메뉴 건너뛰기




Volumn 55, Issue 9, 2011, Pages 1291-1300

Acrolein induced DNA damage, mutagenicity and effect on DNA repair

Author keywords

Acrolein; DNA damage; Lung cancer; Mutation; Repair

Indexed keywords

ACROLEIN; CARCINOGEN; PROTEIN P53;

EID: 80052605887     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201100148     Document Type: Review
Times cited : (100)

References (41)
  • 1
    • 38949113159 scopus 로고    scopus 로고
    • Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease
    • Stevens, J. F., Maier, C. S., Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease. Mol. Nutr. Food Res. 2008, 52, 7-25.
    • (2008) Mol. Nutr. Food Res. , vol.52 , pp. 7-25
    • Stevens, J.F.1    Maier, C.S.2
  • 2
    • 0029824077 scopus 로고    scopus 로고
    • Lipid peroxidation as a potential endogenous source for the formation of exocyclic DNA adducts
    • Chung, F. L., Chen, H. J., Nath, R. G., Lipid peroxidation as a potential endogenous source for the formation of exocyclic DNA adducts. Carcinogenesis 1996, 17, 2105-2111.
    • (1996) Carcinogenesis , vol.17 , pp. 2105-2111
    • Chung, F.L.1    Chen, H.J.2    Nath, R.G.3
  • 3
    • 80052602103 scopus 로고    scopus 로고
    • Concise International Chemical Assessment Document, No. 43 (World health Organization)
    • Comes R, M. M., Eggleton M, Concise International Chemical Assessment Document, No. 43 (World health Organization), 2002.
    • (2002)
    • Comes, R.M.M.1    Eggleton, M.2
  • 4
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer, H., Schaur, R. J., Zollner, H., Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 1991, 11, 81-128.
    • (1991) Free Radic. Biol. Med. , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 5
    • 67649933847 scopus 로고    scopus 로고
    • Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha, beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal
    • Minko, I. G., Kozekov, I. D., Harris, T. M., Rizzo, C. J., et al., Chemistry and biology of DNA containing 1, N(2)-deoxyguanosine adducts of the alpha, beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal. Chem. Res. Toxicol. 2009, 22, 759-778.
    • (2009) Chem. Res. Toxicol. , vol.22 , pp. 759-778
    • Minko, I.G.1    Kozekov, I.D.2    Harris, T.M.3    Rizzo, C.J.4
  • 6
    • 0021319465 scopus 로고
    • Formation of cyclic 1,N2-propanodeoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde
    • Chung, F. L., Young, R., Hecht, S. S., Formation of cyclic 1, N2-propanodeoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde. Cancer Res. 1984, 44, 990-995.
    • (1984) Cancer Res. , vol.44 , pp. 990-995
    • Chung, F.L.1    Young, R.2    Hecht, S.S.3
  • 7
    • 33244473082 scopus 로고    scopus 로고
    • Determination of toxic carbonyl compounds in cigarette smoke
    • Fujioka, K., Shibamoto, T., Determination of toxic carbonyl compounds in cigarette smoke. Environ. Toxicol. 2006, 21, 47-54.
    • (2006) Environ. Toxicol. , vol.21 , pp. 47-54
    • Fujioka, K.1    Shibamoto, T.2
  • 8
    • 36849019121 scopus 로고    scopus 로고
    • Mechanisms of acrolein-induced myocardial dysfunction: implications for environmental and endogenous aldehyde exposure
    • Luo, J., Hill, B. G., Gu, Y., Cai, J., et al., Mechanisms of acrolein-induced myocardial dysfunction: implications for environmental and endogenous aldehyde exposure. Am. J. Physiol. Heart Circ. Physiol. 2007, 293, H3673-H3684.
    • (2007) Am. J. Physiol. Heart Circ. Physiol. , vol.293
    • Luo, J.1    Hill, B.G.2    Gu, Y.3    Cai, J.4
  • 9
    • 33750282261 scopus 로고    scopus 로고
    • Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair
    • Feng, Z., Hu, W., Hu, Y., Tang, M. S., Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair. Proc. Natl. Acad. Sci. USA 2006, 103, 15404-15409.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 15404-15409
    • Feng, Z.1    Hu, W.2    Hu, Y.3    Tang, M.S.4
  • 10
    • 34248524522 scopus 로고    scopus 로고
    • Detection and quantitation of acrolein-derived 1,N2-propanodeoxyguanosine adducts in human lung by liquid chromatography-electrospray ionization-tandem mass spectrometry
    • Zhang, S., Villalta, P. W., Wang, M., Hecht, S. S., Detection and quantitation of acrolein-derived 1, N2-propanodeoxyguanosine adducts in human lung by liquid chromatography-electrospray ionization-tandem mass spectrometry. Chem. Res. Toxicol. 2007, 20, 565-571.
    • (2007) Chem. Res. Toxicol. , vol.20 , pp. 565-571
    • Zhang, S.1    Villalta, P.W.2    Wang, M.3    Hecht, S.S.4
  • 11
    • 65949095199 scopus 로고    scopus 로고
    • Mutagenicity and sequence specificity of acrolein-DNA adducts
    • Wang, H. T., Zhang, S., Hu, Y., Tang, M. S., Mutagenicity and sequence specificity of acrolein-DNA adducts. Chem. Res. Toxicol. 2009, 22, 511-517.
    • (2009) Chem. Res. Toxicol. , vol.22 , pp. 511-517
    • Wang, H.T.1    Zhang, S.2    Hu, Y.3    Tang, M.S.4
  • 12
    • 0033153762 scopus 로고    scopus 로고
    • Role of O6-alkylguanine-DNA alkyltransferase in protecting against cyclophosphamide-induced toxicity and mutagenicity
    • Cai, Y., Wu, M. H., Ludeman, S. M., Grdina, D. J., Dolan, M. E., Role of O6-alkylguanine-DNA alkyltransferase in protecting against cyclophosphamide-induced toxicity and mutagenicity. Cancer Res. 1999, 59, 3059-3063.
    • (1999) Cancer Res. , vol.59 , pp. 3059-3063
    • Cai, Y.1    Wu, M.H.2    Ludeman, S.M.3    Grdina, D.J.4    Dolan, M.E.5
  • 13
    • 0034287446 scopus 로고    scopus 로고
    • Effect of O6-benzylguanine on alkylating agent-induced toxicity and mutagenicity. In Chinese hamster ovary cells expressing wild-type and mutant O6-alkylguanine-DNA alkyltransferases
    • Cai, Y., Wu, M. H., Xu-Welliver, M., Pegg, A. E., Effect of O6-benzylguanine on alkylating agent-induced toxicity and mutagenicity. In Chinese hamster ovary cells expressing wild-type and mutant O6-alkylguanine-DNA alkyltransferases. Cancer Res. 2000, 60, 5464-5469.
    • (2000) Cancer Res. , vol.60 , pp. 5464-5469
    • Cai, Y.1    Wu, M.H.2    Xu-Welliver, M.3    Pegg, A.E.4
  • 14
    • 34447342240 scopus 로고    scopus 로고
    • Role of MGMT in protecting against cyclophosphamide-induced toxicity in cells and animals
    • Hansen, R. J., Ludeman, S. M., Paikoff, S. J., Pegg, A. E., Dolan, M. E., Role of MGMT in protecting against cyclophosphamide-induced toxicity in cells and animals. DNA Repair 2007, 6, 1145-1154.
    • (2007) DNA Repair , vol.6 , pp. 1145-1154
    • Hansen, R.J.1    Ludeman, S.M.2    Paikoff, S.J.3    Pegg, A.E.4    Dolan, M.E.5
  • 15
    • 33947412631 scopus 로고    scopus 로고
    • Inhibition of acrolein-induced apoptosis by the antioxidant N-acetylcysteine
    • Tanel, A., Averill-Bates, D. A., Inhibition of acrolein-induced apoptosis by the antioxidant N-acetylcysteine. J. Pharmacol. Exp. Ther. 2007, 321, 73-83.
    • (2007) J. Pharmacol. Exp. Ther. , vol.321 , pp. 73-83
    • Tanel, A.1    Averill-Bates, D.A.2
  • 16
    • 39049192115 scopus 로고    scopus 로고
    • NTP Technical Report on the comparative toxicity studies of allyl acetate (CAS No. 591-87-7), allyl alcohol (CAS No. 107-18-6) and acrolein (CAS No. 107-02-8) administered by gavage to F344/N rats and B6C3F1 mice
    • Irwin, R. D., NTP Technical Report on the comparative toxicity studies of allyl acetate (CAS No. 591-87-7), allyl alcohol (CAS No. 107-18-6) and acrolein (CAS No. 107-02-8) administered by gavage to F344/N rats and B6C3F1 mice. Toxic Rep. Ser. 2006, 1-73, A71-H10.
    • (2006) Toxic Rep. Ser. , vol.1-73
    • Irwin, R.D.1
  • 17
    • 67650739174 scopus 로고    scopus 로고
    • Protective effect of lipoic acid against acrolein-induced cytotoxicity in IMR-90 human fibroblasts
    • Jia, L., Zhang, Z., Zhai, L., Bai, Y., Protective effect of lipoic acid against acrolein-induced cytotoxicity in IMR-90 human fibroblasts. J. Nutr. Sci. Vitaminol. 2009, 55, 126-130.
    • (2009) J. Nutr. Sci. Vitaminol. , vol.55 , pp. 126-130
    • Jia, L.1    Zhang, Z.2    Zhai, L.3    Bai, Y.4
  • 19
    • 37549053570 scopus 로고    scopus 로고
    • Lack of mutagenicity of acrolein-induced DNA adducts in mouse and human cells
    • Kim, S. I., Pfeifer, G. P., Besaratinia, A., Lack of mutagenicity of acrolein-induced DNA adducts in mouse and human cells. Cancer Res. 2007, 67, 11640-11647.
    • (2007) Cancer Res. , vol.67 , pp. 11640-11647
    • Kim, S.I.1    Pfeifer, G.P.2    Besaratinia, A.3
  • 20
    • 77950888687 scopus 로고    scopus 로고
    • Acrolein induces apoptosis through the death receptor pathway in A549 lung cells: role of p53
    • Roy, J., Pallepati, P., Bettaieb, A., Averill-Bates, D. A., Acrolein induces apoptosis through the death receptor pathway in A549 lung cells: role of p53. Can. J. Physiol. Pharmacol. 2010, 88, 353-368.
    • (2010) Can. J. Physiol. Pharmacol. , vol.88 , pp. 353-368
    • Roy, J.1    Pallepati, P.2    Bettaieb, A.3    Averill-Bates, D.A.4
  • 21
    • 0037154352 scopus 로고    scopus 로고
    • Acrolein-induced cell death: a caspase-influenced decision between apoptosis and oncosis/necrosis
    • Kern, J. C., Kehrer, J. P., Acrolein-induced cell death: a caspase-influenced decision between apoptosis and oncosis/necrosis. Chem. Biol. Interact. 2002, 139, 79-95.
    • (2002) Chem. Biol. Interact. , vol.139 , pp. 79-95
    • Kern, J.C.1    Kehrer, J.P.2
  • 22
    • 24644490031 scopus 로고    scopus 로고
    • Acrolein-induced cell death in PC12 cells: role of mitochondria-mediated oxidative stress
    • Luo, J., Robinson, J. P., Shi, R., Acrolein-induced cell death in PC12 cells: role of mitochondria-mediated oxidative stress. Neurochem. Int. 2005, 47, 449-457.
    • (2005) Neurochem. Int. , vol.47 , pp. 449-457
    • Luo, J.1    Robinson, J.P.2    Shi, R.3
  • 23
    • 17444421537 scopus 로고    scopus 로고
    • The aldehyde acrolein induces apoptosis via activation of the mitochondrial pathway
    • Tanel, A., Averill-Bates, D. A., The aldehyde acrolein induces apoptosis via activation of the mitochondrial pathway. Biochim. Biophys. Acta 2005, 1743, 255-267.
    • (2005) Biochim. Biophys. Acta , pp. 255-267
    • Tanel, A.1    Averill-Bates, D.A.2
  • 24
    • 33745132417 scopus 로고    scopus 로고
    • Acrolein is a mitochondrial toxin: effects on respiratory function and enzyme activities in isolated rat liver mitochondria
    • Sun, L., Luo, C., Long, J., Wei, D., Liu, J., Acrolein is a mitochondrial toxin: effects on respiratory function and enzyme activities in isolated rat liver mitochondria. Mitochondrion 2006, 6, 136-142.
    • (2006) Mitochondrion , vol.6 , pp. 136-142
    • Sun, L.1    Luo, C.2    Long, J.3    Wei, D.4    Liu, J.5
  • 25
    • 40949135748 scopus 로고    scopus 로고
    • Lipoamide protects retinal pigment epithelial cells from oxidative stress and mitochondrial dysfunction
    • Li, X., Liu, Z., Luo, C., Jia, H., et al., Lipoamide protects retinal pigment epithelial cells from oxidative stress and mitochondrial dysfunction. Free Radic. Biol. Med. 2008, 44, 1465-1474.
    • (2008) Free Radic. Biol. Med. , vol.44 , pp. 1465-1474
    • Li, X.1    Liu, Z.2    Luo, C.3    Jia, H.4
  • 26
    • 68949173804 scopus 로고    scopus 로고
    • Acrolein induces a cellular stress response and triggers mitochondrial apoptosis in A549 cells
    • Roy, J., Pallepati, P., Bettaieb, A., Tanel, A., Averill-Bates, D. A., Acrolein induces a cellular stress response and triggers mitochondrial apoptosis in A549 cells. Chem. Biol. Interact. 2009, 181, 154-167.
    • (2009) Chem. Biol. Interact. , vol.181 , pp. 154-167
    • Roy, J.1    Pallepati, P.2    Bettaieb, A.3    Tanel, A.4    Averill-Bates, D.A.5
  • 28
    • 0037137190 scopus 로고    scopus 로고
    • Mutagenesis by acrolein-derived propanodeoxyguanosine adducts in human cells
    • Yang, I. Y., Chan, G., Miller, H., Huang, Y., et al., Mutagenesis by acrolein-derived propanodeoxyguanosine adducts in human cells. Biochemistry 2002, 41, 13826-13832.
    • (2002) Biochemistry , vol.41 , pp. 13826-13832
    • Yang, I.Y.1    Chan, G.2    Miller, H.3    Huang, Y.4
  • 29
    • 0035937726 scopus 로고    scopus 로고
    • Evaluation of the mutagenic potential of the principal DNA adduct of acrolein
    • VanderVeen, L. A., Hashim, M. F., Nechev, L. V., Harris, T. M., et al., Evaluation of the mutagenic potential of the principal DNA adduct of acrolein. J. Biol. Chem. 2001, 276, 9066-9070.
    • (2001) J. Biol. Chem. , vol.276 , pp. 9066-9070
    • VanderVeen, L.A.1    Hashim, M.F.2    Nechev, L.V.3    Harris, T.M.4
  • 30
    • 0035937709 scopus 로고    scopus 로고
    • Responses to the major acrolein-derived deoxyguanosine adduct in Escherichia coli
    • Yang, I. Y., Hossain, M., Miller, H., Khullar, S., et al., Responses to the major acrolein-derived deoxyguanosine adduct in Escherichia coli. J. Biol. Chem. 2001, 276, 9071-9076.
    • (2001) J. Biol. Chem. , vol.276 , pp. 9071-9076
    • Yang, I.Y.1    Hossain, M.2    Miller, H.3    Khullar, S.4
  • 31
    • 0031718424 scopus 로고    scopus 로고
    • Molecular analysis of mutations induced by acrolein in human fibroblast cells using supF shuttle vector plasmids
    • Kawanishi, M., Matsuda, T., Nakayama, A., Takebe, H., et al., Molecular analysis of mutations induced by acrolein in human fibroblast cells using supF shuttle vector plasmids. Mutat. Res. 1998, 417, 65-73.
    • (1998) Mutat. Res. , vol.417 , pp. 65-73
    • Kawanishi, M.1    Matsuda, T.2    Nakayama, A.3    Takebe, H.4
  • 32
    • 0037166301 scopus 로고    scopus 로고
    • Error prone translesion synthesis past gamma-hydroxypropano deoxyguanosine, the primary acrolein-derived adduct in mammalian cells
    • Kanuri, M., Minko, I. G., Nechev, L. V., Harris, T. M., et al., Error prone translesion synthesis past gamma-hydroxypropano deoxyguanosine, the primary acrolein-derived adduct in mammalian cells. J. Biol. Chem. 2002, 277, 18257-18265.
    • (2002) J. Biol. Chem. , vol.277 , pp. 18257-18265
    • Kanuri, M.1    Minko, I.G.2    Nechev, L.V.3    Harris, T.M.4
  • 33
    • 0042878463 scopus 로고    scopus 로고
    • Comparative evaluation of the bioreactivity and mutagenic spectra of acrolein-derived alpha-HOPdG and gamma-HOPdG regioisomeric deoxyguanosine adducts
    • Sanchez, A. M., Minko, I. G., Kurtz, A. J., Kanuri, M., et al., Comparative evaluation of the bioreactivity and mutagenic spectra of acrolein-derived alpha-HOPdG and gamma-HOPdG regioisomeric deoxyguanosine adducts. Chem. Res. Toxicol. 2003, 16, 1019-1028.
    • (2003) Chem. Res. Toxicol. , vol.16 , pp. 1019-1028
    • Sanchez, A.M.1    Minko, I.G.2    Kurtz, A.J.3    Kanuri, M.4
  • 34
    • 0037428474 scopus 로고    scopus 로고
    • Translesion synthesis past acrolein-derived DNA adduct, gamma-hydroxypropanodeoxyguanosine, by yeast and human DNA polymerase eta
    • Minko, I. G., Washington, M. T., Kanuri, M., Prakash, L., et al., Translesion synthesis past acrolein-derived DNA adduct, gamma-hydroxypropanodeoxyguanosine, by yeast and human DNA polymerase eta. J. Biol. Chem. 2003, 278, 784-790.
    • (2003) J. Biol. Chem. , vol.278 , pp. 784-790
    • Minko, I.G.1    Washington, M.T.2    Kanuri, M.3    Prakash, L.4
  • 35
    • 49049091162 scopus 로고    scopus 로고
    • Interstrand DNA cross-links induced by alpha, beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources
    • Stone, M. P., Cho, Y. J., Huang, H., Kim, H. Y., et al., Interstrand DNA cross-links induced by alpha, beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources. Acc. Chem. Res. 2008, 41, 793-804.
    • (2008) Acc. Chem. Res. , vol.41 , pp. 793-804
    • Stone, M.P.1    Cho, Y.J.2    Huang, H.3    Kim, H.Y.4
  • 36
    • 37249015575 scopus 로고    scopus 로고
    • Mutagenic potential of DNA-peptide crosslinks mediated by acrolein-derived DNA adducts
    • Minko, I. G., Kozekov, I. D., Kozekova, A., Harris, T. M., et al., Mutagenic potential of DNA-peptide crosslinks mediated by acrolein-derived DNA adducts. Mutat. Res. 2008, 637, 161-172.
    • (2008) Mutat. Res. , vol.637 , pp. 161-172
    • Minko, I.G.1    Kozekov, I.D.2    Kozekova, A.3    Harris, T.M.4
  • 37
    • 77954820678 scopus 로고    scopus 로고
    • Minor groove orientation of the KWKK peptide tethered via the N-terminal amine to the acrolein-derived 1,N2-gamma-hydroxypropanodeoxyguanosine lesion with a trimethylene linkage
    • Huang, H., Kozekov, I. D., Kozekova, A., Rizzo, C. J., et al., Minor groove orientation of the KWKK peptide tethered via the N-terminal amine to the acrolein-derived 1, N2-gamma-hydroxypropanodeoxyguanosine lesion with a trimethylene linkage. Biochemistry 2010, 49, 6155-6164.
    • (2010) Biochemistry , vol.49 , pp. 6155-6164
    • Huang, H.1    Kozekov, I.D.2    Kozekova, A.3    Rizzo, C.J.4
  • 38
    • 0036955117 scopus 로고    scopus 로고
    • CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation
    • Alexandrov, K., Cascorbi, I., Rojas, M., Bouvier, G., et al., CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation. Carcinogenesis 2002, 23, 1969-1977.
    • (2002) Carcinogenesis , vol.23 , pp. 1969-1977
    • Alexandrov, K.1    Cascorbi, I.2    Rojas, M.3    Bouvier, G.4
  • 39
    • 3242794371 scopus 로고    scopus 로고
    • DNA adducts in tumour, normal peripheral lung and bronchus, and peripheral blood lymphocytes from smoking and non-smoking lung cancer patients: correlations between tissues and detection by 32P-postlabelling and immunoassay
    • Gyorffy, E., Anna, L., Gyori, Z., Segesdi, J., et al., DNA adducts in tumour, normal peripheral lung and bronchus, and peripheral blood lymphocytes from smoking and non-smoking lung cancer patients: correlations between tissues and detection by 32P-postlabelling and immunoassay. Carcinogenesis 2004, 25, 1201-1209.
    • (2004) Carcinogenesis , vol.25 , pp. 1201-1209
    • Gyorffy, E.1    Anna, L.2    Gyori, Z.3    Segesdi, J.4
  • 41
    • 0033864802 scopus 로고    scopus 로고
    • The molecular effects of acrolein
    • Kehrer, J. P., Biswal, S. S., The molecular effects of acrolein. Toxicol. Sci. 2000, 57, 6-15.
    • (2000) Toxicol. Sci. , vol.57 , pp. 6-15
    • Kehrer, J.P.1    Biswal, S.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.