TDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegans

PLoS Genetics

Volumn 8, Issue 7, 2012, Pages

  Vaccaro, Alexandra ^a,b,c   Tauffenberger, Arnaud ^a,b,c   Ash, Peter E A ^d   Carlomagno, Yari ^d   Petrucelli, Leonard ^d   Parker, J Alex ^a,b,c  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF MONTREAL   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUSED IN SARCOMA PROTEIN; SOMATOMEDIN; TAR DNA BINDING PROTEIN; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR FKHRL1;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CAENORHABDITIS ELEGANS; CELL FUNCTION; CELL SURVIVAL; CELLULAR STRESS SIGNAL; CONTROLLED STUDY; CYTOTOXICITY; GENE; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENETIC ASSOCIATION; LONGEVITY; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; NONHUMAN; OSMOTIC STRESS; OXIDATIVE STRESS; PROTEIN AGGREGATION; PROTEIN FUNCTION; PROTEOTOXICITY; SIGNAL TRANSDUCTION; TAR DNA BINDING PROTEIN 43 GENE; TOXICITY; UPREGULATION; WILD TYPE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DNA-BINDING PROTEINS; FRONTOTEMPORAL DEMENTIA; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HUMANS; INSULIN; LONGEVITY; NEURONS; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; SOMATOMEDINS; TRANSCRIPTION FACTORS;

CAENORHABDITIS ELEGANS;

EID: 84864606276     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002806     Document Type: Article

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