Tumor necrosis factor-alpha (TNF-α)-mediated in vitro human retinal pigment epithelial (RPE) cell migration mainly requires Akt/mTOR complex 1 (mTORC1), but not mTOR complex 2 (mTORC2) signaling

European Journal of Cell Biology

Volumn 91, Issue 9, 2012, Pages 728-737

  Liu, Yuan ^a   Cao, Guo Fan ^a   Xue, Jinsong ^a   Wan, Jerry ^b   Wan, Yinsheng ^b   Jiang, Qing ^a   Yao, Jin ^a  

^a First Affiliated Hospital of Nanjing Medical University   (China)

^b PROVIDENCE COLLEGE   (United States)

Author keywords

Akt mTOR signaling; Proliferative vitreoretinopathy (PVR); RPE cell migration; TNF

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; RAPAMYCIN; RHEB PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RNA INTERFERENCE; SIGNAL TRANSDUCTION; VITREORETINOPATHY;

CELL LINE; CELL MOVEMENT; HUMANS; MULTIPROTEIN COMPLEXES; PROTEINS; RETINAL PIGMENT EPITHELIUM; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84861952859     PISSN: 01719335     EISSN: 16181298     Source Type: Journal    
DOI: 10.1016/j.ejcb.2012.03.008     Document Type: Article

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