-
1
-
-
38949113159
-
Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease
-
Stevens, J. F., Maier, C. S., Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease. Mol. Nutr. Food Res. 2008, 52, 7-25.
-
(2008)
Mol. Nutr. Food Res.
, vol.52
, pp. 7-25
-
-
Stevens, J.F.1
Maier, C.S.2
-
2
-
-
0029824077
-
Lipid peroxidation as a potential endogenous source for the formation of exocyclic DNA adducts
-
Chung, F. L., Chen, H. J., Nath, R. G., Lipid peroxidation as a potential endogenous source for the formation of exocyclic DNA adducts. Carcinogenesis 1996, 17, 2105-2111.
-
(1996)
Carcinogenesis
, vol.17
, pp. 2105-2111
-
-
Chung, F.L.1
Chen, H.J.2
Nath, R.G.3
-
3
-
-
80052602103
-
-
Concise International Chemical Assessment Document, No. 43 (World health Organization)
-
Comes R, M. M., Eggleton M, Concise International Chemical Assessment Document, No. 43 (World health Organization), 2002.
-
(2002)
-
-
Comes, R.M.M.1
Eggleton, M.2
-
4
-
-
0025814980
-
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
-
Esterbauer, H., Schaur, R. J., Zollner, H., Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 1991, 11, 81-128.
-
(1991)
Free Radic. Biol. Med.
, vol.11
, pp. 81-128
-
-
Esterbauer, H.1
Schaur, R.J.2
Zollner, H.3
-
5
-
-
67649933847
-
Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha, beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal
-
Minko, I. G., Kozekov, I. D., Harris, T. M., Rizzo, C. J., et al., Chemistry and biology of DNA containing 1, N(2)-deoxyguanosine adducts of the alpha, beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal. Chem. Res. Toxicol. 2009, 22, 759-778.
-
(2009)
Chem. Res. Toxicol.
, vol.22
, pp. 759-778
-
-
Minko, I.G.1
Kozekov, I.D.2
Harris, T.M.3
Rizzo, C.J.4
-
6
-
-
0021319465
-
Formation of cyclic 1,N2-propanodeoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde
-
Chung, F. L., Young, R., Hecht, S. S., Formation of cyclic 1, N2-propanodeoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde. Cancer Res. 1984, 44, 990-995.
-
(1984)
Cancer Res.
, vol.44
, pp. 990-995
-
-
Chung, F.L.1
Young, R.2
Hecht, S.S.3
-
7
-
-
33244473082
-
Determination of toxic carbonyl compounds in cigarette smoke
-
Fujioka, K., Shibamoto, T., Determination of toxic carbonyl compounds in cigarette smoke. Environ. Toxicol. 2006, 21, 47-54.
-
(2006)
Environ. Toxicol.
, vol.21
, pp. 47-54
-
-
Fujioka, K.1
Shibamoto, T.2
-
8
-
-
36849019121
-
Mechanisms of acrolein-induced myocardial dysfunction: implications for environmental and endogenous aldehyde exposure
-
Luo, J., Hill, B. G., Gu, Y., Cai, J., et al., Mechanisms of acrolein-induced myocardial dysfunction: implications for environmental and endogenous aldehyde exposure. Am. J. Physiol. Heart Circ. Physiol. 2007, 293, H3673-H3684.
-
(2007)
Am. J. Physiol. Heart Circ. Physiol.
, vol.293
-
-
Luo, J.1
Hill, B.G.2
Gu, Y.3
Cai, J.4
-
9
-
-
33750282261
-
Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair
-
Feng, Z., Hu, W., Hu, Y., Tang, M. S., Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair. Proc. Natl. Acad. Sci. USA 2006, 103, 15404-15409.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 15404-15409
-
-
Feng, Z.1
Hu, W.2
Hu, Y.3
Tang, M.S.4
-
10
-
-
34248524522
-
Detection and quantitation of acrolein-derived 1,N2-propanodeoxyguanosine adducts in human lung by liquid chromatography-electrospray ionization-tandem mass spectrometry
-
Zhang, S., Villalta, P. W., Wang, M., Hecht, S. S., Detection and quantitation of acrolein-derived 1, N2-propanodeoxyguanosine adducts in human lung by liquid chromatography-electrospray ionization-tandem mass spectrometry. Chem. Res. Toxicol. 2007, 20, 565-571.
-
(2007)
Chem. Res. Toxicol.
, vol.20
, pp. 565-571
-
-
Zhang, S.1
Villalta, P.W.2
Wang, M.3
Hecht, S.S.4
-
11
-
-
65949095199
-
Mutagenicity and sequence specificity of acrolein-DNA adducts
-
Wang, H. T., Zhang, S., Hu, Y., Tang, M. S., Mutagenicity and sequence specificity of acrolein-DNA adducts. Chem. Res. Toxicol. 2009, 22, 511-517.
-
(2009)
Chem. Res. Toxicol.
, vol.22
, pp. 511-517
-
-
Wang, H.T.1
Zhang, S.2
Hu, Y.3
Tang, M.S.4
-
12
-
-
0033153762
-
Role of O6-alkylguanine-DNA alkyltransferase in protecting against cyclophosphamide-induced toxicity and mutagenicity
-
Cai, Y., Wu, M. H., Ludeman, S. M., Grdina, D. J., Dolan, M. E., Role of O6-alkylguanine-DNA alkyltransferase in protecting against cyclophosphamide-induced toxicity and mutagenicity. Cancer Res. 1999, 59, 3059-3063.
-
(1999)
Cancer Res.
, vol.59
, pp. 3059-3063
-
-
Cai, Y.1
Wu, M.H.2
Ludeman, S.M.3
Grdina, D.J.4
Dolan, M.E.5
-
13
-
-
0034287446
-
Effect of O6-benzylguanine on alkylating agent-induced toxicity and mutagenicity. In Chinese hamster ovary cells expressing wild-type and mutant O6-alkylguanine-DNA alkyltransferases
-
Cai, Y., Wu, M. H., Xu-Welliver, M., Pegg, A. E., Effect of O6-benzylguanine on alkylating agent-induced toxicity and mutagenicity. In Chinese hamster ovary cells expressing wild-type and mutant O6-alkylguanine-DNA alkyltransferases. Cancer Res. 2000, 60, 5464-5469.
-
(2000)
Cancer Res.
, vol.60
, pp. 5464-5469
-
-
Cai, Y.1
Wu, M.H.2
Xu-Welliver, M.3
Pegg, A.E.4
-
14
-
-
34447342240
-
Role of MGMT in protecting against cyclophosphamide-induced toxicity in cells and animals
-
Hansen, R. J., Ludeman, S. M., Paikoff, S. J., Pegg, A. E., Dolan, M. E., Role of MGMT in protecting against cyclophosphamide-induced toxicity in cells and animals. DNA Repair 2007, 6, 1145-1154.
-
(2007)
DNA Repair
, vol.6
, pp. 1145-1154
-
-
Hansen, R.J.1
Ludeman, S.M.2
Paikoff, S.J.3
Pegg, A.E.4
Dolan, M.E.5
-
15
-
-
33947412631
-
Inhibition of acrolein-induced apoptosis by the antioxidant N-acetylcysteine
-
Tanel, A., Averill-Bates, D. A., Inhibition of acrolein-induced apoptosis by the antioxidant N-acetylcysteine. J. Pharmacol. Exp. Ther. 2007, 321, 73-83.
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.321
, pp. 73-83
-
-
Tanel, A.1
Averill-Bates, D.A.2
-
16
-
-
39049192115
-
NTP Technical Report on the comparative toxicity studies of allyl acetate (CAS No. 591-87-7), allyl alcohol (CAS No. 107-18-6) and acrolein (CAS No. 107-02-8) administered by gavage to F344/N rats and B6C3F1 mice
-
Irwin, R. D., NTP Technical Report on the comparative toxicity studies of allyl acetate (CAS No. 591-87-7), allyl alcohol (CAS No. 107-18-6) and acrolein (CAS No. 107-02-8) administered by gavage to F344/N rats and B6C3F1 mice. Toxic Rep. Ser. 2006, 1-73, A71-H10.
-
(2006)
Toxic Rep. Ser.
, vol.1-73
-
-
Irwin, R.D.1
-
17
-
-
67650739174
-
Protective effect of lipoic acid against acrolein-induced cytotoxicity in IMR-90 human fibroblasts
-
Jia, L., Zhang, Z., Zhai, L., Bai, Y., Protective effect of lipoic acid against acrolein-induced cytotoxicity in IMR-90 human fibroblasts. J. Nutr. Sci. Vitaminol. 2009, 55, 126-130.
-
(2009)
J. Nutr. Sci. Vitaminol.
, vol.55
, pp. 126-130
-
-
Jia, L.1
Zhang, Z.2
Zhai, L.3
Bai, Y.4
-
18
-
-
0023749524
-
Mutagenesis of xeroderma pigmentosum fibroblasts by acrolein
-
Curren, R. D., Yang, L. L., Conklin, P. M., Grafstrom, R. C., Harris, C. C., Mutagenesis of xeroderma pigmentosum fibroblasts by acrolein. Mutat. Res. 1988, 209, 17-22.
-
(1988)
Mutat. Res.
, vol.209
, pp. 17-22
-
-
Curren, R.D.1
Yang, L.L.2
Conklin, P.M.3
Grafstrom, R.C.4
Harris, C.C.5
-
19
-
-
37549053570
-
Lack of mutagenicity of acrolein-induced DNA adducts in mouse and human cells
-
Kim, S. I., Pfeifer, G. P., Besaratinia, A., Lack of mutagenicity of acrolein-induced DNA adducts in mouse and human cells. Cancer Res. 2007, 67, 11640-11647.
-
(2007)
Cancer Res.
, vol.67
, pp. 11640-11647
-
-
Kim, S.I.1
Pfeifer, G.P.2
Besaratinia, A.3
-
20
-
-
77950888687
-
Acrolein induces apoptosis through the death receptor pathway in A549 lung cells: role of p53
-
Roy, J., Pallepati, P., Bettaieb, A., Averill-Bates, D. A., Acrolein induces apoptosis through the death receptor pathway in A549 lung cells: role of p53. Can. J. Physiol. Pharmacol. 2010, 88, 353-368.
-
(2010)
Can. J. Physiol. Pharmacol.
, vol.88
, pp. 353-368
-
-
Roy, J.1
Pallepati, P.2
Bettaieb, A.3
Averill-Bates, D.A.4
-
21
-
-
0037154352
-
Acrolein-induced cell death: a caspase-influenced decision between apoptosis and oncosis/necrosis
-
Kern, J. C., Kehrer, J. P., Acrolein-induced cell death: a caspase-influenced decision between apoptosis and oncosis/necrosis. Chem. Biol. Interact. 2002, 139, 79-95.
-
(2002)
Chem. Biol. Interact.
, vol.139
, pp. 79-95
-
-
Kern, J.C.1
Kehrer, J.P.2
-
22
-
-
24644490031
-
Acrolein-induced cell death in PC12 cells: role of mitochondria-mediated oxidative stress
-
Luo, J., Robinson, J. P., Shi, R., Acrolein-induced cell death in PC12 cells: role of mitochondria-mediated oxidative stress. Neurochem. Int. 2005, 47, 449-457.
-
(2005)
Neurochem. Int.
, vol.47
, pp. 449-457
-
-
Luo, J.1
Robinson, J.P.2
Shi, R.3
-
23
-
-
17444421537
-
The aldehyde acrolein induces apoptosis via activation of the mitochondrial pathway
-
Tanel, A., Averill-Bates, D. A., The aldehyde acrolein induces apoptosis via activation of the mitochondrial pathway. Biochim. Biophys. Acta 2005, 1743, 255-267.
-
(2005)
Biochim. Biophys. Acta
, pp. 255-267
-
-
Tanel, A.1
Averill-Bates, D.A.2
-
24
-
-
33745132417
-
Acrolein is a mitochondrial toxin: effects on respiratory function and enzyme activities in isolated rat liver mitochondria
-
Sun, L., Luo, C., Long, J., Wei, D., Liu, J., Acrolein is a mitochondrial toxin: effects on respiratory function and enzyme activities in isolated rat liver mitochondria. Mitochondrion 2006, 6, 136-142.
-
(2006)
Mitochondrion
, vol.6
, pp. 136-142
-
-
Sun, L.1
Luo, C.2
Long, J.3
Wei, D.4
Liu, J.5
-
25
-
-
40949135748
-
Lipoamide protects retinal pigment epithelial cells from oxidative stress and mitochondrial dysfunction
-
Li, X., Liu, Z., Luo, C., Jia, H., et al., Lipoamide protects retinal pigment epithelial cells from oxidative stress and mitochondrial dysfunction. Free Radic. Biol. Med. 2008, 44, 1465-1474.
-
(2008)
Free Radic. Biol. Med.
, vol.44
, pp. 1465-1474
-
-
Li, X.1
Liu, Z.2
Luo, C.3
Jia, H.4
-
26
-
-
68949173804
-
Acrolein induces a cellular stress response and triggers mitochondrial apoptosis in A549 cells
-
Roy, J., Pallepati, P., Bettaieb, A., Tanel, A., Averill-Bates, D. A., Acrolein induces a cellular stress response and triggers mitochondrial apoptosis in A549 cells. Chem. Biol. Interact. 2009, 181, 154-167.
-
(2009)
Chem. Biol. Interact.
, vol.181
, pp. 154-167
-
-
Roy, J.1
Pallepati, P.2
Bettaieb, A.3
Tanel, A.4
Averill-Bates, D.A.5
-
28
-
-
0037137190
-
Mutagenesis by acrolein-derived propanodeoxyguanosine adducts in human cells
-
Yang, I. Y., Chan, G., Miller, H., Huang, Y., et al., Mutagenesis by acrolein-derived propanodeoxyguanosine adducts in human cells. Biochemistry 2002, 41, 13826-13832.
-
(2002)
Biochemistry
, vol.41
, pp. 13826-13832
-
-
Yang, I.Y.1
Chan, G.2
Miller, H.3
Huang, Y.4
-
29
-
-
0035937726
-
Evaluation of the mutagenic potential of the principal DNA adduct of acrolein
-
VanderVeen, L. A., Hashim, M. F., Nechev, L. V., Harris, T. M., et al., Evaluation of the mutagenic potential of the principal DNA adduct of acrolein. J. Biol. Chem. 2001, 276, 9066-9070.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9066-9070
-
-
VanderVeen, L.A.1
Hashim, M.F.2
Nechev, L.V.3
Harris, T.M.4
-
30
-
-
0035937709
-
Responses to the major acrolein-derived deoxyguanosine adduct in Escherichia coli
-
Yang, I. Y., Hossain, M., Miller, H., Khullar, S., et al., Responses to the major acrolein-derived deoxyguanosine adduct in Escherichia coli. J. Biol. Chem. 2001, 276, 9071-9076.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9071-9076
-
-
Yang, I.Y.1
Hossain, M.2
Miller, H.3
Khullar, S.4
-
31
-
-
0031718424
-
Molecular analysis of mutations induced by acrolein in human fibroblast cells using supF shuttle vector plasmids
-
Kawanishi, M., Matsuda, T., Nakayama, A., Takebe, H., et al., Molecular analysis of mutations induced by acrolein in human fibroblast cells using supF shuttle vector plasmids. Mutat. Res. 1998, 417, 65-73.
-
(1998)
Mutat. Res.
, vol.417
, pp. 65-73
-
-
Kawanishi, M.1
Matsuda, T.2
Nakayama, A.3
Takebe, H.4
-
32
-
-
0037166301
-
Error prone translesion synthesis past gamma-hydroxypropano deoxyguanosine, the primary acrolein-derived adduct in mammalian cells
-
Kanuri, M., Minko, I. G., Nechev, L. V., Harris, T. M., et al., Error prone translesion synthesis past gamma-hydroxypropano deoxyguanosine, the primary acrolein-derived adduct in mammalian cells. J. Biol. Chem. 2002, 277, 18257-18265.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18257-18265
-
-
Kanuri, M.1
Minko, I.G.2
Nechev, L.V.3
Harris, T.M.4
-
33
-
-
0042878463
-
Comparative evaluation of the bioreactivity and mutagenic spectra of acrolein-derived alpha-HOPdG and gamma-HOPdG regioisomeric deoxyguanosine adducts
-
Sanchez, A. M., Minko, I. G., Kurtz, A. J., Kanuri, M., et al., Comparative evaluation of the bioreactivity and mutagenic spectra of acrolein-derived alpha-HOPdG and gamma-HOPdG regioisomeric deoxyguanosine adducts. Chem. Res. Toxicol. 2003, 16, 1019-1028.
-
(2003)
Chem. Res. Toxicol.
, vol.16
, pp. 1019-1028
-
-
Sanchez, A.M.1
Minko, I.G.2
Kurtz, A.J.3
Kanuri, M.4
-
34
-
-
0037428474
-
Translesion synthesis past acrolein-derived DNA adduct, gamma-hydroxypropanodeoxyguanosine, by yeast and human DNA polymerase eta
-
Minko, I. G., Washington, M. T., Kanuri, M., Prakash, L., et al., Translesion synthesis past acrolein-derived DNA adduct, gamma-hydroxypropanodeoxyguanosine, by yeast and human DNA polymerase eta. J. Biol. Chem. 2003, 278, 784-790.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 784-790
-
-
Minko, I.G.1
Washington, M.T.2
Kanuri, M.3
Prakash, L.4
-
35
-
-
49049091162
-
Interstrand DNA cross-links induced by alpha, beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources
-
Stone, M. P., Cho, Y. J., Huang, H., Kim, H. Y., et al., Interstrand DNA cross-links induced by alpha, beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources. Acc. Chem. Res. 2008, 41, 793-804.
-
(2008)
Acc. Chem. Res.
, vol.41
, pp. 793-804
-
-
Stone, M.P.1
Cho, Y.J.2
Huang, H.3
Kim, H.Y.4
-
36
-
-
37249015575
-
Mutagenic potential of DNA-peptide crosslinks mediated by acrolein-derived DNA adducts
-
Minko, I. G., Kozekov, I. D., Kozekova, A., Harris, T. M., et al., Mutagenic potential of DNA-peptide crosslinks mediated by acrolein-derived DNA adducts. Mutat. Res. 2008, 637, 161-172.
-
(2008)
Mutat. Res.
, vol.637
, pp. 161-172
-
-
Minko, I.G.1
Kozekov, I.D.2
Kozekova, A.3
Harris, T.M.4
-
37
-
-
77954820678
-
Minor groove orientation of the KWKK peptide tethered via the N-terminal amine to the acrolein-derived 1,N2-gamma-hydroxypropanodeoxyguanosine lesion with a trimethylene linkage
-
Huang, H., Kozekov, I. D., Kozekova, A., Rizzo, C. J., et al., Minor groove orientation of the KWKK peptide tethered via the N-terminal amine to the acrolein-derived 1, N2-gamma-hydroxypropanodeoxyguanosine lesion with a trimethylene linkage. Biochemistry 2010, 49, 6155-6164.
-
(2010)
Biochemistry
, vol.49
, pp. 6155-6164
-
-
Huang, H.1
Kozekov, I.D.2
Kozekova, A.3
Rizzo, C.J.4
-
38
-
-
0036955117
-
CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation
-
Alexandrov, K., Cascorbi, I., Rojas, M., Bouvier, G., et al., CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation. Carcinogenesis 2002, 23, 1969-1977.
-
(2002)
Carcinogenesis
, vol.23
, pp. 1969-1977
-
-
Alexandrov, K.1
Cascorbi, I.2
Rojas, M.3
Bouvier, G.4
-
39
-
-
3242794371
-
DNA adducts in tumour, normal peripheral lung and bronchus, and peripheral blood lymphocytes from smoking and non-smoking lung cancer patients: correlations between tissues and detection by 32P-postlabelling and immunoassay
-
Gyorffy, E., Anna, L., Gyori, Z., Segesdi, J., et al., DNA adducts in tumour, normal peripheral lung and bronchus, and peripheral blood lymphocytes from smoking and non-smoking lung cancer patients: correlations between tissues and detection by 32P-postlabelling and immunoassay. Carcinogenesis 2004, 25, 1201-1209.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1201-1209
-
-
Gyorffy, E.1
Anna, L.2
Gyori, Z.3
Segesdi, J.4
-
40
-
-
0029438708
-
Fate and effects of acrolein
-
Ghilarducci, D. P., Tjeerdema, R. S., Fate and effects of acrolein. Rev. Environ. Contam. Toxicol. 1995, 144, 95-146.
-
(1995)
Rev. Environ. Contam. Toxicol.
, vol.144
, pp. 95-146
-
-
Ghilarducci, D.P.1
Tjeerdema, R.S.2
-
41
-
-
0033864802
-
The molecular effects of acrolein
-
Kehrer, J. P., Biswal, S. S., The molecular effects of acrolein. Toxicol. Sci. 2000, 57, 6-15.
-
(2000)
Toxicol. Sci.
, vol.57
, pp. 6-15
-
-
Kehrer, J.P.1
Biswal, S.S.2
|