-
1
-
-
0030685825
-
IKK-1 and IKK-2: Cytokine-activated IκB kinases essential for NF-κB activation
-
DOI 10.1126/science.278.5339.860
-
F. Mercurio, H. Zhu, B.W. Murray, A. Shevchenko, B.L. Bennett, and J. Li IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation Science 278 1997 860 866 (Pubitemid 27467923)
-
(1997)
Science
, vol.278
, Issue.5339
, pp. 860-866
-
-
Mercurio, F.1
Zhu, H.2
Murray, B.W.3
Shevchenko, A.4
Bennett, B.L.5
Li, J.W.6
Young, D.B.7
Barbosa, M.8
Mann, M.9
Manning, A.10
Rao, A.11
-
2
-
-
0033595893
-
How NF-kappaB is activated: The role of the IkappaB kinase (IKK) complex
-
M. Karin How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex Oncogene 18 1999 6867 6874
-
(1999)
Oncogene
, vol.18
, pp. 6867-6874
-
-
Karin, M.1
-
3
-
-
33750355695
-
IKKβ inhibition protects against bone and cartilage destruction in a rat model of rheumatoid arthritis
-
DOI 10.1002/art.22081
-
L. Schopf, A. Savinainen, K. Anderson, J. Kujawa, M. DuPont, and M. Silva IKKbeta inhibition protects against bone and cartilage destruction in a rat model of rheumatoid arthritis Arthritis Rheum 54 2006 3163 3173 (Pubitemid 44622087)
-
(2006)
Arthritis and Rheumatism
, vol.54
, Issue.10
, pp. 3163-3173
-
-
Schopf, L.1
Savinainen, A.2
Anderson, K.3
Kujawa, J.4
DuPont, M.5
Silva, M.6
Siebert, E.7
Chandra, S.8
Morgan, J.9
Gangurde, P.10
Wen, D.11
Lane, J.12
Xu, Y.13
Hepperle, M.14
Harriman, G.15
Ocain, T.16
Jaffee, B.17
-
4
-
-
38449110152
-
Cutting edge: The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis
-
W. Shibata, S. Maeda, Y. Hikiba, A. Yanai, T. Ohmae, and K. Sakamoto Cutting edge: the IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis J Immunol 179 2007 2681 2685
-
(2007)
J Immunol
, vol.179
, pp. 2681-2685
-
-
Shibata, W.1
Maeda, S.2
Hikiba, Y.3
Yanai, A.4
Ohmae, T.5
Sakamoto, K.6
-
5
-
-
70350129602
-
Progress towards the development of anti-inflammatory inhibitors of IKKbeta
-
P. Bamborough, J.F. Callahan, J.A. Christopher, J.K. Kerns, J. Liddle, and D.D. Miller Progress towards the development of anti-inflammatory inhibitors of IKKbeta Curr Top Med Chem 9 2009 623 639
-
(2009)
Curr Top Med Chem
, vol.9
, pp. 623-639
-
-
Bamborough, P.1
Callahan, J.F.2
Christopher, J.A.3
Kerns, J.K.4
Liddle, J.5
Miller, D.D.6
-
6
-
-
34547875777
-
Use of herbal preparations in the treatment of oxidant-mediated inflammatory disorders
-
DOI 10.1016/j.ctim.2006.06.005, PII S0965229906000689
-
M. Kaplan, E.A. Mutlu, M. Benson, J.Z. Fields, A. Banan, and A. Keshavarzian Use of herbal preparations in the treatment of oxidant-mediated inflammatory disorders Complement Ther Med 15 2007 207 216 (Pubitemid 47250488)
-
(2007)
Complementary Therapies in Medicine
, vol.15
, Issue.3
, pp. 207-216
-
-
Kaplan, M.1
Mutlu, E.A.2
Benson, M.3
Fields, J.Z.4
Banan, A.5
Keshavarzian, A.6
-
7
-
-
69549115198
-
In search of antioxidants and anti-atherosclerotic agents from herbal medicines
-
M.S. Shiao, J.J. Chiu, B.W. Chang, J. Wang, W.P. Jen, and Y.J. Wu In search of antioxidants and anti-atherosclerotic agents from herbal medicines Biofactors 34 2008 147 157
-
(2008)
Biofactors
, vol.34
, pp. 147-157
-
-
Shiao, M.S.1
Chiu, J.J.2
Chang, B.W.3
Wang, J.4
Jen, W.P.5
Wu, Y.J.6
-
8
-
-
0346059348
-
Tanshinone IIA from Salvia miltiorrhiza Inhibits Inducible Nitric Oxide Synthase Expression and Production of TNF-α, IL-1β and IL-6 in Activated RAW 264.7 Cells
-
DOI 10.1055/s-2003-45157
-
S.I. Jang, S.I. Jeong, K.J. Kim, H.J. Kim, H.H. Yu, and R. Park Tanshinone IIA from Salvia miltiorrhiza inhibits inducible nitric oxide synthase expression and production of TNF-alpha, IL-1beta and IL-6 in activated RAW 264.7 cells Planta Med 69 2003 1057 1059 (Pubitemid 38064700)
-
(2003)
Planta Medica
, vol.69
, Issue.11
, pp. 1057-1059
-
-
Jang, S.-I.1
Jeong, S.-I.2
Kim, K.-J.3
Kim, H.-J.4
Yu, H.-H.5
Park, R.6
Kim, H.-M.7
You, Y.-O.8
-
9
-
-
22544469986
-
Aqueous extract of Salvia miltiorrhiza attenuates increased endothelial permeability induced by tumor necrosis factor-α
-
DOI 10.1016/j.intimp.2005.05.005, PII S156757690500130X
-
M. Ding, T.X. Ye, G.R. Zhao, Y.J. Yuan, and Z.X. Guo Aqueous extract of Salvia miltiorrhiza attenuates increased endothelial permeability induced by tumor necrosis factor-alpha Int Immunopharmacol 5 2005 1641 1651 (Pubitemid 41019435)
-
(2005)
International Immunopharmacology
, vol.5
, Issue.11
, pp. 1641-1651
-
-
Ding, M.1
Ye, T.-X.2
Zhao, G.-R.3
Yuan, Y.-J.4
Guo, Z.-X.5
-
10
-
-
67349179780
-
Effect of Salvia miltiorrhizae on the expressions of TLR4 protein in the liver of rats with SAP or OJ
-
X. Zhang, D. Liu, D. Wu, C. Zhu, J. Ye, and K. Wang Effect of Salvia miltiorrhizae on the expressions of TLR4 protein in the liver of rats with SAP or OJ Inflammation 32 2009 151 162
-
(2009)
Inflammation
, vol.32
, pp. 151-162
-
-
Zhang, X.1
Liu, D.2
Wu, D.3
Zhu, C.4
Ye, J.5
Wang, K.6
-
11
-
-
0026601262
-
Protective action of seven natural phenolic compounds against peroxidative damage to biomembranes
-
G.T. Liu, T.M. Zhang, B.E. Wang, and Y.W. Wang Protective action of seven natural phenolic compounds against peroxidative damage to biomembranes Biochem Pharmacol 43 1992 147 152
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 147-152
-
-
Liu, G.T.1
Zhang, T.M.2
Wang, B.E.3
Wang, Y.W.4
-
12
-
-
0027456480
-
Demonstration of the myocardial salvage effect of lithospermic acid B isolated from the aqueous extract of Salvia miltiorrhiza
-
K.P. Fung, L.H. Zeng, J. Wu, H.N. Wong, C.M. Lee, and P.M. Hon Demonstration of the myocardial salvage effect of lithospermic acid B isolated from the aqueous extract of Salvia miltiorrhiza Life Sci 52 1993 PL239 PL244
-
(1993)
Life Sci
, vol.52
-
-
Fung, K.P.1
Zeng, L.H.2
Wu, J.3
Wong, H.N.4
Lee, C.M.5
Hon, P.M.6
-
13
-
-
77954128851
-
Isolation of salvianolic acid A, a minor phenolic carboxylic acid of Salvia miltiorrhiza
-
L. Lu, H. Zhang, Y. Qian, and Y. Yuan Isolation of salvianolic acid A, a minor phenolic carboxylic acid of Salvia miltiorrhiza Nat Prod Commun 5 2010 805 808
-
(2010)
Nat Prod Commun
, vol.5
, pp. 805-808
-
-
Lu, L.1
Zhang, H.2
Qian, Y.3
Yuan, Y.4
-
14
-
-
70249126166
-
Effect of salvianolic acid A on vascular reactivity of streptozotocin-induced diabetic rats
-
S.B. Wang, X.Y. Yang, S. Tian, H.G. Yang, and G.H. Du Effect of salvianolic acid A on vascular reactivity of streptozotocin-induced diabetic rats Life Sci 85 2009 499 504
-
(2009)
Life Sci
, vol.85
, pp. 499-504
-
-
Wang, S.B.1
Yang, X.Y.2
Tian, S.3
Yang, H.G.4
Du, G.H.5
-
15
-
-
77953120701
-
Antiplatelet and antithrombotic activities of salvianolic acid A
-
H.Y. Fan, F.H. Fu, M.Y. Yang, H. Xu, A.H. Zhang, and K. Liu Antiplatelet and antithrombotic activities of salvianolic acid A Thromb Res 126 2010 e17 e22
-
(2010)
Thromb Res
, vol.126
-
-
Fan, H.Y.1
Fu, F.H.2
Yang, M.Y.3
Xu, H.4
Zhang, A.H.5
Liu, K.6
-
16
-
-
77957919100
-
Salvianolic acid A displays cardioprotective effects in in vitro models of heart hypoxia/reoxygenation injury
-
Y.Q. Zhang, Y. Tang, A.L. Wu, and H.B. Zhu Salvianolic acid A displays cardioprotective effects in in vitro models of heart hypoxia/reoxygenation injury J Asian Nat Prod Res 12 2010 899 915
-
(2010)
J Asian Nat Prod Res
, vol.12
, pp. 899-915
-
-
Zhang, Y.Q.1
Tang, Y.2
Wu, A.L.3
Zhu, H.B.4
-
17
-
-
22344451396
-
Salvia miltiorrhiza water-soluble extract, but not its constituent salvianolic acid B, abrogates LPS-induced NF-κB signalling in intestinal epithelial cells
-
DOI 10.1111/j.1365-2249.2005.02844.x
-
J.S. Kim, A.S. Narula, and C. Jobin Salvia miltiorrhiza water-soluble extract, but not its constituent salvianolic acid B, abrogates LPS-induced NF-kappaB signalling in intestinal epithelial cells Clin Exp Immunol 141 2005 288 297 (Pubitemid 41003353)
-
(2005)
Clinical and Experimental Immunology
, vol.141
, Issue.2
, pp. 288-297
-
-
Kim, J.S.1
Narula, A.S.2
Jobin, C.3
-
18
-
-
0041355495
-
A selective IKK-2 inhibitor blocks NF-κB-dependent gene expression in interleukin-1β-stimulated synovial fibroblasts
-
DOI 10.1074/jbc.M211439200
-
N. Kishore, C. Sommers, S. Mathialagan, J. Guzova, M. Yao, and S. Hauser A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts J Biol Chem 278 2003 32861 32871 (Pubitemid 37055728)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.35
, pp. 32861-32871
-
-
Kishore, N.1
Sommers, C.2
Mathialagan, S.3
Guzova, J.4
Yao, M.5
Hauser, S.6
Huynh, K.7
Bonar, S.8
Mielke, C.9
Albee, L.10
Weier, R.11
Graneto, M.12
Hanau, C.13
Perry, T.14
Tripp, C.S.15
-
19
-
-
78349278099
-
Identification of novel scaffolds for IκB kinase beta inhibitor via a high-throughput screening TR-FRET assay
-
K.S. Oh, S. Lee, J.K. Choi, and B.H. Lee Identification of novel scaffolds for IκB kinase beta inhibitor via a high-throughput screening TR-FRET assay Comb Chem High Throughput Screen 13 2010 790 797
-
(2010)
Comb Chem High Throughput Screen
, vol.13
, pp. 790-797
-
-
Oh, K.S.1
Lee, S.2
Choi, J.K.3
Lee, B.H.4
-
20
-
-
0027527363
-
A fluorometric assay for the measurement of nitrite in biological samples
-
DOI 10.1006/abio.1993.1449
-
T.P. Misko, R.J. Schilling, D. Salvemini, W.M. Moore, and M.G. Currie A fluorometric assay for the measurement of nitrite in biological samples Anal Biochem 214 1993 11 16 (Pubitemid 23300346)
-
(1993)
Analytical Biochemistry
, vol.214
, Issue.1
, pp. 11-16
-
-
Misko, T.P.1
Schilling, R.J.2
Salvemini, D.3
Moore, W.M.4
Currie, M.G.5
-
21
-
-
67849103759
-
IC50-to-Ki: A web-based tool for converting IC50 to Ki values for inhibitors of enzyme activity and ligand binding
-
R.Z. Cer, U. Mudunuri, R. Stephens, and F.J. Lebeda IC50-to-Ki: a web-based tool for converting IC50 to Ki values for inhibitors of enzyme activity and ligand binding Nucleic Acids Res 37 2009 W441 W445
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Cer, R.Z.1
Mudunuri, U.2
Stephens, R.3
Lebeda, F.J.4
-
22
-
-
27844511101
-
Danshen: An overview of its chemistry, pharmacology, pharmacokinetics, and clinical use
-
DOI 10.1177/0091270005282630
-
L. Zhou, Z. Zuo, and M.S. Chow Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use J Clin Pharmacol 45 2005 1345 1359 (Pubitemid 41643896)
-
(2005)
Journal of Clinical Pharmacology
, vol.45
, Issue.12
, pp. 1345-1359
-
-
Zhou, L.1
Zuo, Z.2
Chow, M.S.S.3
-
23
-
-
22944457184
-
Nitric oxide production and signaling in inflammation
-
DOI 10.2174/1568010054526359
-
R. Korhonen, A. Lahti, H. Kankaanranta, and E. Moilanen Nitric oxide production and signaling in inflammation Curr Drug Targets Inflamm Allergy 4 2005 471 479 (Pubitemid 41052412)
-
(2005)
Current Drug Targets: Inflammation and Allergy
, vol.4
, Issue.4
, pp. 471-479
-
-
Korhonen, R.1
Lahti, A.2
Kankaanranta, H.3
Moilanen, E.4
-
24
-
-
34548766145
-
Prostaglandin receptor signaling in disease
-
DOI 10.1100/tsw.2007.182
-
T. Matsuoka, and S. Narumiya Prostaglandin receptor signaling in disease Sci World J 7 2007 1329 1347 (Pubitemid 47435437)
-
(2007)
TheScientificWorldJournal
, vol.7
, pp. 1329-1347
-
-
Matsuoka, T.1
Narumiya, S.2
-
25
-
-
0030623646
-
Regulation of NF-kappa B and disease control: Identification of a novel serine kinase and thioredoxin as effectors for signal transduction pathway for NF-kappa B activation
-
T. Okamoto, S. Sakurada, J.P. Yang, and J.P. Merin Regulation of NF-kappa B and disease control: identification of a novel serine kinase and thioredoxin as effectors for signal transduction pathway for NF-kappa B activation Curr Top Cell Regul 35 1997 149 161
-
(1997)
Curr Top Cell Regul
, vol.35
, pp. 149-161
-
-
Okamoto, T.1
Sakurada, S.2
Yang, J.P.3
Merin, J.P.4
-
26
-
-
0036234459
-
Missing pieces in the NF-kappaB puzzle
-
S. Ghosh, and M. Karin Missing pieces in the NF-kappaB puzzle Cell 109 Suppl 2002 S81 S96
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
Ghosh, S.1
Karin, M.2
-
27
-
-
0030992159
-
Discovery and analysis of inflammatory disease-related genes using cDNA microarrays
-
DOI 10.1073/pnas.94.6.2150
-
R.A. Heller, M. Schena, A. Chai, D. Shalon, T. Bedilion, and J. Gilmore Discovery and analysis of inflammatory disease-related genes using cDNA microarrays Proc Natl Acad Sci USA 94 1997 2150 2155 (Pubitemid 27136843)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.6
, pp. 2150-2155
-
-
Heller, R.A.1
Schena, M.2
Chai, A.3
Shalon, D.4
Bedilion, T.5
Gilmore, J.6
Woolley, D.E.7
Davis, R.W.8
-
28
-
-
0034578521
-
Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IkappaB kinase and NFkappaB activation in macrophages
-
M.H. Pan, S.Y. Lin-Shiau, and J.K. Lin Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IkappaB kinase and NFkappaB activation in macrophages Biochem Pharmacol 60 2000 1665 1676
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1665-1676
-
-
Pan, M.H.1
Lin-Shiau, S.Y.2
Lin, J.K.3
|