-
1
-
-
0026035519
-
Role of human cytochrome P450IIE1 in the oxidation of many low molecular weight cancer suspects
-
Guengerich FP, Kim DH, Iwasaki M: Role of human cytochrome P450IIE1 in the oxidation of many low molecular weight cancer suspects. Chem Res Toxicol 4:168-179, 1991
-
(1991)
Chem Res Toxicol
, vol.4
, pp. 168-179
-
-
Guengerich, F.P.1
Kim, D.H.2
Iwasaki, M.3
-
2
-
-
0026567713
-
Oxidative and reductive metabolism by cytochrome P4502E1
-
Koop DR: Oxidative and reductive metabolism by cytochrome P4502E1. FASEB J 6:724-730, 1992
-
(1992)
FASEB J
, vol.6
, pp. 724-730
-
-
Koop, D.R.1
-
3
-
-
0025167020
-
Cytochrome P450IIE1: Roles in nitrosamine metabolism and mechanisms of regulation
-
Yang CS, Yoo JSH, Ishizaki H, Hong J: Cytochrome P450IIE1: Roles in nitrosamine metabolism and mechanisms of regulation. Drug Metab Rev 22:147-159, 1990
-
(1990)
Drug Metab Rev
, vol.22
, pp. 147-159
-
-
Yang, C.S.1
Yoo, J.S.H.2
Ishizaki, H.3
Hong, J.4
-
4
-
-
0021138883
-
On the stoichiometry of the oxidase and monooxygenase reactions catalyzed by liver microsomal cytochrome P450
-
Gorsky LD, Koop DR, Coon MJ: On the stoichiometry of the oxidase and monooxygenase reactions catalyzed by liver microsomal cytochrome P450. J Biol Chem 259:6812-6817, 1984
-
(1984)
J Biol Chem
, vol.259
, pp. 6812-6817
-
-
Gorsky, L.D.1
Koop, D.R.2
Coon, M.J.3
-
5
-
-
0024546914
-
Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P450 (P-450IIE1)
-
Ekstrom G, Ingelman-Sundberg M: Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P450 (P-450IIE1). Biochem Pharmacol 38:1313-1318, 1989
-
(1989)
Biochem Pharmacol
, vol.38
, pp. 1313-1318
-
-
Ekstrom, G.1
Ingelman-Sundberg, M.2
-
6
-
-
0021810423
-
Lipid peroxidation in ethanol poisoning: A critical reconsideration
-
Dianzani MU: Lipid peroxidation in ethanol poisoning: A critical reconsideration. Alcohol Alcohol 20:161-173, 1985
-
(1985)
Alcohol Alcohol
, vol.20
, pp. 161-173
-
-
Dianzani, M.U.1
-
7
-
-
0024847570
-
Oxygen radical generation by microsomes: Role of iron and implications for alcohol metabolism and toxicity
-
Cederbaum AI: Oxygen radical generation by microsomes: Role of iron and implications for alcohol metabolism and toxicity. Free Radic Biol Med 7:559-567, 1989
-
(1989)
Free Radic Biol Med
, vol.7
, pp. 559-567
-
-
Cederbaum, A.I.1
-
8
-
-
0026554148
-
Implications of free radical mechanisms in ethanol-induced cellular injury
-
Nordmann R, Ribiere C, Rouach H: Implications of free radical mechanisms in ethanol-induced cellular injury. Free Radic Biol Med 12:219-240, 1992
-
(1992)
Free Radic Biol Med
, vol.12
, pp. 219-240
-
-
Nordmann, R.1
Ribiere, C.2
Rouach, H.3
-
10
-
-
0027986662
-
Markedly enhanced cytochrome P4502E1 induction and lipid peroxidation is associated with severe liver injury in fish oil-ethanol-fed rats
-
Nanji AA, Zhao S, Sadrzadeh SMH, Dannenberg AJ, Tahan SR, Waxman DJ: Markedly enhanced cytochrome P4502E1 induction and lipid peroxidation is associated with severe liver injury in fish oil-ethanol-fed rats. Alcohol Clin Exp Res 18:1280-1285, 1994
-
(1994)
Alcohol Clin Exp Res
, vol.18
, pp. 1280-1285
-
-
Nanji, A.A.1
Zhao, S.2
Sadrzadeh, S.M.H.3
Dannenberg, A.J.4
Tahan, S.R.5
Waxman, D.J.6
-
11
-
-
0028051780
-
Fish oil, alcohol, and liver pathology: Role of cytochrome P4502E1
-
Morimoto M, Zern MA, Hagbjork AL, Ingelman-Sundberg M, French SW: Fish oil, alcohol, and liver pathology: Role of cytochrome P4502E1. Proc Soc Exp Biol Med 207:197-205, 1994
-
(1994)
Proc Soc Exp Biol Med
, vol.207
, pp. 197-205
-
-
Morimoto, M.1
Zern, M.A.2
Hagbjork, A.L.3
Ingelman-Sundberg, M.4
French, S.W.5
-
12
-
-
0027185531
-
Stable expression of human cytochrome P4502E1 in HepG2 cells: Characterization of catalytic activities and production of reactive oxygen intermediates
-
Dai Y, Rashba-Step J, Cederbaum AI: Stable expression of human cytochrome P4502E1 in HepG2 cells: Characterization of catalytic activities and production of reactive oxygen intermediates. Biochemistry 32:6928-6937, 1993
-
(1993)
Biochemistry
, vol.32
, pp. 6928-6937
-
-
Dai, Y.1
Rashba-Step, J.2
Cederbaum, A.I.3
-
13
-
-
0029816454
-
Ethanol cytotoxicity to a transfected HepG2 cell line expressing human cytochrome P4502E1
-
Wu D, Cederbaum AI: Ethanol cytotoxicity to a transfected HepG2 cell line expressing human cytochrome P4502E1. J Biol Chem 271:23914-23919, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 23914-23919
-
-
Wu, D.1
Cederbaum, A.I.2
-
14
-
-
0028815621
-
Dithiocarbamates induce apoptosis in thymocytes by raising the intracellular level of redox active copper
-
Nobel CL, Kimland M, Lind B, Orrenius S, Slater AF: Dithiocarbamates induce apoptosis in thymocytes by raising the intracellular level of redox active copper. J Biol Chem 270:26202-26208, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 26202-26208
-
-
Nobel, C.L.1
Kimland, M.2
Lind, B.3
Orrenius, S.4
Slater, A.F.5
-
15
-
-
0028040019
-
Bcl-2 and the regulation of programmed cell death
-
Reed JC: Bcl-2 and the regulation of programmed cell death. J Cell Biol 124:1-6, 1994
-
(1994)
J Cell Biol
, vol.124
, pp. 1-6
-
-
Reed, J.C.1
-
16
-
-
0027485461
-
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
-
Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer SJ: Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75:241-251, 1993
-
(1993)
Cell
, vol.75
, pp. 241-251
-
-
Hockenbery, D.M.1
Oltvai, Z.N.2
Yin, X.M.3
Milliman, C.L.4
Korsmeyer, S.J.5
-
17
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr JFR, Wyllie AH, Currie AR: Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257, 1972
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.R.1
Wyllie, A.H.2
Currie, A.R.3
-
18
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
Thompson C: Apoptosis in the pathogenesis and treatment of disease. Science 267:1456-1462, 1995
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.1
-
19
-
-
0029125701
-
Protease activation during apoptosis: Death by a thousand cuts
-
Martin S, Green D: Protease activation during apoptosis: Death by a thousand cuts. Cell 82:349-352, 1995
-
(1995)
Cell
, vol.82
, pp. 349-352
-
-
Martin, S.1
Green, D.2
-
20
-
-
0028105796
-
Developmental regulation of the bcl-2 protein and susceptibility to cell death in lymphocytes
-
Merino R, Ding L, Veis DJ, Korsmeyer SJ, Nunez G: Developmental regulation of the bcl-2 protein and susceptibility to cell death in lymphocytes. EMBO J 13:683-691, 1994
-
(1994)
EMBO J
, vol.13
, pp. 683-691
-
-
Merino, R.1
Ding, L.2
Veis, D.J.3
Korsmeyer, S.J.4
Nunez, G.5
-
21
-
-
0028364494
-
c-MYC and bcl-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycle
-
Ryan JJ, Prochownik E, Gottlieb CA, Apel IJ, Merino R, Nunez G, Clarke MF: c-MYC and bcl-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycle. Proc Natl Acad Sci USA 91:5878-5882, 1994
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 5878-5882
-
-
Ryan, J.J.1
Prochownik, E.2
Gottlieb, C.A.3
Apel, I.J.4
Merino, R.5
Nunez, G.6
Clarke, M.F.7
-
22
-
-
8944230656
-
Fas-induced activation of the cell death-related protease CPP32 is inhibited by bcl-2 and by ICE family protease inhibitors
-
Armstrong RC, Aja T, Xiang J, Gaur S, Krebs JF, Hoang K, Bai X, Korsmeyer SJ, Karanewsky DS, Fritz LC, Tomaselli KJ: Fas-induced activation of the cell death-related protease CPP32 is inhibited by bcl-2 and by ICE family protease inhibitors. J Biol Chem 271:16850-16855, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 16850-16855
-
-
Armstrong, R.C.1
Aja, T.2
Xiang, J.3
Gaur, S.4
Krebs, J.F.5
Hoang, K.6
Bai, X.7
Korsmeyer, S.J.8
Karanewsky, D.S.9
Fritz, L.C.10
Tomaselli, K.J.11
-
23
-
-
0025204548
-
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
-
Hockenbery D, Nunets G, Milliman C, Schreiber RD, Korsmeyer SJ: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334-336, 1990
-
(1990)
Nature
, vol.348
, pp. 334-336
-
-
Hockenbery, D.1
Nunets, G.2
Milliman, C.3
Schreiber, R.D.4
Korsmeyer, S.J.5
-
25
-
-
0031958219
-
Cytotoxicity and apoptosis produced by cytochrome P4502E1 in HepG2 cells
-
Chen Q, Cederbaum AI: Cytotoxicity and apoptosis produced by cytochrome P4502E1 in HepG2 cells. Mol Pharmacol 53:638-648, 1998
-
(1998)
Mol Pharmacol
, vol.53
, pp. 638-648
-
-
Chen, Q.1
Cederbaum, A.I.2
-
26
-
-
0002947302
-
Lipofectamine reagent: A new higher efficiency polycationic liposome transfection reagent
-
Hawley-Nelson P, Ciccarone V, Gebeyehu G, Jessee J, Felgner PL: Lipofectamine reagent: A new higher efficiency polycationic liposome transfection reagent. Focus-Mol Biol Life Tech 15:73-79, 1993
-
(1993)
Focus-mol Biol Life Tech
, vol.15
, pp. 73-79
-
-
Hawley-Nelson, P.1
Ciccarone, V.2
Gebeyehu, G.3
Jessee, J.4
Felgner, P.L.5
-
27
-
-
0022852729
-
In vitro inhibition of microsomal oxidation of ethanol by pyrazole and 4-methylpyrazole
-
Feierman DE, Cederbaum AI: In vitro inhibition of microsomal oxidation of ethanol by pyrazole and 4-methylpyrazole. Biochem J 239: 671-677, 1986
-
(1986)
Biochem J
, vol.239
, pp. 671-677
-
-
Feierman, D.E.1
Cederbaum, A.I.2
-
28
-
-
0030965155
-
Cytotoxicity and apoptosis produced by arachidonic acid in HepG2 cells over-expressing human cytochrome P4502E1
-
Chen Q, Galleano M, Cederbaum AI: Cytotoxicity and apoptosis produced by arachidonic acid in HepG2 cells over-expressing human cytochrome P4502E1. J Biol Chem 272:14532-14541, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 14532-14541
-
-
Chen, Q.1
Galleano, M.2
Cederbaum, A.I.3
-
29
-
-
0031149527
-
Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1
-
Yang MX, Cederbaum AI: Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1. Arch Biochem Biophys 341:25-33, 1997
-
(1997)
Arch Biochem Biophys
, vol.341
, pp. 25-33
-
-
Yang, M.X.1
Cederbaum, A.I.2
-
30
-
-
0027174736
-
Role of superoxide and trace transition metals in the production of alpha-hydroxyethyl radical from microsomes from alcohol dehydrogenase-deficient deermice
-
Knecht KT, Thurman RG, Mason RP: Role of superoxide and trace transition metals in the production of alpha-hydroxyethyl radical from microsomes from alcohol dehydrogenase-deficient deermice. Arch Biochem Biophys 303:339-348, 1993
-
(1993)
Arch Biochem Biophys
, vol.303
, pp. 339-348
-
-
Knecht, K.T.1
Thurman, R.G.2
Mason, R.P.3
-
31
-
-
0031543495
-
Mechanisms for metabolism of ethanol to 1-hydroxyethyl radicals in rat liver microsomes
-
Reinke LA, Moore DR, McCay PB: Mechanisms for metabolism of ethanol to 1-hydroxyethyl radicals in rat liver microsomes. Arch Biochem Biophys 348:9-14, 1997
-
(1997)
Arch Biochem Biophys
, vol.348
, pp. 9-14
-
-
Reinke, L.A.1
Moore, D.R.2
McCay, P.B.3
-
32
-
-
0025809918
-
Role of ethanol-inducible cytochrome P450 in catalyzing free radical activation of aliphatic alcohols
-
Albano E, Tomasi A, Persson JO, Terelius Y, Goria-Gatti L, Ingelman-Sundberg M, Dianzani MU: Role of ethanol-inducible cytochrome P450 in catalyzing free radical activation of aliphatic alcohols. Biochem Pharmacol 41:1895-1902, 1991
-
(1991)
Biochem Pharmacol
, vol.41
, pp. 1895-1902
-
-
Albano, E.1
Tomasi, A.2
Persson, J.O.3
Terelius, Y.4
Goria-Gatti, L.5
Ingelman-Sundberg, M.6
Dianzani, M.U.7
-
33
-
-
0242634526
-
Reactive free radical generation in vivo in heart and liver of ethanol-fed rats: Correlation with radical formation in vitro
-
Reinke LA, Lau EK, DuBose CM, McCay PB: Reactive free radical generation in vivo in heart and liver of ethanol-fed rats: Correlation with radical formation in vitro. Proc Natl Acad Sci USA 87:5499-5503, 1987
-
(1987)
Proc Natl Acad Sci USA
, vol.87
, pp. 5499-5503
-
-
Reinke, L.A.1
Lau, E.K.2
DuBose, C.M.3
McCay, P.B.4
-
34
-
-
0023932025
-
Subcellular changes and apoptosis induced by ethanol in rat liver
-
Benedetti A, Brunelli E, Risicato R, Cilluffo T, Jezequel AM, Orlandi F: Subcellular changes and apoptosis induced by ethanol in rat liver. J Hepatol 6:137-143, 1988
-
(1988)
J Hepatol
, vol.6
, pp. 137-143
-
-
Benedetti, A.1
Brunelli, E.2
Risicato, R.3
Cilluffo, T.4
Jezequel, A.M.5
Orlandi, F.6
-
35
-
-
0027363543
-
Apoptotic bodies in a murine model of alcoholic liver disease
-
Goldin RD, Hunt NC, Clark J, Wickramasinghe SN: Apoptotic bodies in a murine model of alcoholic liver disease. J Pathol 171:73-76, 1993
-
(1993)
J Pathol
, vol.171
, pp. 73-76
-
-
Goldin, R.D.1
Hunt, N.C.2
Clark, J.3
Wickramasinghe, S.N.4
-
36
-
-
0029129182
-
Apoptosis and bcl-2 protein expression in experimental alcoholic liver disease in the rat
-
Yacoub LK, Fogt F, Griniuviene B, Nanji AA: Apoptosis and bcl-2 protein expression in experimental alcoholic liver disease in the rat. Alcohol Clin Exp Res 19:854-859, 1995
-
(1995)
Alcohol Clin Exp Res
, vol.19
, pp. 854-859
-
-
Yacoub, L.K.1
Fogt, F.2
Griniuviene, B.3
Nanji, A.A.4
-
37
-
-
0030479473
-
Ethanol-induced apoptosis and oxidative stress in hepatocytes
-
Higuchi H, Kurose I, Kato S, Miura S, Ishii H: Ethanol-induced apoptosis and oxidative stress in hepatocytes. Alcohol Clin Exp Res 20S:340A-346A, 1996
-
(1996)
Alcohol Clin Exp Res
, vol.20 S
-
-
Higuchi, H.1
Kurose, I.2
Kato, S.3
Miura, S.4
Ishii, H.5
-
38
-
-
12644291219
-
Oxidative stress mediated apoptosis of hepatocytes exposed to acute ethanol intoxication
-
Kurose I, Higuchi H, Miura S, Saito H, Watanabe N, Hokari R, Hirokawa M, Takaishi M, Zeki S, Nakamura T, Ebinuma H, Kato S, Ishii H: Oxidative stress mediated apoptosis of hepatocytes exposed to acute ethanol intoxication. Hepatology 25:368-378, 1997
-
(1997)
Hepatology
, vol.25
, pp. 368-378
-
-
Kurose, I.1
Higuchi, H.2
Miura, S.3
Saito, H.4
Watanabe, N.5
Hokari, R.6
Hirokawa, M.7
Takaishi, M.8
Zeki, S.9
Nakamura, T.10
Ebinuma, H.11
Kato, S.12
Ishii, H.13
-
39
-
-
0029978182
-
Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis
-
Enari M, Talanian RV, Wong WW, Nagata S: Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 380:723-726, 1996
-
(1996)
Nature
, vol.380
, pp. 723-726
-
-
Enari, M.1
Talanian, R.V.2
Wong, W.W.3
Nagata, S.4
-
40
-
-
0030973417
-
Multiple species of CPP32 and Mch 2 are the major active caspases present in apoptotic cells
-
Faleiro L, Kobayashi R, Fearnhead H, Lazebnik Y: Multiple species of CPP32 and Mch 2 are the major active caspases present in apoptotic cells. EMBO J 16:2271-2281, 1997
-
(1997)
EMBO J
, vol.16
, pp. 2271-2281
-
-
Faleiro, L.1
Kobayashi, R.2
Fearnhead, H.3
Lazebnik, Y.4
-
41
-
-
0029862706
-
Mitochondrial control of nuclear apoptosis
-
Zamzami N, Susin AS, Merchetti P, Hirsch T, Gomez-Monterrey I, Castedo M, Kroemer G: Mitochondrial control of nuclear apoptosis. J Exp Med 183:1533-1544, 1996
-
(1996)
J Exp Med
, vol.183
, pp. 1533-1544
-
-
Zamzami, N.1
Susin, A.S.2
Merchetti, P.3
Hirsch, T.4
Gomez-Monterrey, I.5
Castedo, M.6
Kroemer, G.7
-
42
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts requirement for dATP and cytochrome c
-
Liu X, Kim CN, Yang J, Jemmerson R, Wang X: Induction of apoptotic program in cell-free extracts requirement for dATP and cytochrome c. Cell 86:147-157, 1996
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
43
-
-
0031036872
-
Prevention of apoptosis by bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu X, Bhalla K, Kim CN, Ibrado AM, Cai J, Peng TL, Jones DP, Wang X: Prevention of apoptosis by bcl-2: Release of cytochrome c from mitochondria blocked. Science 275:1129-1132, 1997
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
Kim, C.N.4
Ibrado, A.M.5
Cai, J.6
Peng, T.L.7
Jones, D.P.8
Wang, X.9
-
44
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for bcl-2 regulation of apoptosis
-
Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD: The release of cytochrome c from mitochondria: A primary site for bcl-2 regulation of apoptosis. Science 275:1132-1136, 1997
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
|