Gain-of-function Nav1.8 mutations in painful neuropathy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 47, 2012, Pages 19444-19449

  Faber, Catharina G ^a   Lauria, Giuseppe ^b   Merkies, Ingemar S J ^a,c   Cheng, Xiaoyang ^d,e   Han, Chongyang ^d,e   Ahn, Hye Sook ^d,e   Persson, Anna Karin ^d,e   Hoeijmakers, Janneke G J ^a   Gerrits, Monique M ^a   Pierro, Tiziana ^b   Lombardi, Raffaella ^b   Kapetis, Dimos ^b   Dib Hajj, Sulayman D ^d,e   Waxman, Stephen G ^d,e  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Istituto Ricovero Cura Carattere Scientifico Multimedica   (Italy)

^c Infection and Immunology   (Netherlands)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

Dorsal root ganglia; Patch clamp

Indexed keywords

SODIUM CHANNEL NAV1.8; SCN10A PROTEIN, HUMAN; SCN10A PROTEIN, MOUSE;

AGED; ALGORITHM; ARTICLE; DEPOLARIZATION; ELECTRIC POTENTIAL; FEMALE; GAIN OF FUNCTION MUTATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; NERVE EXCITABILITY; NERVE FIBER; PATHOGENICITY; PERIPHERAL NERVE; PERIPHERAL NEUROPATHY; PREDICTOR VARIABLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMALL FIBER NEUROPATHY; SPINAL GANGLION; VOLTAGE CLAMP; ADULT; AMINO ACID SUBSTITUTION; ANIMAL; CASE REPORT; ELECTROPHYSIOLOGY; GENETICS; METABOLISM; MOUSE; MUTATION; NEURALGIA; NUCLEOTIDE SEQUENCE; PATHOLOGY; PATHOPHYSIOLOGY;

ADULT; AGED; AMINO ACID SUBSTITUTION; ANIMALS; DNA MUTATIONAL ANALYSIS; ELECTROPHYSIOLOGICAL PHENOMENA; GANGLIA, SPINAL; HUMANS; MALE; MICE; MUTATION; NAV1.8 VOLTAGE-GATED SODIUM CHANNEL; NERVE FIBERS; NEURALGIA;

EID: 84869795443     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1216080109     Document Type: Article

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