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Volumn 85, Issue 6, 2012, Pages 1148-1165

Mycobacterium tuberculosis WhiB4 regulates oxidative stress response to modulate survival and dissemination in vivo

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL HYDROPEROXIDASE; ANTIOXIDANT; DNA BINDING PROTEIN; NITRIC OXIDE; OXYGEN; RUBREDOXIN; UNCLASSIFIED DRUG; WHIB4 PROTEIN;

EID: 84866029444     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2012.08165.x     Document Type: Article
Times cited : (79)

References (59)
  • 1
    • 33846942978 scopus 로고    scopus 로고
    • Molecular function of WhiB4/Rv3681c of Mycobacterium tuberculosis H37Rv: a [4Fe-4S] cluster co-ordinating protein disulphide reductase
    • Alam, M.S., Garg, S.K., and Agrawal, P. (2007) Molecular function of WhiB4/Rv3681c of Mycobacterium tuberculosis H37Rv: a [4Fe-4S] cluster co-ordinating protein disulphide reductase. Mol Microbiol 63: 1414-1431.
    • (2007) Mol Microbiol , vol.63 , pp. 1414-1431
    • Alam, M.S.1    Garg, S.K.2    Agrawal, P.3
  • 2
    • 57649186810 scopus 로고    scopus 로고
    • Studies on structural and functional divergence among seven WhiB proteins of Mycobacterium tuberculosis H37Rv
    • Alam, M.S., Garg, S.K., and Agrawal, P. (2009) Studies on structural and functional divergence among seven WhiB proteins of Mycobacterium tuberculosis H37Rv. FEBS J 276: 76-93.
    • (2009) FEBS J , vol.276 , pp. 76-93
    • Alam, M.S.1    Garg, S.K.2    Agrawal, P.3
  • 3
    • 0036774617 scopus 로고    scopus 로고
    • Specialized transduction: an efficient method for generating marked and unmarked targeted gene disruptions in Mycobacterium tuberculosis, M. bovis BCG and M. smegmatis
    • Bardarov, S., Bardarov, S., Jr, Pavelka, M.S., Jr, Sambandamurthy, V., Larsen, M., Tufariello, J., etal. (2002) Specialized transduction: an efficient method for generating marked and unmarked targeted gene disruptions in Mycobacterium tuberculosis, M. bovis BCG and M. smegmatis. Microbiology 148: 3007-3017.
    • (2002) Microbiology , vol.148 , pp. 3007-3017
    • Bardarov, S.1    Bardarov Jr., S.2    Pavelka Jr., M.S.3    Sambandamurthy, V.4    Larsen, M.5    Tufariello, J.6
  • 4
    • 0036270739 scopus 로고    scopus 로고
    • Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling
    • Betts, J.C., Lukey, P.T., Robb, L.C., McAdam, R.A., and Duncan, K. (2002) Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling. Mol Microbiol 43: 717-731.
    • (2002) Mol Microbiol , vol.43 , pp. 717-731
    • Betts, J.C.1    Lukey, P.T.2    Robb, L.C.3    McAdam, R.A.4    Duncan, K.5
  • 5
    • 0041922652 scopus 로고    scopus 로고
    • Signature gene expression profiles discriminate between isoniazid-, thiolactomycin-, and triclosan-treated Mycobacterium tuberculosis
    • Betts, J.C., McLaren, A., Lennon, M.G., Kelly, F.M., Lukey, P.T., Blakemore, S.J., and Duncan, K. (2003) Signature gene expression profiles discriminate between isoniazid-, thiolactomycin-, and triclosan-treated Mycobacterium tuberculosis. Antimicrob Agents Chemother 47: 2903-2913.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 2903-2913
    • Betts, J.C.1    McLaren, A.2    Lennon, M.G.3    Kelly, F.M.4    Lukey, P.T.5    Blakemore, S.J.6    Duncan, K.7
  • 6
    • 0031830815 scopus 로고    scopus 로고
    • Minor groove-binding architectural proteins: structure, function, and DNA recognition
    • Bewley, C.A., Gronenborn, A.M., and Clore, G.M. (1998) Minor groove-binding architectural proteins: structure, function, and DNA recognition. Annu Rev Biophys Biomol Struct 27: 105-131.
    • (1998) Annu Rev Biophys Biomol Struct , vol.27 , pp. 105-131
    • Bewley, C.A.1    Gronenborn, A.M.2    Clore, G.M.3
  • 7
    • 0036078710 scopus 로고    scopus 로고
    • Dissemination of Mycobacterium tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity
    • Chackerian, A.A., Alt, J.M., Perera, T.V., Dascher, C.C., and Behar, S.M. (2002) Dissemination of Mycobacterium tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity. Infect Immun 70: 4501-4509.
    • (2002) Infect Immun , vol.70 , pp. 4501-4509
    • Chackerian, A.A.1    Alt, J.M.2    Perera, T.V.3    Dascher, C.C.4    Behar, S.M.5
  • 8
    • 0032060482 scopus 로고    scopus 로고
    • Alkyl hydroperoxide reductase subunit C (AhpC) protects bacterial and human cells against reactive nitrogen intermediates
    • Chen, L., Xie, Q.W., and Nathan, C. (1998) Alkyl hydroperoxide reductase subunit C (AhpC) protects bacterial and human cells against reactive nitrogen intermediates. Mol Cell 1: 795-805.
    • (1998) Mol Cell , vol.1 , pp. 795-805
    • Chen, L.1    Xie, Q.W.2    Nathan, C.3
  • 9
    • 70449519188 scopus 로고    scopus 로고
    • Purification of RNA polymerase from mycobacteria for optimized promoter-polymerase interactions
    • China, A., and Nagaraja, V. (2010) Purification of RNA polymerase from mycobacteria for optimized promoter-polymerase interactions. Protein Expr Purif 69: 235-242.
    • (2010) Protein Expr Purif , vol.69 , pp. 235-242
    • China, A.1    Nagaraja, V.2
  • 10
    • 34347333558 scopus 로고    scopus 로고
    • Transcriptional regulation of multi-drug tolerance and antibiotic-induced responses by the histone-like protein Lsr2 in M. tuberculosis
    • Colangeli, R., Helb, D., Vilcheze, C., Hazbon, M.H., Lee, C.G., Safi, H., etal. (2007) Transcriptional regulation of multi-drug tolerance and antibiotic-induced responses by the histone-like protein Lsr2 in M. tuberculosis. PLoS Pathog 3: e87.
    • (2007) PLoS Pathog , vol.3
    • Colangeli, R.1    Helb, D.2    Vilcheze, C.3    Hazbon, M.H.4    Lee, C.G.5    Safi, H.6
  • 12
    • 0035476428 scopus 로고    scopus 로고
    • A role for rubredoxin in oxidative stress protection in Desulfovibrio vulgaris: catalytic electron transfer to rubrerythrin and two-iron superoxide reductase
    • Coulter, E.D., and Kurtz, D.M., Jr (2001) A role for rubredoxin in oxidative stress protection in Desulfovibrio vulgaris: catalytic electron transfer to rubrerythrin and two-iron superoxide reductase. Arch Biochem Biophys 394: 76-86.
    • (2001) Arch Biochem Biophys , vol.394 , pp. 76-86
    • Coulter, E.D.1    Kurtz Jr., D.M.2
  • 13
    • 1542364538 scopus 로고    scopus 로고
    • Mechanism of oxygen sensing by the bacterial transcription factor fumarate-nitrate reduction (FNR)
    • Crack, J., Green, J., and Thomson, A.J. (2004) Mechanism of oxygen sensing by the bacterial transcription factor fumarate-nitrate reduction (FNR). J Biol Chem 279: 9278-9286.
    • (2004) J Biol Chem , vol.279 , pp. 9278-9286
    • Crack, J.1    Green, J.2    Thomson, A.J.3
  • 14
    • 0036646484 scopus 로고    scopus 로고
    • NO sensing by FNR: regulation of the Escherichia coli NO-detoxifying flavohaemoglobin, Hmp
    • Cruz-Ramos, H., Crack, J., Wu, G., Hughes, M.N., Scott, C., Thomson, A.J., etal. (2002) NO sensing by FNR: regulation of the Escherichia coli NO-detoxifying flavohaemoglobin, Hmp. EMBO J 21: 3235-3244.
    • (2002) EMBO J , vol.21 , pp. 3235-3244
    • Cruz-Ramos, H.1    Crack, J.2    Wu, G.3    Hughes, M.N.4    Scott, C.5    Thomson, A.J.6
  • 15
    • 0028882958 scopus 로고
    • Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative-stress regulatory gene: implications for sensitivity to isoniazid
    • Deretic, V., Philipp, W., Dhandayuthapani, S., Mudd, M.H., Curcic, R., Garbe, T., etal. (1995) Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative-stress regulatory gene: implications for sensitivity to isoniazid. Mol Microbiol 17: 889-900.
    • (1995) Mol Microbiol , vol.17 , pp. 889-900
    • Deretic, V.1    Philipp, W.2    Dhandayuthapani, S.3    Mudd, M.H.4    Curcic, R.5    Garbe, T.6
  • 16
    • 76949089832 scopus 로고    scopus 로고
    • Bacterial nucleoid-associated proteins, nucleoid structure and gene expression
    • Dillon, S.C., and Dorman, C.J. (2010) Bacterial nucleoid-associated proteins, nucleoid structure and gene expression. Nat Rev Microbiol 8: 185-195.
    • (2010) Nat Rev Microbiol , vol.8 , pp. 185-195
    • Dillon, S.C.1    Dorman, C.J.2
  • 17
    • 44949094526 scopus 로고    scopus 로고
    • ApoFnr binds as a monomer to promoters regulating the expression of enterotoxin genes of Bacillus cereus
    • Esbelin, J., Jouanneau, Y., Armengaud, J., and Duport, C. (2008) ApoFnr binds as a monomer to promoters regulating the expression of enterotoxin genes of Bacillus cereus. J Bacteriol 190: 4242-4251.
    • (2008) J Bacteriol , vol.190 , pp. 4242-4251
    • Esbelin, J.1    Jouanneau, Y.2    Armengaud, J.3    Duport, C.4
  • 18
    • 78349251639 scopus 로고    scopus 로고
    • Reductive stress in microbes: implications for understanding Mycobacterium tuberculosis disease and persistence
    • Farhana, A., Guidry, L., Srivastava, A., Singh, A., Hondalus, M.K., and Steyn, A.J. (2010) Reductive stress in microbes: implications for understanding Mycobacterium tuberculosis disease and persistence. Adv Microb Physiol 57: 43-117.
    • (2010) Adv Microb Physiol , vol.57 , pp. 43-117
    • Farhana, A.1    Guidry, L.2    Srivastava, A.3    Singh, A.4    Hondalus, M.K.5    Steyn, A.J.6
  • 19
    • 0036299641 scopus 로고    scopus 로고
    • Microarray analysis of the Mycobacterium tuberculosis transcriptional response to the acidic conditions found in phagosomes
    • Fisher, M.A., Plikaytis, B.B., and Shinnick, T.M. (2002) Microarray analysis of the Mycobacterium tuberculosis transcriptional response to the acidic conditions found in phagosomes. J Bacteriol 184: 4025-4032.
    • (2002) J Bacteriol , vol.184 , pp. 4025-4032
    • Fisher, M.A.1    Plikaytis, B.B.2    Shinnick, T.M.3
  • 20
    • 33746904362 scopus 로고    scopus 로고
    • Differential gene expression in response to exposure to antimycobacterial agents and other stress conditions among seven Mycobacterium tuberculosis whiB-like genes
    • Geiman, D.E., Raghunand, T.R., Agarwal, N., and Bishai, W.R. (2006) Differential gene expression in response to exposure to antimycobacterial agents and other stress conditions among seven Mycobacterium tuberculosis whiB-like genes. Antimicrob Agents Chemother 50: 2836-2841.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 2836-2841
    • Geiman, D.E.1    Raghunand, T.R.2    Agarwal, N.3    Bishai, W.R.4
  • 21
    • 0029917091 scopus 로고    scopus 로고
    • The rRNA operons of Mycobacterium smegmatis and Mycobacterium tuberculosis: comparison of promoter elements and of neighbouring upstream genes
    • Gonzalez-y-Merchand, J.A., Colston, M.J., and Cox, R.A. (1996) The rRNA operons of Mycobacterium smegmatis and Mycobacterium tuberculosis: comparison of promoter elements and of neighbouring upstream genes. Microbiology 142: 667-674.
    • (1996) Microbiology , vol.142 , pp. 667-674
    • Gonzalez-y-Merchand, J.A.1    Colston, M.J.2    Cox, R.A.3
  • 22
    • 79960606195 scopus 로고    scopus 로고
    • Structural basis for recognition of AT-rich DNA by unrelated xenogeneic silencing proteins
    • Gordon, B.R., Li, Y., Cote, A., Weirauch, M.T., Ding, P., Hughes, T.R., etal. (2011) Structural basis for recognition of AT-rich DNA by unrelated xenogeneic silencing proteins. Proc Natl Acad Sci USA 108: 10690-10695.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 10690-10695
    • Gordon, B.R.1    Li, Y.2    Cote, A.3    Weirauch, M.T.4    Ding, P.5    Hughes, T.R.6
  • 23
    • 0036244434 scopus 로고    scopus 로고
    • Macrophage defences against respiratory tract infections
    • Gordon, S.B., and Read, R.C. (2002) Macrophage defences against respiratory tract infections. Br Med Bull 61: 45-61.
    • (2002) Br Med Bull , vol.61 , pp. 45-61
    • Gordon, S.B.1    Read, R.C.2
  • 24
    • 9444239308 scopus 로고    scopus 로고
    • Bacterial redox sensors
    • Green, J., and Paget, M.S. (2004) Bacterial redox sensors. Nat Rev Microbiol 2: 954-966.
    • (2004) Nat Rev Microbiol , vol.2 , pp. 954-966
    • Green, J.1    Paget, M.S.2
  • 25
    • 67650082448 scopus 로고    scopus 로고
    • Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system
    • Guo, M., Feng, H., Zhang, J., Wang, W., Wang, Y., Li, Y., etal. (2009) Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res 19: 1301-1308.
    • (2009) Genome Res , vol.19 , pp. 1301-1308
    • Guo, M.1    Feng, H.2    Zhang, J.3    Wang, W.4    Wang, Y.5    Li, Y.6
  • 26
    • 78651081719 scopus 로고    scopus 로고
    • Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners
    • Haft, D.H. (2011) Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners. BMC Genomics 12: 21.
    • (2011) BMC Genomics , vol.12 , pp. 21
    • Haft, D.H.1
  • 28
    • 14844290234 scopus 로고    scopus 로고
    • Evidence that the Streptomyces developmental protein WhiD, a member of the WhiB family, binds a [4Fe-4S] cluster
    • Jakimowicz, P., Cheesman, M.R., Bishai, W.R., Chater, K.F., Thomson, A.J., and Buttner, M.J. (2005) Evidence that the Streptomyces developmental protein WhiD, a member of the WhiB family, binds a [4Fe-4S] cluster. J Biol Chem 280: 8309-8315.
    • (2005) J Biol Chem , vol.280 , pp. 8309-8315
    • Jakimowicz, P.1    Cheesman, M.R.2    Bishai, W.R.3    Chater, K.F.4    Thomson, A.J.5    Buttner, M.J.6
  • 30
    • 0344081940 scopus 로고    scopus 로고
    • Artificial neural networks for prediction of mycobacterial promoter sequences
    • Kalate, R.N., Tambe, S.S., and Kulkarni, B.D. (2003) Artificial neural networks for prediction of mycobacterial promoter sequences. Comput Biol Chem 27: 555-564.
    • (2003) Comput Biol Chem , vol.27 , pp. 555-564
    • Kalate, R.N.1    Tambe, S.S.2    Kulkarni, B.D.3
  • 31
    • 38349088326 scopus 로고    scopus 로고
    • Altered expression of isoniazid-regulated genes in drug-treated dormant Mycobacterium tuberculosis
    • Karakousis, P.C., Williams, E.P., and Bishai, W.R. (2008) Altered expression of isoniazid-regulated genes in drug-treated dormant Mycobacterium tuberculosis. J Antimicrob Chemother 61: 323-331.
    • (2008) J Antimicrob Chemother , vol.61 , pp. 323-331
    • Karakousis, P.C.1    Williams, E.P.2    Bishai, W.R.3
  • 33
    • 57749196742 scopus 로고    scopus 로고
    • Differentially expressed genes in Mycobacterium tuberculosis H37Rv under mild acidic and hypoxic conditions
    • Kim, S.Y., Lee, B.S., Shin, S.J., Kim, H.J., and Park, J.K. (2008) Differentially expressed genes in Mycobacterium tuberculosis H37Rv under mild acidic and hypoxic conditions. J Med Microbiol 57: 1473-1480.
    • (2008) J Med Microbiol , vol.57 , pp. 1473-1480
    • Kim, S.Y.1    Lee, B.S.2    Shin, S.J.3    Kim, H.J.4    Park, J.K.5
  • 34
    • 77649112187 scopus 로고    scopus 로고
    • Genome-wide analysis of the host intracellular network that regulates survival of Mycobacterium tuberculosis
    • Kumar, D., Nath, L., Kamal, M.A., Varshney, A., Jain, A., Singh, S., and Rao, K.V. (2010) Genome-wide analysis of the host intracellular network that regulates survival of Mycobacterium tuberculosis. Cell 140: 731-743.
    • (2010) Cell , vol.140 , pp. 731-743
    • Kumar, D.1    Nath, L.2    Kamal, M.A.3    Varshney, A.4    Jain, A.5    Singh, S.6    Rao, K.V.7
  • 35
    • 44949109341 scopus 로고    scopus 로고
    • Susceptibility to mycobacterial infections in children with X-linked chronic granulomatous disease: a review of 17 patients living in a region endemic for tuberculosis
    • Lee, P.P., Chan, K.W., Jiang, L., Chen, T., Li, C., Lee, T.L., etal. (2008) Susceptibility to mycobacterial infections in children with X-linked chronic granulomatous disease: a review of 17 patients living in a region endemic for tuberculosis. Pediatr Infect Dis J 27: 224-230.
    • (2008) Pediatr Infect Dis J , vol.27 , pp. 224-230
    • Lee, P.P.1    Chan, K.W.2    Jiang, L.3    Chen, T.4    Li, C.5    Lee, T.L.6
  • 37
    • 0037076333 scopus 로고    scopus 로고
    • Repression of photosynthesis gene expression by formation of a disulfide bond in CrtJ
    • Masuda, S., Dong, C., Swem, D., Setterdahl, A.T., Knaff, D.B., and Bauer, C.E. (2002) Repression of photosynthesis gene expression by formation of a disulfide bond in CrtJ. Proc Natl Acad Sci USA 99: 7078-7083.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 7078-7083
    • Masuda, S.1    Dong, C.2    Swem, D.3    Setterdahl, A.T.4    Knaff, D.B.5    Bauer, C.E.6
  • 39
    • 0026569136 scopus 로고
    • Reduced intracellular growth of mycobacteria in human macrophages cultivated at physiologic oxygen pressure
    • Meylan, P.R., Richman, D.D., and Kornbluth, R.S. (1992b) Reduced intracellular growth of mycobacteria in human macrophages cultivated at physiologic oxygen pressure. Am Rev Respir Dis 145: 947-953.
    • (1992) Am Rev Respir Dis , vol.145 , pp. 947-953
    • Meylan, P.R.1    Richman, D.D.2    Kornbluth, R.S.3
  • 41
    • 61349134073 scopus 로고    scopus 로고
    • Sequence-specific binding to a subset of IscR-regulated promoters does not require IscR Fe-S cluster ligation
    • Nesbit, A.D., Giel, J.L., Rose, J.C., and Kiley, P.J. (2009) Sequence-specific binding to a subset of IscR-regulated promoters does not require IscR Fe-S cluster ligation. J Mol Biol 387: 28-41.
    • (2009) J Mol Biol , vol.387 , pp. 28-41
    • Nesbit, A.D.1    Giel, J.L.2    Rose, J.C.3    Kiley, P.J.4
  • 42
    • 2942538880 scopus 로고    scopus 로고
    • Role of KatG catalase-peroxidase in mycobacterial pathogenesis: countering the phagocyte oxidative burst
    • Ng, V.H., Cox, J.S., Sousa, A.O., MacMicking, J.D., and McKinney, J.D. (2004) Role of KatG catalase-peroxidase in mycobacterial pathogenesis: countering the phagocyte oxidative burst. Mol Microbiol 52: 1291-1302.
    • (2004) Mol Microbiol , vol.52 , pp. 1291-1302
    • Ng, V.H.1    Cox, J.S.2    Sousa, A.O.3    MacMicking, J.D.4    McKinney, J.D.5
  • 43
    • 0031660550 scopus 로고    scopus 로고
    • Oxidative stress response and characterization of the oxyR-ahpC and furA-katG loci in Mycobacterium marinum
    • Pagan-Ramos, E., Song, J., McFalone, M., Mudd, M.H., and Deretic, V. (1998) Oxidative stress response and characterization of the oxyR-ahpC and furA-katG loci in Mycobacterium marinum. J Bacteriol 180: 4856-4864.
    • (1998) J Bacteriol , vol.180 , pp. 4856-4864
    • Pagan-Ramos, E.1    Song, J.2    McFalone, M.3    Mudd, M.H.4    Deretic, V.5
  • 44
    • 33646070307 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis gene expression profiling within the context of protein networks
    • Rachman, H., Strong, M., Schaible, U., Schuchhardt, J., Hagens, K., Mollenkopf, H., etal. (2006) Mycobacterium tuberculosis gene expression profiling within the context of protein networks. Microbes Infect 8: 747-757.
    • (2006) Microbes Infect , vol.8 , pp. 747-757
    • Rachman, H.1    Strong, M.2    Schaible, U.3    Schuchhardt, J.4    Hagens, K.5    Mollenkopf, H.6
  • 45
    • 70350686719 scopus 로고    scopus 로고
    • The role of DNA shape in protein-DNA recognition
    • Rohs, R., West, S.M., Sosinsky, A., Liu, P., Mann, R.S., and Honig, B. (2009) The role of DNA shape in protein-DNA recognition. Nature 461: 1248-1253.
    • (2009) Nature , vol.461 , pp. 1248-1253
    • Rohs, R.1    West, S.M.2    Sosinsky, A.3    Liu, P.4    Mann, R.S.5    Honig, B.6
  • 46
    • 43049182981 scopus 로고    scopus 로고
    • The enduring hypoxic response of Mycobacterium tuberculosis
    • Rustad, T.R., Harrell, M.I., Liao, R., and Sherman, D.R. (2008) The enduring hypoxic response of Mycobacterium tuberculosis. PLoS ONE 3: e1502.
    • (2008) PLoS ONE , vol.3
    • Rustad, T.R.1    Harrell, M.I.2    Liao, R.3    Sherman, D.R.4
  • 47
    • 77954835360 scopus 로고    scopus 로고
    • Insights into the function of the WhiB-like protein of mycobacteriophage TM4 - a transcriptional inhibitor of WhiB2
    • Rybniker, J., Nowag, A., van Gumpel, E., Nissen, N., Robinson, N., Plum, G., and Hartmann, P. (2010) Insights into the function of the WhiB-like protein of mycobacteriophage TM4 - a transcriptional inhibitor of WhiB2. Mol Microbiol 77: 642-657.
    • (2010) Mol Microbiol , vol.77 , pp. 642-657
    • Rybniker, J.1    Nowag, A.2    van Gumpel, E.3    Nissen, N.4    Robinson, N.5    Plum, G.6    Hartmann, P.7
  • 48
    • 0031914958 scopus 로고    scopus 로고
    • Cytokine activation leads to acidification and increases maturation of Mycobacterium avium-containing phagosomes in murine macrophages
    • Schaible, U.E., Sturgill-Koszycki, S., Schlesinger, P.H., and Russell, D.G. (1998) Cytokine activation leads to acidification and increases maturation of Mycobacterium avium-containing phagosomes in murine macrophages. J Immunol 160: 1290-1296.
    • (1998) J Immunol , vol.160 , pp. 1290-1296
    • Schaible, U.E.1    Sturgill-Koszycki, S.2    Schlesinger, P.H.3    Russell, D.G.4
  • 49
    • 0043142536 scopus 로고    scopus 로고
    • Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: insights into the phagosomal environment
    • Schnappinger, D., Ehrt, S., Voskuil, M.I., Liu, Y., Mangan, J.A., Monahan, I.M., etal. (2003) Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: insights into the phagosomal environment. J Exp Med 198: 693-704.
    • (2003) J Exp Med , vol.198 , pp. 693-704
    • Schnappinger, D.1    Ehrt, S.2    Voskuil, M.I.3    Liu, Y.4    Mangan, J.A.5    Monahan, I.M.6
  • 50
    • 34547463011 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis WhiB3 responds to O2 and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival
    • Singh, A., Guidry, L., Narasimhulu, K.V., Mai, D., Trombley, J., Redding, K.E., etal. (2007) Mycobacterium tuberculosis WhiB3 responds to O2 and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival. Proc Natl Acad Sci USA 104: 11562-11567.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 11562-11567
    • Singh, A.1    Guidry, L.2    Narasimhulu, K.V.3    Mai, D.4    Trombley, J.5    Redding, K.E.6
  • 51
    • 70149116303 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis WhiB3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response
    • Singh, A., Crossman, D.K., Mai, D., Guidry, L., Voskuil, M.I., Renfrow, M.B., and Steyn, A.J. (2009) Mycobacterium tuberculosis WhiB3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response. PLoS Pathog 5: e1000545.
    • (2009) PLoS Pathog , vol.5
    • Singh, A.1    Crossman, D.K.2    Mai, D.3    Guidry, L.4    Voskuil, M.I.5    Renfrow, M.B.6    Steyn, A.J.7
  • 52
    • 10744227858 scopus 로고    scopus 로고
    • Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs
    • Singh, R., Rao, V., Shakila, H., Gupta, R., Khera, A., Dhar, N., etal. (2003) Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs. Mol Microbiol 50: 751-762.
    • (2003) Mol Microbiol , vol.50 , pp. 751-762
    • Singh, R.1    Rao, V.2    Shakila, H.3    Gupta, R.4    Khera, A.5    Dhar, N.6
  • 53
    • 78649856315 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis WhiB1 is an essential DNA-binding protein with a nitric oxide-sensitive iron-sulfur cluster
    • Smith, L.J., Stapleton, M.R., Fullstone, G.J., Crack, J.C., Thomson, A.J., Le Brun, N.E., etal. (2010) Mycobacterium tuberculosis WhiB1 is an essential DNA-binding protein with a nitric oxide-sensitive iron-sulfur cluster. Biochem J 432: 417-427.
    • (2010) Biochem J , vol.432 , pp. 417-427
    • Smith, L.J.1    Stapleton, M.R.2    Fullstone, G.J.3    Crack, J.C.4    Thomson, A.J.5    Le Brun, N.E.6
  • 54
    • 0037022605 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis WhiB3 interacts with RpoV to affect host survival but is dispensable for in vivo growth
    • Steyn, A.J.C., Collins, D.M., Hondalus, M.K., Jacobs, W.R., Jr, Kawakami, R.P., and Bloom, B.R. (2002) Mycobacterium tuberculosis WhiB3 interacts with RpoV to affect host survival but is dispensable for in vivo growth. Proc Natl Acad Sci USA 99: 3147-3152.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 3147-3152
    • Steyn, A.J.C.1    Collins, D.M.2    Hondalus, M.K.3    Jacobs Jr., W.R.4    Kawakami, R.P.5    Bloom, B.R.6
  • 55
    • 0141848318 scopus 로고    scopus 로고
    • Signal transduction by the global regulator RegB is mediated by a redox-active cysteine
    • Swem, L.R., Kraft, B.J., Swem, D.L., Setterdahl, A.T., Masuda, S., Knaff, D.B., etal. (2003) Signal transduction by the global regulator RegB is mediated by a redox-active cysteine. EMBO J 22: 4699-4708.
    • (2003) EMBO J , vol.22 , pp. 4699-4708
    • Swem, L.R.1    Kraft, B.J.2    Swem, D.L.3    Setterdahl, A.T.4    Masuda, S.5    Knaff, D.B.6
  • 56
    • 0026704947 scopus 로고
    • Cloning, sequencing, and overexpression of a [2Fe-2S] ferredoxin gene from Escherichia coli
    • Ta, D.T., and Vickery, L.E. (1992) Cloning, sequencing, and overexpression of a [2Fe-2S] ferredoxin gene from Escherichia coli. J Biol Chem 267: 11120-11125.
    • (1992) J Biol Chem , vol.267 , pp. 11120-11125
    • Ta, D.T.1    Vickery, L.E.2
  • 57
    • 33750699963 scopus 로고    scopus 로고
    • Mechanisms of action of isoniazid
    • Timmins, G.S., and Deretic, V. (2006) Mechanisms of action of isoniazid. Mol Microbiol 62: 1220-1227.
    • (2006) Mol Microbiol , vol.62 , pp. 1220-1227
    • Timmins, G.S.1    Deretic, V.2
  • 58
    • 0027986926 scopus 로고
    • Functional analysis of transcription of the Mycobacterium tuberculosis 16S rDNA-encoding gene
    • Verma, A., Kinger, A.K., and Tyagi, J.S. (1994) Functional analysis of transcription of the Mycobacterium tuberculosis 16S rDNA-encoding gene. Gene 148: 113-118.
    • (1994) Gene , vol.148 , pp. 113-118
    • Verma, A.1    Kinger, A.K.2    Tyagi, J.S.3
  • 59
    • 0030023148 scopus 로고    scopus 로고
    • Rapid PCR method for site-directed mutagenesis on double-stranded plasmid DNA
    • Xu, X., Kang, S.H., Heidenreich, O., Li, Q., and Nerenberg, M. (1996) Rapid PCR method for site-directed mutagenesis on double-stranded plasmid DNA. Biotechniques 20: 44-47.
    • (1996) Biotechniques , vol.20 , pp. 44-47
    • Xu, X.1    Kang, S.H.2    Heidenreich, O.3    Li, Q.4    Nerenberg, M.5


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