A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura

Nature Medicine

Volumn 16, Issue 10, 2010, Pages 1157-1160

  Lafrenière, Ronald G ^a,b   Cader, M Zameel ^c,d   Poulin, Jean François ^b   Andres Enguix, Isabelle ^c   Simoneau, Maryse ^b   Gupta, Namrata ^b   Boisvert, Karine ^b   Lafrenière, François ^b   McLaughlan, Shannon ^b   Dubé, Marie Pierre ^e   Marcinkiewicz, Martin M ^f   Ramagopalan, Sreeram ^g   Ansorge, Olaf ^c   Brais, Bernard ^a   Sequeiros, Jorge ^h   Pereira Monteiro, Jose Maria ⁱ   Griffiths, Lyn R ^j   Tucker, Stephen J ^c   Ebers, George ^g   Rouleau, Guy A ^a,b  

^a NOTRE DAME HOSPITAL   (Canada)

^b Emerillon Therapeutics   (Canada)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^e UNIVERSITY OF MONTREAL   (Canada)

^f Department of Cytochem ^*  (Canada)

^g UNIVERSITY OF OXFORD   (United Kingdom)

^h UNIVERSITY OF PORTO   (Portugal)

ⁱ HOSPITAL DE SANTO ANTÓNIO   (Portugal)

^j GRIFFITH UNIVERSITY   (Australia)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MESSENGER RNA; TANDEM PORE DOMAIN POTASSIUM CHANNEL; TWIK RELATED SPINAL CORD POTASSIUM CHANNEL; UNCLASSIFIED DRUG; KCNK18 PROTEIN, HUMAN; POTASSIUM CHANNEL; TRIK PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENATURING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; DOWN REGULATION; ELECTROPHYSIOLOGY; EMBRYO; FRAMESHIFT MUTATION; GENE; GENE DELETION; GENE EXPRESSION; GENE SEQUENCE; GENOTYPE; HAPLOTYPE MAP; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; KCNK 18 GENE; LOSS OF FUNCTION MUTATION; MAJOR CLINICAL STUDY; MIGRAINE WITH AURA; MISSENSE MUTATION; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PATHOGENESIS; PEDIGREE; PENETRANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEGREGATION ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SITE DIRECTED MUTAGENESIS; SPINAL GANGLION; STELLATE GANGLION; SYMPATHETIC GANGLION; TRIGEMINUS GANGLION; WESTERN BLOTTING; ANIMAL; GENETIC LINKAGE; GENETICS; MUTATION; PHYSIOLOGY;

ANIMALS; GENETIC LINKAGE; HUMANS; MICE; MIGRAINE WITH AURA; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; POTASSIUM CHANNELS;

EID: 77957812064     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2216     Document Type: Article

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