TorsinA rescues ER-associated stress and locomotive defects in C. elegans models of ALS

DMM Disease Models and Mechanisms

Volumn 7, Issue 2, 2014, Pages 233-243

  Thompson, Michelle L ^a   Chen, Pan ^a   Yan, Xiaohui ^a   Kim, Hanna ^a   Borom, Akeem R ^a   Roberts, Nathan B ^a   Caldwell, Kim A ^a,b   Caldwell, Guy A ^a,b  

^a UNIVERSITY OF ALABAMA   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

ALS; Chaperone; ER stress; Neurotransmission; TorsinA

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; CHAPERONE; GREEN FLUORESCENT PROTEIN; PROTEASOME; SUPEROXIDE DISMUTASE; TOR1A PROTEIN, HUMAN;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL; CAENORHABDITIS ELEGANS; DISEASE MODEL; ENDOPLASMIC RETICULUM STRESS; GENETICS; HUMAN; METABOLISM; MOTOR ACTIVITY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN DEGRADATION; SYNAPSE; SYNAPTIC TRANSMISSION; TRANSGENIC ANIMAL;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM STRESS; GREEN FLUORESCENT PROTEINS; HUMANS; MOLECULAR CHAPERONES; MOTOR ACTIVITY; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; SUPEROXIDE DISMUTASE; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 84894350876     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.013615     Document Type: Article

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