Mycobacterium tuberculosis WhiB3 Maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response

PLoS Pathogens

Volumn 5, Issue 8, 2009, Pages

  Singh, Amit ^a   Crossman, David K ^a   Mai, Deborah ^a   Guidry, Loni ^a   Voskuil, Martin I ^b   Renfrow, Matthew B ^c   Steyn, Adrie J C ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BACTERIAL PROTEIN WHIB3; CYTOKINE; FATTY ACID; POLYKETIDE; PROPIONIC ACID; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN; LIPID; PROPIONIC ACID DERIVATIVE;

ANIMAL CELL; ARTICLE; BACTERIAL VIRULENCE; CELL SHAPE; CELL SIZE; CONTROLLED STUDY; DNA BINDING; INNATE IMMUNITY; ISOTOPE LABELING; LIPID COMPOSITION; LIPOGENESIS; MACROPHAGE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PROMOTER REGION; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; BIOSYNTHESIS; CELL LINE; CELL WALL; CHEMISTRY; HOMEOSTASIS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; LIPID METABOLISM; METABOLISM; MOUSE; PATHOGENICITY; PHYSIOLOGY; TUBERCULOSIS; VIRULENCE;

MYCOBACTERIUM TUBERCULOSIS;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELL LINE; CELL WALL; HOMEOSTASIS; HOST-PATHOGEN INTERACTIONS; LIPID METABOLISM; LIPIDS; MACROPHAGES; MICE; MYCOBACTERIUM TUBERCULOSIS; OXIDATION-REDUCTION; PROPIONATES; TUBERCULOSIS; VIRULENCE;

EID: 70149116303     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000545     Document Type: Article

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