Regulating excitability of peripheral afferents: Emerging ion channel targets

Nature Neuroscience

Volumn 17, Issue 2, 2014, Pages 153-163

  Waxman, Stephen G ^a,b   Zamponi, Gerald W ^c  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ACTIVATED CHLORIDE CHANNEL; CALCIUM CHANNEL; CALCIUM CHANNEL T TYPE; CHLORIDE CHANNEL; CYCLIC AMP DEPENDENT PROTEIN KINASE; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; POTASSIUM CHANNEL; SODIUM CHANNEL; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL;

ACTION POTENTIAL; AFTERHYPERPOLARIZATION; ALLELE; AMINO ACID SEQUENCE; ANALGESIA (SENSORY DYSFUNCTION); BURN; CALCIUM BINDING; CHANNELOPATHY; CHLORIDE CURRENT; CHRONIC PAIN; COLD SENSITIVITY; CONFUSION; CONGENITAL ANALGESIA; DEPOLARIZATION; DIPLOPIA; DRUG TARGETING; ERYTHROMELALGIA; EXCITABILITY; EXOCYTOSIS; EXPERIMENTAL NEUROPATHY; GAIN OF FUNCTION MUTATION; GENETIC ASSOCIATION; HEAT SENSITIVITY; HUMAN; HYPERALGESIA; HYPERSENSITIVITY; INFLAMMATION; INFLAMMATORY PAIN; INTERNALIZATION; LIMB AMPUTATION; MECHANORECEPTOR; MECHANOTRANSDUCTION; MEMBRANE POTENTIAL; MEMBRANE STEADY POTENTIAL; MISSENSE MUTATION; MYENTERIC PLEXUS; NERVE CELL; NERVE ENDING; NERVE FIBER; NEUROPATHIC PAIN; NEUROPATHY; NEUROTRANSMITTER RELEASE; NOCICEPTIVE PAIN; NODOSE GANGLION; NONHUMAN; PAIN; PERIPHERAL NERVE; PERIPHERAL NERVE INJURY; PERIPHERAL NEUROPATHY; PHENOTYPE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSYCHOGENIC PAIN; REPOLARIZATION; REVIEW; SENSORY NERVE; SENSORY NERVE CELL; SENSORY STIMULATION; SIGNAL TRANSDUCTION; SMALL FIBER NEUROPATHY; SODIUM CURRENT; SOMNOLENCE; SPINAL CORD DORSAL HORN; SPINAL CORD FUNCTION; SPINAL CORD INJURY; SYMPATHETIC GANGLION; SYNAPTIC TRANSMISSION; TRIGEMINUS GANGLION; UPREGULATION;

AFFERENT PATHWAYS; ANIMALS; HUMANS; ION CHANNELS; PAIN; PERIPHERAL NERVES;

EID: 84893801131     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3602     Document Type: Review

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