메뉴 건너뛰기




Volumn 31, Issue 2, 2013, Pages 160-165

Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-BACTERIAL ACTIVITY; ANTIBIOTIC ACTIVITY; E. COLI; ENSEMBLE APPROACHES; FLUX DISTRIBUTIONS; GLOBAL PUBLIC HEALTH; IN-SILICO; METABOLIC MODELS; METABOLIC NETWORK; NOVEL STRATEGIES; OXIDATIVE ATTACK; REACTIVE OXYGEN SPECIES;

EID: 84873587763     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.2458     Document Type: Article
Times cited : (369)

References (36)
  • 1
    • 59449088862 scopus 로고    scopus 로고
    • Antibiotic-resistant bugs in the 21st century - A clinical super-challenge
    • Arias, C.A. & Murray, B.E. Antibiotic-resistant bugs in the 21st century-a clinical super-challenge. N. Engl. J. Med. 360, 439-443 (2009).
    • (2009) N. Engl. J. Med , vol.360 , pp. 439-443
    • Arias, C.A.1    Murray, B.E.2
  • 2
    • 84859958491 scopus 로고    scopus 로고
    • Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics
    • Foti, J.J., Devadoss, B., Winkler, J.A., Collins, J.J. & Walker, G.C. Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics. Science 336, 315-319 (2012).
    • (2012) Science , vol.336 , pp. 315-319
    • Foti, J.J.1    Devadoss, B.2    Winkler, J.A.3    Collins, J.J.4    Walker, G.C.5
  • 3
    • 34548213103 scopus 로고    scopus 로고
    • A common mechanism of cellular death induced by bactericidal antibiotics
    • Kohanski, M.A., Dwyer, D.J., Hayete, B., Lawrence, C.A. & Collins, J.J. A common mechanism of cellular death induced by bactericidal antibiotics. Cell 130, 797-810 (2007).
    • (2007) Cell , vol.130 , pp. 797-810
    • Kohanski, M.A.1    Dwyer, D.J.2    Hayete, B.3    Lawrence, C.A.4    Collins, J.J.5
  • 4
    • 55449126342 scopus 로고    scopus 로고
    • Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death
    • Kohanski, M.A., Dwyer, D.J., Wierzbowski, J., Cottarel, G. & Collins, J.J. Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death. Cell 135, 679-690 (2008).
    • (2008) Cell , vol.135 , pp. 679-690
    • Kohanski, M.A.1    Dwyer, D.J.2    Wierzbowski, J.3    Cottarel, G.4    Collins, J.J.5
  • 5
    • 0022683672 scopus 로고
    • Isolation of superoxide dismutase mutants in Escherichia coli: Is superoxide dismutase necessary for aerobic life?
    • Carlioz, A. & Touati, D. Isolation of superoxide dismutase mutants in Escherichia coli: is superoxide dismutase necessary for aerobic life? EMBO J. 5, 623-630 (1986).
    • (1986) EMBO J , vol.5 , pp. 623-630
    • Carlioz, A.1    Touati, D.2
  • 6
    • 0021325098 scopus 로고
    • Isolation of catalase-deficient Escherichia coli mutants and genetic mapping of katE, a locus that affects catalase activity
    • Loewen, P.C. Isolation of catalase-deficient Escherichia coli mutants and genetic mapping of katE, a locus that affects catalase activity. J. Bacteriol. 157, 622-626 (1984).
    • (1984) J. Bacteriol , vol.157 , pp. 622-626
    • Loewen, P.C.1
  • 7
    • 33947247352 scopus 로고    scopus 로고
    • Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli
    • Dwyer, D.J., Kohanski, M.A., Hayete, B. & Collins, J.J. Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli. Mol. Syst. Biol. 3, 91 (2007).
    • (2007) Mol. Syst. Biol , vol.3 , pp. 91
    • Dwyer, D.J.1    Kohanski, M.A.2    Hayete, B.3    Collins, J.J.4
  • 8
    • 67650299991 scopus 로고    scopus 로고
    • Redundant hydrogen peroxide scavengers contribute to Salmonella virulence and oxidative stress resistance
    • Hebrard, M., Viala, J.P., Meresse, S., Barras, F. & Aussel, L. Redundant hydrogen peroxide scavengers contribute to Salmonella virulence and oxidative stress resistance. J. Bacteriol. 191, 4605-4614 (2009).
    • (2009) J. Bacteriol , vol.191 , pp. 4605-4614
    • Hebrard, M.1    Viala, J.P.2    Meresse, S.3    Barras, F.4    Aussel, L.5
  • 9
    • 40449088993 scopus 로고    scopus 로고
    • A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence
    • Liu, C.I. et al. A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science 319, 1391-1394 (2008).
    • (2008) Science , vol.319 , pp. 1391-1394
    • Liu, C.I.1
  • 10
    • 0025800392 scopus 로고
    • Assay of metabolic superoxide production in Escherichia coli
    • Imlay, J.A. & Fridovich, I. Assay of metabolic superoxide production in Escherichia coli. J. Biol. Chem. 266, 6957-6965 (1991).
    • (1991) J. Biol. Chem , vol.266 , pp. 6957-6965
    • Imlay, J.A.1    Fridovich, I.2
  • 11
    • 77949342990 scopus 로고    scopus 로고
    • Two sources of endogenous hydrogen peroxide in Escherichia coli
    • Korshunov, S. & Imlay, J.A. Two sources of endogenous hydrogen peroxide in Escherichia coli. Mol. Microbiol. 75, 1389-1401 (2010).
    • (2010) Mol. Microbiol , vol.75 , pp. 1389-1401
    • Korshunov, S.1    Imlay, J.A.2
  • 12
    • 0028108347 scopus 로고
    • Activation of molecular oxygen by flavins and flavoproteins
    • Massey, V. Activation of molecular oxygen by flavins and flavoproteins. J. Biol. Chem. 269, 22459-22462 (1994).
    • (1994) J. Biol. Chem , vol.269 , pp. 22459-22462
    • Massey, V.1
  • 13
    • 0033538048 scopus 로고    scopus 로고
    • The identification of primary sites of superoxide and hydrogen peroxide formation in the aerobic respiratory chain and sulfite reductase complex of Escherichia coli
    • Messner, K.R. & Imlay, J.A. The identification of primary sites of superoxide and hydrogen peroxide formation in the aerobic respiratory chain and sulfite reductase complex of Escherichia coli. J. Biol. Chem. 274, 10119-10128 (1999).
    • (1999) J. Biol. Chem , vol.274 , pp. 10119-10128
    • Messner, K.R.1    Imlay, J.A.2
  • 14
    • 45149111660 scopus 로고    scopus 로고
    • The growing scope of applications of genome-scale metabolic reconstructions using Escherichia coli
    • Feist, A.M. & Palsson, B.O. The growing scope of applications of genome-scale metabolic reconstructions using Escherichia coli. Nat. Biotechnol. 26, 659-667 (2008).
    • (2008) Nat. Biotechnol , vol.26 , pp. 659-667
    • Feist, A.M.1    Palsson, B.O.2
  • 15
    • 44949225040 scopus 로고    scopus 로고
    • Context-specific metabolic networks are consistent with experiments
    • Becker, S.A. & Palsson, B.O. Context-specific metabolic networks are consistent with experiments. PLoS Comput. Biol. 4, e1000082 (2008).
    • (2008) PLoS Comput. Biol , vol.4
    • Becker, S.A.1    Palsson, B.O.2
  • 16
    • 2342648924 scopus 로고    scopus 로고
    • Integrating high-throughput and computational data elucidates bacterial networks
    • Covert, M.W., Knight, E.M., Reed, J.L., Herrgard, M.J. & Palsson, B.O. Integrating high-throughput and computational data elucidates bacterial networks. Nature 429, 92-96 (2004).
    • (2004) Nature , vol.429 , pp. 92-96
    • Covert, M.W.1    Knight, E.M.2    Reed, J.L.3    Herrgard, M.J.4    Palsson, B.O.5
  • 17
    • 34347332311 scopus 로고    scopus 로고
    • A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information
    • Feist, A.M. et al. A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information. Mol. Syst. Biol. 3, 121 (2007).
    • (2007) Mol. Syst. Biol , vol.3 , pp. 121
    • Feist, A.M.1
  • 18
    • 0037044847 scopus 로고    scopus 로고
    • Mechanism of superoxide and hydrogen peroxide formation by fumarate reductase, succinate dehydrogenase, and aspartate oxidase
    • Messner, K.R. & Imlay, J.A. Mechanism of superoxide and hydrogen peroxide formation by fumarate reductase, succinate dehydrogenase, and aspartate oxidase. J. Biol. Chem. 277, 42563-42571 (2002).
    • (2002) J. Biol. Chem , vol.277 , pp. 42563-42571
    • Messner, K.R.1    Imlay, J.A.2
  • 19
    • 0035125986 scopus 로고    scopus 로고
    • In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data
    • Edwards, J.S., Ibarra, R.U. & Palsson, B.O. In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data. Nat. Biotechnol. 19, 125-130 (2001).
    • (2001) Nat. Biotechnol , vol.19 , pp. 125-130
    • Edwards, J.S.1    Ibarra, R.U.2    Palsson, B.O.3
  • 20
    • 0242608621 scopus 로고    scopus 로고
    • Pathways of oxidative damage
    • Imlay, J.A. Pathways of oxidative damage. Annu. Rev. Microbiol. 57, 395-418 (2003).
    • (2003) Annu. Rev. Microbiol , vol.57 , pp. 395-418
    • Imlay, J.A.1
  • 21
    • 55449092300 scopus 로고    scopus 로고
    • Bleach activates a redox-regulated chaperone by oxidative protein unfolding
    • Winter, J., Ilbert, M., Graf, P.C., Ozcelik, D. & Jakob, U. Bleach activates a redox-regulated chaperone by oxidative protein unfolding. Cell 135, 691-701 (2008).
    • (2008) Cell , vol.135 , pp. 691-701
    • Winter, J.1    Ilbert, M.2    Graf, P.C.3    Ozcelik, D.4    Jakob, U.5
  • 23
    • 0026485287 scopus 로고
    • Carbon and energy metabolism of atp mutants of Escherichia coli
    • Jensen, P.R. & Michelsen, O. Carbon and energy metabolism of atp mutants of Escherichia coli. J. Bacteriol. 174, 7635-7641 (1992).
    • (1992) J. Bacteriol , vol.174 , pp. 7635-7641
    • Jensen, P.R.1    Michelsen, O.2
  • 24
    • 4544312369 scopus 로고    scopus 로고
    • The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: Novel insights into drug mechanisms of action
    • Boshoff, H.I. et al. The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action. J. Biol. Chem. 279, 40174-40184 (2004).
    • (2004) J. Biol. Chem , vol.279 , pp. 40174-40184
    • Boshoff, H.I.1
  • 25
    • 70449449392 scopus 로고    scopus 로고
    • Genome scale reconstruction of a Salmonella metabolic model: Comparison of similarity and differences with a commensal Escherichia coli strain
    • AbuOun, M. et al. Genome scale reconstruction of a Salmonella metabolic model: comparison of similarity and differences with a commensal Escherichia coli strain. J. Biol. Chem. 284, 29480-29488 (2009).
    • (2009) J. Biol. Chem , vol.284 , pp. 29480-29488
    • Abuoun, M.1
  • 26
    • 17844405878 scopus 로고    scopus 로고
    • Genome-scale reconstruction of the metabolic network in Staphylococcus aureus N315: An initial draft to the two-dimensional annotation
    • Becker, S.A. & Palsson, B.O. Genome-scale reconstruction of the metabolic network in Staphylococcus aureus N315: an initial draft to the two-dimensional annotation. BMC Microbiol. 5, 8 (2005).
    • (2005) BMC Microbiol , vol.5 , pp. 8
    • Becker, S.A.1    Palsson, B.O.2
  • 27
    • 34447317247 scopus 로고    scopus 로고
    • Investigating the metabolic capabilities of Mycobacterium tuberculosis H37Rv using the in silico strain iNJ661 and proposing alternative drug targets
    • Jamshidi, N. & Palsson, B.O. Investigating the metabolic capabilities of Mycobacterium tuberculosis H37Rv using the in silico strain iNJ661 and proposing alternative drug targets. BMC Syst. Biol. 1, 26 (2007).
    • (2007) BMC Syst. Biol , vol.1 , pp. 26
    • Jamshidi, N.1    Palsson, B.O.2
  • 28
    • 0034615788 scopus 로고    scopus 로고
    • Assessment of the metabolic capabilities of Haemophilus influenzae Rd through a genome-scale pathway analysis
    • Schilling, C.H. & Palsson, B.O. Assessment of the metabolic capabilities of Haemophilus influenzae Rd through a genome-scale pathway analysis. J. Theor. Biol. 203, 249-283 (2000).
    • (2000) J. Theor. Biol , vol.203 , pp. 249-283
    • Schilling, C.H.1    Palsson, B.O.2
  • 29
    • 77956696072 scopus 로고    scopus 로고
    • High-throughput generation, optimization and analysis of genome-scale metabolic models
    • Henry, C.S. et al. High-throughput generation, optimization and analysis of genome-scale metabolic models. Nat. Biotechnol. 28, 977-982 (2010).
    • (2010) Nat. Biotechnol , vol.28 , pp. 977-982
    • Henry, C.S.1
  • 30
    • 31544450286 scopus 로고    scopus 로고
    • Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: The Keio collection
    • 2006.0008
    • Baba, T. et al. Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2, 2006.0008 (2006).
    • (2006) Mol. Syst. Biol , vol.2
    • Baba, T.1
  • 31
    • 33645283923 scopus 로고    scopus 로고
    • Genetically encoded fluorescent indicator for intracellular hydrogen peroxide
    • Belousov, V.V. et al. Genetically encoded fluorescent indicator for intracellular hydrogen peroxide. Nat. Methods 3, 281-286 (2006).
    • (2006) Nat. Methods , vol.3 , pp. 281-286
    • Belousov, V.V.1
  • 33
    • 0029858146 scopus 로고    scopus 로고
    • Hypochlorous acid stress in Escherichia coli: Resistance DNA damage and comparison with hydrogen peroxide stress
    • Dukan, S. & Touati, D. Hypochlorous acid stress in Escherichia coli: resistance, DNA damage, and comparison with hydrogen peroxide stress. J. Bacteriol. 178, 6145-6150 (1996).
    • (1996) J. Bacteriol , vol.178 , pp. 6145-6150
    • Dukan, S.1    Touati, D.2
  • 34
    • 33847611532 scopus 로고    scopus 로고
    • Networks from drug-drug surfaces
    • Yeh, P. & Kishony, R. Networks from drug-drug surfaces. Mol. Syst. Biol. 3, 85 (2007).
    • (2007) Mol. Syst. Biol , vol.3 , pp. 85
    • Yeh, P.1    Kishony, R.2
  • 36
    • 34347258175 scopus 로고    scopus 로고
    • Quantitative prediction of cellular metabolism with constraint-based models: The COBRA Toolbox
    • Becker, S.A. et al. Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox. Nat. Protoc. 2, 727-738 (2007).
    • (2007) Nat. Protoc , vol.2 , pp. 727-738
    • Becker, S.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.