Bacillithiol is an antioxidant thiol produced in Bacilli

Nature Chemical Biology

Volumn 5, Issue 9, 2009, Pages 625-627

  Newton, Gerald L ^a   Rawat, Mamta ^b   La Clair, James J ^a   Jothivasan, Vishnu Karthik ^c   Budiarto, Tanya ^a   Hamilton, Chris J ^c   Claiborne, Al ^d   Helmann, John D ^e   Fahey, Robert C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CALIFORNIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^d WAKE FOREST SCHOOL OF MEDICINE   (United States)

^e Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; BACILLITHIOL; CYSTEINYLGLUCOSAMINE; GLUCOSAMINE DERIVATIVE; GLUTATHIONE; GLYCOSIDE; MALIC ACID; MYCOTHIOL; THIOL; UNCLASSIFIED DRUG;

ARTICLE; BACILLI; BACILLUS; DEINOCOCCUS RADIODURANS; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM POSITIVE BACTERIUM; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; MOLECULAR WEIGHT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

BACILLI (CLASS); BACILLUS (BACTERIUM); DEINOCOCCUS RADIODURANS; POSIBACTERIA; STAPHYLOCOCCUS AUREUS;

ANTIOXIDANTS; CYSTEINE; DEINOCOCCUS; GLUCOSAMINE; GLUTATHIONE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STAPHYLOCOCCUS AUREUS; SULFHYDRYL COMPOUNDS;

EID: 69249210905     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.189     Document Type: Article

References (22)

1. Held, K.D. & Biaglow, J.E. Radiat. Res. 139, 15-23 (1994).
2. Fahey, R.C. & Sundquist, A.R. Adv. Enzymol. 64, 1-53 (1991).
3. Meister, A. in Glutathione: Chemical, Biochemical, and Medical Aspects part A (eds. Dolphin, D., Poulson, R. & Avramovic, O.) 367-474 (Wiley, New York, 1989).
4. Fahey, R.C., Brown, W.C., Adams, W.B. & Worsham, M.B. J. Bacteriol. 133, 1126-1129 (1978).
5. Jothivasan, V.K. & Hamilton, C.J. Nat. Prod. Rep. 25, 1091-1117 (2008).
6. Newton, G.L., Buchmeier, N. & Fahey, R.C. Microbiol. Mol. Biol. Rev. 72, 471-494 (2008).
7. Rawat, M. & Av-Gay, Y. FEMS Microbiol. Rev. 31, 278-292 (2007).
8. Newton, G.L. et al. Eur. J. Biochem. 230, 821-825 (1995).
9. Patel, M.P. & Blanchard, J.S. Biochemistry 38, 11827-11833 (1999).
10. Fahey, R.C. & Newton, G.L. in Functions of Glutathione: Biochemical, Physiological, Toxicological and Clinical Aspects (eds. Larsson, A., Orrenius, S., Holmgren, A. & Mannervik, B.) 251-260 (Raven, New York, 1983).
11. delCardayré, S.B., Stock, K.P., Newton, G.L., Fahey, R.C. & Davies, J.E. J. Biol. Chem. 273, 5744-5751 (1998).
12. delCardayré, S.B. & Davies, J.E. J. Biol. Chem. 273, 5752-5757 (1998).
13. Nicely, N.I. et al. Biochemistry 46, 3234-3245 (2007).
14. Lee, J.W., Soonsanga, S. & Helmann, J.D. Proc. Natl. Acad. Sci. USA 104, 8743-8748 (2007).
15. Soonsanga, S., Lee, J.W. & Helmann, J.D. Mol. Microbiol. 68, 978-986 (2008).
16. Rotzoll, N., Dunkel, A. & Hofmann, T. J. Agric. Food Chem. 53, 4149-4156 (2005).
17. Hermansson, K., Kenne, L., Rukunga, G.M. & Samuelsson, G. Phytochemistry 29, 513-515 (1990).
18. Lithgow, J.K., Hayhurst, E.J., Cohen, G., Aharonowitz, Y. & Foster, S.J. J. Bacteriol. 186, 1579-1590 (2004).
19. Wallen, J.R., Paige, C., Mallett, T.C., Karplus, P.A. & Claiborne, A. Biochemistry 47, 5182-5193 (2008).
20. Hoch, J.A. & Coukoulis, H.J. J. Bacteriol. 133, 265-269 (1978).
21. Mostertz, J., Hochgrafe, F., Jurgen, B., Schweder, T. & Hecker, M. Proteomics 8, 2676-2690 (2008).
22. Holmgren, A. Annu. Rev. Biochem. 54, 237-271 (1985).