515441 scopus 로고    scopus 로고
    • Acrolein causes inhibitor kappaB-independent decreases in nuclear factor kappaB activation in human lung ade-nocarcinoma (A549) cells
    • doi:10.1074/jbc.274.14.9200. PMID: 10092592
    • Horton, N.D., Biswal, S.S., Corrigan, L.L., Bratta, J., and Kehrer, J.P. 1999. Acrolein causes inhibitor kappaB-independent decreases in nuclear factor kappaB activation in human lung ade-nocarcinoma (A549) cells. J. Biol. Chem. 274(14): 9200-9206. doi:10.1074/jbc.274.14.9200. PMID: 10092592.
    • (1999) J. Biol. Chem. , vol.274 , Issue.14 , pp. 9200-9206
    • Horton, N.D.1    Biswal, S.S.2    Corrigan, L.L.3    Bratta, J.4    Kehrer, J.P.5
  • 26
    • 33846419151 scopus 로고    scopus 로고
    • GSH-dependent regulation of Fas-mediated caspase-8 activation by ac-rolein
    • doi:10.1016/j.febslet.2006. 12.040 PMID: 17222828
    • Hristova, M., Heuvelmans, S., and van der Vliet, A. 2007. GSH-dependent regulation of Fas-mediated caspase-8 activation by ac-rolein. FEBS Lett. 581(3): 361-367. doi:10.1016/j.febslet.2006. 12.040. PMID: 17222828.
    • (2007) FEBS Lett. , vol.581 , Issue.3 , pp. 361-367
    • Hristova, M.1    Heuvelmans, S.2    Van Der Vliet, A.3
  • 27
    • 67449085047 scopus 로고    scopus 로고
    • Level of reactive oxygen species induced by p21Waf1/CIP1 is critical for the determination of cell fate
    • doi:10.1111/j.1349-7006.2009. 01166.x PMID: 19432898
    • Inoue, T., Kato, K., Kato, H., Asanoma, K., Kuboyama, A., Ueoka, Y., et al. 2009. Level of reactive oxygen species induced by p21Waf1/CIP1 is critical for the determination of cell fate. Cancer Sci. 100(7): 1275-1283. doi:10.1111/j.1349-7006.2009. 01166.x. PMID: 19432898.
    • (2009) Cancer Sci. , vol.100 , Issue.7 , pp. 1275-1283
    • Inoue, T.1    Kato, K.2    Kato, H.3    Asanoma, K.4    Kuboyama, A.5    Ueoka, Y.6
  • 28
    • 33846068507 scopus 로고    scopus 로고
    • From caspases to alternative cell-death mechanisms
    • Edited by X.-M. Yin and Z. Dong. Humana Press, Totowa, New Jersey
    • Jäättelä, M., and Leist, M. 2003. From caspases to alternative cell-death mechanisms. In Essentials of apoptosis: a guide for basic and clinical research. Edited by X.-M. Yin and Z. Dong. Humana Press, Totowa, New Jersey. pp. 101-122.
    • (2003) Essentials of Apoptosis: A Guide for Basic and Clinical Research , pp. 101-122
    • Jäättelä, M.1    Leist, M.2
  • 29
    • 0028804857 scopus 로고
    • Metalloproteinase-mediated release of human Fas ligand
    • doi:10.1084/jem.182.6.1777 PMID: 7500022
    • Kayagaki, N., Kawasaki, A., Ebata, T., Ohmoto, H., Ikeda, S., In-oue, S., et al. 1995. Metalloproteinase-mediated release of human Fas ligand. J. Exp. Med. 182(6): 1777-1783. doi:10.1084/jem.182.6.1777. PMID: 7500022.
    • (1995) J. Exp. Med. , vol.182 , Issue.6 , pp. 1777-1783
    • Kayagaki, N.1    Kawasaki, A.2    Ebata, T.3    Ohmoto, H.4    Ikeda, S.5    In-Oue, S.6
  • 30
    • 0033864802 scopus 로고    scopus 로고
    • The molecular effects of acro-lein
    • doi:10.1093/toxsci/57.1.6. PMID: 10966506
    • Kehrer, J.P., and Biswal, S.S. 2000. The molecular effects of acro-lein. Toxicol. Sci. 57(1): 6-15. doi:10.1093/toxsci/57.1.6. PMID: 10966506.
    • (2000) Toxicol. Sci. , vol.57 , Issue.1 , pp. 6-15
    • Kehrer, J.P.1    Biswal, S.S.2
  • 31
    • 0037154352 scopus 로고    scopus 로고
    • Acrolein-induced cell death: A caspase-influenced decision between apoptosis and oncosis/ne-crosis
    • doi:10.1016/S0009-2797(01)00295-2. PMID: 11803030
    • Kern, J.C., and Kehrer, J.P. 2002. Acrolein-induced cell death: a caspase-influenced decision between apoptosis and oncosis/ne-crosis. Chem. Biol. Interact. 139(1): 79-95. doi:10.1016/S0009-2797(01)00295-2. PMID: 11803030.
    • (2002) Chem. Biol. Interact. , vol.139 , Issue.1 , pp. 79-95
    • Kern, J.C.1    Kehrer, J.P.2
  • 32
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • doi:10.1038/227680a0. PMID: 5432063
    • Laemmli, U.K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227(5259): 680-685. doi:10.1038/227680a0. PMID: 5432063.
    • (1970) Nature , vol.227 , Issue.5259 , pp. 680-685
    • Laemmli, U.K.1
  • 33
    • 0023697978 scopus 로고
    • Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis
    • PMID: 3171180
    • Laster, S.M., Wood, J.G., and Gooding, L.R. 1988. Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis. J. Immunol. 141(8): 2629-2634. PMID: 3171180.
    • (1988) J. Immunol. , vol.141 , Issue.8 , pp. 2629-2634
    • Laster, S.M.1    Wood, J.G.2    Gooding, L.R.3
  • 34
    • 33745932874 scopus 로고    scopus 로고
    • Cas-pase-2 is activated at the CD95 death-inducing signaling complex in the course of CD95-induced apoptosis
    • doi:10.1182/blood-2005-07-007096. PMID: 16822901
    • Lavrik, I.N., Golks, A., Baumann, S., and Krammer, P.H. 2006. Cas-pase-2 is activated at the CD95 death-inducing signaling complex in the course of CD95-induced apoptosis. Blood, 108(2): 559-565. doi:10.1182/blood-2005-07- 007096. PMID: 16822901.
    • (2006) Blood , vol.108 , Issue.2 , pp. 559-565
    • Lavrik, I.N.1    Golks, A.2    Baumann, S.3    Krammer, P.H.4
  • 35
    • 0031214090 scopus 로고    scopus 로고
    • Ac-rolein-induced cell death in human alveolar macrophages
    • doi:10.1006/taap.1997. 8189 PMID: 9266806
    • Li, L., Hamilton, R.F., Jr., Taylor, D.E., and Holian, A. 1997. Ac-rolein-induced cell death in human alveolar macrophages. Toxi-col. Appl. Pharmacol. 145(2): 331-339. doi:10.1006/taap.1997. 8189. PMID: 9266806.
    • (1997) Toxi-col. Appl. Pharmacol. , vol.145 , Issue.2 , pp. 331-339
    • Li, L.1    Hamilton Jr., R.F.2    Taylor, D.E.3    Holian, A.4
  • 36
    • 0035112495 scopus 로고    scopus 로고
    • Acrolein is increased in Alzheimer's disease brain and is toxic to primary hip-pocampal cultures
    • doi:10. 1016/S0197-4580(00) PMID: 11182468
    • Lovell, M.A., Xie, C., and Markesbery, W.R. 2001. Acrolein is increased in Alzheimer's disease brain and is toxic to primary hip-pocampal cultures. Neurobiol. Aging, 22(2): 187-194. doi:10. 1016/S0197-4580(00)00235-239 PMID: 11182468.
    • (2001) Neurobiol. Aging , vol.22 , Issue.2 , pp. 187-194
    • Lovell, M.A.1    Xie, C.2    Markesbery, W.R.3
  • 37
    • 24644490031 scopus 로고    scopus 로고
    • Acrolein-induced cell death in PC12 cells: Role of mitochondria-mediated oxidative stress
    • doi:10.1016/j.neuint. 2005.07.002 PMID: 16140421
    • Luo, J., Robinson, J.P., and Shi, R. 2005. Acrolein-induced cell death in PC12 cells: role of mitochondria-mediated oxidative stress. Neurochem. Int. 47(7): 449-457. doi:10.1016/j.neuint. 2005.07.002. PMID: 16140421.
    • (2005) Neurochem. Int. , vol.47 , Issue.7 , pp. 449-457
    • Luo, J.1    Robinson, J.P.2    Shi, R.3
  • 38
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • doi:10. 1038/nrm2239 PMID: 17717517
    • Maiuri, M.C., Zalckvar, E., Kimchi, A., and Kroemer, G. 2007. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat. Rev. Mol. Cell Biol. 8(9): 741-752. doi:10. 1038/nrm2239. PMID: 17717517.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , Issue.9 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 39
    • 33644524120 scopus 로고    scopus 로고
    • Apoptosis and necrosis in the liver: A tale of two deaths?
    • doi:10.1002/hep.21062. PMID: 16447272
    • Malhi, H., Gores, G.J., and Lemasters, J.J. 2006. Apoptosis and necrosis in the liver: A tale of two deaths? Hepatology, 43(2 Suppl 1): S31-S44. doi:10.1002/hep.21062. PMID: 16447272.
    • (2006) Hepatology , vol.43 , Issue.2 SUPPL. 1
    • Malhi, H.1    Gores, G.J.2    Lemasters, J.J.3
  • 40
    • 33748536416 scopus 로고    scopus 로고
    • Apoptosis mediated by p53 in rat neural AF5 cells following treatment with hydrogen peroxide and staurosporine
    • doi:10.1016/j.brainres. 2006.07.024 PMID: 16901471
    • McNeill-Blue, C., Wetmore, B.A., Sanchez, J.F., Freed, W.J., and Merrick, B.A. 2006. Apoptosis mediated by p53 in rat neural AF5 cells following treatment with hydrogen peroxide and staurosporine. Brain Res. 1112(1): 1-15. doi:10.1016/j.brainres. 2006.07.024. PMID: 16901471.
    • (2006) Brain Res. , vol.1112 , Issue.1 , pp. 1-15
    • McNeill-Blue, C.1    Wetmore, B.A.2    Sanchez, J.F.3    Freed, W.J.4    Merrick, B.A.5
  • 41
    • 0347039482 scopus 로고    scopus 로고
    • Tumor suppressor gene p53: Mechanisms of action in cell proliferation and death
    • PMID: 11496714
    • Mendoza-Rodŕiguez, C.A., and Cerbón, M.A. 2001.[Tumor suppressor gene p53: mechanisms of action in cell proliferation and death]. Rev. Invest. Clin. 53(3): 266-273. PMID: 11496714.
    • (2001) Rev. Invest. Clin. , vol.53 , Issue.3 , pp. 266-273
    • Mendoza-Rodŕiguez, C.A.1    Cerbón, M.A.2
  • 42
    • 33745254719 scopus 로고    scopus 로고
    • Fas/CD95 death receptor and lipid rafts: New targets for apoptosis-directed cancer therapy
    • doi:10.1016/j.drup.2006.04. 002 PMID: 16687251
    • Mollinedo, F., and Gajate, C. 2006. Fas/CD95 death receptor and lipid rafts: new targets for apoptosis-directed cancer therapy. Drug Resist. Updat. 9(1-2): 51-73. doi:10.1016/j.drup.2006.04. 002. PMID: 16687251.
    • (2006) Drug Resist. Updat. , vol.9 , Issue.1-2 , pp. 51-73
    • Mollinedo, F.1    Gajate, C.2
  • 43
    • 0037168998 scopus 로고    scopus 로고
    • Acrolein-induced cyto-toxicity in cultured human bronchial epithelial cells. Modulation by alpha-tocopherol and ascorbic acid
    • doi:10.1016/S0300-483X(01)00540-6. PMID: 11788155
    • Nardini, M., Finkelstein, E.I., Reddy, S., Valacchi, G., Traber, M., Cross, C.E., and van der Vliet, A. 2002. Acrolein-induced cyto-toxicity in cultured human bronchial epithelial cells. Modulation by alpha-tocopherol and ascorbic acid. Toxicology, 170(3): 173-185. doi:10.1016/S0300-483X(01)00540-6. PMID: 11788155.
    • (2002) Toxicology , vol.170 , Issue.3 , pp. 173-185
    • Nardini, M.1    Finkelstein, E.I.2    Reddy, S.3    Valacchi, G.4    Traber, M.5    Cross, C.E.6    Van Der Vliet, A.7
  • 44
    • 33845762723 scopus 로고    scopus 로고
    • Caspase-8 dependent TRAIL-induced apoptosis in cancer cell lines is inhibited by vitamin C and catalase
    • doi:10.1007/s10495-006-0475-0. PMID: 17031493
    • Perez-Cruz, I., Cárcamo, J.M., and Golde, D.W. 2007. Caspase-8 dependent TRAIL-induced apoptosis in cancer cell lines is inhibited by vitamin C and catalase. Apoptosis, 12(1): 225-234. doi:10.1007/s10495-006-0475-0. PMID: 17031493.
    • (2007) Apoptosis , vol.12 , Issue.1 , pp. 225-234
    • Perez-Cruz, I.1    Cárcamo, J.M.2    Golde, D.W.3
  • 45
    • 0032945381 scopus 로고    scopus 로고
    • Acrolein cytotoxicity and glu-tathione depletion in n-3 fatty acid sensitive-and resistant human tumor cells
    • PMID: 10226583
    • Rudra, P.K., and Krokan, H.E. 1999. Acrolein cytotoxicity and glu-tathione depletion in n-3 fatty acid sensitive-and resistant human tumor cells. Anticancer Res. 19(1A): 461-469. PMID: 10226583.
    • (1999) Anticancer Res. , vol.19 , Issue.1 A , pp. 461-469
    • Rudra, P.K.1    Krokan, H.E.2
  • 46
    • 0032748727 scopus 로고    scopus 로고
    • Airway inflammation in chronic obstructive pulmonary disease
    • PMID: 10556163
    • Saetta, M. 1999. Airway inflammation in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 160(5 Pt 2): S17-S20. PMID: 10556163.
    • (1999) Am. J. Respir. Crit. Care Med. , vol.160 , Issue.5 PART 2
    • Saetta, M.1
  • 47
    • 0033561295 scopus 로고    scopus 로고
    • Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells
    • doi:10.1093/emboj/18.8.2040. PMID: 10205158
    • Samali, A., Cai, J., Zhivotovsky, B., Jones, D.P., and Orrenius, S. 1999. Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells. EMBO J. 18(8): 2040-2048. doi:10.1093/emboj/18.8.2040. PMID: 10205158.
    • (1999) EMBO J. , vol.18 , Issue.8 , pp. 2040-2048
    • Samali, A.1    Cai, J.2    Zhivotovsky, B.3    Jones, D.P.4    Orrenius, S.5
  • 48
    • 0028360901 scopus 로고
    • The role of airway mucus in pulmonary toxicology
    • doi:10.2307/3431824. PMID: 7925190
    • Samet, J.M., and Cheng, P.W. 1994. The role of airway mucus in pulmonary toxicology. Environ. Health Perspect. 102(Suppl 2): 89-103. doi:10.2307/3431824. PMID: 7925190.
    • (1994) Environ. Health Perspect. , vol.102 , Issue.SUPPL. 2 , pp. 89-103
    • Samet, J.M.1    Cheng, P.W.2
  • 49
    • 0033151677 scopus 로고    scopus 로고
    • A 1-hour enzyme-linked immunosorbent assay for quantitation of acrolein-and hydroxynonenal-modified proteins by epitope-bound casein matrix method
    • doi:10.1006/abio.1999.4073. PMID: 10334850
    • Satoh, K., Yamada, S., Koike, Y., Igarashi, Y., Toyokuni, S., Ku-mano, T., et al. 1999. A 1-hour enzyme-linked immunosorbent assay for quantitation of acrolein-and hydroxynonenal-modified proteins by epitope-bound casein matrix method. Anal. Bio-chem. 270(2): 323-328. doi:10.1006/abio.1999.4073. PMID: 10334850.
    • (1999) Anal. Bio-chem. , vol.270 , Issue.2 , pp. 323-328
    • Satoh, K.1    Yamada, S.2    Koike, Y.3    Igarashi, Y.4    Toyokuni, S.5    Ku-Mano, T.6
  • 50
    • 85006263913 scopus 로고    scopus 로고
    • BID regulation by p53 contributes to chemosensitivity
    • DOI 10.1038/ncb866
    • Sax, J.K., Fei, P., Murphy, M.E., Bernhard, E., Korsmeyer, S.J., and El-Deiry, W.S. 2002. BID regulation by p53 contributes to chemosensitivity. Nat. Cell Biol. 4(11): 842-849. doi:10.1038/ncb866. PMID: 12402042. (Pubitemid 35331358)
    • (2002) Nature Cell Biology , vol.4 , Issue.11 , pp. 842-849
    • Sax, J.K.1    Fei, P.2    Murphy, M.E.3    Bernhard, E.4    Korsmeyer, S.J.5    El-Deiry, W.S.6
  • 51
    • 38949113159 scopus 로고    scopus 로고
    • Acrolein: Sources, metabolism, and biomolecular interactions relevant to human health and disease
    • doi:10.1002/mnfr. 200700412 PMID: 18203133
    • Stevens, J.F., and Maier, C.S. 2008. Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease. Mol. Nutr. Food Res. 52(1): 7-25. doi:10.1002/mnfr. 200700412. PMID: 18203133.
    • (2008) Mol. Nutr. Food Res. , vol.52 , Issue.1 , pp. 7-25
    • Stevens, J.F.1    Maier, C.S.2
  • 52
    • 17444421537 scopus 로고    scopus 로고
    • The aldehyde acrolein induces apoptosis via activation of the mitochondrial pathway
    • doi:10.1016/j. bbamcr.2004.11.007 PMID: 15843039
    • Tanel, A., and Averill-Bates, D.A. 2005. The aldehyde acrolein induces apoptosis via activation of the mitochondrial pathway. Biochim. Biophys. Acta, 1743(3): 255-267. doi:10.1016/j. bbamcr.2004.11.007. PMID: 15843039.
    • (2005) Biochim. Biophys. Acta , vol.1743 , Issue.3 , pp. 255-267
    • Tanel, A.1    Averill-Bates, D.A.2
  • 53
    • 33847291268 scopus 로고    scopus 로고
    • Activation of the death receptor pathway of apoptosis by the aldehyde acrolein
    • doi:10.1016/j.freeradbiomed. 2006.12.009 PMID: 17320762
    • Tanel, A., and Averill-Bates, D.A. 2007a. Activation of the death receptor pathway of apoptosis by the aldehyde acrolein. Free Radic. Biol. Med. 42(6): 798-810. doi:10.1016/j.freeradbiomed. 2006.12.009. PMID: 17320762.
    • (2007) Free Radic. Biol. Med. , vol.42 , Issue.6 , pp. 798-810
    • Tanel, A.1    Averill-Bates, D.A.2
  • 54
    • 33947373035 scopus 로고    scopus 로고
    • P38 and ERK mitogen-activated protein kinases mediate acrolein-induced apoptosis in Chinese hamster ovary cells
    • doi:10.1016/j.cellsig.2006.10.014. PMID: 17196791
    • Tanel, A., and Averill-Bates, D.A. 2007b. P38 and ERK mitogen-activated protein kinases mediate acrolein-induced apoptosis in Chinese hamster ovary cells. Cell. Signal. 19(5): 968-977. doi:10.1016/j.cellsig.2006.10.014. PMID: 17196791.
    • (2007) Cell. Signal. , vol.19 , Issue.5 , pp. 968-977
    • Tanel, A.1    Averill-Bates, D.A.2
  • 55
    • 41949116699 scopus 로고    scopus 로고
    • Protein alkylation, tran-scriptional responses and cytochrome c release during acrolein toxicity in A549 cells: Influence of nucleophilic culture media constituents
    • doi:10.1016/j. tiv.2007.12.018 PMID: 18282682
    • Thompson, C.A., and Burcham, P.C. 2008. Protein alkylation, tran-scriptional responses and cytochrome c release during acrolein toxicity in A549 cells: influence of nucleophilic culture media constituents. Toxicol. In Vitro, 22(4): 844-853. doi:10.1016/j. tiv.2007.12.018. PMID: 18282682.
    • (2008) Toxicol in Vitro , vol.22 , Issue.4 , pp. 844-853
    • Thompson, C.A.1    Burcham, P.C.2
  • 56
    • 33846219997 scopus 로고    scopus 로고
    • Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway
    • doi:10.1038/sj.emboj. 7601473 PMID: 17159900
    • Tinel, A., Janssens, S., Lippens, S., Cuenin, S., Logette, E., Jac-card, B., et al. 2007. Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway. EMBO J. 26(1): 197-208. doi:10.1038/sj.emboj. 7601473. PMID: 17159900.
    • (2007) EMBO J. , vol.26 , Issue.1 , pp. 197-208
    • Tinel, A.1    Janssens, S.2    Lippens, S.3    Cuenin, S.4    Logette, E.5    Jac-Card, B.6
  • 57
    • 0036143302 scopus 로고    scopus 로고
    • A fatal human intoxication with the herbicide allyl alcohol (2-propen-1-ol)
    • PMID: 11888018
    • Toennes, S.W., Schmidt, K., Fandiño, A.S., and Kauert, G.F. 2002. A fatal human intoxication with the herbicide allyl alcohol (2-propen-1-ol). J. Anal. Toxicol. 26(1): 55-57. PMID: 11888018
    • (2002) J. Anal. Toxicol. , vol.26 , Issue.1 , pp. 55-57
    • Toennes, S.W.1    Schmidt, K.2    Fandiño, A.S.3    Kauert, G.F.4
  • 58
    • 34548573465 scopus 로고    scopus 로고
    • USEPA. US Environmental Protection Agency, Washington, DC
    • USEPA. 2003. Toxicological review of acrolein. US Environmental Protection Agency, Washington, DC.
    • (2003) Toxicological Review of Acrolein
  • 59
    • 0031985647 scopus 로고    scopus 로고
    • Annexin V-affinity assay: A review on an apoptosis detection system based on phosphatidylserine exposure
    • doi:10.1002/(SICI)1097-0320(19980101) 31: 1 1:AID-CYTO13.0.CO;2-R PMID: 9450519
    • van Engeland, M., Nieland, L.J., Ramaekers, F.C., Schutte, B., and Re-utelingsperger, C.P. 1998. Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry, 31(1): 1-9. doi:10.1002/(SICI)1097-0320(19980101) 31:13.0.CO;2-R. PMID: 9450519.
    • (1998) Cytometry , vol.31 , Issue.1 , pp. 1-9
    • Van Engeland, M.1    Nieland, L.J.2    Ramaekers, F.C.3    Schutte, B.4    Re-Utelingsperger, C.P.5
  • 60
    • 34249847071 scopus 로고    scopus 로고
    • Enhanced EGFP-chromophore-assisted laser inactivation using deficient cells rescued with functional EGFP-fusion proteins
    • doi:10. 1073/pnas.0701801104 PMID: 17420475
    • Vitriol, E.A., Uetrecht, A.C., Shen, F., Jacobson, K., and Bear, J.E. 2007. Enhanced EGFP-chromophore-assisted laser inactivation using deficient cells rescued with functional EGFP-fusion proteins. Proc. Natl. Acad. Sci. U.S.A. 104(16): 6702-6707. doi:10. 1073/pnas.0701801104. PMID: 17420475.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , Issue.16 , pp. 6702-6707
    • Vitriol, E.A.1    Uetrecht, A.C.2    Shen, F.3    Jacobson, K.4    Bear, J.E.5
  • 61
    • 49149130029 scopus 로고    scopus 로고
    • The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation
    • PMID: 18292530
    • Wang, L., Azad, N., Kongkaneramit, L., Chen, F., Lu, Y., Jiang, B.H., and Rojanasakul, Y. 2008. The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation. J. Immunol. 180(5): 3072-3080. PMID: 18292530.
    • (2008) J. Immunol. , vol.180 , Issue.5 , pp. 3072-3080
    • Wang, L.1    Azad, N.2    Kongkaneramit, L.3    Chen, F.4    Lu, Y.5    Jiang, B.H.6    Rojanasakul, Y.7
  • 63
    • 0030998159 scopus 로고    scopus 로고
    • The toxicology of environmental tobacco smoke
    • doi:10.1146/annurev.pharmtox.37.1.29. PMID: 9131245
    • Witschi, H., Joad, J.P., and Pinkerton, K.E. 1997. The toxicology of environmental tobacco smoke. Annu. Rev. Pharmacol. Toxicol. 37(1): 29-52. doi:10.1146/annurev.pharmtox.37.1.29. PMID: 9131245.
    • (1997) Annu. Rev. Pharmacol. Toxicol. , vol.37 , Issue.1 , pp. 29-52
    • Witschi, H.1    Joad, J.P.2    Pinkerton, K.E.3
  • 64
    • 0037737758 scopus 로고    scopus 로고
    • Regulation of p53 responses by post-translational modifications
    • DOI 10.1038/sj.cdd.4401182
    • Xu, Y. 2003. Regulation of p53 responses by post-translational modifications. Cell Death Differ. 10(4): 400-403. doi:10.1038/sj.cdd.4401182. PMID: 12719715. (Pubitemid 36626351)
    • (2003) Cell Death and Differentiation , vol.10 , Issue.4 , pp. 400-403
    • Xu, Y.1
  • 65
    • 4544233514 scopus 로고    scopus 로고
    • Effect of acrolein and glutathione depleting agents on thiore-doxin
    • doi:10.1016/j.tox.2004. 06.056 PMID: 15388247
    • Yang, X., Wu, X., Choi, Y.E., Kern, J.C., and Kehrer, J.P. 2004. Effect of acrolein and glutathione depleting agents on thiore-doxin. Toxicology, 204(2-3): 209-218. doi:10.1016/j.tox.2004. 06.056. PMID: 15388247.
    • (2004) Toxicology , vol.204 , Issue.2-3 , pp. 209-218
    • Yang, X.1    Wu, X.2    Choi, Y.E.3    Kern, J.C.4    Kehrer, J.P.5


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