메뉴 건너뛰기




Volumn 69, Issue , 2014, Pages 219-228

Salvianolic acid A protects RPE cells against oxidative stress through activation of Nrf2/HO-1 signaling

Author keywords

Age related macular degeneration; Akt mTOR; Free radicals; HO 1; Nrf2; Oxidative stress; Salvianolic acid A

Indexed keywords

AGE-RELATED MACULAR DEGENERATION; AKT/MTOR; FREE RADICALS; HO-1; NRF2; OXIDATIVE STRESS; SALVIANOLIC ACID A;

EID: 84894233729     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.01.025     Document Type: Article
Times cited : (231)

References (57)
  • 1
    • 1842530296 scopus 로고    scopus 로고
    • Causes and prevalence of visual impairment among adults in the united states
    • DOI 10.1001/archopht.122.4.477
    • N. Congdon, B. OColmain, C.C. Klaver, R. Klein, B. Munoz, D.S. Friedman, J. Kempen, H.R. Taylor, P. Mitchell Eye Diseases Prevalence Research Group Causes and prevalence of visual impairment among adults in the United States Arch. Ophthalmol. 122 2004 477 485 (Pubitemid 38456282)
    • (2004) Archives of Ophthalmology , vol.122 , Issue.4 , pp. 477-485
    • Congdon, N.1
  • 4
    • 0023863371 scopus 로고
    • Solar radiation and age-related macular degeneration
    • DOI 10.1016/0039-6257(88)90174-9
    • R.W. Young Solar radiation and age-related macular degeneration Surv. Ophthalmol. 32 1988 252 269 (Pubitemid 18066235)
    • (1988) Survey of Ophthalmology , vol.32 , Issue.4 , pp. 252-269
    • Young, R.W.1
  • 6
    • 0033040503 scopus 로고    scopus 로고
    • Hydrogen peroxide causes significant mitochondrial DNA damage in human RPE cells
    • DOI 10.1006/exer.1998.0661
    • S.W. Ballinger, B. Van Houten, G.F. Jin, C.A. Conklin, and B.F. Godley Hydrogen peroxide causes significant mitochondrial DNA damage in human RPE cells Exp. Eye Res. 68 1999 765 772 (Pubitemid 29290796)
    • (1999) Experimental Eye Research , vol.68 , Issue.6 , pp. 765-772
    • Ballinger, S.W.1    Van Houten, B.2    Conklin, C.A.3    Jin, G.-F.4    Godley, B.F.5
  • 7
    • 79960748368 scopus 로고    scopus 로고
    • The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration
    • Z. Yildirim, N.I. Ucgun, and F. Yildirim The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration Clinics (Sao Paulo) 66 2011 743 746
    • (2011) Clinics (Sao Paulo) , vol.66 , pp. 743-746
    • Yildirim, Z.1    Ucgun, N.I.2    Yildirim, F.3
  • 8
    • 0033795036 scopus 로고    scopus 로고
    • The role of oxidative stress in the pathogenesis of age-related macular degeneration
    • S. Beatty, H. Koh, M. Phil, D. Henson, and M. Boulton The role of oxidative stress in the pathogenesis of age-related macular degeneration Surv. Ophthalmol. 45 2000 115 134
    • (2000) Surv. Ophthalmol. , vol.45 , pp. 115-134
    • Beatty, S.1    Koh, H.2    Phil, M.3    Henson, D.4    Boulton, M.5
  • 10
    • 33847657902 scopus 로고    scopus 로고
    • Long-term exposure to solar ultraviolet radiation as a risk factor for age-related macular degeneration
    • I. Plestina-Borjan, and M. Klinger-Lasic Long-term exposure to solar ultraviolet radiation as a risk factor for age-related macular degeneration Coll. Antropol. 31 Suppl. 1 2007 33 38
    • (2007) Coll. Antropol. , vol.31 , Issue.SUPPL. 1 , pp. 33-38
    • Plestina-Borjan, I.1    Klinger-Lasic, M.2
  • 11
    • 55649114157 scopus 로고    scopus 로고
    • Mitochondrial DNA damage and its potential role in retinal degeneration
    • S.G. Jarrett, H. Lin, B.F. Godley, and M.E. Boulton Mitochondrial DNA damage and its potential role in retinal degeneration Prog. Retinal Eye Res. 27 2008 596 607
    • (2008) Prog. Retinal Eye Res. , vol.27 , pp. 596-607
    • Jarrett, S.G.1    Lin, H.2    Godley, B.F.3    Boulton, M.E.4
  • 12
    • 3042644268 scopus 로고    scopus 로고
    • A randomised controlled trial investigating the effect of nutritional supplementation on visual function in normal, and age-related macular disease affected eyes: Design and methodology
    • H. Bartlett, and F. Eperjesi A randomised controlled trial investigating the effect of nutritional supplementation on visual function in normal, and age-related macular disease affected eyes: design and methodology Nutr. J. 2 2003 12
    • (2003) Nutr. J. , vol.2 , pp. 12
    • Bartlett, H.1    Eperjesi, F.2
  • 13
    • 2542432254 scopus 로고    scopus 로고
    • Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: The Veterans LAST study (Lutein Antioxidant Supplementation Trial)
    • S. Richer, W. Stiles, L. Statkute, J. Pulido, J. Frankowski, D. Rudy, K. Pei, M. Tsipursky, and J. Nyland Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study Optometry 75 2004 216 230 (Pubitemid 39208022)
    • (2004) Optometry , vol.75 , Issue.4 , pp. 216-230
    • Richer, S.1    Stiles, W.2    Statkute, L.3    Pulido, J.4    Frankowski, J.5    Rudy, D.6    Pei, K.7    Tsipursky, M.8    Nyland, J.9
  • 14
    • 0037375044 scopus 로고    scopus 로고
    • Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: A possible mechanism for RPE aging and age-related macular degeneration
    • DOI 10.1016/S0014-4835(03)00023-X
    • F.Q. Liang, and B.F. Godley Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration Exp. Eye Res. 76 2003 397 403 (Pubitemid 36299052)
    • (2003) Experimental Eye Research , vol.76 , Issue.4 , pp. 397-403
    • Liang, F.-Q.1    Godley, B.F.2
  • 15
    • 84862922033 scopus 로고    scopus 로고
    • Protective effect of paeoniflorin against oxidative stress in human retinal pigment epithelium in vitro
    • X. Wankun, Y. Wenzhen, Z. Min, Z. Weiyan, C. Huan, D. Wei, H. Lvzhen, Y. Xu, and L. Xiaoxin Protective effect of paeoniflorin against oxidative stress in human retinal pigment epithelium in vitro Mol. Vision 17 2011 3512 3522
    • (2011) Mol. Vision , vol.17 , pp. 3512-3522
    • Wankun, X.1    Wenzhen, Y.2    Min, Z.3    Weiyan, Z.4    Huan, C.5    Wei, D.6    Lvzhen, H.7    Xu, Y.8    Xiaoxin, L.9
  • 16
    • 75749157843 scopus 로고    scopus 로고
    • Protective effect of clusterin from oxidative stress-induced apoptosis in human retinal pigment epithelial cells
    • J.H. Kim, J.H. Kim, H.O. Jun, Y.S. Yu, B.H. Min, K.H. Park, and K.W. Kim Protective effect of clusterin from oxidative stress-induced apoptosis in human retinal pigment epithelial cells Invest. Ophthalmol. Visual Sci. 51 2010 561 566
    • (2010) Invest. Ophthalmol. Visual Sci. , vol.51 , pp. 561-566
    • Kim, J.H.1    Kim, J.H.2    Jun, H.O.3    Yu, Y.S.4    Min, B.H.5    Park, K.H.6    Kim, K.W.7
  • 17
    • 80054956582 scopus 로고    scopus 로고
    • Rapamycin sensitive mTOR activation mediates nerve growth factor (NGF) induced cell migration and pro-survival effects against hydrogen peroxide in retinal pigment epithelial cells
    • G.F. Cao, Y. Liu, W. Yang, J. Wan, J. Yao, Y. Wan, and Q. Jiang Rapamycin sensitive mTOR activation mediates nerve growth factor (NGF) induced cell migration and pro-survival effects against hydrogen peroxide in retinal pigment epithelial cells Biochem. Biophys. Res. Commun. 414 2011 499 505
    • (2011) Biochem. Biophys. Res. Commun. , vol.414 , pp. 499-505
    • Cao, G.F.1    Liu, Y.2    Yang, W.3    Wan, J.4    Yao, J.5    Wan, Y.6    Jiang, Q.7
  • 18
    • 84878231533 scopus 로고    scopus 로고
    • Ultraviolet (UV) and hydrogen peroxide activate ceramide-ER stress-AMPK signaling axis to promote retinal pigment epithelium (RPE) cell apoptosis
    • J. Yao, H.E. Bi, Y. Sheng, L.B. Cheng, R.L. Wendu, C.H. Wang, G.F. Cao, and Q. Jiang Ultraviolet (UV) and hydrogen peroxide activate ceramide-ER stress-AMPK signaling axis to promote retinal pigment epithelium (RPE) cell apoptosis Int. J. Mol. Sci. 14 2013 10355 10368
    • (2013) Int. J. Mol. Sci. , vol.14 , pp. 10355-10368
    • Yao, J.1    Bi, H.E.2    Sheng, Y.3    Cheng, L.B.4    Wendu, R.L.5    Wang, C.H.6    Cao, G.F.7    Jiang, Q.8
  • 19
    • 84891489863 scopus 로고    scopus 로고
    • Salvianolic acid A promotes the acceleration of neovascularization in the ischemic rat myocardium and the functions of endothelial progenitor cells
    • Y.J. Li, C.L. Duan, and J.X. Liu Salvianolic acid A promotes the acceleration of neovascularization in the ischemic rat myocardium and the functions of endothelial progenitor cells J. Ethnopharmacol. 151 2013 218 227
    • (2013) J. Ethnopharmacol. , vol.151 , pp. 218-227
    • Li, Y.J.1    Duan, C.L.2    Liu, J.X.3
  • 20
    • 0021210939 scopus 로고
    • Salvianolic acid A, a new depside from roots of Salvia miltiorrhiza
    • L. Lian-Niang, T. Rui, and C. Wei-Ming Salvianolic acid A, a new depside from roots of Salvia miltiorrhiza Planta Med. 50 1984 227 228 (Pubitemid 14025689)
    • (1984) Planta Medica , vol.50 , Issue.3 , pp. 227-228
    • Li, L.N.1    Rui, T.2    Chen, W.3
  • 21
    • 0029920512 scopus 로고    scopus 로고
    • Effects of salvianolic acid A on oxygen radicals released by rat neutrophils and on neutrophil function
    • T.J. Lin, K.J. Zhang, and G.T. Liu Effects of salvianolic acid A on oxygen radicals released by rat neutrophils and on neutrophil function Biochem. Pharmacol. 51 1996 1237 1241
    • (1996) Biochem. Pharmacol. , vol.51 , pp. 1237-1241
    • Lin, T.J.1    Zhang, K.J.2    Liu, G.T.3
  • 22
    • 0001705084 scopus 로고
    • Protective effects of salvianolic acid A against impairment of memory induced by cerebral ischemia-reperfusion in mice
    • G. Du, and J. Zhang [Protective effects of salvianolic acid A against impairment of memory induced by cerebral ischemia-reperfusion in mice] Yao xue xue bao (Acta Pharm. Sin.) 30 1995 184
    • (1995) Yao Xue Xue Bao (Acta Pharm. Sin.) , vol.30 , pp. 184
    • Du, G.1    Zhang, J.2
  • 23
    • 80054986462 scopus 로고    scopus 로고
    • Salvianolic acid A suppress lipopolysaccharide-induced NF-kappaB signaling pathway by targeting IKKbeta
    • K.S. Oh, B.K. Oh, J. Mun, H.W. Seo, and B.H. Lee Salvianolic acid A suppress lipopolysaccharide-induced NF-kappaB signaling pathway by targeting IKKbeta Int. Immunopharmacol. 11 2011 1901 1906
    • (2011) Int. Immunopharmacol. , vol.11 , pp. 1901-1906
    • Oh, K.S.1    Oh, B.K.2    Mun, J.3    Seo, H.W.4    Lee, B.H.5
  • 24
    • 77953120701 scopus 로고    scopus 로고
    • Antiplatelet and antithrombotic activities of salvianolic acid A
    • H.Y. Fan, F.H. Fu, M.Y. Yang, H. Xu, A.H. Zhang, and K. Liu Antiplatelet and antithrombotic activities of salvianolic acid A Thromb. Res. 126 2010 e17 e22
    • (2010) Thromb. Res. , vol.126
    • Fan, H.Y.1    Fu, F.H.2    Yang, M.Y.3    Xu, H.4    Zhang, A.H.5    Liu, K.6
  • 25
    • 0034091488 scopus 로고    scopus 로고
    • Effects of salvianolic acid-A on NIH/3T3 fibroblast proliferation, collagen synthesis and gene expression
    • O. Liu, Y.Y. Hu, X.L. Wang, P. Liu, and L.M. Xu Effects of salvianolic acid-A on NIH/3T3 fibroblast proliferation, collagen synthesis and gene expression World J. Gastroenterol. 6 2000 361 364 (Pubitemid 30392130)
    • (2000) World Journal of Gastroenterology , vol.6 , Issue.3 , pp. 361-364
    • Liu, C.H.1    Hu, Y.Y.2    Wang, X.L.3    Liu, P.4    Xu, L.M.5
  • 26
    • 84873703254 scopus 로고    scopus 로고
    • Nrf2-mediated redox signaling in arsenic carcinogenesis: A review
    • D. Sinha, J. Biswas, and A. Bishayee Nrf2-mediated redox signaling in arsenic carcinogenesis: a review Arch. Toxicol. 87 2013 383 396
    • (2013) Arch. Toxicol. , vol.87 , pp. 383-396
    • Sinha, D.1    Biswas, J.2    Bishayee, A.3
  • 27
    • 0024394697 scopus 로고
    • The antioxidant action of N-acetylcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid
    • DOI 10.1016/0891-5849(89)90066-X
    • O.I. Aruoma, B. Halliwell, B.M. Hoey, and J. Butler The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid Free Radic. Biol. Med. 6 1989 593 597 (Pubitemid 19147809)
    • (1989) Free Radical Biology and Medicine , vol.6 , Issue.6 , pp. 593-597
    • Aruoma, O.I.1    Halliwell, B.2    Hoey, B.M.3    Butler, J.4
  • 29
    • 0029831167 scopus 로고    scopus 로고
    • Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002
    • G.J. Brunn, J. Williams, C. Sabers, G. Wiederrecht, J.C. Lawrence Jr, and R.T. Abraham Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002 EMBO J. 15 1996 5256 5267 (Pubitemid 26336209)
    • (1996) EMBO Journal , vol.15 , Issue.19 , pp. 5256-5267
    • Brunn, G.J.1    Williams, J.2    Sabers, C.3    Wiederrecht, G.4    Lawrence Jr., J.C.5    Abraham, R.T.6
  • 30
    • 34249882802 scopus 로고    scopus 로고
    • ATP-sensitive potassium channel: A novel target for protection against UV-induced human skin cell damage
    • DOI 10.1002/jcp.21026
    • C. Cao, S. Healey, A. Amaral, A. Lee-Couture, S. Wan, N. Kouttab, W. Chu, and Y. Wan ATP-sensitive potassium channel: a novel target for protection against UV-induced human skin cell damage J. Cell. Physiol. 212 2007 252 263 (Pubitemid 46867608)
    • (2007) Journal of Cellular Physiology , vol.212 , Issue.1 , pp. 252-263
    • Cao, C.1    Healey, S.2    Amaral, A.3    Lee-Couture, A.4    Wan, S.5    Kouttab, N.6    Chu, W.7    Wan, Y.8
  • 31
    • 84861952859 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha (TNF-alpha)-mediated in vitro human retinal pigment epithelial (RPE) cell migration mainly requires Akt/mTOR complex 1 (mTORC1), but not mTOR complex 2 (mTORC2) signaling
    • Y. Liu, G.F. Cao, J. Xue, J. Wan, Y. Wan, Q. Jiang, and J. Yao Tumor necrosis factor-alpha (TNF-alpha)-mediated in vitro human retinal pigment epithelial (RPE) cell migration mainly requires Akt/mTOR complex 1 (mTORC1), but not mTOR complex 2 (mTORC2) signaling Eur. J. Cell Biol. 91 2012 728 737
    • (2012) Eur. J. Cell Biol. , vol.91 , pp. 728-737
    • Liu, Y.1    Cao, G.F.2    Xue, J.3    Wan, J.4    Wan, Y.5    Jiang, Q.6    Yao, J.7
  • 32
    • 70349325677 scopus 로고    scopus 로고
    • Galpha(i1) and Galpha(i3) are required for epidermal growth factor-mediated activation of the Akt-mTORC1 pathway
    • C. Cao, X. Huang, Y. Han, Y. Wan, L. Birnbaumer, G.S. Feng, J. Marshall, M. Jiang, and W.M. Chu Galpha(i1) and Galpha(i3) are required for epidermal growth factor-mediated activation of the Akt-mTORC1 pathway Sci. Signaling 2 2009 ra17
    • (2009) Sci. Signaling , vol.2 , pp. 17
    • Cao, C.1    Huang, X.2    Han, Y.3    Wan, Y.4    Birnbaumer, L.5    Feng, G.S.6    Marshall, J.7    Jiang, M.8    Chu, W.M.9
  • 33
    • 84868005485 scopus 로고    scopus 로고
    • AMP-activated protein kinase: A target for drugs both ancient and modern
    • D.G. Hardie, F.A. Ross, and S.A. Hawley AMP-activated protein kinase: a target for drugs both ancient and modern Chem. Biol. 19 2012 1222 1236
    • (2012) Chem. Biol. , vol.19 , pp. 1222-1236
    • Hardie, D.G.1    Ross, F.A.2    Hawley, S.A.3
  • 34
    • 84860296724 scopus 로고    scopus 로고
    • AMP-activated protein kinase, stress responses and cardiovascular diseases
    • S. Wang, P. Song, and M.H. Zou AMP-activated protein kinase, stress responses and cardiovascular diseases Clin. Sci. (London) 122 2012 555 573
    • (2012) Clin. Sci. (London) , vol.122 , pp. 555-573
    • Wang, S.1    Song, P.2    Zou, M.H.3
  • 35
    • 84855519804 scopus 로고    scopus 로고
    • Targeting AMPK in the treatment of malignancies
    • E. Vakana, J.K. Altman, and L.C. Platanias Targeting AMPK in the treatment of malignancies J. Cell. Biochem. 113 2012 404 409
    • (2012) J. Cell. Biochem. , vol.113 , pp. 404-409
    • Vakana, E.1    Altman, J.K.2    Platanias, L.C.3
  • 37
    • 77951834544 scopus 로고    scopus 로고
    • Hydrogen peroxide inhibits mTOR signaling by activation of AMPKalpha leading to apoptosis of neuronal cells
    • L. Chen, B. Xu, L. Liu, Y. Luo, J. Yin, H. Zhou, W. Chen, T. Shen, X. Han, and S. Huang Hydrogen peroxide inhibits mTOR signaling by activation of AMPKalpha leading to apoptosis of neuronal cells Lab. Invest. 90 2010 762 773
    • (2010) Lab. Invest. , vol.90 , pp. 762-773
    • Chen, L.1    Xu, B.2    Liu, L.3    Luo, Y.4    Yin, J.5    Zhou, H.6    Chen, W.7    Shen, T.8    Han, X.9    Huang, S.10
  • 39
    • 3142570440 scopus 로고    scopus 로고
    • The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress
    • DOI 10.1016/j.freeradbiomed.2004.04.033, PII S089158490400379X
    • T. Nguyen, C.S. Yang, and C.B. Pickett The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress Free Radic. Biol. Med. 37 2004 433 441 (Pubitemid 38901076)
    • (2004) Free Radical Biology and Medicine , vol.37 , Issue.4 , pp. 433-441
    • Nguyen, T.1    Yang, C.S.2    Pickett, C.B.3
  • 40
    • 1942455887 scopus 로고    scopus 로고
    • Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles
    • DOI 10.1016/j.freeradbiomed.2004.02.075, PII S0891584904001935
    • K. Itoh, K.I. Tong, and M. Yamamoto Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles Free Radic. Biol. Med. 36 2004 1208 1213 (Pubitemid 38526314)
    • (2004) Free Radical Biology and Medicine , vol.36 , Issue.10 , pp. 1208-1213
    • Itoh, K.1    Tong, K.I.2    Yamamoto, M.3
  • 41
    • 71449099635 scopus 로고    scopus 로고
    • Antioxidant-induced modification of INrf2 cysteine 151 and PKC-delta-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance
    • S.K. Niture, A.K. Jain, and A.K. Jaiswal Antioxidant-induced modification of INrf2 cysteine 151 and PKC-delta-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance J. Cell Sci. 122 2009 4452 4464
    • (2009) J. Cell Sci. , vol.122 , pp. 4452-4464
    • Niture, S.K.1    Jain, A.K.2    Jaiswal, A.K.3
  • 42
    • 59849113546 scopus 로고    scopus 로고
    • Molecular mechanisms of Nrf2-mediated antioxidant response
    • W. Li, and A.N. Kong Molecular mechanisms of Nrf2-mediated antioxidant response Mol. Carcinog. 48 2009 91 104
    • (2009) Mol. Carcinog. , vol.48 , pp. 91-104
    • Li, W.1    Kong, A.N.2
  • 44
    • 79151485932 scopus 로고    scopus 로고
    • Nrf-2 mediated heme oxygenase-1 expression, an antioxidant-independent mechanism, contributes to anti-atherogenesis and vascular protective effects of Ginkgo biloba extract
    • J.S. Chen, P.H. Huang, C.H. Wang, F.Y. Lin, H.Y. Tsai, T.C. Wu, S.J. Lin, and J.W. Chen Nrf-2 mediated heme oxygenase-1 expression, an antioxidant-independent mechanism, contributes to anti-atherogenesis and vascular protective effects of Ginkgo biloba extract Atherosclerosis 214 2011 301 309
    • (2011) Atherosclerosis , vol.214 , pp. 301-309
    • Chen, J.S.1    Huang, P.H.2    Wang, C.H.3    Lin, F.Y.4    Tsai, H.Y.5    Wu, T.C.6    Lin, S.J.7    Chen, J.W.8
  • 46
    • 33846449473 scopus 로고    scopus 로고
    • Effects of salvianolic acid A on oxidative stress and liver injury induced by carbon tetrachloride in rats
    • DOI 10.1111/j.1742-7835.2007.00020.x
    • Z.m. Wu, T. Wen, Y.f. Tan, Y. Liu, F. Ren, and H. Wu Effects of salvianolic acid A on oxidative stress and liver injury induced by carbon tetrachloride in rats Basic Clin. Pharmacol. Toxicol. 100 2007 115 120 (Pubitemid 46146715)
    • (2007) Basic and Clinical Pharmacology and Toxicology , vol.100 , Issue.2 , pp. 115-120
    • Wu, Z.-M.1    Wen, T.2    Tan, Y.-F.3    Liu, Y.4    Ren, F.5    Wu, H.6
  • 47
    • 67449141650 scopus 로고    scopus 로고
    • Cardioprotective effect of salvianolic acid A on isoproterenol-induced myocardial infarction in rats
    • S.-b. Wang, S. Tian, F. Yang, H.-g. Yang, X.-y. Yang, and G.-h. Du Cardioprotective effect of salvianolic acid A on isoproterenol-induced myocardial infarction in rats Eur. J. Pharmacol. 615 2009 125 132
    • (2009) Eur. J. Pharmacol. , vol.615 , pp. 125-132
    • Wang, S.-B.1    Tian, S.2    Yang, F.3
  • 49
    • 0030045835 scopus 로고    scopus 로고
    • Heme oxygenase: A novel target for the modulation of the inflammatory response
    • DOI 10.1038/nm0196-87
    • D. Willis, A.R. Moore, R. Frederick, and D.A. Willoughby Heme oxygenase: a novel target for the modulation of the inflammatory response Nat. Med. 2 1996 87 90 (Pubitemid 26029572)
    • (1996) Nature Medicine , vol.2 , Issue.1 , pp. 87-90
    • Willis, D.1    Moore, A.R.2    Frederick, R.3    Willoughby, D.A.4
  • 50
    • 13844272191 scopus 로고    scopus 로고
    • Hypoxia-induced increase in soluble Flt-1 production correlates with enhanced oxidative stress in trophoblast cells from the human placenta
    • DOI 10.1016/j.placenta.2004.05.004, PII S0143400404001468
    • H. Li, B. Gu, Y. Zhang, D.F. Lewis, and Y. Wang Hypoxia-induced increase in soluble Flt-1 production correlates with enhanced oxidative stress in trophoblast cells from the human placenta Placenta 26 2005 210 217 (Pubitemid 40247009)
    • (2005) Placenta , vol.26 , Issue.2-3 , pp. 210-217
    • Li, H.1    Gu, B.2    Zhang, Y.3    Lewis, D.F.4    Wang, Y.5
  • 51
    • 4544272023 scopus 로고    scopus 로고
    • The heme oxygenase system: Past, present, and future
    • DOI 10.1089/ars.2004.6.797
    • M.D. Maines The heme oxygenase system: past, present, and future Antioxid. Redox Signaling 6 2004 797 801 (Pubitemid 39237931)
    • (2004) Antioxidants and Redox Signaling , vol.6 , Issue.5 , pp. 797-801
    • Maines, M.D.1
  • 52
    • 84866944599 scopus 로고    scopus 로고
    • Heme oxygenase and ocular disease: A review of the literature
    • J. Zhao, S. Tan, F. Liu, Y. Zhang, M. Su, and D. Sun Heme oxygenase and ocular disease: a review of the literature Curr. Eye Res. 37 2012 955 960
    • (2012) Curr. Eye Res. , vol.37 , pp. 955-960
    • Zhao, J.1    Tan, S.2    Liu, F.3    Zhang, Y.4    Su, M.5    Sun, D.6
  • 53
    • 77950509320 scopus 로고    scopus 로고
    • Heme-arginate suppresses phospholipase C and oxidative stress in the mesenteric arterioles of mineralcorticoid-induced hypertensive rats
    • J.F. Ndisang, and A. Jadhav Heme-arginate suppresses phospholipase C and oxidative stress in the mesenteric arterioles of mineralcorticoid-induced hypertensive rats Hypertens. Res. 33 2010 338 347
    • (2010) Hypertens. Res. , vol.33 , pp. 338-347
    • Ndisang, J.F.1    Jadhav, A.2
  • 54
    • 84860864996 scopus 로고    scopus 로고
    • Curcumin protects retinal pigment epithelial cells against oxidative stress via induction of heme oxygenase-1 expression and reduction of reactive oxygen
    • J.M. Woo, D.Y. Shin, S.J. Lee, Y. Joe, M. Zheng, J.H. Yim, Z. Callaway, and H.T. Chung Curcumin protects retinal pigment epithelial cells against oxidative stress via induction of heme oxygenase-1 expression and reduction of reactive oxygen Mol. Vision 18 2012 901 908
    • (2012) Mol. Vision , vol.18 , pp. 901-908
    • Woo, J.M.1    Shin, D.Y.2    Lee, S.J.3    Joe, Y.4    Zheng, M.5    Yim, J.H.6    Callaway, Z.7    Chung, H.T.8
  • 55
    • 77950519283 scopus 로고    scopus 로고
    • Cigarette smoking, oxidative stress, the anti-oxidant response through Nrf2 signaling, and age-related macular degeneration
    • M. Cano, R. Thimmalappula, M. Fujihara, N. Nagai, M. Sporn, A.L. Wang, A.H. Neufeld, S. Biswal, and J.T. Handa Cigarette smoking, oxidative stress, the anti-oxidant response through Nrf2 signaling, and age-related macular degeneration Vision Res. 50 2010 652 664
    • (2010) Vision Res. , vol.50 , pp. 652-664
    • Cano, M.1    Thimmalappula, R.2    Fujihara, M.3    Nagai, N.4    Sporn, M.5    Wang, A.L.6    Neufeld, A.H.7    Biswal, S.8    Handa, J.T.9
  • 56
    • 84855218747 scopus 로고    scopus 로고
    • Reactive oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in sulforaphane-treated human mesothelioma MSTO-211H cells
    • Y.J. Lee, H.Y. Jeong, Y.B. Kim, S.Y. Won, J.H. Shim, M.K. Cho, H.S. Nam, and S.H. Lee Reactive oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in sulforaphane-treated human mesothelioma MSTO-211H cells Food Chem. Toxicol. 50 2012 116 123
    • (2012) Food Chem. Toxicol. , vol.50 , pp. 116-123
    • Lee, Y.J.1    Jeong, H.Y.2    Kim, Y.B.3    Won, S.Y.4    Shim, J.H.5    Cho, M.K.6    Nam, H.S.7    Lee, S.H.8
  • 57
    • 84883202650 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa pyocyanin activates NRF2-ARE-mediated transcriptional response via the ROS-EGFR-PI3K-AKT/MEK-ERK MAP kinase signaling in pulmonary epithelial cells
    • Y. Xu, C. Duan, Z. Kuang, Y. Hao, J.L. Jeffries, and G.W. Lau Pseudomonas aeruginosa pyocyanin activates NRF2-ARE-mediated transcriptional response via the ROS-EGFR-PI3K-AKT/MEK-ERK MAP kinase signaling in pulmonary epithelial cells PLoS One 8 2013 e72528
    • (2013) PLoS One , vol.8 , pp. 72528
    • Xu, Y.1    Duan, C.2    Kuang, Z.3    Hao, Y.4    Jeffries, J.L.5    Lau, G.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.