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Volumn 2013, Issue , 2013, Pages

The effect of inflammatory cytokines in alcoholic liver disease

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CHEMOKINE; CYTOKINE; INFLAMMASOME; INTERLEUKIN 10; INTERLEUKIN 6; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 84893863556     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2013/495156     Document Type: Review
Times cited : (194)

References (113)
  • 1
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediators of hepatic steatosis and liver injury
    • DOI 10.1172/JCI200422422
    • Browning J. D., Horton J. D., Molecular mediators of hepatic steatosis and liver injury. Journal of Clinical Investigation 2004 114 2 147 152 2-s2.0-4043077961 10.1172/JCI200422422 (Pubitemid 39071617)
    • (2004) Journal of Clinical Investigation , vol.114 , Issue.2 , pp. 147-152
    • Browning, J.D.1    Horton, J.D.2
  • 2
    • 0023025701 scopus 로고
    • Histologic spectrum of alcoholic liver disease
    • MacSween R. N. M., Burt A. D., Histologic spectrum of alcoholic liver disease. Seminars in Liver Disease 1986 6 3 221 232 2-s2.0-0023025701 (Pubitemid 17203551)
    • (1986) Seminars in Liver Disease , vol.6 , Issue.3 , pp. 221-232
    • MacSween, R.N.M.1    Burt, A.D.2
  • 3
    • 0346729708 scopus 로고    scopus 로고
    • Pathogenesis and management of alcoholic hepatitis
    • DOI 10.1046/j.1440-1746.2003.03217.x
    • Haber P. S., Warner R., Seth D., Gorrell M. D., McCaughan G. W., Pathogenesis and management of alcoholic hepatitis. Journal of Gastroenterology and Hepatology 2003 18 12 1332 1344 2-s2.0-0346729708 10.1046/j.1440-1746.2003. 03217.x (Pubitemid 38045845)
    • (2003) Journal of Gastroenterology and Hepatology , vol.18 , Issue.12 , pp. 1332-1344
    • Haber, P.S.1    Warner, R.2    Seth, D.3    Gorrell, M.D.4    McCaughan, G.W.5
  • 4
  • 6
    • 0030716183 scopus 로고    scopus 로고
    • Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat
    • Iimuro Y., Gallucci R. M., Luster M., Kono H., Thurman R. G., Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat. Hepatology 1997 26 6 1530 1537 2-s2.0-0030716183 (Pubitemid 27520019)
    • (1997) Hepatology , vol.26 , Issue.6 , pp. 1530-1537
    • Iimuro, Y.1    Gallucci, R.M.2    Luster, M.3    Kono, H.4    Thurman, R.G.5
  • 7
    • 2642553874 scopus 로고    scopus 로고
    • Recent advances in alcoholic liver disease. I. Role of intestinal permeability and endotoxemia in alcoholic liver disease
    • DOI 10.1152/ajpgi.00006.2004
    • Rao R. K., Seth A., Sheth P., Recent advances in alcoholic liver disease. I. Role of intestinal permeability and endotoxemia in alcoholic liver disease. The American Journal of Physiology: Gastrointestinal and Liver Physiology 2004 286 6 G881 G884 2-s2.0-2642553874 10.1152/ajpgi.00006.2004 (Pubitemid 38715649)
    • (2004) American Journal of Physiology - Gastrointestinal and Liver Physiology , vol.286
    • Rao, R.K.1    Seth, A.2    Sheth, P.3
  • 8
    • 33747605552 scopus 로고    scopus 로고
    • Regulation of Kupffer cell activity during chronic ethanol exposure: Role of adiponectin
    • DOI 10.1111/j.1440-1746.2006.04580.x
    • Park P.-H., Thakur V., Pritchard M. T., McMullen M. R., Nagy L. E., Regulation of Kupffer cell activity during chronic ethanol exposure: role of adiponectin. Journal of Gastroenterology and Hepatology 2006 21 3 S30 S33 2-s2.0-33747605552 10.1111/j.1440-1746.2006.04580.x (Pubitemid 44266546)
    • (2006) Journal of Gastroenterology and Hepatology , vol.21 , Issue.SUPPL. 3
    • Park, P.-H.1    Thakur, V.2    Pritchard, M.T.3    McMullen, M.R.4    Nagy, L.E.5
  • 9
    • 0142151769 scopus 로고    scopus 로고
    • Kupffer Cell Engulfment of Apoptotic Bodies Stimulates Death Ligand and Cytokine Expression
    • DOI 10.1053/jhep.2003.50472
    • Canbay A., Feldstein A. E., Higuchi H., Werneburg N., Grambihler A., Bronk S. F., Gores G. J., Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression. Hepatology 2003 38 5 1188 1198 2-s2.0-0142151769 10.1053/jhep.2003.50472 (Pubitemid 37314827)
    • (2003) Hepatology , vol.38 , Issue.5 , pp. 1188-1198
    • Canbay, A.1    Feldstein, A.E.2    Higuchi, H.3    Werneburg, N.4    Grambihler, A.5    Bronk, S.F.6    Gores, G.J.7
  • 10
    • 4143065802 scopus 로고    scopus 로고
    • Recent advances in alcoholic liver disease. IV. Dysregulated cytokine metabolism in alcoholic liver disease
    • DOI 10.1152/ajpgi.00171.2004
    • McClain C. J., Song Z., Barve S. S., Hill D. B., Deaciuc I., Recent advances in alcoholic liver disease. IV. Dysregulated cytokine metabolism in alcoholic liver disease. The American Journal of Physiology: Gastrointestinal and Liver Physiology 2004 287 3 G497 G502 2-s2.0-4143065802 10.1152/ajpgi.00171. 2004 (Pubitemid 39096613)
    • (2004) American Journal of Physiology - Gastrointestinal and Liver Physiology , vol.287
    • McClain, C.J.1    Song, Z.2    Barve, S.S.3    Hill, D.B.4    Deaciuc, I.5
  • 11
    • 0034676629 scopus 로고    scopus 로고
    • Cytokines in alcoholic and nonalcoholic steatohepatitis
    • 2-s2.0-0034676629 10.1056/NEJM200011163432007
    • Tilg H., Diehl A. M., Cytokines in alcoholic and nonalcoholic steatohepatitis. The New England Journal of Medicine 2000 343 20 1467 1467 2-s2.0-0034676629 10.1056/NEJM200011163432007
    • (2000) The New England Journal of Medicine , vol.343 , Issue.20 , pp. 1467-1467
    • Tilg, H.1    Diehl, A.M.2
  • 12
    • 32944463507 scopus 로고    scopus 로고
    • Cytokines, STATs and liver disease
    • 2-s2.0-32944463507
    • Gao B., Cytokines, STATs and liver disease. Cellular & Molecular Immunology 2005 2 2 92 100 2-s2.0-32944463507
    • (2005) Cellular & Molecular Immunology , vol.2 , Issue.2 , pp. 92-100
    • Gao, B.1
  • 13
    • 0021952111 scopus 로고
    • Aldehyde dehydrogenase in drosophila: Developmental and functional aspects
    • DOI 10.1016/0741-8329(85)90021-7
    • Garcin F., Lau You Hin G., Cote J., Aldehyde dehydrogenase in drosophila: developmental and functional aspects. Alcohol 1985 2 1 85 89 2-s2.0-0021952111 10.1016/0741-8329(85)90021-7 (Pubitemid 15119116)
    • (1985) Alcohol , vol.2 , Issue.1 , pp. 85-89
    • Garcin, F.1    Lau You Hin, G.2    Cote, J.3
  • 14
    • 0015333453 scopus 로고
    • The role of the hepatic microsomal ethanol oxidizing system (MEOS) for ethanol metabolism in vivo
    • 2-s2.0-0015333453
    • Lieber C. S., DeCarli L. M., The role of the hepatic microsomal ethanol oxidizing system (MEOS) for ethanol metabolism in vivo. Journal of Pharmacology and Experimental Therapeutics 1972 181 2 279 287 2-s2.0-0015333453
    • (1972) Journal of Pharmacology and Experimental Therapeutics , vol.181 , Issue.2 , pp. 279-287
    • Lieber, C.S.1    Decarli, L.M.2
  • 15
    • 0034595984 scopus 로고    scopus 로고
    • Molecular basis for the transport of cytochrome P450 2E1 to the plasma membrane
    • DOI 10.1074/jbc.M000957200
    • Neve E. P. A., Ingelman-Sundberg M., Molecular basis for the transport of cytochrome P450 2E1 to the plasma membrane. Journal of Biological Chemistry 2000 275 22 17130 17135 2-s2.0-0034595984 10.1074/jbc.M000957200 (Pubitemid 30398958)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.22 , pp. 17130-17135
    • Neve, E.P.A.1    Ingelman-Sundberg, M.2
  • 16
    • 0028261915 scopus 로고
    • Metabolic consequences of ethanol
    • Lieber C. S., Metabolic consequences of ethanol. The Endocrinologist 1994 4 2 127 139 2-s2.0-0028261915 (Pubitemid 24092473)
    • (1994) Endocrinologist , vol.4 , Issue.2 , pp. 127-139
    • Lieber, C.S.1
  • 17
    • 33750999322 scopus 로고    scopus 로고
    • Role of Kupffer cells in host defense and liver disease
    • DOI 10.1111/j.1478-3231.2006.01342.x
    • Bilzer M., Roggel F., Gerbes A. L., Role of Kupffer cells in host defense and liver disease. Liver International 2006 26 10 1175 1186 2-s2.0-33750999322 10.1111/j.1478-3231.2006.01342.x (Pubitemid 44741204)
    • (2006) Liver International , vol.26 , Issue.10 , pp. 1175-1186
    • Bilzer, M.1    Roggel, F.2    Gerbes, A.L.3
  • 18
    • 10844265570 scopus 로고    scopus 로고
    • Recent events in alcoholic liver disease: V. Effects of ethanol on liver regeneration
    • DOI 10.1152/ajpgi.00376.2004
    • Diehl A. M., Recent events in alcoholic liver disease: V. Effects of ethanol on liver regeneration. The American Journal of Physiology: Gastrointestinal and Liver Physiology 2005 288 1 G1 G6 2-s2.0-10844265570 10.1152/ajpgi.00376.2004 (Pubitemid 39665213)
    • (2005) American Journal of Physiology - Gastrointestinal and Liver Physiology , vol.288
    • Diehl, A.M.1
  • 19
    • 0027992143 scopus 로고
    • The role of tumor necrosis factor-α in acute endotoxin-induced hepatotoxicity in ethanol-fed rats
    • DOI 10.1016/0270-9139(94)90200-3
    • Hansen J., Cherwitz D. L., Allen J. I., The role of tumor necrosis factor- α in acute endotoxin-induced hepatotoxicity in ethanol-fed rats. Hepatology 1994 20 2 461 474 2-s2.0-0027992143 10.1016/0270-9139(94)90200-3 (Pubitemid 24233375)
    • (1994) Hepatology , vol.20 , Issue.2 , pp. 461-474
    • Hansen, J.1    Cherwitz, D.L.2    Allen, J.I.3
  • 20
    • 0032917769 scopus 로고    scopus 로고
    • Ethanol dissociates hormone-stimulated cAMP production from inhibition of TNF-α production in rat Kupffer cells
    • Aldred A., Nagy L. E., Ethanol dissociates hormone-stimulated cAMP production from inhibition of TNF- α production in rat Kupffer cells. The American Journal of Physiology: Gastrointestinal and Liver Physiology 1999 276 1 G98 G106 2-s2.0-0032917769 (Pubitemid 29063605)
    • (1999) American Journal of Physiology - Gastrointestinal and Liver Physiology , vol.276
    • Aldred, A.1    Nagy, L.E.2
  • 22
    • 63449086438 scopus 로고    scopus 로고
    • Innate immune reactivity of the liver in rats fed a choline-deficient L-amino-acid-defined diet
    • 2-s2.0-63449086438 10.3748/wjg.14.6655
    • Kawaratani H., Tsujimoto T., Kitazawa T., Kitade M., Yoshiji H., Uemura M., Fukui H., Innate immune reactivity of the liver in rats fed a choline-deficient L-amino-acid-defined diet. World Journal of Gastroenterology 2008 14 43 6655 6661 2-s2.0-63449086438 10.3748/wjg.14.6655
    • (2008) World Journal of Gastroenterology , vol.14 , Issue.43 , pp. 6655-6661
    • Kawaratani, H.1    Tsujimoto, T.2    Kitazawa, T.3    Kitade, M.4    Yoshiji, H.5    Uemura, M.6    Fukui, H.7
  • 23
    • 0035183475 scopus 로고    scopus 로고
    • Gene expression of tumor necrosis factor α and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients
    • DOI 10.1053/jhep.2001.29628
    • Crespo J., Cayoen A., Fernendez-Gil P., Hernndez-Guerra M., Mayorga M., Domnguez-Dez A., Fernndez-Escalante J. C., Pons-Romero F., Gene expression of tumor necrosis factor α and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients. Hepatology 2001 34 6 1158 1163 2-s2.0-0035183475 10.1053/jhep.2001.29628 (Pubitemid 33096588)
    • (2001) Hepatology , vol.34 , Issue.6 , pp. 1158-1163
    • Crespo, J.1    Cayoen, A.2    Fernendez-Gil, P.3    Hernndez-Guerra, M.4    Mayorga, M.5    Domnguez-Dez, A.6    Fernndez-Escalante, J.C.7    Pons-Romero, F.8
  • 25
    • 74849121386 scopus 로고    scopus 로고
    • Potential role of enhanced cytokinemia and plasma inhibitor on the decreased activity of plasma ADAMTS13 in patients with alcoholic hepatitis: Relationship to endotoxemia
    • 2-s2.0-74849121386 10.1111/j.1530-0277.2008.00850.x
    • Ishikawa M., Uemura M., Matsuyama T., Matsumoto M., Ishizashi H., Kato S., Morioka C., Fujimoto M., Kojima H., Yoshiji H., Tsujimoto T., Takimura C., Fujimura Y., Fukui H., Potential role of enhanced cytokinemia and plasma inhibitor on the decreased activity of plasma ADAMTS13 in patients with alcoholic hepatitis: relationship to endotoxemia. Alcoholism 2010 34 1 S25 S33 2-s2.0-74849121386 10.1111/j.1530-0277.2008.00850.x
    • (2010) Alcoholism , vol.34 , Issue.1
    • Ishikawa, M.1    Uemura, M.2    Matsuyama, T.3    Matsumoto, M.4    Ishizashi, H.5    Kato, S.6    Morioka, C.7    Fujimoto, M.8    Kojima, H.9    Yoshiji, H.10    Tsujimoto, T.11    Takimura, C.12    Fujimura, Y.13    Fukui, H.14
  • 27
    • 0034465251 scopus 로고    scopus 로고
    • Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: A double-blind, placebo-controlled trial
    • Akriviadis E., Botla R., Briggs W., Han S., Reynolds T., Shakil O., Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial. Gastroenterology 2000 119 6 1637 1648 2-s2.0-0034465251 (Pubitemid 32198689)
    • (2000) Gastroenterology , vol.119 , Issue.6 , pp. 1637-1648
    • Akriviadis, E.1    Botla, R.2    Briggs, W.3    Han, S.4    Reynolds, T.5    Shakil, O.6
  • 29
    • 79952856333 scopus 로고    scopus 로고
    • Therapeutic effects of cytokine modulator Y-40138 in the rat alcoholic liver disease model
    • 2-s2.0-79952856333 10.1111/j.1440-1746.2011.06658.x
    • Kawaratani H., Tsujimoto T., Kitazawa T., Yoshiji H., Uemura M., Fukui H., Therapeutic effects of cytokine modulator Y-40138 in the rat alcoholic liver disease model. Journal of Gastroenterology and Hepatology 2011 26 4 775 783 2-s2.0-79952856333 10.1111/j.1440-1746.2011.06658.x
    • (2011) Journal of Gastroenterology and Hepatology , vol.26 , Issue.4 , pp. 775-783
    • Kawaratani, H.1    Tsujimoto, T.2    Kitazawa, T.3    Yoshiji, H.4    Uemura, M.5    Fukui, H.6
  • 30
    • 0025845292 scopus 로고
    • Elevated plasma interleukin-6 and increased severity and mortality in alcoholic hepatitis
    • 2-s2.0-0025845292
    • Sheron N., Bird G., Goka J., Alexander G., Williams R., Elevated plasma interleukin-6 and increased severity and mortality in alcoholic hepatitis. Clinical and Experimental Immunology 1991 84 3 449 453 2-s2.0-0025845292
    • (1991) Clinical and Experimental Immunology , vol.84 , Issue.3 , pp. 449-453
    • Sheron, N.1    Bird, G.2    Goka, J.3    Alexander, G.4    Williams, R.5
  • 31
    • 0037011992 scopus 로고    scopus 로고
    • L proteins
    • DOI 10.1038/sj.onc.1205016
    • Hong F., Kim W.-H., Tian Z., Jaruga B., Ishac E., Shen X., Gao B., Elevated interleukin-6 during ethanol consumption acts as a potential endogenous protective cytokine against ethanol-induced apoptosis in the liver: involvement of induction of Bcl-2 and Bcl-xL proteins. Oncogene 2002 21 1 32 43 2-s2.0-0037011992 10.1038/sj.onc.1205016 (Pubitemid 34076376)
    • (2002) Oncogene , vol.21 , Issue.1 , pp. 32-43
    • Hong, F.1    Kim, W.-H.2    Tian, Z.3    Jaruga, B.4    Ishac, E.5    Shen, X.6    Gao, B.7
  • 32
    • 21344457230 scopus 로고    scopus 로고
    • Immune responses to ethanol metabolites and cytokine profiles differentiate alcoholics with or without liver disease
    • DOI 10.1111/j.1572-0241.2005.41509.x
    • Latvala J., Hietala J., Koivisto H., Järvi K., Anttila P., Niemelä O., Immune responses to ethanol metabolites and cytokine profiles differentiate alcoholics with or without liver disease. American Journal of Gastroenterology 2005 100 6 1303 1310 2-s2.0-21344457230 10.1111/j.1572-0241. 2005.41509.x (Pubitemid 40904353)
    • (2005) American Journal of Gastroenterology , vol.100 , Issue.6 , pp. 1303-1310
    • Latvala, J.1    Hietala, J.2    Koivisto, H.3    Jarvi, K.4    Anttila, P.5    Niemela, O.6
  • 33
    • 12744259191 scopus 로고    scopus 로고
    • IL-6-deficient mice are susceptible to ethanol-induced hepatic steatosis: IL-6 protects against ethanol-induced oxidative stress and mitochondrial permeability transition in the liver
    • 2-s2.0-12744259191
    • El-Assal O., Hong F., Kim W.-H., Radaeva S., Gao B., IL-6-deficient mice are susceptible to ethanol-induced hepatic steatosis: IL-6 protects against ethanol-induced oxidative stress and mitochondrial permeability transition in the liver. Cellular & molecular immunology 2004 1 3 205 211 2-s2.0-12744259191
    • (2004) Cellular & Molecular Immunology , vol.1 , Issue.3 , pp. 205-211
    • El-Assal, O.1    Hong, F.2    Kim, W.-H.3    Radaeva, S.4    Gao, B.5
  • 34
    • 78649614542 scopus 로고    scopus 로고
    • Interleukin-6 is an important mediator for mitochondrial DNA repair after alcoholic liver injury in mice
    • 2-s2.0-78649614542 10.1002/hep.23909
    • Zhang X., Tachibana S., Wang H., Hisada M., Williams G. M., Gao B., Sun Z., Interleukin-6 is an important mediator for mitochondrial DNA repair after alcoholic liver injury in mice. Hepatology 2010 52 6 2137 2147 2-s2.0-78649614542 10.1002/hep.23909
    • (2010) Hepatology , vol.52 , Issue.6 , pp. 2137-2147
    • Zhang, X.1    Tachibana, S.2    Wang, H.3    Hisada, M.4    Williams, G.M.5    Gao, B.6    Sun, Z.7
  • 35
    • 38949164424 scopus 로고    scopus 로고
    • Transgenic blockade of interleukin 6 transsignaling abrogates inflammation
    • DOI 10.1182/blood-2007-07-102137
    • Rabe B., Chalaris A., May U., Waetzig G. H., Seegert D., Williams A. S., Jones S. A., Rose-John S., Scheller J., Transgenic blockade of interleukin 6 transsignaling abrogates inflammation. Blood 2008 111 3 1021 1028 2-s2.0-38949164424 10.1182/blood-2007-07-102137 (Pubitemid 351213379)
    • (2008) Blood , vol.111 , Issue.3 , pp. 1021-1028
    • Rabe, B.1    Chalaris, A.2    May, U.3    Waetzig, G.H.4    Seegert, D.5    Williams, A.S.6    Jones, S.A.7    Rose-John, S.8    Scheller, J.9
  • 36
  • 37
    • 17144405680 scopus 로고    scopus 로고
    • Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma
    • DOI 10.1038/nri1589
    • Hawrylowicz C. M., O'Garra A., Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma. Nature Reviews Immunology 2005 5 4 271 283 2-s2.0-17144405680 10.1038/nri1589 (Pubitemid 40516153)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.4 , pp. 271-283
    • Hawrylowicz, C.M.1    O'Garra, A.2
  • 40
    • 0026094306 scopus 로고
    • Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes
    • 2-s2.0-0026094306
    • De Waal Malefyt R., Abrams J., Bennett B., Figdor C. G., De Vries J. E., Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. Journal of Experimental Medicine 1991 174 5 1209 1220 2-s2.0-0026094306
    • (1991) Journal of Experimental Medicine , vol.174 , Issue.5 , pp. 1209-1220
    • De Waal Malefyt, R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    De Vries, J.E.5
  • 42
    • 80052005701 scopus 로고    scopus 로고
    • Inflammation-associated interleukin-6/signal transducer and activator of transcription 3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in interleukin-10-deficient mice
    • 2-s2.0-80052005701 10.1002/hep.24517
    • Miller A. M., Wang H., Bertola A., Park O., Horiguchi N., Hwan Ki S., Yin S., Lafdil F., Gao B., Inflammation-associated interleukin-6/signal transducer and activator of transcription 3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in interleukin-10-deficient mice. Hepatology 2011 54 3 846 856 2-s2.0-80052005701 10.1002/hep.24517
    • (2011) Hepatology , vol.54 , Issue.3 , pp. 846-856
    • Miller, A.M.1    Wang, H.2    Bertola, A.3    Park, O.4    Horiguchi, N.5    Hwan Ki, S.6    Yin, S.7    Lafdil, F.8    Gao, B.9
  • 43
    • 0032862559 scopus 로고    scopus 로고
    • Activation of nuclear factor kappa B and cytokine imbalance in experimental alcoholic liver disease in the rat
    • DOI 10.1002/hep.510300402
    • Nanji A. A., Jokelainen K., Rahemtulla A., Miao L., Fogt F., Matsumoto H., Tahan S. R., Su G. L., Activation of nuclear factor kappa B and cytokine imbalance in experimental alcoholic liver disease in the rat. Hepatology 1999 30 4 934 943 2-s2.0-0032862559 10.1002/hep.510300402 (Pubitemid 29458282)
    • (1999) Hepatology , vol.30 , Issue.4 , pp. 934-943
    • Nanji, A.A.1    Jokelainen, K.2    Rahemtulla, A.3    Miao, L.4    Fogt, F.5    Matsumoto, H.6    Tahan, S.R.7    Su, G.L.8
  • 45
    • 34548125305 scopus 로고    scopus 로고
    • Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells
    • DOI 10.1038/ni1496, PII NI1496
    • Acosta-Rodriguez E. V., Napolitani G., Lanzavecchia A., Sallusto F., Interleukins 1 β and 6 but not transforming growth factor- β are essential for the differentiation of interleukin 17-producing human T helper cells. Nature Immunology 2007 8 9 942 949 2-s2.0-34548125305 10.1038/ni1496 (Pubitemid 47300008)
    • (2007) Nature Immunology , vol.8 , Issue.9 , pp. 942-949
    • Acosta-Rodriguez, E.V.1    Napolitani, G.2    Lanzavecchia, A.3    Sallusto, F.4
  • 46
    • 33847206969 scopus 로고    scopus 로고
    • IL-17 family cytokines and the expanding diversity of effector T cell lineages
    • DOI 10.1146/annurev.immunol.25.022106.141557
    • Weaver C. T., Hatton R. D., Mangan P. R., Harrington L. E., IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annual Review of Immunology 2007 25 821 852 2-s2.0-33847206969 10.1146/annurev.immunol.25. 022106.141557 (Pubitemid 46697925)
    • (2007) Annual Review of Immunology , vol.25 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3    Harrington, L.E.4
  • 47
    • 77957274840 scopus 로고    scopus 로고
    • Th17 cells and their associated cytokines in liver diseases
    • 2-s2.0-77957274840 10.1038/cmi.2010.5
    • Lafdil F., Miller A. M., Ki S. H., Gao B., Th17 cells and their associated cytokines in liver diseases. Cellular and Molecular Immunology 2010 7 4 250 254 2-s2.0-77957274840 10.1038/cmi.2010.5
    • (2010) Cellular and Molecular Immunology , vol.7 , Issue.4 , pp. 250-254
    • Lafdil, F.1    Miller, A.M.2    Ki, S.H.3    Gao, B.4
  • 49
    • 0027986662 scopus 로고
    • Markedly enhanced cytochrome P450 2E1 induction and lipid peroxidation is associated with severe liver injury in fish oil-ethanol-fed rats
    • DOI 10.1111/j.1530-0277.1994.tb00119.x
    • Nanji A. A., Zhao S., Sadrzadeh S. M. H., Dannenberg A. J., Tahan S. R., Waxman D. J., Markedly enhanced cytochrome P450 2E1 induction and lipid peroxidation is associated with severe liver injury in fish oil-ethanol-fed rats. Alcoholism 1994 18 5 1280 1285 2-s2.0-0027986662 10.1111/j.1530-0277.1994. tb00119.x (Pubitemid 24345545)
    • (1994) Alcoholism: Clinical and Experimental Research , vol.18 , Issue.5 , pp. 1280-1285
    • Nanji, A.A.1    Zhao, S.2    Sadrzadeh, S.M.H.3    Dannenberg, A.J.4    Tahan, S.R.5    Waxman, D.J.6
  • 50
    • 77957946415 scopus 로고    scopus 로고
    • Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: Role of signal transducer and activator of transcription 3
    • 2-s2.0-77957946415 10.1002/hep.23837
    • Ki S. H., Park O., Zheng M., Morales-Ibanez O., Kolls J. K., Bataller R., Gao B., Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: role of signal transducer and activator of transcription 3. Hepatology 2010 52 4 1291 1300 2-s2.0-77957946415 10.1002/hep.23837
    • (2010) Hepatology , vol.52 , Issue.4 , pp. 1291-1300
    • Ki, S.H.1    Park, O.2    Zheng, M.3    Morales-Ibanez, O.4    Kolls, J.K.5    Bataller, R.6    Gao, B.7
  • 51
    • 66649122286 scopus 로고    scopus 로고
    • Interleukin-1 β and the autoinflammatory diseases
    • 2-s2.0-66649122286 10.1056/NEJMe0811014
    • Dinarello C. A., Interleukin-1 β and the autoinflammatory diseases. The New England Journal of Medicine 2009 360 23 2467 2470 2-s2.0-66649122286 10.1056/NEJMe0811014
    • (2009) The New England Journal of Medicine , vol.360 , Issue.23 , pp. 2467-2470
    • Dinarello, C.A.1
  • 52
    • 84867176929 scopus 로고    scopus 로고
    • IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice
    • Petrasek J., Bala S., Csak T., IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice. The Journal of Clinical Investigation 2012 122 3476 3489
    • (2012) The Journal of Clinical Investigation , vol.122 , pp. 3476-3489
    • Petrasek, J.1    Bala, S.2    Csak, T.3
  • 55
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • DOI 10.1016/j.cell.2006.02.015, PII S0092867406001905
    • Akira S., Uematsu S., Takeuchi O., Pathogen recognition and innate immunity. Cell 2006 124 4 783 801 2-s2.0-32944464648 10.1016/j.cell.2006.02.015 (Pubitemid 43261452)
    • (2006) Cell , vol.124 , Issue.4 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 56
    • 33646539166 scopus 로고    scopus 로고
    • Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liver
    • DOI 10.1002/hep.21138
    • Gustot T., Lemmers A., Moreno C., Nagy N., Quertinmont E., Nicaise C., Franchimont D., Louis H., Devière J., Le Moine O., Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liver. Hepatology 2006 43 5 989 1000 2-s2.0-33646539166 10.1002/hep.21138 (Pubitemid 43724624)
    • (2006) Hepatology , vol.43 , Issue.5 , pp. 989-1000
    • Gustot, T.1    Lemmers, A.2    Moreno, C.3    Nagy, N.4    Quertinmont, E.5    Nicaise, C.6    Franchimont, D.7    Louis, H.8    Deviere, J.9    Le Moine, O.10
  • 57
    • 54449092214 scopus 로고    scopus 로고
    • The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88
    • 2-s2.0-54449092214 10.1002/hep.22470
    • Hritz I., Mandrekar P., Velayudham A., Catalano D., Dolganiuc A., Kodys K., Kurt-Jones E., Szabo G., The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88. Hepatology 2008 48 4 1224 1231 2-s2.0-54449092214 10.1002/hep.22470
    • (2008) Hepatology , vol.48 , Issue.4 , pp. 1224-1231
    • Hritz, I.1    Mandrekar, P.2    Velayudham, A.3    Catalano, D.4    Dolganiuc, A.5    Kodys, K.6    Kurt-Jones, E.7    Szabo, G.8
  • 58
    • 47149105036 scopus 로고    scopus 로고
    • Toll-like receptors and adaptor molecules in liver disease: Update
    • DOI 10.1002/hep.22306
    • Seki E., Brenner D. A., Toll-like receptors and adaptor molecules in liver disease: update. Hepatology 2008 48 1 322 335 2-s2.0-47149105036 10.1002/hep.22306 (Pubitemid 351975556)
    • (2008) Hepatology , vol.48 , Issue.1 , pp. 322-335
    • Seki, E.1    Brenner, D.A.2
  • 59
    • 18744399291 scopus 로고    scopus 로고
    • Toll-like receptor signaling inhibits hepatitis B virus replication in vivo
    • DOI 10.1128/JVI.79.11.7269-7272.2005
    • Isogawa M., Robek M. D., Furuichi Y., Chisari F. V., Toll-like receptor signaling inhibits hepatitis B virus replication in vivo. Journal of Virology 2005 79 11 7269 7272 2-s2.0-18744399291 10.1128/JVI.79.11.7269-7272.2005 (Pubitemid 40677357)
    • (2005) Journal of Virology , vol.79 , Issue.11 , pp. 7269-7272
    • Isogawa, M.1    Robek, M.D.2    Furuichi, Y.3    Chisari, F.V.4
  • 60
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila toll protein signals activation of adaptive immunity
    • DOI 10.1038/41131
    • Medzhitov R., Preston-Hurlburt P., Janeway C. A. Jr., A human homologue of the Drosophila toll protein signals activation of adaptive immunity. Nature 1997 388 6640 394 397 2-s2.0-0030831210 10.1038/41131 (Pubitemid 27334820)
    • (1997) Nature , vol.388 , Issue.6640 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 61
    • 0043176281 scopus 로고    scopus 로고
    • Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
    • DOI 10.1126/science.1087262
    • Yamamoto M., Sato S., Hemmi H., Hoshino K., Kaisho T., Sanjo H., Takeuchi O., Sugiyama M., Okabe M., Takeda K., Akira S., Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 2003 301 5633 640 643 2-s2.0-0043176281 10.1126/science.1087262 (Pubitemid 36927946)
    • (2003) Science , vol.301 , Issue.5633 , pp. 640-643
    • Yamamoto, M.1    Sato, S.2    Hemmi, H.3    Hoshino, K.4    Kaisho, T.5    Sanjo, H.6    Takeuchi, O.7    Sugiyama, M.8    Okabe, M.9    Takeda, K.10    Akira, S.11
  • 63
    • 79955471005 scopus 로고    scopus 로고
    • The unfolding web of innate immune dysregulation in alcoholic liver injury
    • 2-s2.0-79955471005 10.1111/j.1530-0277.2010.01398.x
    • Szabo G., Mandrekar P., Petrasek J., Catalano D., The unfolding web of innate immune dysregulation in alcoholic liver injury. Alcoholism 2011 35 5 782 786 2-s2.0-79955471005 10.1111/j.1530-0277.2010.01398.x
    • (2011) Alcoholism , vol.35 , Issue.5 , pp. 782-786
    • Szabo, G.1    Mandrekar, P.2    Petrasek, J.3    Catalano, D.4
  • 65
    • 0038185316 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells
    • DOI 10.1053/jhep.2003.50182
    • Paik Y.-H., Schwabe R. F., Bataller R., Russo M. P., Jobin C., Brenner D. A., Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells. Hepatology 2003 37 5 1043 1055 2-s2.0-0038185316 10.1053/jhep.2003.50182 (Pubitemid 36538681)
    • (2003) Hepatology , vol.37 , Issue.5 , pp. 1043-1055
    • Paik, Y.-H.1    Schwabe, R.F.2    Bataller, R.3    Russo, M.P.4    Jobin, C.5    Brenner, D.A.6
  • 66
    • 0141625009 scopus 로고    scopus 로고
    • Recent insights into the role of the innate immune system in the development of alcoholic liver disease
    • Nagy L. E., Recent insights into the role of the innate immune system in the development of alcoholic liver disease. Experimental Biology and Medicine 2003 228 8 882 890 2-s2.0-0141625009 (Pubitemid 37163241)
    • (2003) Experimental Biology and Medicine , vol.228 , Issue.8 , pp. 882-890
    • Nagy, L.E.1
  • 68
    • 0026078067 scopus 로고
    • Plasma endotoxin concentrations in patients with alcoholic and non-alcoholic liver disease: Reevaluation with an improved chromogenic assay
    • 2-s2.0-0026078067
    • Fukui H., Brauner B., Bode J. C., Bode C., Plasma endotoxin concentrations in patients with alcoholic and non-alcoholic liver disease: reevaluation with an improved chromogenic assay. Journal of Hepatology 1991 12 2 162 169 2-s2.0-0026078067
    • (1991) Journal of Hepatology , vol.12 , Issue.2 , pp. 162-169
    • Fukui, H.1    Brauner, B.2    Bode, J.C.3    Bode, C.4
  • 69
    • 33646539166 scopus 로고    scopus 로고
    • Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liver
    • DOI 10.1002/hep.21138
    • Gustot T., Lemmers A., Moreno C., Nagy N., Quertinmont E., Nicaise C., Franchimont D., Louis H., Devière J., Le Moine O., Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liver. Hepatology 2006 43 5 989 1000 2-s2.0-33646539166 10.1002/hep.21138 (Pubitemid 43724624)
    • (2006) Hepatology , vol.43 , Issue.5 , pp. 989-1000
    • Gustot, T.1    Lemmers, A.2    Moreno, C.3    Nagy, N.4    Quertinmont, E.5    Nicaise, C.6    Franchimont, D.7    Louis, H.8    Deviere, J.9    Le Moine, O.10
  • 70
    • 33644781712 scopus 로고    scopus 로고
    • Moderate alcohol intake in humans attenuates monocyte inflammatory responses: Inhibition of nuclear regulatory factor kappa B and induction of interleukin 10
    • DOI 10.1111/j.1530-0277.2006.00012.x
    • Mandrekar P., Catalano D., White B., Szabo G., Moderate alcohol intake in humans attenuates monocyte inflammatory responses: inhibition of nuclear regulatory factor kappa B and induction of interleukin 10. Alcoholism 2006 30 1 135 139 2-s2.0-33644781712 10.1111/j.1530-0277.2006.00012.x (Pubitemid 43341406)
    • (2006) Alcoholism: Clinical and Experimental Research , vol.30 , Issue.1 , pp. 135-139
    • Mandrekar, P.1    Catalano, D.2    White, B.3    Szabo, G.4
  • 71
    • 84872366958 scopus 로고    scopus 로고
    • Activation of toll-like receptor 3 attenuates alcoholic liver injury by stimulating Kupffer cells and stellate cells to produce interleukin-10 in mice
    • Byun J. S., Suh Y. G., Yi H. S., Activation of toll-like receptor 3 attenuates alcoholic liver injury by stimulating Kupffer cells and stellate cells to produce interleukin-10 in mice. Journal of Hepatology 2013 58 342 349
    • (2013) Journal of Hepatology , vol.58 , pp. 342-349
    • Byun, J.S.1    Suh, Y.G.2    Yi, H.S.3
  • 72
    • 47049129929 scopus 로고    scopus 로고
    • Epstein-Barr virus-encoded small RNA induces IL-10 through RIG-I-mediated IRF-3 signaling
    • DOI 10.1038/onc.2008.75, PII ONC200875
    • Samanta M., Iwakiri D., Takada K., Epstein-Barr virus-encoded small RNA induces IL-10 through RIG-I-mediated IRF-3 signaling. Oncogene 2008 27 30 4150 4160 2-s2.0-47049129929 10.1038/onc.2008.75 (Pubitemid 351969916)
    • (2008) Oncogene , vol.27 , Issue.30 , pp. 4150-4160
    • Samanta, M.1    Iwakiri, D.2    Takada, K.3
  • 73
    • 33744539798 scopus 로고    scopus 로고
    • Toll-Like Receptors and RNA Helicases: Two Parallel Ways to Trigger Antiviral Responses
    • DOI 10.1016/j.molcel.2006.05.012, PII S1097276506003273
    • Meylan E., Tschopp J., Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses. Molecular Cell 2006 22 5 561 569 2-s2.0-33744539798 10.1016/j.molcel.2006.05.012 (Pubitemid 43817607)
    • (2006) Molecular Cell , vol.22 , Issue.5 , pp. 561-569
    • Meylan, E.1    Tschopp, J.2
  • 74
    • 51549118941 scopus 로고    scopus 로고
    • TRIF and IRF-3 binding to the TNF promoter results in macrophage TNF dysregulation and steatosis induced by chronic ethanol
    • 2-s2.0-51549118941
    • Zhao X.-J., Dong Q., Bindas J., Piganelli J. D., Magill A., Reiser J., Kolls J. K., TRIF and IRF-3 binding to the TNF promoter results in macrophage TNF dysregulation and steatosis induced by chronic ethanol. Journal of Immunology 2008 181 5 3049 3056 2-s2.0-51549118941
    • (2008) Journal of Immunology , vol.181 , Issue.5 , pp. 3049-3056
    • Zhao, X.-J.1    Dong, Q.2    Bindas, J.3    Piganelli, J.D.4    Magill, A.5    Reiser, J.6    Kolls, J.K.7
  • 75
    • 65249087414 scopus 로고    scopus 로고
    • Hepatic expression of CXC chemokines predicts portal hypertension and survival in patients with alcoholic hepatitis
    • 2-s2.0-65249087414 10.1053/j.gastro.2009.01.056
    • Dominguez M., Miquel R., Colmenero J., Moreno M., García- Pagán J.-C., Bosch J., Arroyo V., Ginès P., Caballería J., Bataller R., Hepatic expression of CXC chemokines predicts portal hypertension and survival in patients with alcoholic hepatitis. Gastroenterology 2009 136 5 1639 1650 2-s2.0-65249087414 10.1053/j.gastro.2009.01.056
    • (2009) Gastroenterology , vol.136 , Issue.5 , pp. 1639-1650
    • Dominguez, M.1    Miquel, R.2    Colmenero, J.3    Moreno, M.4    García-Pagán, J.-C.5    Bosch, J.6    Arroyo, V.7    Ginès, P.8    Caballería, J.9    Bataller, R.10
  • 76
    • 33847039276 scopus 로고    scopus 로고
    • Hepatic Expression of Candidate Genes in Patients With Alcoholic Hepatitis: Correlation With Disease Severity
    • DOI 10.1053/j.gastro.2006.12.036, PII S0016508506026862
    • Colmenero J., Bataller R., Sancho-Bru P., Bellot P., Miquel R., Moreno M., Jares P., Bosch J., Arroyo V., Caballería J., Ginès P., Hepatic expression of candidate genes in patients with alcoholic hepatitis: correlation with disease severity. Gastroenterology 2007 132 2 687 697 2-s2.0-33847039276 10.1053/j.gastro.2006.12.036 (Pubitemid 46274670)
    • (2007) Gastroenterology , vol.132 , Issue.2 , pp. 687-697
    • Colmenero, J.1    Bataller, R.2    Sancho-Bru, P.3    Bellot, P.4    Miquel, R.5    Moreno, M.6    Jares, P.7    Bosch, J.8    Arroyo, V.9    Caballeria, J.10    Gines, P.11
  • 77
    • 0037284514 scopus 로고    scopus 로고
    • Chemokines in the pathogenesis of liver disease: So many players with poorly defined roles
    • DOI 10.1042/CS20020137
    • Simpson K. J., Henderson N. C., Bone-Larson C. L., Lukacs N. W., Hogaboam C. M., Kunkel S. L., Chemokines in the pathogenesis of liver disease: so many players with poorly defined roles. Clinical Science 2003 104 1 47 63 2-s2.0-0037284514 10.1042/CS20020137 (Pubitemid 36249923)
    • (2003) Clinical Science , vol.104 , Issue.1 , pp. 47-63
    • Simpson, K.J.1    Henderson, N.C.2    Bone-Larson, C.L.3    Lukacs, N.W.4    Hogaboam, C.M.5    Kunkel, S.L.6
  • 78
    • 0026547872 scopus 로고
    • Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes
    • 2-s2.0-0026547872
    • Jiang Y., Beller D. I., Frendl G., Graves D. T., Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes. Journal of Immunology 1992 148 8 2423 2428 2-s2.0-0026547872
    • (1992) Journal of Immunology , vol.148 , Issue.8 , pp. 2423-2428
    • Jiang, Y.1    Beller, D.I.2    Frendl, G.3    Graves, D.T.4
  • 79
    • 0032795476 scopus 로고    scopus 로고
    • Serum concentrations and peripheral secretion of the beta chemokines monocyte chemoattractant protein 1 and macrophage inflammatory protein 1 α in alcoholic liver disease
    • Fisher N. C., Neil D. A. H., Williams A., Adams D. H., Serum concentrations and peripheral secretion of the beta chemokines monocyte chemoattractant protein 1 and macrophage inflammatory protein 1 α in alcoholic liver disease. Gut 1999 45 3 416 420 2-s2.0-0032795476 (Pubitemid 29400720)
    • (1999) Gut , vol.45 , Issue.3 , pp. 416-420
    • Fisher, N.C.1    Neil, D.A.H.2    Williams, A.3    Adams, D.H.4
  • 80
    • 0032536531 scopus 로고    scopus 로고
    • Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice
    • DOI 10.1084/jem.187.4.601
    • Lu B., Rutledge B. J., Gu L., Fiorillo J., Lukacs N. W., Kunkel S. L., North R., Gerard C., Rollins B. J., Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. The Journal of Experimental Medicine 1998 187 4 601 608 2-s2.0-0032536531 10.1084/jem.187.4.601 (Pubitemid 28093362)
    • (1998) Journal of Experimental Medicine , vol.187 , Issue.4 , pp. 601-608
    • Lu, B.1    Rutledge, B.J.2    Gu, L.3    Fiorillo, J.4    Lukacs, N.W.5    Kunkel, S.L.6    North, R.7    Gerard, C.8    Rollins, B.J.9
  • 81
    • 82455167937 scopus 로고    scopus 로고
    • An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: Regulation of proinflammatory cytokines and hepatic steatosis in mice
    • 2-s2.0-82455167937 10.1002/hep.24599
    • Mandrekar P., Ambade A., Lim A., Szabo G., Catalano D., An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice. Hepatology 2011 54 6 2185 2197 2-s2.0-82455167937 10.1002/hep.24599
    • (2011) Hepatology , vol.54 , Issue.6 , pp. 2185-2197
    • Mandrekar, P.1    Ambade, A.2    Lim, A.3    Szabo, G.4    Catalano, D.5
  • 82
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • 2-s2.0-77950362382 10.1016/j.cell.2010.01.040
    • Schroder K., Tschopp J., The inflammasomes. Cell 2010 140 6 821 832 2-s2.0-77950362382 10.1016/j.cell.2010.01.040
    • (2010) Cell , vol.140 , Issue.6 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 83
    • 67049158193 scopus 로고    scopus 로고
    • The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1
    • 2-s2.0-67049158193 10.1073/pnas.0812690106
    • Cayrol C., Girard J.-P., The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. Proceedings of the National Academy of Sciences of the United States of America 2009 106 22 9021 9026 2-s2.0-67049158193 10.1073/pnas.0812690106
    • (2009) Proceedings of the National Academy of Sciences of the United States of America , vol.106 , Issue.22 , pp. 9021-9026
    • Cayrol, C.1    Girard, J.-P.2
  • 84
    • 66749174867 scopus 로고    scopus 로고
    • The inflammasomes: Guardians of the body
    • 2-s2.0-66749174867 10.1146/annurev.immunol.021908.132715
    • Martinon F., Mayor A., Tschopp J., The inflammasomes: guardians of the body. Annual Review of Immunology 2009 27 229 265 2-s2.0-66749174867 10.1146/annurev.immunol.021908.132715
    • (2009) Annual Review of Immunology , vol.27 , pp. 229-265
    • Martinon, F.1    Mayor, A.2    Tschopp, J.3
  • 86
    • 77956103055 scopus 로고    scopus 로고
    • Quantitative expression of RIG-like helicase, NOD-like receptor and inflammasome-related mRNAs in humans and mice
    • 2-s2.0-77956103055 10.1093/intimm/dxq058
    • Lech M., Avila-Ferrufino A., Skuginna V., Susanti H. E., Anders H.-J., Quantitative expression of RIG-like helicase, NOD-like receptor and inflammasome-related mRNAs in humans and mice. International Immunology 2010 22 9 717 728 2-s2.0-77956103055 10.1093/intimm/dxq058
    • (2010) International Immunology , vol.22 , Issue.9 , pp. 717-728
    • Lech, M.1    Avila-Ferrufino, A.2    Skuginna, V.3    Susanti, H.E.4    Anders, H.-J.5
  • 87
    • 0011024223 scopus 로고    scopus 로고
    • The glutathione precursor L-2-oxothiazolidine-4-carboxylic acid protects against liver injury due to chronic enteral ethanol exposure in the rat
    • Iimuro Y., Bradford B. U., Yamashina S., Rusyn I., Nakagami M., Enomoto N., Kono H., Frey W., Forman D., Brenner D., Thurman R. G., The glutathione precursor L-2-oxothiazolidine-4-carboxylic acid protects against liver injury due to chronic enteral ethanol exposure in the rat. Hepatology 2000 31 2 391 398 2-s2.0-0011024223 (Pubitemid 30078604)
    • (2000) Hepatology , vol.31 , Issue.2 , pp. 391-398
    • Iimuro, Y.1    Bradford, B.U.2    Yamashina, S.3    Rusyn, I.4    Nakagami, M.5    Enomoto, N.6    Kono, H.7    Frey, W.8    Forman, D.9    Brenner, D.10    Thurman, R.G.11
  • 88
    • 0032904051 scopus 로고    scopus 로고
    • Ethanol-induced apoptosis to stable HepG2 cell lines expressing human cytochrome P-4502E1
    • Wu D., Cederbaum A. I., Ethanol-induced apoptosis to stable HepG2 cell lines expressing human cytochrome P-4502E1. Alcoholism 1999 23 1 67 76 2-s2.0-0032904051 (Pubitemid 29068468)
    • (1999) Alcoholism: Clinical and Experimental Research , vol.23 , Issue.1 , pp. 67-76
    • Wu, D.1    Cederbaum, A.I.2
  • 89
    • 16544368662 scopus 로고    scopus 로고
    • Endotoxin and kupffer cell activation in alcoholic liver disease
    • Wheeler M. D., Endotoxin and kupffer cell activation in alcoholic liver disease. Alcohol Research and Health 2003 27 4 300 306 2-s2.0-16544368662 (Pubitemid 40685569)
    • (2003) Alcohol Research and Health , vol.27 , Issue.4 , pp. 300-306
    • Wheeler, M.D.1
  • 90
    • 39749090649 scopus 로고    scopus 로고
    • Oxidative mechanisms in the pathogenesis of alcoholic liver disease
    • DOI 10.1016/j.mam.2007.09.004, PII S0098299707000830
    • Albano E., Oxidative mechanisms in the pathogenesis of alcoholic liver disease. Molecular Aspects of Medicine 2008 29 1-2 9 16 2-s2.0-39749090649 10.1016/j.mam.2007.09.004 (Pubitemid 351312214)
    • (2008) Molecular Aspects of Medicine , vol.29 , Issue.1-2 , pp. 9-16
    • Albano, E.1
  • 91
    • 59549106331 scopus 로고    scopus 로고
    • Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats
    • 2-s2.0-59549106331 10.1016/j.jhep.2008.10.028
    • Keshavarzian A., Farhadi A., Forsyth C. B., Rangan J., Jakate S., Shaikh M., Banan A., Fields J. Z., Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats. Journal of Hepatology 2009 50 3 538 547 2-s2.0-59549106331 10.1016/j.jhep.2008.10.028
    • (2009) Journal of Hepatology , vol.50 , Issue.3 , pp. 538-547
    • Keshavarzian, A.1    Farhadi, A.2    Forsyth, C.B.3    Rangan, J.4    Jakate, S.5    Shaikh, M.6    Banan, A.7    Fields, J.Z.8
  • 92
    • 0032920540 scopus 로고    scopus 로고
    • Leaky gut in alcoholic cirrhosis: A possible mechanism for alcohol- induced liver damage
    • DOI 10.1111/j.1572-0241.1999.00797.x, PII S0002927098006789
    • Keshavarzian A., Holmes E. W., Patel M., Iber F., Fields J. Z., Pethkar S., Leaky gut in alcoholic cirrhosis: a possible mechanism for alcohol- induced liver damage. American Journal of Gastroenterology 1999 94 1 200 207 2-s2.0-0032920540 10.1111/j.1572-0241.1999.00797.x (Pubitemid 29063469)
    • (1999) American Journal of Gastroenterology , vol.94 , Issue.1 , pp. 200-207
    • Keshavarzian, A.1    Holmes, E.W.2    Patel, M.3    Iber, F.4    Fields, J.Z.5    Pethkar, S.6
  • 93
    • 78651399501 scopus 로고    scopus 로고
    • Up-regulation of microRNA-155 in macrophages contributes to increased Tumor Necrosis Factor α (TNF α) production via increased mRNA half-life in alcoholic liver disease
    • 2-s2.0-78651399501 10.1074/jbc.M110.145870
    • Bala S., Marcos M., Kodys K., Csak T., Catalano D., Mandrekar P., Szabo G., Up-regulation of microRNA-155 in macrophages contributes to increased Tumor Necrosis Factor α (TNF α) production via increased mRNA half-life in alcoholic liver disease. Journal of Biological Chemistry 2011 286 2 1436 1444 2-s2.0-78651399501 10.1074/jbc.M110.145870
    • (2011) Journal of Biological Chemistry , vol.286 , Issue.2 , pp. 1436-1444
    • Bala, S.1    Marcos, M.2    Kodys, K.3    Csak, T.4    Catalano, D.5    Mandrekar, P.6    Szabo, G.7
  • 94
    • 33847743407 scopus 로고    scopus 로고
    • Acetaldehyde dissociates the PTP1B-E-cadherin-β-catenin complex in Caco-2 cell monolayers by a phosphorylation-dependent mechanism
    • DOI 10.1042/BJ20060665
    • Sheth P., Seth A., Atkinson K. J., Gheyi T., Kale G., Giorgianni F., Desiderio D. M., Li C., Naren A., Rao R., Acetaldehyde dissociates the PTP1B-E-cadherin- β -catenin complex in Caco-2 cell monolayers by a phosphorylation-dependent mechanism. The Biochemical Journal 2007 402 2 291 300 2-s2.0-33847743407 10.1042/BJ20060665 (Pubitemid 46383426)
    • (2007) Biochemical Journal , vol.402 , Issue.2 , pp. 291-300
    • Sheth, P.1    Seth, A.2    Atkinson, K.J.3    Gheyi, T.4    Kale, G.5    Giorgianni, F.6    Desiderio, D.M.7    Li, C.8    Naren, A.9    Rao, R.10
  • 95
    • 0034940506 scopus 로고    scopus 로고
    • The effect of long-term ethanol feeding on Brucella melitensis infection of rats
    • Yumuk Z., Ozdemirci S., Faruk Erden B., Dundar V., The effect of long-term ethanol feeding on Brucella melitensis infection of rats. Alcohol and Alcoholism 2001 36 4 314 317 2-s2.0-0034940506 (Pubitemid 32655228)
    • (2001) Alcohol and Alcoholism , vol.36 , Issue.4 , pp. 314-317
    • Yumuk, Z.1    Ozdemirci, S.2    Faruk Erden, B.3    Dundar, V.4
  • 96
    • 14944370045 scopus 로고    scopus 로고
    • Effect of acute alcohol ingestion prior to burn injury on intestinal bacterial growth and barrier function
    • DOI 10.1016/j.burns.2004.09.021
    • Kavanaugh M. J., Clark C., Goto M., Kovacs E. J., Gamelli R. L., Sayeed M. M., Choudhry M. A., Effect of acute alcohol ingestion prior to burn injury on intestinal bacterial growth and barrier function. Burns 2005 31 3 290 296 2-s2.0-14944370045 10.1016/j.burns.2004.09.021 (Pubitemid 40363935)
    • (2005) Burns , vol.31 , Issue.3 , pp. 290-296
    • Kavanaugh, M.J.1    Clark, C.2    Goto, M.3    Kovacs, E.J.4    Gamelli, R.L.5    Sayeed, M.M.6    Choudhry, M.A.7
  • 98
    • 34249809161 scopus 로고    scopus 로고
    • Regulation of macrophage activation in alcoholic liver disease
    • DOI 10.1111/j.1440-1746.2006.04650.x
    • Thakur V., McMullen M. R., Pritchard M. T., Nagy L. E., Regulation of macrophage activation in alcoholic liver disease. Journal of Gastroenterology and Hepatology 2007 22 1 S53 S56 2-s2.0-34249809161 10.1111/j.1440-1746.2006. 04650.x (Pubitemid 46848991)
    • (2007) Journal of Gastroenterology and Hepatology , vol.22 , Issue.SUPPL. 1
    • Thakur, V.1    McMullen, M.R.2    Pritchard, M.T.3    Nagy, L.E.4
  • 99
    • 68949178506 scopus 로고    scopus 로고
    • Endotoxemia and gut barrier dysfunction in alcoholic liver disease
    • 2-s2.0-68949178506 10.1002/hep.23009
    • Rao R., Endotoxemia and gut barrier dysfunction in alcoholic liver disease. Hepatology 2009 50 2 638 644 2-s2.0-68949178506 10.1002/hep.23009
    • (2009) Hepatology , vol.50 , Issue.2 , pp. 638-644
    • Rao, R.1
  • 101
    • 0027997978 scopus 로고
    • The differing effects of acute and chronic alcohol on gastric and intestinal permeability
    • Keshavarzian A., Fields J. Z., Vaeth J., Holmes E. W., The differing effects of acute and chronic alcohol on gastric and intestinal permeability. American Journal of Gastroenterology 1994 89 12 2205 2211 2-s2.0-0027997978 (Pubitemid 24363671)
    • (1994) American Journal of Gastroenterology , vol.89 , Issue.12 , pp. 2205-2211
    • Keshavarzian, A.1    Fields, J.Z.2    Vaeth, J.3    Holmes, E.W.4
  • 104
    • 77950825001 scopus 로고    scopus 로고
    • Alcoholic liver disease and the gut-liver axis
    • 2-s2.0-77950825001 10.3748/wjg.v16.i11.1321
    • Szabo G., Bala S., Alcoholic liver disease and the gut-liver axis. World Journal of Gastroenterology 2010 16 11 1321 1329 2-s2.0-77950825001 10.3748/wjg.v16.i11.1321
    • (2010) World Journal of Gastroenterology , vol.16 , Issue.11 , pp. 1321-1329
    • Szabo, G.1    Bala, S.2
  • 105
    • 0028796860 scopus 로고
    • Antibiotics prevent liver injury in rats following long-term exposure to ethanol
    • 2-s2.0-0028796860 10.1016/0016-5085(95)90027-6
    • Adachi Y., Moore L. E., Bradford B. U., Gao W., Thurman R. G., Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology 1995 108 1 218 224 2-s2.0-0028796860 10.1016/0016-5085(95)90027-6
    • (1995) Gastroenterology , vol.108 , Issue.1 , pp. 218-224
    • Adachi, Y.1    Moore, L.E.2    Bradford, B.U.3    Gao, W.4    Thurman, R.G.5
  • 106
    • 80054872790 scopus 로고    scopus 로고
    • Alcoholic liver disease: Pathogenesis and new therapeutic targets
    • 2-s2.0-80054872790 10.1053/j.gastro.2011.09.002
    • Gao B., Bataller R., Alcoholic liver disease: pathogenesis and new therapeutic targets. Gastroenterology 2011 141 5 1572 1585 2-s2.0-80054872790 10.1053/j.gastro.2011.09.002
    • (2011) Gastroenterology , vol.141 , Issue.5 , pp. 1572-1585
    • Gao, B.1    Bataller, R.2
  • 108
    • 0016600027 scopus 로고
    • Alcoholic liver injury: Experimental models in rats and baboons
    • 2-s2.0-0016600027
    • Lieber C. S., DeCarli L. M., Alcoholic liver injury: experimental models in rats and baboons. Advances in Experimental Medicine and Biology 1975 59 379 393 2-s2.0-0016600027
    • (1975) Advances in Experimental Medicine and Biology , vol.59 , pp. 379-393
    • Lieber, C.S.1    Decarli, L.M.2
  • 109
    • 0021923933 scopus 로고
    • Severe and progressive steatosis and focal necrosis in rat liver induced by continuous intragastric infusion of ethanol and low fat diet
    • DOI 10.1002/hep.1840050212
    • Tsukamoto H., French S. W., Benson N., Severe and progressive steatosis and focal necrosis in rat liver induced by continuous intragastric infusion of ethanol and low fat diet. Hepatology 1985 5 2 224 232 2-s2.0-0021923933 (Pubitemid 15115999)
    • (1985) Hepatology , vol.5 , Issue.2 , pp. 224-232
    • Tsukamoto, H.1    French, S.W.2    Benson, N.3
  • 110
    • 0022510347 scopus 로고
    • Ethanol-induced liver fibrosis in rats fed high fat diet
    • Tsukamoto H., Towner S. J., Ciofalo L. M., French S. W., Ethanol-induced liver fibrosis in rats fed high fat diet. Hepatology 1986 6 5 814 822 2-s2.0-0022510347 (Pubitemid 16006732)
    • (1986) Hepatology , vol.6 , Issue.5 , pp. 814-822
    • Tsukamoto, H.1    Towner, S.J.2    Ciofalo, L.M.3    French, S.W.4
  • 111
    • 0035138847 scopus 로고    scopus 로고
    • Intragastric ethanol infusion model for cellular and molecular studies of alcoholic liver disease
    • DOI 10.1159/000054009
    • French S. W., Intragastric ethanol infusion model for cellular and molecular studies of alcoholic liver disease. Journal of Biomedical Science 2001 8 1 20 27 2-s2.0-0035138847 10.1159/000054009 (Pubitemid 32098482)
    • (2001) Journal of Biomedical Science , vol.8 , Issue.1 , pp. 20-27
    • French, S.W.1
  • 112
    • 0028220726 scopus 로고
    • Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver (disease)
    • Nanji A. A., Khettry U., Sadrzadeh S. M. H., Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver (disease). Proceedings of the Society for Experimental Biology and Medicine 1994 205 3 243 247 2-s2.0-0028220726 (Pubitemid 24108319)
    • (1994) Proceedings of the Society for Experimental Biology and Medicine , vol.205 , Issue.3 , pp. 243-247
    • Nanji, A.A.1    Khettry, U.2    Sadrzadeh, S.M.H.3
  • 113
    • 69249225655 scopus 로고    scopus 로고
    • Recent developments in the treatment of alcoholic chronic pancreatitis
    • 2-s2.0-69249225655
    • Tsujimoto T., Kawaratani H., Yoshiji H., Uemura M., Fukui H., Recent developments in the treatment of alcoholic chronic pancreatitis. Current Drug Abuse Reviews 2008 1 2 197 202 2-s2.0-69249225655
    • (2008) Current Drug Abuse Reviews , vol.1 , Issue.2 , pp. 197-202
    • Tsujimoto, T.1    Kawaratani, H.2    Yoshiji, H.3    Uemura, M.4    Fukui, H.5


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