Combination of adenoviral virotherapy and temozolomide chemotherapy eradicates malignant glioma through autophagic and apoptotic cell death in vivo

British Journal of Cancer

Volumn 100, Issue 7, 2009, Pages 1154-1164

  Ulasov, I V ^a   Sonabend, A M ^a   Nandi, S ^a   Khramtsov, A ^a   Han, Y ^a   Lesniak, M S ^a,b  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Apoptosis; Autophagy; Brain tumour; Glioma; Oncolytic adenovirus; Temozolomide

Indexed keywords

CASPASE 3; CONDITIONALLY REPLICATING ADENOVIRUS; GLYCOPROTEIN E1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SURVIVIN; TEMOZOLOMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CANCER SURVIVAL; CELL DEATH; DRUG CYTOTOXICITY; EX VIVO STUDY; FEMALE; GENE OVEREXPRESSION; GLIOBLASTOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; LIGHT CHAIN; MOUSE; NONHUMAN; ONCOLYTIC VIROTHERAPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHUTTLE VECTOR; SURVIVAL TIME; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; WESTERN BLOTTING;

ADENOVIRIDAE; ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; APOPTOSIS; AUTOPHAGY; BRAIN NEOPLASMS; CASPASE 3; CELL LINE, TUMOR; COMBINED MODALITY THERAPY; DACARBAZINE; FEMALE; GLIOMA; HUMANS; MICE; MICE, INBRED BALB C; MICROTUBULE-ASSOCIATED PROTEINS; MITOSIS; ONCOLYTIC VIROTHERAPY; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 63949085760     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6604969     Document Type: Article

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