Recent advances in alcoholic liver disease. IV. Dysregulated cytokine metabolism in alcoholic liver disease

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 287, Issue 3 50-3, 2004, Pages

  McClain, Craig J ^a   Song, Zhenyuan ^a   Barve, Shirish S ^a   Hill, Daniell B ^a   Deaciuc, Ion ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Apoptosis; Cytokines; Necrosis; Oxidative stress; Tumor necrosis factor

Indexed keywords

CYTOKINE; INTERLEUKIN 18; INTERLEUKIN 6; INTERLEUKIN 8; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ACUTE PHASE RESPONSE; ALCOHOL LIVER CIRRHOSIS; ALCOHOL LIVER DISEASE; CAUSE OF DEATH; CONTROLLED STUDY; HUMAN; LIVER FIBROSIS; LIVER FUNCTION; LIVER INJURY; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW;

ANIMALS; CYTOKINES; HUMANS; LIVER; LIVER CIRRHOSIS; LIVER DISEASES, ALCOHOLIC; LIVER REGENERATION; TRANSFORMING GROWTH FACTOR BETA;

EID: 4143065802     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00171.2004     Document Type: Review

References (30)

1. Akerman PA, Cote PM, Yang SQ, McClain CJ, Nelson S, Bagby G, and Diehl AM. Long-term ethanol consumption alters the hepatic response to the regenerative effects of tumor necrosis factor-α. Hepatology 17: 1066-1073, 1993.
2. Arteel G, Marsano L, Mendez C, Bentley F, and McClain CJ. Advances in alcoholic liver disease. Best Pract Res Clin Gastroenterol 17: 625-647, 2003.
3. Cabre E, Rodriguez-Iglesias P, Caballeria J, Quer JC, Sanchez-Lombrana JL, Pares A, Papo M, Planas R, Gassull MA, and the Spanish Group for the Study of Alcoholic Hepatitis. Short- and long-term outcome of severe alcohol-induced hepatitis treated with steroids or enteral nutrition: a multicenter randomized trial. Hepatology 32: 36-42, 2000.
4. Canbay A, Feldstein AE, Higuchi H, Werneburg N, Grambihler A, Bronk SF, and Gores GJ. Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression. Hepatology 38: 1188-1198, 2003.
5. Chen G and Goeddel DV. TNF-R1 signaling: a beautiful pathway. Science 296: 1634-1635, 2002.
6. Colell A, Garcia-Ruiz C, Miranda M, Ardite E, Mari M, Morales A, Corrales F, Kaplowitz N, and Fernandez-Checa J. Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor. Gastroenterology 115: 1541-1551, 1998.
7. Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 103: 239-252, 2000.
8. Fausto N. Liver regeneration. J Hepatol 32, Suppl 1: 19-31, 2000.
9. Grove J, Daly AK, Bassendine MF, and Day CP. Association of a tumor necrosis factor promoter polymorphism with susceptibility to alcoholic steatohepatitis. Hepatology 26: 143-146, 1997.
10. Hill D, Shedlofsky S, McClain CJ, Diehl AM, and Tsukamoto H. Cytokines and liver disease. In: Cytokines in Health and Disease, edited by Remick D and Friedland J (2nd ed.). New York: Dekker, 1997, p. 401-425.
11. Hill DB, Schmidt J, Shedlofsky S, Cohen D, and McClain CJ. In vitro tumor necrosis factor cytotoxicity in HepG2 liver cells. Hepatology 21: 1114-1119, 1995.
12. Honchel R, Ray MB, and Marsano L. Tumor necrosis factor in alcohol enhanced endotoxin liver injury. Alcohol Clin Exp Res 16: 665-669, 1992.
13. Iimuro Y, Gallucci RM, Luster MI, Kono H, and Thurman RG. Antibodies to tumor necrosis factor-α attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat. Hepatology 26: 1530-1537, 1997.
14. KB-independent IL-8 expression in human hepatocytes. Hepatology 38: 1178-1187, 2003.
15. Kamimura S and Tsukamoto H. Cytokine gene expression by Kupffer cells in experimental alcoholic liver disease. Hepatology 21: 1304-1309, 1995.
16. Leist M, Gantner F, Bohlinger I, Germann PG, Tiegs G, and Wendel A. Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-α requires transcriptional arrest. J Immunol 153: 1778-1788, 1994.
17. Lin A. Activation of the JNK signaling pathway: breaking the brake on apoptosis. Bioessays 25: 17-24, 2003.
18. Mato JM, Camara J, de Pas JF, Caballeria L, Coll S, Caballero A, Garcia-Buey L, Beltran J, Benita V, Caballeria J, Sola R, Morreno-Otero R, Barrao F, Martin-Duce A, Correa JA, Pares A, Barrao E, Garcia-Magaz I, Puerta JL, Moreno J, Boissard G, Ortiz P, Rodes J. S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double blind, multicenter clinical trial. J Hepatol 30: 1081-1089, 1999.
19. McClain CJ, Barve S, Deaciuc I, Kugelmas M, and Hill D. Cytokines in alcoholic liver disease. Semin Liver Dis 19: 205-219, 1999.
20. McClain CJ and Cohen DA. Increased tumor necrosis factor production by monocytes in alcoholic hepatitis. Hepatology 9: 349-351, 1989.
21. Menon KV, Stadheim L, Kamath PS, Wiesner RH, Gores GJ, Peine CJ, and Shah V. A pilot study of the safety and tolerability of etanercept in patients with alcoholic hepatitis. Am J Gastroenterol 99: 255-260, 2004.
22. Nanji AA, Zhao S, Sadrzadeh SM, and Waxman DJ. Use of reverse transcription-polymerase chain reaction to evaluate in vivo cytokine gene expression in rats fed ethanol for long periods. Hepatology 19:1483-1487, 1994.
23. Naveau S, Chollet-Martin S, Dharancy S, Mathurin P, Jouet P, Piquet MA, Davion T, Oberti F, Broët P, Emilie D. A double-blind randomized controlled trial of infliximab associated with prednisolone in acute alcoholic hepatitis. Hepatology 39: 1390-1397, 2004.
24. Pastorino JG and Hoek JB. Ethanol potentiates tumor necrosis factor-α cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition. Hepatology 31: 1141-1152, 2000.
25. Sen CK and Packer L. Antioxidant and redox regulation of gene transcription. FASEB J 10: 709-720, 1996.
26. Song Z, Zhou Z, Uriarte S, Wang L, Kang JY, Chen T, Barve S, and McClain CJ. S-adenosylhomocysteine sensitizes to tumor necrosis factor hepatotoxicity: A possible etiologic factor in alcoholic liver disease. Hepatology. In press.
27. KB. Science 274: 784-787, 1996.
28. Wu D and Cederbaum AL. Ethanol cytotoxicity to a transfected HepG2 cell line expressing human cytochrome P450 2E1. J Biol Chem 271: 1-6, 1996.
29. Yin M, Wheeler MD, Kono H, Bradford BU, Gallucci RM, Luster MI, and Thurman RG. Essential role of tumor necrosis factor-α in alcohol-induced liver injury in mice. Gastroenterology 117: 942-952, 1999.
30. Zhang Z, Bagby GJ, Stoltz D, Oliver P, Schwarzenberger PO, and Kolls JK. Prolonged ethanol treatment enhances lipopolysaccharide/phorbol myristate acetate-induced tumor necrosis factor-α production in human monocytic cells. Alcohol Clin Exp Res 25: 444-449, 2001.