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Volumn 10, Issue 1, 2014, Pages

Reengineering Redox Sensitive GFP to Measure Mycothiol Redox Potential of Mycobacterium tuberculosis during Infection

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; GLYCOPEPTIDE; GREEN FLUORESCENT PROTEIN; INOSITOL; MYCOTHIOL;

EID: 84893730144     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003902     Document Type: Article
Times cited : (161)

References (74)
  • 1
    • 77952326903 scopus 로고    scopus 로고
    • The population dynamics and control of tuberculosis
    • Dye C, Williams BG, (2010) The population dynamics and control of tuberculosis. Science 328: 856-861.
    • (2010) Science , vol.328 , pp. 856-861
    • Dye, C.1    Williams, B.G.2
  • 2
    • 67650164516 scopus 로고    scopus 로고
    • Mycobacterial survival strategies in the phagosome: defence against host stresses
    • Ehrt S, Schnappinger D, (2009) Mycobacterial survival strategies in the phagosome: defence against host stresses. Cell Microbiol 11: 1170-1178.
    • (2009) Cell Microbiol , vol.11 , pp. 1170-1178
    • Ehrt, S.1    Schnappinger, D.2
  • 4
    • 0033975318 scopus 로고    scopus 로고
    • Transient loss of resistance to pulmonary tuberculosis in p47(phox-/-) mice
    • Cooper AM, Segal BH, Frank AA, Holland SM, Orme IM, (2000) Transient loss of resistance to pulmonary tuberculosis in p47(phox-/-) mice. Infect Immun 68: 1231-1234.
    • (2000) Infect Immun , vol.68 , pp. 1231-1234
    • Cooper, A.M.1    Segal, B.H.2    Frank, A.A.3    Holland, S.M.4    Orme, I.M.5
  • 5
    • 44949109341 scopus 로고    scopus 로고
    • Susceptibility to mycobacterial infections in children with X-linked chronic granulomatous disease: a review of 17 patients living in a region endemic for tuberculosis
    • Lee PP, Chan KW, Jiang L, Chen T, Li C, et al. (2008) Susceptibility to mycobacterial infections in children with X-linked chronic granulomatous disease: a review of 17 patients living in a region endemic for tuberculosis. Pediatr Infect Dis J 27: 224-230.
    • (2008) Pediatr Infect Dis J , vol.27 , pp. 224-230
    • Lee, P.P.1    Chan, K.W.2    Jiang, L.3    Chen, T.4    Li, C.5
  • 6
    • 84866348007 scopus 로고    scopus 로고
    • Neutrophils exert protection in the early tuberculous granuloma by oxidative killing of mycobacteria phagocytosed from infected macrophages
    • Yang CT, Cambier CJ, Davis JM, Hall CJ, Crosier PS, et al. (2012) Neutrophils exert protection in the early tuberculous granuloma by oxidative killing of mycobacteria phagocytosed from infected macrophages. Cell Host Microbe 12: 301-312.
    • (2012) Cell Host Microbe , vol.12 , pp. 301-312
    • Yang, C.T.1    Cambier, C.J.2    Davis, J.M.3    Hall, C.J.4    Crosier, P.S.5
  • 8
    • 84868334611 scopus 로고    scopus 로고
    • The oxidation-sensing regulator (MosR) is a new redox-dependent transcription factor in Mycobacterium tuberculosis
    • Brugarolas P, Movahedzadeh F, Wang Y, Zhang N, Bartek IL, et al. (2012) The oxidation-sensing regulator (MosR) is a new redox-dependent transcription factor in Mycobacterium tuberculosis. J Biol Chem 287: 37703-37712.
    • (2012) J Biol Chem , vol.287 , pp. 37703-37712
    • Brugarolas, P.1    Movahedzadeh, F.2    Wang, Y.3    Zhang, N.4    Bartek, I.L.5
  • 9
    • 34547463011 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis WhiB3 responds to O2 and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival
    • Singh A, Guidry L, Narasimhulu KV, Mai D, Trombley J, et al. (2007) Mycobacterium tuberculosis WhiB3 responds to O2 and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival. Proc Natl Acad Sci U S A 104: 11562-11567.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 11562-11567
    • Singh, A.1    Guidry, L.2    Narasimhulu, K.V.3    Mai, D.4    Trombley, J.5
  • 10
    • 70149116303 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis WhiB3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response
    • Singh A, Crossman DK, Mai D, Guidry L, Voskuil MI, et al. (2009) Mycobacterium tuberculosis WhiB3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response. PLoS Pathog 5: e1000545.
    • (2009) PLoS Pathog , vol.5
    • Singh, A.1    Crossman, D.K.2    Mai, D.3    Guidry, L.4    Voskuil, M.I.5
  • 11
    • 84866029444 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis WhiB4 regulates oxidative stress response to modulate survival and dissemination in vivo
    • Chawla M, Parikh P, Saxena A, Munshi M, Mehta M, et al. (2012) Mycobacterium tuberculosis WhiB4 regulates oxidative stress response to modulate survival and dissemination in vivo. Mol Microbiol 85: 1148-1165.
    • (2012) Mol Microbiol , vol.85 , pp. 1148-1165
    • Chawla, M.1    Parikh, P.2    Saxena, A.3    Munshi, M.4    Mehta, M.5
  • 12
    • 0242521392 scopus 로고    scopus 로고
    • RshA, an anti-sigma factor that regulates the activity of the mycobacterial stress response sigma factor SigH
    • Song T, Dove SL, Lee KH, Husson RN, (2003) RshA, an anti-sigma factor that regulates the activity of the mycobacterial stress response sigma factor SigH. Mol Microbiol 50: 949-959.
    • (2003) Mol Microbiol , vol.50 , pp. 949-959
    • Song, T.1    Dove, S.L.2    Lee, K.H.3    Husson, R.N.4
  • 13
    • 0034977241 scopus 로고    scopus 로고
    • Tuberculosis: latency and reactivation
    • Flynn JL, Chan J, (2001) Tuberculosis: latency and reactivation. Infect Immun 69: 4195-4201.
    • (2001) Infect Immun , vol.69 , pp. 4195-4201
    • Flynn, J.L.1    Chan, J.2
  • 15
    • 0032830132 scopus 로고    scopus 로고
    • Evidence for free radical formation during the oxidation of 2′-7′-dichlorofluorescin to the fluorescent dye 2′-7′-dichlorofluorescein by horseradish peroxidase: possible implications for oxidative stress measurements
    • Rota C, Chignell CF, Mason RP, (1999) Evidence for free radical formation during the oxidation of 2′-7′-dichlorofluorescin to the fluorescent dye 2′-7′-dichlorofluorescein by horseradish peroxidase: possible implications for oxidative stress measurements. Free Radic Biol Med 27: 873-881.
    • (1999) Free Radic Biol Med , vol.27 , pp. 873-881
    • Rota, C.1    Chignell, C.F.2    Mason, R.P.3
  • 16
    • 1342289237 scopus 로고    scopus 로고
    • Methods for detection of reactive metabolites of oxygen and nitrogen: in vitro and in vivo considerations
    • Tarpey MM, Wink DA, Grisham MB, (2004) Methods for detection of reactive metabolites of oxygen and nitrogen: in vitro and in vivo considerations. Am J Physiol Regul Integr Comp Physiol 286: R431-444.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286
    • Tarpey, M.M.1    Wink, D.A.2    Grisham, M.B.3
  • 17
    • 77954356493 scopus 로고    scopus 로고
    • Fluorescent protein-based redox probes
    • Meyer AJ, Dick TP, (2010) Fluorescent protein-based redox probes. Antioxid Redox Signal 13: 621-650.
    • (2010) Antioxid Redox Signal , vol.13 , pp. 621-650
    • Meyer, A.J.1    Dick, T.P.2
  • 19
    • 58949091991 scopus 로고    scopus 로고
    • Mycothiol: synthesis, biosynthesis and biological functions of the major low molecular weight thiol in actinomycetes
    • Jothivasan VK, Hamilton CJ, (2008) Mycothiol: synthesis, biosynthesis and biological functions of the major low molecular weight thiol in actinomycetes. Nat Prod Rep 25: 1091-1117.
    • (2008) Nat Prod Rep , vol.25 , pp. 1091-1117
    • Jothivasan, V.K.1    Hamilton, C.J.2
  • 20
    • 0242407452 scopus 로고    scopus 로고
    • Mycothiol is essential for growth of Mycobacterium tuberculosis Erdman
    • Sareen D, Newton GL, Fahey RC, Buchmeier NA, (2003) Mycothiol is essential for growth of Mycobacterium tuberculosis Erdman. J Bacteriol 185: 6736-6740.
    • (2003) J Bacteriol , vol.185 , pp. 6736-6740
    • Sareen, D.1    Newton, G.L.2    Fahey, R.C.3    Buchmeier, N.A.4
  • 21
    • 0037347862 scopus 로고    scopus 로고
    • Association of mycothiol with protection of Mycobacterium tuberculosis from toxic oxidants and antibiotics
    • Buchmeier NA, Newton GL, Koledin T, Fahey RC, (2003) Association of mycothiol with protection of Mycobacterium tuberculosis from toxic oxidants and antibiotics. Mol Microbiol 47: 1723-1732.
    • (2003) Mol Microbiol , vol.47 , pp. 1723-1732
    • Buchmeier, N.A.1    Newton, G.L.2    Koledin, T.3    Fahey, R.C.4
  • 22
    • 0842344106 scopus 로고    scopus 로고
    • Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators
    • Hanson GT, Aggeler R, Oglesbee D, Cannon M, Capaldi RA, et al. (2004) Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators. J Biol Chem 279: 13044-13053.
    • (2004) J Biol Chem , vol.279 , pp. 13044-13053
    • Hanson, G.T.1    Aggeler, R.2    Oglesbee, D.3    Cannon, M.4    Capaldi, R.A.5
  • 23
    • 36349007756 scopus 로고    scopus 로고
    • Redox-sensitive GFP in Arabidopsis thaliana is a quantitative biosensor for the redox potential of the cellular glutathione redox buffer
    • Meyer AJ, Brach T, Marty L, Kreye S, Rouhier N, et al. (2007) Redox-sensitive GFP in Arabidopsis thaliana is a quantitative biosensor for the redox potential of the cellular glutathione redox buffer. Plant J 52: 973-986.
    • (2007) Plant J , vol.52 , pp. 973-986
    • Meyer, A.J.1    Brach, T.2    Marty, L.3    Kreye, S.4    Rouhier, N.5
  • 24
    • 44449090114 scopus 로고    scopus 로고
    • Real-time imaging of the intracellular glutathione redox potential
    • Gutscher M, Pauleau AL, Marty L, Brach T, Wabnitz GH, et al. (2008) Real-time imaging of the intracellular glutathione redox potential. Nat Methods 5: 553-559.
    • (2008) Nat Methods , vol.5 , pp. 553-559
    • Gutscher, M.1    Pauleau, A.L.2    Marty, L.3    Brach, T.4    Wabnitz, G.H.5
  • 25
    • 84871808410 scopus 로고    scopus 로고
    • Mycoredoxin-1 is one of the missing links in the oxidative stress defence mechanism of Mycobacteria
    • Van Laer K, Buts L, Foloppe N, Vertommen D, Van Belle K, et al. (2012) Mycoredoxin-1 is one of the missing links in the oxidative stress defence mechanism of Mycobacteria. Mol Microbiol 86: 787-804.
    • (2012) Mol Microbiol , vol.86 , pp. 787-804
    • Van Laer, K.1    Buts, L.2    Foloppe, N.3    Vertommen, D.4    Van Belle, K.5
  • 26
    • 0036840388 scopus 로고    scopus 로고
    • Mycothiol-deficient Mycobacterium smegmatis mutants are hypersensitive to alkylating agents, free radicals, and antibiotics
    • Rawat M, Newton GL, Ko M, Martinez GJ, Fahey RC, et al. (2002) Mycothiol-deficient Mycobacterium smegmatis mutants are hypersensitive to alkylating agents, free radicals, and antibiotics. Antimicrob Agents Chemother 46: 3348-3355.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 3348-3355
    • Rawat, M.1    Newton, G.L.2    Ko, M.3    Martinez, G.J.4    Fahey, R.C.5
  • 27
    • 0033533411 scopus 로고    scopus 로고
    • Expression, purification, and characterization of Mycobacterium tuberculosis mycothione reductase
    • Patel MP, Blanchard JS, (1999) Expression, purification, and characterization of Mycobacterium tuberculosis mycothione reductase. Biochemistry 38: 11827-11833.
    • (1999) Biochemistry , vol.38 , pp. 11827-11833
    • Patel, M.P.1    Blanchard, J.S.2
  • 28
    • 67651064692 scopus 로고    scopus 로고
    • Dequalinium, a new inhibitor of Mycobacterium tuberculosis mycothiol ligase identified by high-throughput screening
    • Gutierrez-Lugo MT, Baker H, Shiloach J, Boshoff H, Bewley CA, (2009) Dequalinium, a new inhibitor of Mycobacterium tuberculosis mycothiol ligase identified by high-throughput screening. J Biomol Screen 14: 643-652.
    • (2009) J Biomol Screen , vol.14 , pp. 643-652
    • Gutierrez-Lugo, M.T.1    Baker, H.2    Shiloach, J.3    Boshoff, H.4    Bewley, C.A.5
  • 29
    • 0035890009 scopus 로고    scopus 로고
    • Analysis of the inhibition of mammalian thioredoxin, thioredoxin reductase, and glutaredoxin by cis-diamminedichloroplatinum (II) and its major metabolite, the glutathione-platinum complex
    • Arner ES, Nakamura H, Sasada T, Yodoi J, Holmgren A, et al. (2001) Analysis of the inhibition of mammalian thioredoxin, thioredoxin reductase, and glutaredoxin by cis-diamminedichloroplatinum (II) and its major metabolite, the glutathione-platinum complex. Free Radic Biol Med 31: 1170-1178.
    • (2001) Free Radic Biol Med , vol.31 , pp. 1170-1178
    • Arner, E.S.1    Nakamura, H.2    Sasada, T.3    Yodoi, J.4    Holmgren, A.5
  • 30
    • 0031026392 scopus 로고    scopus 로고
    • Cytosolic and mitochondrial systems for NADH- and NADPH-dependent reduction of alpha-lipoic acid
    • Haramaki N, Han D, Handelman GJ, Tritschler HJ, Packer L, (1997) Cytosolic and mitochondrial systems for NADH- and NADPH-dependent reduction of alpha-lipoic acid. Free Radic Biol Med 22: 535-542.
    • (1997) Free Radic Biol Med , vol.22 , pp. 535-542
    • Haramaki, N.1    Han, D.2    Handelman, G.J.3    Tritschler, H.J.4    Packer, L.5
  • 31
    • 34548781274 scopus 로고    scopus 로고
    • Comparative analysis of mutants in the mycothiol biosynthesis pathway in Mycobacterium smegmatis
    • Rawat M, Johnson C, Cadiz V, Av-Gay Y, (2007) Comparative analysis of mutants in the mycothiol biosynthesis pathway in Mycobacterium smegmatis. Biochem Biophys Res Commun 363: 71-76.
    • (2007) Biochem Biophys Res Commun , vol.363 , pp. 71-76
    • Rawat, M.1    Johnson, C.2    Cadiz, V.3    Av-Gay, Y.4
  • 32
    • 0032779309 scopus 로고    scopus 로고
    • A mycobacterial extracytoplasmic sigma factor involved in survival following heat shock and oxidative stress
    • Fernandes ND, Wu QL, Kong D, Puyang X, Garg S, et al. (1999) A mycobacterial extracytoplasmic sigma factor involved in survival following heat shock and oxidative stress. J Bacteriol 181: 4266-4274.
    • (1999) J Bacteriol , vol.181 , pp. 4266-4274
    • Fernandes, N.D.1    Wu, Q.L.2    Kong, D.3    Puyang, X.4    Garg, S.5
  • 33
    • 0034805644 scopus 로고    scopus 로고
    • The alternative sigma factor SigH regulates major components of oxidative and heat stress responses in Mycobacterium tuberculosis
    • Raman S, Song T, Puyang X, Bardarov S, Jacobs WR Jr, et al. (2001) The alternative sigma factor SigH regulates major components of oxidative and heat stress responses in Mycobacterium tuberculosis. J Bacteriol 183: 6119-6125.
    • (2001) J Bacteriol , vol.183 , pp. 6119-6125
    • Raman, S.1    Song, T.2    Puyang, X.3    Bardarov, S.4    Jacobs Jr., W.R.5
  • 34
    • 0037062452 scopus 로고    scopus 로고
    • Reduced immunopathology and mortality despite tissue persistence in a Mycobacterium tuberculosis mutant lacking alternative sigma factor, SigH
    • Kaushal D, Schroeder BG, Tyagi S, Yoshimatsu T, Scott C, et al. (2002) Reduced immunopathology and mortality despite tissue persistence in a Mycobacterium tuberculosis mutant lacking alternative sigma factor, SigH. Proc Natl Acad Sci U S A 99: 8330-8335.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 8330-8335
    • Kaushal, D.1    Schroeder, B.G.2    Tyagi, S.3    Yoshimatsu, T.4    Scott, C.5
  • 35
    • 27144496052 scopus 로고    scopus 로고
    • A mycothiol synthase mutant of Mycobacterium smegmatis produces novel thiols and has an altered thiol redox status
    • Newton GL, Ta P, Fahey RC, (2005) A mycothiol synthase mutant of Mycobacterium smegmatis produces novel thiols and has an altered thiol redox status. J Bacteriol 187: 7309-7316.
    • (2005) J Bacteriol , vol.187 , pp. 7309-7316
    • Newton, G.L.1    Ta, P.2    Fahey, R.C.3
  • 36
    • 79955378872 scopus 로고    scopus 로고
    • Organic hydroperoxide resistance protein and ergothioneine compensate for loss of mycothiol in Mycobacterium smegmatis mutants
    • Ta P, Buchmeier N, Newton GL, Rawat M, Fahey RC, (2011) Organic hydroperoxide resistance protein and ergothioneine compensate for loss of mycothiol in Mycobacterium smegmatis mutants. J Bacteriol 193: 1981-1990.
    • (2011) J Bacteriol , vol.193 , pp. 1981-1990
    • Ta, P.1    Buchmeier, N.2    Newton, G.L.3    Rawat, M.4    Fahey, R.C.5
  • 37
    • 80051546929 scopus 로고    scopus 로고
    • Mass Spectrometric Analysis of Mycothiol levels in Wild-Type and Mycothiol Disulfide Reductase Mutant Mycobacterium smegmatis
    • Holsclaw CM, Muse WB 3rd, Carroll KS, Leary JA, (2011) Mass Spectrometric Analysis of Mycothiol levels in Wild-Type and Mycothiol Disulfide Reductase Mutant Mycobacterium smegmatis. Int J Mass Spectrom 305: 151-156.
    • (2011) Int J Mass Spectrom , vol.305 , pp. 151-156
    • Holsclaw, C.M.1    Muse 3rd, W.B.2    Carroll, K.S.3    Leary, J.A.4
  • 38
    • 82955227412 scopus 로고    scopus 로고
    • In vivo mapping of hydrogen peroxide and oxidized glutathione reveals chemical and regional specificity of redox homeostasis
    • Albrecht SC, Barata AG, Grosshans J, Teleman AA, Dick TP, (2011) In vivo mapping of hydrogen peroxide and oxidized glutathione reveals chemical and regional specificity of redox homeostasis. Cell Metab 14: 819-829.
    • (2011) Cell Metab , vol.14 , pp. 819-829
    • Albrecht, S.C.1    Barata, A.G.2    Grosshans, J.3    Teleman, A.A.4    Dick, T.P.5
  • 39
    • 33745518017 scopus 로고    scopus 로고
    • Mycothiol-dependent mycobacterial response to oxidative stress
    • Ung KS, Av-Gay Y, (2006) Mycothiol-dependent mycobacterial response to oxidative stress. FEBS Lett 580: 2712-2716.
    • (2006) FEBS Lett , vol.580 , pp. 2712-2716
    • Ung, K.S.1    Av-Gay, Y.2
  • 40
    • 0026549480 scopus 로고
    • Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages
    • Chan J, Xing Y, Magliozzo RS, Bloom BR, (1992) Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages. J Exp Med 175: 1111-1122.
    • (1992) J Exp Med , vol.175 , pp. 1111-1122
    • Chan, J.1    Xing, Y.2    Magliozzo, R.S.3    Bloom, B.R.4
  • 41
    • 0028936417 scopus 로고
    • Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis
    • Chan J, Tanaka K, Carroll D, Flynn J, Bloom BR, (1995) Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis. Infect Immun 63: 736-740.
    • (1995) Infect Immun , vol.63 , pp. 736-740
    • Chan, J.1    Tanaka, K.2    Carroll, D.3    Flynn, J.4    Bloom, B.R.5
  • 42
    • 84864044868 scopus 로고    scopus 로고
    • Linking the transcriptional profiles and the physiological states of Mycobacterium tuberculosis during an extended intracellular infection
    • Rohde KH, Veiga DF, Caldwell S, Balazsi G, Russell DG, (2012) Linking the transcriptional profiles and the physiological states of Mycobacterium tuberculosis during an extended intracellular infection. PLoS Pathog 8: e1002769.
    • (2012) PLoS Pathog , vol.8
    • Rohde, K.H.1    Veiga, D.F.2    Caldwell, S.3    Balazsi, G.4    Russell, D.G.5
  • 43
    • 84880224426 scopus 로고    scopus 로고
    • Physiological roles of mycothiol in detoxification and tolerance to multiple poisonous chemicals in Corynebacterium glutamicum
    • Liu YB, Long MX, Yin YJ, Si MR, Zhang L, et al. (2013) Physiological roles of mycothiol in detoxification and tolerance to multiple poisonous chemicals in Corynebacterium glutamicum. Arch Microbiol 195: 419-29.
    • (2013) Arch Microbiol , vol.195 , pp. 419-429
    • Liu, Y.B.1    Long, M.X.2    Yin, Y.J.3    Si, M.R.4    Zhang, L.5
  • 44
    • 4444241900 scopus 로고    scopus 로고
    • Targeted mutagenesis of the Mycobacterium smegmatis mca gene, encoding a mycothiol-dependent detoxification protein
    • Rawat M, Uppal M, Newton G, Steffek M, Fahey RC, et al. (2004) Targeted mutagenesis of the Mycobacterium smegmatis mca gene, encoding a mycothiol-dependent detoxification protein. J Bacteriol 186: 6050-6058.
    • (2004) J Bacteriol , vol.186 , pp. 6050-6058
    • Rawat, M.1    Uppal, M.2    Newton, G.3    Steffek, M.4    Fahey, R.C.5
  • 45
    • 79959226734 scopus 로고    scopus 로고
    • Precise null deletion mutations of the mycothiol synthesis genes reveal their role in isoniazid and ethionamide resistance in Mycobacterium smegmatis
    • Xu X, Vilcheze C, Av-Gay Y, Gomez-Velasco A, Jacobs WR Jr, (2011) Precise null deletion mutations of the mycothiol synthesis genes reveal their role in isoniazid and ethionamide resistance in Mycobacterium smegmatis. Antimicrob Agents Chemother 55: 3133-3139.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 3133-3139
    • Xu, X.1    Vilcheze, C.2    Av-Gay, Y.3    Gomez-Velasco, A.4    Jacobs Jr., W.R.5
  • 46
    • 78650654727 scopus 로고    scopus 로고
    • Molecular investigation of resistance to the antituberculous drug ethionamide in multidrug-resistant clinical isolates of Mycobacterium tuberculosis
    • Brossier F, Veziris N, Truffot-Pernot C, Jarlier V, Sougakoff W, (2011) Molecular investigation of resistance to the antituberculous drug ethionamide in multidrug-resistant clinical isolates of Mycobacterium tuberculosis. Antimicrob Agents Chemother 55: 355-360.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 355-360
    • Brossier, F.1    Veziris, N.2    Truffot-Pernot, C.3    Jarlier, V.4    Sougakoff, W.5
  • 47
    • 79953218013 scopus 로고    scopus 로고
    • Reduction of clofazimine by mycobacterial type 2 NADH:quinone oxidoreductase: a pathway for the generation of bactericidal levels of reactive oxygen species
    • Yano T, Kassovska-Bratinova S, Teh JS, Winkler J, Sullivan K, et al. (2011) Reduction of clofazimine by mycobacterial type 2 NADH:quinone oxidoreductase: a pathway for the generation of bactericidal levels of reactive oxygen species. J Biol Chem 286: 10276-10287.
    • (2011) J Biol Chem , vol.286 , pp. 10276-10287
    • Yano, T.1    Kassovska-Bratinova, S.2    Teh, J.S.3    Winkler, J.4    Sullivan, K.5
  • 49
    • 79953279193 scopus 로고    scopus 로고
    • Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism
    • Adams KN, Takaki K, Connolly LE, Wiedenhoft H, Winglee K, et al. (2011) Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism. Cell 145: 39-53.
    • (2011) Cell , vol.145 , pp. 39-53
    • Adams, K.N.1    Takaki, K.2    Connolly, L.E.3    Wiedenhoft, H.4    Winglee, K.5
  • 50
    • 0035397672 scopus 로고    scopus 로고
    • An industrial application of multiparameter flow cytometry: assessment of cell physiological state and its application to the study of microbial fermentations
    • Hewitt CJ, Nebe-Von-Caron G, (2001) An industrial application of multiparameter flow cytometry: assessment of cell physiological state and its application to the study of microbial fermentations. Cytometry 44: 179-187.
    • (2001) Cytometry , vol.44 , pp. 179-187
    • Hewitt, C.J.1    Nebe-Von-Caron, G.2
  • 51
    • 70450227216 scopus 로고    scopus 로고
    • Proximity-based protein thiol oxidation by H2O2-scavenging peroxidases
    • Gutscher M, Sobotta MC, Wabnitz GH, Ballikaya S, Meyer AJ, et al. (2009) Proximity-based protein thiol oxidation by H2O2-scavenging peroxidases. J Biol Chem 284: 31532-31540.
    • (2009) J Biol Chem , vol.284 , pp. 31532-31540
    • Gutscher, M.1    Sobotta, M.C.2    Wabnitz, G.H.3    Ballikaya, S.4    Meyer, A.J.5
  • 52
    • 80052050200 scopus 로고    scopus 로고
    • Importance of phagosomal functionality for growth restriction of Mycobacterium tuberculosis in primary human macrophages
    • Welin A, Raffetseder J, Eklund D, Stendahl O, Lerm M, (2011) Importance of phagosomal functionality for growth restriction of Mycobacterium tuberculosis in primary human macrophages. J Innate Immun 3: 508-518.
    • (2011) J Innate Immun , vol.3 , pp. 508-518
    • Welin, A.1    Raffetseder, J.2    Eklund, D.3    Stendahl, O.4    Lerm, M.5
  • 53
    • 0029905151 scopus 로고    scopus 로고
    • The Mycobacterium tuberculosis phagosome interacts with early endosomes and is accessible to exogenously administered transferrin
    • Clemens DL, Horwitz MA, (1996) The Mycobacterium tuberculosis phagosome interacts with early endosomes and is accessible to exogenously administered transferrin. J Exp Med 184: 1349-1355.
    • (1996) J Exp Med , vol.184 , pp. 1349-1355
    • Clemens, D.L.1    Horwitz, M.A.2
  • 55
    • 77957671514 scopus 로고    scopus 로고
    • Functional genetic diversity among Mycobacterium tuberculosis complex clinical isolates: delineation of conserved core and lineage-specific transcriptomes during intracellular survival
    • Homolka S, Niemann S, Russell DG, Rohde KH, (2010) Functional genetic diversity among Mycobacterium tuberculosis complex clinical isolates: delineation of conserved core and lineage-specific transcriptomes during intracellular survival. PLoS Pathog 6: e1000988.
    • (2010) PLoS Pathog , vol.6
    • Homolka, S.1    Niemann, S.2    Russell, D.G.3    Rohde, K.H.4
  • 56
    • 84863213626 scopus 로고    scopus 로고
    • Strain specific transcriptional response in Mycobacterium tuberculosis infected macrophages
    • Koo MS, Subbian S, Kaplan G, (2012) Strain specific transcriptional response in Mycobacterium tuberculosis infected macrophages. Cell Commun Signal 10: 2.
    • (2012) Cell Commun Signal , vol.10 , pp. 2
    • Koo, M.S.1    Subbian, S.2    Kaplan, G.3
  • 57
    • 0032944213 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis catalase and peroxidase activities and resistance to oxidative killing in human monocytes in vitro
    • Manca C, Paul S, Barry CE 3rd, Freedman VH, Kaplan G, (1999) Mycobacterium tuberculosis catalase and peroxidase activities and resistance to oxidative killing in human monocytes in vitro. Infect Immun 67: 74-79.
    • (1999) Infect Immun , vol.67 , pp. 74-79
    • Manca, C.1    Paul, S.2    Barry 3rd, C.E.3    Freedman, V.H.4    Kaplan, G.5
  • 58
    • 84863090275 scopus 로고    scopus 로고
    • Resistance to first-line anti-TB drugs is associated with reduced nitric oxide susceptibility in Mycobacterium tuberculosis
    • Idh J, Mekonnen M, Abate E, Wedajo W, Werngren J, et al. (2012) Resistance to first-line anti-TB drugs is associated with reduced nitric oxide susceptibility in Mycobacterium tuberculosis. PLoS One 7: e39891.
    • (2012) PLoS One , vol.7
    • Idh, J.1    Mekonnen, M.2    Abate, E.3    Wedajo, W.4    Werngren, J.5
  • 59
    • 34548213103 scopus 로고    scopus 로고
    • A common mechanism of cellular death induced by bactericidal antibiotics
    • Kohanski MA, Dwyer DJ, Hayete B, Lawrence CA, Collins JJ, (2007) A common mechanism of cellular death induced by bactericidal antibiotics. Cell 130: 797-810.
    • (2007) Cell , vol.130 , pp. 797-810
    • Kohanski, M.A.1    Dwyer, D.J.2    Hayete, B.3    Lawrence, C.A.4    Collins, J.J.5
  • 60
    • 70349816733 scopus 로고    scopus 로고
    • Role of reactive oxygen species in antibiotic action and resistance
    • Dwyer DJ, Kohanski MA, Collins JJ, (2009) Role of reactive oxygen species in antibiotic action and resistance. Curr Opin Microbiol 12: 482-489.
    • (2009) Curr Opin Microbiol , vol.12 , pp. 482-489
    • Dwyer, D.J.1    Kohanski, M.A.2    Collins, J.J.3
  • 61
    • 84873587763 scopus 로고    scopus 로고
    • Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production
    • Brynildsen MP, Winkler JA, Spina CS, Macdonald IC, Collins JJ, (2013) Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production. Nat Biotechnol 31: 160-165.
    • (2013) Nat Biotechnol , vol.31 , pp. 160-165
    • Brynildsen, M.P.1    Winkler, J.A.2    Spina, C.S.3    Macdonald, I.C.4    Collins, J.J.5
  • 62
    • 84874720377 scopus 로고    scopus 로고
    • Killing by bactericidal antibiotics does not depend on reactive oxygen species
    • Keren I, Wu Y, Inocencio J, Mulcahy LR, Lewis K, (2013) Killing by bactericidal antibiotics does not depend on reactive oxygen species. Science 339: 1213-1216.
    • (2013) Science , vol.339 , pp. 1213-1216
    • Keren, I.1    Wu, Y.2    Inocencio, J.3    Mulcahy, L.R.4    Lewis, K.5
  • 63
    • 84874695302 scopus 로고    scopus 로고
    • Cell death from antibiotics without the involvement of reactive oxygen species
    • Liu Y, Imlay JA, (2013) Cell death from antibiotics without the involvement of reactive oxygen species. Science 339: 1210-1213.
    • (2013) Science , vol.339 , pp. 1210-1213
    • Liu, Y.1    Imlay, J.A.2
  • 65
    • 84861180818 scopus 로고    scopus 로고
    • Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action
    • Kim JJ, Lee HM, Shin DM, Kim W, Yuk JM, et al. (2012) Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action. Cell Host Microbe 11: 457-468.
    • (2012) Cell Host Microbe , vol.11 , pp. 457-468
    • Kim, J.J.1    Lee, H.M.2    Shin, D.M.3    Kim, W.4    Yuk, J.M.5
  • 66
    • 49249132882 scopus 로고    scopus 로고
    • Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis
    • Vilcheze C, Av-Gay Y, Attarian R, Liu Z, Hazbon MH, et al. (2008) Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis. Mol Microbiol 69: 1316-1329.
    • (2008) Mol Microbiol , vol.69 , pp. 1316-1329
    • Vilcheze, C.1    Av-Gay, Y.2    Attarian, R.3    Liu, Z.4    Hazbon, M.H.5
  • 68
    • 46249108568 scopus 로고    scopus 로고
    • Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates
    • Via LE, Lin PL, Ray SM, Carrillo J, Allen SS, et al. (2008) Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates. Infect Immun 76: 2333-2340.
    • (2008) Infect Immun , vol.76 , pp. 2333-2340
    • Via, L.E.1    Lin, P.L.2    Ray, S.M.3    Carrillo, J.4    Allen, S.S.5
  • 69
    • 50349099789 scopus 로고    scopus 로고
    • Biosynthesis and recycling of nicotinamide cofactors in Mycobacterium tuberculosis. An essential role for NAD in nonreplicating bacilli
    • Boshoff HI, Xu X, Tahlan K, Dowd CS, Pethe K, et al. (2008) Biosynthesis and recycling of nicotinamide cofactors in Mycobacterium tuberculosis. An essential role for NAD in nonreplicating bacilli. J Biol Chem 283: 19329-19341.
    • (2008) J Biol Chem , vol.283 , pp. 19329-19341
    • Boshoff, H.I.1    Xu, X.2    Tahlan, K.3    Dowd, C.S.4    Pethe, K.5
  • 70
    • 84865540183 scopus 로고    scopus 로고
    • Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques
    • Lin PL, Dartois V, Johnston PJ, Janssen C, Via L, et al. (2012) Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques. Proc Natl Acad Sci U S A 109: 14188-14193.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 14188-14193
    • Lin, P.L.1    Dartois, V.2    Johnston, P.J.3    Janssen, C.4    Via, L.5
  • 72
    • 84869077772 scopus 로고    scopus 로고
    • The Surprising Diversity of Mycobacterium tuberculosis: Change You Can Believe In
    • Fortune SM, (2012) The Surprising Diversity of Mycobacterium tuberculosis: Change You Can Believe In. J Infect Dis 206: 1642-1644.
    • (2012) J Infect Dis , vol.206 , pp. 1642-1644
    • Fortune, S.M.1
  • 73
    • 0036081333 scopus 로고    scopus 로고
    • Macrophage-induced genes of Legionella pneumophila: protection from reactive intermediates and solute imbalance during intracellular growth
    • Rankin S, Li Z, Isberg RR, (2002) Macrophage-induced genes of Legionella pneumophila: protection from reactive intermediates and solute imbalance during intracellular growth. Infect Immun 70: 3637-3648.
    • (2002) Infect Immun , vol.70 , pp. 3637-3648
    • Rankin, S.1    Li, Z.2    Isberg, R.R.3
  • 74
    • 33746622429 scopus 로고    scopus 로고
    • Dissecting virulence pathways of Mycobacterium tuberculosis through protein-protein association
    • Singh A, Mai D, Kumar A, Steyn AJ, (2006) Dissecting virulence pathways of Mycobacterium tuberculosis through protein-protein association. Proc Natl Acad Sci U S A 103: 11346-11351.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 11346-11351
    • Singh, A.1    Mai, D.2    Kumar, A.3    Steyn, A.J.4


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