Hypoxia enhances the replication of oncolytic herpes simplex virus

Molecular Therapy

Volumn 17, Issue 1, 2009, Pages 51-56

  Aghi, Manish K ^a   Liu, Ta Chiang ^b   Rabkin, Samuel ^c   Martuza, Robert L ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b WASHINGTON UNIVERSITY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; G 207; GENE PRODUCT; MESSENGER RNA; PROTEIN GADD34; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER RESISTANCE; CELL HYPOXIA; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; GENE DELETION; GLIOBLASTOMA; GLIOMA CELL; HERPES; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; HYPERBARIC OXYGEN; HYPOXIA; MOUSE; NONHUMAN; ONCOLYTIC VIROTHERAPY; PROTEIN DETERMINATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE OXYGENATION; UPREGULATION; VIRUS REPLICATION; VIRUS STRAIN; WILD TYPE;

ANIMALS; ANOXIA; BLOTTING, WESTERN; CELL LINE, TUMOR; GLIOBLASTOMA; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, NUDE; ONCOLYTIC VIROTHERAPY; ONCOLYTIC VIRUSES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIMPLEXVIRUS; VIRUS REPLICATION;

MUS; SIMPLEXVIRUS;

EID: 58149214278     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2008.232     Document Type: Article

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