Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 34, 2006, Pages 12873-12878

  Fulci, Giulia ^a,b   Breymann, Laura ^b   Gianni, Davide ^b   Kurozomi, Kazuhiko ^a   Rhee, Sarah S ^b   Yu, Jianhua ^a   Kaur, Balveen ^a   Louis, David N ^b   Weissleder, Ralph ^b   Caligiuri, Michael A ^a   Chiocca, E Antonio ^a,b,c  

^a OHIO STATE UNIVERSITY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

Author keywords

Brain tumor; Gene therapy; Herpes simplex virus; Innate immunity; Oncolytic virus

Indexed keywords

CD163 ANTIGEN; CD68 ANTIGEN; CYCLOPHOSPHAMIDE; GAMMA INTERFERON; ONCOLYTIC VIRUS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TUMOR; CANCER THERAPY; CONTROLLED STUDY; GLIOMA; HERPES SIMPLEX VIRUS; IMMUNOREGULATION; INNATE IMMUNITY; MACROPHAGE; MALE; MICROGLIA; NATURAL KILLER T CELL; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; RAT; VIROTHERAPY; VIRUS REPLICATION;

ANIMALIA; SIMPLEXVIRUS;

EID: 33748088164     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0605496103     Document Type: Article

References (39)

1. Bischoff, J. R., Kirn, D. H., Williams, A., Heise, C., Horn, S., Muna, M., Ng, L., Nye, J. A., Sampson-Johannes, A., Fattaey, A., et al. (1996) Science 274, 373-376.
2. Chiocca, E. A. (2002) Nat. Rev. Cancer 2, 938-950.
3. Fulci, G. & Chiocca, E. A. (2003) Front. Biosci. 8, e346-e360.
4. Gomez-Manzano, C., Balague, C., Alemany, R., Lemoine, M. G., Mitlianga, P., Jiang, H., Khan, A., Alonso, M., Lang, F. F., Conrad, C. A., et al. (2004) Oncogene 23, 1821-1828.
5. Jiang, H., Gomez-Manzano, C., Alemany, R., Medrano, D., Alonso, M., Bekele, B. N., Lin, E., Conrad, C. C., Yung, W. K. & Fueyo J. (2005) Neoplasia 7, 48-56.
6. Martuza, R. L., Malick, A., Markert, J. M., Ruffner, K. L. & Coen, D. M. (1991) Science 252, 854-856.
7. Chiocca, E. A., Abbed, K. M., Tatter, S., Louis, D. N., Hochberg, F. H., Barker, F., Kracher, J., Grossman, S. A., Fisher, J. D., Carson, K., et al. (2004) Mol. Ther. 10, 958-966.
8. Csatary, L. K., Gosztonyi, G., Szeberenyi, J., Fabian, Z., Liszka, V., Bodey, B. & Csatary, C. M. (2004) J. Neurooncol. 67, 83-93.
9. Khuri, F. R., Nemunaitis, J., Ganly, I., Arseneau, J., Tannock, I. F., Romel, L., Gore, M., Ironside, J., MacDougall, R. H., Heise, C., et al. (2000) Nat. Med. 6, 879-885.
10. Lorence, R. M., Pecora, A. L., Major, P. P., Hotte, S. J., Laurie, S. A., Roberts, M. S., Groene, W. S. & Bamat, M. K. (2003) Curr. Opin. Mol. Ther. 5, 618-624.
11. Markert, J. M., Medlock, M. D., Rabkin, S. D., Gillespie, G. Y., Todo, T., Hunter, W. D., Palmer, C. A., Feigenbaum, F., Tornatore, C., Tufaro, F., et al. (2000) Gene Ther. 7, 867-874.
12. Papanastassiou, V., Rampling, R., Fraser, M., Petty, R., Hadley, D., Nicoll, J., Harland, J., Mabbs, R. & Brown, M. (2002) Gene Ther. 9, 398-406.
13. Pecora, A. L., Rizvi, N., Cohen, G. I., Meropol, N. J., Sterman, D., Marshall, J. L., Goldberg, S., Gross, P., O'Neil, J. D., Groene, W. S., et al. (2002) J. Clin. Oncol. 20, 2251-2266.
14. Andreansky, S., He, B., van Cott, J., McGhee, J., Markert, J. M., Gillespie, G. Y., Roizman, B. & Whitley, R. J. (1998) Gene Ther. 5, 121-130.
15. Bennett, J. J., Malhotra, S., Wong, R. J., Delman, K., Zager, J., St. Louis, M., Johnson, P. & Fong, Y. (2001) Ann. Surg. 233, 819-826.
16. Todo, T., Martuza, R. L., Rabkin, S. D. & Johnson, P. A. (2001) Proc. Natl. Acad. Sci. USA 98, 6396-6401.
17. Abordo-Adesida, E., Follenzi, A., Barcia, C., Sciascia, S., Castro, M. G., Naldini, L. & Lowenstein, P. R. (2005) Hum. Gene Ther. 16, 741-751.
18. Balachandran, S., Thomas, E. & Barber, G. N. (2004) Nature 432, 401-405.
19. Balachandran, S. & Barber, G. N. (2004) Cancer Cell 5, 51-65.
20. Friedman, A., Tian, J. P., Fulci, G., Chiocca, E. A. & Wang, J. (2006) Cancer Res. 66, 2314-2319.
21. Lowenstein, P. R. (2005) Mol. Ther. 12, 185-186.
22. Ikeda, K., Ichikawa, T., Wakimoto, H., Silver, J. S., Deisboeck, T. S., Finkelstein, D., Harsh, G. R., Louis, D. N., Bartus, R. T., Hochberg, F. H., et al. (1999) Nat. Med. 5, 881-887.
23. Ikeda, K., Wakimoto, H., Ichikawa, T., Jhung, S., Hochberg, F. H., Louis, D. N. & Chiocca, E. A. (2000) J. Virol. 74, 4765-4775.
24. Wakimoto, H., Johnson, P. R., Knipe, D. M. & Chiocca, E. A. (2003) Gene Ther. 10, 983-990.
25. Wakimoto, H., Fulci, G., Tyminski, E. & Chiocca, E. A. (2004) Gene Ther. 11, 214-223.
26. Moore, A., Weissleder, R. & Bogdanov, A., Jr. (1997) J. Magn. Reson. Imaging 7, 1140-1145.
27. Trotta, R., Parihar, R., Yu, J., Becknell, B., Allard, J., II, Wen, J., Ding, W., Mao, H., Tridandapani, S., Carson, W. E., et al. (2005) Blood 105, 3011-3018.
28. Kirn, D., Martuza, R. L. & Zwiebel, J. (2001) Nat. Med. 7, 781-787.
29. Cooper, M. A., Fehniger, T. A., Turner, S. C., Chen, K. S., Ghaheri, B. A., Ghayur, T., Carson, W. E. & Caligiuri, M. A. (2001) Blood 97, 3146-3151.
30. Hickey, W. F. (1999) Semin. Immunol. 11, 125-137.
31. Bishop, G. A., Marlin, S. D., Schwartz, S. A. & Glorioso, J. C. (1984) J. Immunol. 133, 2207-2214.
32. Bishop, G. A., Kumel, G., Schwartz, S. A. & Glorioso, J. C. (1986) J. Virol. 57, 294-300.
33. Cooper, A. M., Fehniger, A. T. & Caligiuri, A. M. (2001) Trends Immunol. 22, 633-640.
34. Bluman, M. E., Bartynski, J. K., Avalos, R. B. & Caligiuri A. M. (1996) J. Clin. Invest. 97, 2722-2727.
35. Fehniger, A. T., Herbein, G., Yu, H., Para, I. M., Bernstein, P. Z., O'Brien, A. W. & Caligiuri, A. M. (1998) J. Immunol. 161, 6433-6438.
36. Guillemin, G. J. & Brew, B. J. (2004) J. Leukoc. Biol. 75, 388-397.
37. Strik, H. M., Stoll, M. & Meyermann, R. (2004) Anticancer Res. 24, 37-42.
38. Kambara, H., Saeki, Y. & Chiocca, E. A. (2005) Cancer Res. 65, 11255-11258.
39. Goldstein, D. J. & Weller, S. K. (1988) J. Virol. 62, 2970-2977.