Measurement of the unfolded protein response to investigate its role in adipogenesis and obesity

Methods in Enzymology

Volumn 538, Issue , 2014, Pages 135-150

  Han, Jaeseok ^a   Kaufman, Randal J ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

Adipocyte; Atf6 ; eIF2 ; ER stress; IRE1 ; Unfolded protein response (UPR)

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; ACTIVATING TRANSCRIPTION FACTOR 6ALPHA; CALCIUM; GADD34 PROTEIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; INSULIN; PHOSPHOTRANSFERASE; PROTEIN IRE1; PROTEIN IRE1ALPHA; PROTEIN KINASE LIKE ER KINASE; TETRACYCLINE; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ADIPOCYTE; ADIPOGENESIS; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CONTROLLED STUDY; DIMERIZATION; EMBRYO; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; EXTRACELLULAR SPACE; GAIN OF FUNCTION MUTATION; GENE DELETION; GENE EXPRESSION; HOMEOSTASIS; INSULIN RESISTANCE; KNOCKOUT GENE; KNOCKOUT MOUSE; LIPID STORAGE; LIPOGENESIS; LOSS OF FUNCTION MUTATION; METABOLIC SYNDROME X; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PATHOGENESIS; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; RNA SPLICING; SIGNAL TRANSDUCTION; TRANSGENE; UNFOLDED PROTEIN RESPONSE;

ADIPOCYTE; ATF6Α; EIF2Α; ER STRESS; IRE1Α; UNFOLDED PROTEIN RESPONSE (UPR);

3T3-L1 CELLS; ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; ADIPOCYTES; ADIPOGENESIS; ANIMALS; EIF-2 KINASE; ENDORIBONUCLEASES; ENZYME ACTIVATION; ENZYME ASSAYS; GENE EXPRESSION REGULATION; GENETIC TECHNIQUES; HUMANS; MICE; OBESITY; PHOSPHORYLATION; PROTEIN PHOSPHATASE 1; PROTEIN-SERINE-THREONINE KINASES; TRANSCRIPTION FACTOR CHOP; UNFOLDED PROTEIN RESPONSE;

EID: 84894091792     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/B978-0-12-800280-3.00008-6     Document Type: Chapter

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