Effects of salvianolic acid A on oxygen radicals released by rat neutrophils and on neutrophil function

Biochemical Pharmacology

Volumn 51, Issue 9, 1996, Pages 1237-1241

  Lin, Tong Jun ^a   Zhang, Ke Jian ^a   Liu, Geng Tao ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

chemotaxis; free calcium; free radicals; neutrophils; phagocytosis; salvianolic acid A

Indexed keywords

ANTIOXIDANT; CALCIUM; CYCLIC NUCLEOTIDE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; HYDROGEN PEROXIDE; OXYGEN RADICAL; PHORBOL 13 ACETATE 12 MYRISTATE; SALVIANOLIC ACID A; SCAVENGER; SCOPOLETIN; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CHEMOTAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; LEUKOCYTE FUNCTION; MALE; NEUTROPHIL; NITROBLUE TETRAZOLIUM TEST; NONHUMAN; OXIDATION REDUCTION STATE; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT; SALVIA MILTIORRHIZA;

EID: 0029920512     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00067-6     Document Type: Article

References (17)

1. Chen WZ, Pharmacology of Salvia miltiorrhiza. Acta Pharm Sin 19: 876-880, 1984.
2. Li LN, Tan R and Chen WM, Salvianolic acid A, a new depside from roots of Salvia miltiorrhiza. Planta Med 50: 227-228, 1984.
3. Liu GT, Zhang TM, Wang BE and Wang YW, Protective action of seven natural phenolic compounds against peroxidative damage to biomembranes. Biochem Pharmacol 43: 147-152, 1992.
4. Lin TJ and Liu GT, Protective effect of salvianolic acid A on heart and liver mitochondria injury induced by oxygen radicals in rats. Chin J Pharmacol Toxicol 5: 276-281, 1991.
5. Lin TJ, Liu GT, Liu Y and Xu GZ, Protection by salvianolic acid A against adriamycin toxicity on rat heart mitochondria. Free Radic Biol Med 12: 347-351, 1992.
6. Mitsos SE, Askew TE, Fantone JC, Kunkel SL, Abrams GD, Schork A and Lucchesi BR, Protective effects of N-2-mercaptopropionyl glycine against myocardial reperfusion injury after neutrophil depletion in the dog: Evidence for the role of the intracellular-derived free radicals. Circulation 73: 1077-1086, 1986.
7. Simpson PJ, Mickelson JK and Lucchesi BR, Free radical scavengers in myocardial ischemia. Fedn Proc 46: 2413-2421, 1987.
8. Bautisca AP, Meszaros K, Bojta J and Spitzer JJ, Superoxide anion generation in the liver during the early stage of endotoxemia in rats. J Leukoc Biol 48: 123-128, 1990.
9. McCord JM, Free radical and myocardial ischemia: Overview and outlook. Free Radic Biol Med 4: 9-14, 1988.
10. Stossel TP, Evaluation of opsonic and leukocyte function with a spectrophotometric test in patients with infection and with phagocytic disorders. Blood 42: 121-130, 1973.
11. Onodra T and Ashraf M, Detection of hydroxyl radicals in the post-ischemic reperfused heart using salicylate as a trapping agent. J Mol Cell Cardiol 23: 365-370, 1991.
12. Nathan CF, Brukner LH, Silverstein SC and Cohn ZA, Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide. J Exp Med 149: 84-99, 1979.
13. Nelson RD, Quie PG and Simmons RL, Chemotaxis under agarose: A new and simple method for measuring chemotaxis and spontaneous migration of human polymorphonuclear leukocytes and monocytes. J Immunol 115: 1650-1656, 1975.
14. 5 on calcium mobilization in human neutrophils. Prostaglandins Leukot Essent Fatty Acids 34: 47-50, 1988.
15. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260: 3440-3450, 1985.
16. Klebanoff SJ and Clark RA, Phagocytosis. In: The Neutrophil: Function and Clinical Disorders (Eds. Klebanoff SJ and Clark RA), pp. 163-216. North-Holland Publishing Co., Amsterdam, 1978.
17. Zhang KJ, Lin TJ and Liu GT, Effect of schisanhenol on the function and surface shape of rat neutrophils, Acta Pharmacol Sin 16: 234-238, 1995.