Acrolein activates matrix metalloproteinases by increasing reactive oxygen species in macrophages

Toxicology and Applied Pharmacology

Volumn 236, Issue 2, 2009, Pages 194-201

  O'Toole, Timothy E ^a   Zheng, Yu Ting ^a   Hellmann, Jason ^a   Conklin, Daniel J ^a   Barski, Oleg ^a   Bhatnagar, Aruni ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Acrolein; apoE null mouse; Atherosclerosis; Matrix metalloproteinase; Plaque destabilization; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; ACROLEIN; ALLOPURINOL; APOCYNIN; APOLIPOPROTEIN E; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GELATINASE B; OXIPURINOL; REACTIVE OXYGEN METABOLITE; ROTENONE; TIRON; XANTHINE OXIDASE;

ANIMAL TISSUE; ARTICLE; ATHEROSCLEROTIC PLAQUE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME RELEASE; EX VIVO STUDY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MACROPHAGE; MOUSE; NONHUMAN;

ACROLEIN; ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CALCIUM; CELL LINE; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION REGULATION; MACROPHAGES; MATRIX METALLOPROTEINASES; MICE; MICE, KNOCKOUT; REACTIVE OXYGEN SPECIES; XANTHINE OXIDASE;

MUS;

EID: 62549138221     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.01.024     Document Type: Article

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