-
1
-
-
4444256472
-
2003 Annual report of the american association of poison control centers toxic exposure surveillance system
-
Watson, W.A., Litovitz, T.L., Klein-Schwartz, W., Rodgers, G.C. Jr., Youniss, J., Reid, N., Rouse, W.G., Rembert, R.S. and Borys, D. (2004) 2003 Annual report of the american association of poison control centers toxic exposure surveillance system. Am. J. Emerg. Med., 22, 335-404.
-
(2004)
Am. J. Emerg. Med.
, vol.22
, pp. 335-404
-
-
Watson, W.A.1
Litovitz, T.L.2
Klein-Schwartz, W.3
Rodgers Jr., G.C.4
Youniss, J.5
Reid, N.6
Rouse, W.G.7
Rembert, R.S.8
Borys, D.9
-
2
-
-
0036274182
-
Paracetamol overdose: an evidence based flowchart to guide management
-
Wallace, C.I., Dargan, P.I. and Jones, A.L. (2002) Paracetamol overdose: an evidence based flowchart to guide management. Emerg. Med. J., 19, 202-205.
-
(2002)
Emerg. Med. J.
, vol.19
, pp. 202-205
-
-
Wallace, C.I.1
Dargan, P.I.2
Jones, A.L.3
-
3
-
-
0021955464
-
Effects of N-acetylcysteine on acetaminophen covalent binding and hepatic necrosis in mice
-
Corcoran, G.B., Racz, W.J., Smith, C.V. and Mitchell, J.R. (1985) Effects of N-acetylcysteine on acetaminophen covalent binding and hepatic necrosis in mice. J. Pharmacol. Exp. Ther., 232, 864-872.
-
(1985)
J. Pharmacol. Exp. Ther.
, vol.232
, pp. 864-872
-
-
Corcoran, G.B.1
Racz, W.J.2
Smith, C.V.3
Mitchell, J.R.4
-
4
-
-
33749169366
-
Comparison of oral and i.v. acetylcysteine in the treatment of acetaminophen poisoning
-
Kanter, M.Z. (2006) Comparison of oral and i.v. acetylcysteine in the treatment of acetaminophen poisoning. Am. J. Health Syst. Pharm., 63, 1821-1827.
-
(2006)
Am. J. Health Syst. Pharm.
, vol.63
, pp. 1821-1827
-
-
Kanter, M.Z.1
-
5
-
-
0024601884
-
Adverse reactions to N-acetylcysteine during treatment for paracetamol poisoning
-
Dawson, A.H., Henry, D.A. and McEwen, J. (1989) Adverse reactions to N-acetylcysteine during treatment for paracetamol poisoning. Med. J. Aust., 150, 329-331.
-
(1989)
Med. J. Aust.
, vol.150
, pp. 329-331
-
-
Dawson, A.H.1
Henry, D.A.2
McEwen, J.3
-
6
-
-
0030236901
-
Paracetamol poisoning: the action line and the timing of acetylcysteine therapy
-
Delanty, N. and Fitzgerald, D.J. (1996) Paracetamol poisoning: the action line and the timing of acetylcysteine therapy. Ir. Med. J., 89, 156.
-
(1996)
Ir. Med. J.
, vol.89
, pp. 156
-
-
Delanty, N.1
Fitzgerald, D.J.2
-
7
-
-
2342613543
-
Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 mice
-
Goldring, C.E., Kitteringham, N.R., Elsby, R., Randle, L.E., Clement, Y.N., Williams, D.P., McMahon, M., Hayes, J.D., Itoh, K., Yamamoto, M. and Park, B.K. (2004) Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 mice. Hepatology, 39, 1267-1276.
-
(2004)
Hepatology
, vol.39
, pp. 1267-1276
-
-
Goldring, C.E.1
Kitteringham, N.R.2
Elsby, R.3
Randle, L.E.4
Clement, Y.N.5
Williams, D.P.6
McMahon, M.7
Hayes, J.D.8
Itoh, K.9
Yamamoto, M.10
Park, B.K.11
-
8
-
-
34548133006
-
Acetaminophen hepatotoxicity
-
Larson, A.M. (2007) Acetaminophen hepatotoxicity. Clin. Liver Dis., 11, 525-548.
-
(2007)
Clin. Liver Dis.
, vol.11
, pp. 525-548
-
-
Larson, A.M.1
-
9
-
-
13244292321
-
Mechanisms of acetaminophen-induced hepatotoxicity: role of oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes
-
Reid, A.B., Kurten, R.C., McCullough, S.S., Brock, R.W. and Hinson, J.A. (2005) Mechanisms of acetaminophen-induced hepatotoxicity: role of oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes. J. Pharmacol. Exp. Ther., 312, 509-516.
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.312
, pp. 509-516
-
-
Reid, A.B.1
Kurten, R.C.2
McCullough, S.S.3
Brock, R.W.4
Hinson, J.A.5
-
10
-
-
69749128688
-
Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans
-
Harrill, A.H., Watkins, P.B., Su, S., Ross, P.K., Harbourt, D.E., Stylianou, I.M., Boorman, G.A., Russo, M.W., Sackler, R.S., Harris, S.C., Smith, P.C., Tennant, R., Bogue, M., Paigen, K., Harris, C., Contractor, T., Wiltshire, T., Rusyn, I. and Threadgill, D.W. (2009) Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans. Genome Res., 19, 1507-1515.
-
(2009)
Genome Res.
, vol.19
, pp. 1507-1515
-
-
Harrill, A.H.1
Watkins, P.B.2
Su, S.3
Ross, P.K.4
Harbourt, D.E.5
Stylianou, I.M.6
Boorman, G.A.7
Russo, M.W.8
Sackler, R.S.9
Harris, S.C.10
Smith, P.C.11
Tennant, R.12
Bogue, M.13
Paigen, K.14
Harris, C.15
Contractor, T.16
Wiltshire, T.17
Rusyn, I.18
Threadgill, D.W.19
-
11
-
-
79952207647
-
HepaRG cells: a human model to study mechanisms of acetaminophen hepatotoxicity
-
McGill, M.R., Yan, H.M., Ramachandran, A., Murray, G.J., Rollins, D.E. and Jaeschke, H. (2011) HepaRG cells: a human model to study mechanisms of acetaminophen hepatotoxicity. Hepatology, 53, 974-982.
-
(2011)
Hepatology
, vol.53
, pp. 974-982
-
-
McGill, M.R.1
Yan, H.M.2
Ramachandran, A.3
Murray, G.J.4
Rollins, D.E.5
Jaeschke, H.6
-
12
-
-
0025171032
-
Glutathione-degrading capacities of liver and kidney in different species
-
Hinchman, C.A. and Ballatori, N. (1990) Glutathione-degrading capacities of liver and kidney in different species. Biochem. Pharmacol., 40, 1131-1135.
-
(1990)
Biochem. Pharmacol.
, vol.40
, pp. 1131-1135
-
-
Hinchman, C.A.1
Ballatori, N.2
-
13
-
-
64049104966
-
Effect of repeated administration with subtoxic doses of acetaminophen to rats on enterohepatic recirculation of a subsequent toxic dose
-
Ghanem, C.I., Ruiz, M.L., Villanueva, S.S., Luquita, M., Llesuy, S., Catania, V.A., Bengochea, L.A. and Mottino, A.D. (2009) Effect of repeated administration with subtoxic doses of acetaminophen to rats on enterohepatic recirculation of a subsequent toxic dose. Biochem. Pharmacol., 77, 1621-1628.
-
(2009)
Biochem. Pharmacol.
, vol.77
, pp. 1621-1628
-
-
Ghanem, C.I.1
Ruiz, M.L.2
Villanueva, S.S.3
Luquita, M.4
Llesuy, S.5
Catania, V.A.6
Bengochea, L.A.7
Mottino, A.D.8
-
14
-
-
40849120695
-
Hepatic synthesis and urinary elimination of acetaminophen glucuronide are exacerbated in bile duct-ligated rats
-
Villanueva, S.S., Ruiz, M.L., Ghanem, C.I., Luquita, M.G., Catania, V.A. and Mottino, A.D. (2008) Hepatic synthesis and urinary elimination of acetaminophen glucuronide are exacerbated in bile duct-ligated rats. Drug Metab. Dispos., 36, 475-480.
-
(2008)
Drug Metab. Dispos.
, vol.36
, pp. 475-480
-
-
Villanueva, S.S.1
Ruiz, M.L.2
Ghanem, C.I.3
Luquita, M.G.4
Catania, V.A.5
Mottino, A.D.6
-
15
-
-
78349236196
-
Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice
-
Williams, C.D., Bajt, M.L., Farhood, A. and Jaeschke, H. (2010) Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice. Liver Int., 30, 1280-1292.
-
(2010)
Liver Int.
, vol.30
, pp. 1280-1292
-
-
Williams, C.D.1
Bajt, M.L.2
Farhood, A.3
Jaeschke, H.4
-
16
-
-
0036304261
-
Mode of cell death after acetaminophen overdose in mice: apoptosis or oncotic necrosis?
-
Gujral, J.S., Knight, T.R., Farhood, A., Bajt, M.L. and Jaeschke, H. (2002) Mode of cell death after acetaminophen overdose in mice: apoptosis or oncotic necrosis? Toxicol. Sci., 67, 322-328.
-
(2002)
Toxicol. Sci.
, vol.67
, pp. 322-328
-
-
Gujral, J.S.1
Knight, T.R.2
Farhood, A.3
Bajt, M.L.4
Jaeschke, H.5
-
17
-
-
84867847425
-
Acetaminophen-induced liver injury in rats and mice: comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity
-
McGill, M.R., Williams, C.D., Xie, Y., Ramachandran, A. and Jaeschke, H. (2012) Acetaminophen-induced liver injury in rats and mice: comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity. Toxicol. Appl. Pharmacol., 264, 387-394.
-
(2012)
Toxicol. Appl. Pharmacol.
, vol.264
, pp. 387-394
-
-
McGill, M.R.1
Williams, C.D.2
Xie, Y.3
Ramachandran, A.4
Jaeschke, H.5
-
18
-
-
28144445947
-
Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity
-
Okawa, H., Motohashi, H., Kobayashi, A., Aburatani, H., Kensler, T.W. and Yamamoto, M. (2006) Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity. Biochem. Biophys. Res. Commun., 339, 79-88.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.339
, pp. 79-88
-
-
Okawa, H.1
Motohashi, H.2
Kobayashi, A.3
Aburatani, H.4
Kensler, T.W.5
Yamamoto, M.6
-
19
-
-
77649273272
-
Nrf2 the rescue: effects of the antioxidative/electrophilic response on the liver
-
Klaassen, C.D. and Reisman, S.A. (2010) Nrf2 the rescue: effects of the antioxidative/electrophilic response on the liver. Toxicol. Appl. Pharmacol., 244, 57-65.
-
(2010)
Toxicol. Appl. Pharmacol.
, vol.244
, pp. 57-65
-
-
Klaassen, C.D.1
Reisman, S.A.2
-
20
-
-
65549114152
-
Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice
-
Reisman, S.A., Csanaky, I.L., Aleksunes, L.M. and Klaassen, C.D. (2009) Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice. Toxicol. Sci., 109, 31-40.
-
(2009)
Toxicol. Sci.
, vol.109
, pp. 31-40
-
-
Reisman, S.A.1
Csanaky, I.L.2
Aleksunes, L.M.3
Klaassen, C.D.4
-
21
-
-
84878728657
-
The amelioration of Nacetyl-p-benzoquinone imine toxicity by ginsenoside Rg3: the role of Nrf2-mediated detoxification and Mrp1/Mrp3 transports
-
957947
-
Gum, S.I. and Cho, M.K. (2013) The amelioration of Nacetyl-p-benzoquinone imine toxicity by ginsenoside Rg3: the role of Nrf2-mediated detoxification and Mrp1/Mrp3 transports. Oxid. Med. Cell. Longevity, 2013, 957947.
-
(2013)
Oxid. Med. Cell. Longevity
, vol.2013
-
-
Gum, S.I.1
Cho, M.K.2
-
22
-
-
36849088620
-
Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2
-
Aleksunes, L.M., Slitt, A.L., Maher, J.M., Augustine, L.M., Goedken, M.J., Chan, J.Y., Cherrington, N.J., Klaassen, C.D. and Manautou, J.E. (2008) Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2. Toxicol. Appl. Pharmacol., 226, 74-83.
-
(2008)
Toxicol. Appl. Pharmacol.
, vol.226
, pp. 74-83
-
-
Aleksunes, L.M.1
Slitt, A.L.2
Maher, J.M.3
Augustine, L.M.4
Goedken, M.J.5
Chan, J.Y.6
Cherrington, N.J.7
Klaassen, C.D.8
Manautou, J.E.9
-
23
-
-
36349015332
-
Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway
-
Maher, J.M., Dieter, M.Z., Aleksunes, L.M., Slitt, A.L., Guo, G., Tanaka, Y., Scheffer, G.L., Chan, J.Y., Manautou, J.E., Chen, Y., Dalton, T.P., Yamamoto, M. and Klaassen, C.D. (2007) Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway. Hepatology, 46, 1597-1610.
-
(2007)
Hepatology
, vol.46
, pp. 1597-1610
-
-
Maher, J.M.1
Dieter, M.Z.2
Aleksunes, L.M.3
Slitt, A.L.4
Guo, G.5
Tanaka, Y.6
Scheffer, G.L.7
Chan, J.Y.8
Manautou, J.E.9
Chen, Y.10
Dalton, T.P.11
Yamamoto, M.12
Klaassen, C.D.13
-
24
-
-
33751104475
-
The important role of Bcrp (Abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice
-
Zamek-Gliszczynski, M.J., Nezasa, K., Tian, X., Kalvass, J.C., Patel, N.J., Raub, T.J. and Brouwer, K.L. (2006) The important role of Bcrp (Abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice. Mol. Pharmacol., 70, 2127-2133.
-
(2006)
Mol. Pharmacol.
, vol.70
, pp. 2127-2133
-
-
Zamek-Gliszczynski, M.J.1
Nezasa, K.2
Tian, X.3
Kalvass, J.C.4
Patel, N.J.5
Raub, T.J.6
Brouwer, K.L.7
-
25
-
-
0035153227
-
High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes
-
Enomoto, A., Itoh, K., Nagayoshi, E., Haruta, J., Kimura, T., O'Connor, T., Harada, T. and Yamamoto, M. (2001) High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes. Toxicol. Sci., 59, 169-177.
-
(2001)
Toxicol. Sci.
, vol.59
, pp. 169-177
-
-
Enomoto, A.1
Itoh, K.2
Nagayoshi, E.3
Haruta, J.4
Kimura, T.5
O'Connor, T.6
Harada, T.7
Yamamoto, M.8
-
26
-
-
84861466718
-
Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury
-
Ni, H.M., Boggess, N., McGill, M.R., Lebofsky, M., Borude, P., Apte, U., Jaeschke, H. and Ding, W.X. (2012) Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury. Toxicol. Sci., 127, 438-450.
-
(2012)
Toxicol. Sci.
, vol.127
, pp. 438-450
-
-
Ni, H.M.1
Boggess, N.2
McGill, M.R.3
Lebofsky, M.4
Borude, P.5
Apte, U.6
Jaeschke, H.7
Ding, W.X.8
-
27
-
-
84880322948
-
Disruption of thioredoxin reductase 1 protects mice from acute acetaminophen-induced hepatotoxicity through enhanced Nrf2 activity
-
Patterson, A.D., Carlson, B.A., Li, F., Bonzo, J.A., Yoo, M.H., Krausz, K.W., Conrad, M., Chen, C., Gonzalez, F.J. and Hatfield, D.L. (2013) Disruption of thioredoxin reductase 1 protects mice from acute acetaminophen-induced hepatotoxicity through enhanced Nrf2 activity. Chem. Res. Toxicol., 26, 1088-1096.
-
(2013)
Chem. Res. Toxicol.
, vol.26
, pp. 1088-1096
-
-
Patterson, A.D.1
Carlson, B.A.2
Li, F.3
Bonzo, J.A.4
Yoo, M.H.5
Krausz, K.W.6
Conrad, M.7
Chen, C.8
Gonzalez, F.J.9
Hatfield, D.L.10
-
28
-
-
84879407019
-
Protein tyrosine phosphatase 1B modulates GSK3beta/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity
-
Mobasher, M.A., González-Rodriguez, A., Santamaría, B., Ramos, S., Martin, M.Á., Goya, L., Rada, P., Letzig, L., James, L.P., Cuadrado, A., Martín-Pérez, J., Simpson, K.J., Muntané, J. and Valverde, A.M. (2013) Protein tyrosine phosphatase 1B modulates GSK3beta/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity. Cell Death Dis., 4, e626.
-
(2013)
Cell Death Dis.
, vol.4
-
-
Mobasher, M.A.1
González-Rodriguez, A.2
Santamaría, B.3
Ramos, S.4
Martin, M.Á.5
Goya, L.6
Rada, P.7
Letzig, L.8
James, L.P.9
Cuadrado, A.10
Martín-Pérez, J.11
Simpson, K.J.12
Muntané, J.13
Valverde, A.M.14
-
29
-
-
0018651356
-
Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning
-
Prescott, L.F., Illingworth, R.N., Critchley, J.A., Stewart, M.J., Adam, R.D. and Proudfoot, A.T. (1979) Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning. Br. Med. J., 2, 1097-1100.
-
(1979)
Br. Med. J.
, vol.2
, pp. 1097-1100
-
-
Prescott, L.F.1
Illingworth, R.N.2
Critchley, J.A.3
Stewart, M.J.4
Adam, R.D.5
Proudfoot, A.T.6
-
30
-
-
0036200123
-
Sulfur in human nutrition and applications in medicine
-
Parcell, S. (2002) Sulfur in human nutrition and applications in medicine. Altern. Med. Rev., 7, 22-44.
-
(2002)
Altern. Med. Rev.
, vol.7
, pp. 22-44
-
-
Parcell, S.1
-
31
-
-
18144436683
-
Influence of acute and chronic alcohol intake on the clinical course and outcome in acetaminophen overdose
-
Schiødt, F.V., Lee, W.M., Bondesen, S., Ott, P. and Christensen, E. (2002) Influence of acute and chronic alcohol intake on the clinical course and outcome in acetaminophen overdose. Aliment. Pharmacol. Ther., 16, 707-715.
-
(2002)
Aliment. Pharmacol. Ther.
, vol.16
, pp. 707-715
-
-
Schiødt, F.V.1
Lee, W.M.2
Bondesen, S.3
Ott, P.4
Christensen, E.5
-
32
-
-
0030852822
-
Cimetidine enhances the hepatoprotective action of N-acetylcysteine in mice treated with toxic doses of paracetamol
-
Al-Mustafa, Z.H., Al-Ali, A.K., Qaw, F.S. and Abdul-Cader, Z. (1997) Cimetidine enhances the hepatoprotective action of N-acetylcysteine in mice treated with toxic doses of paracetamol. Toxicology, 121, 223-228.
-
(1997)
Toxicology
, vol.121
, pp. 223-228
-
-
Al-Mustafa, Z.H.1
Al-Ali, A.K.2
Qaw, F.S.3
Abdul-Cader, Z.4
-
33
-
-
84880157962
-
Korean red ginseng extract prevents APAP-induced hepatotoxicity through metabolic enzyme regulation: The role of ginsenoside Rg3, a protopanaxadiol
-
Gum, S.I. and Cho, M.K. (2013) Korean red ginseng extract prevents APAP-induced hepatotoxicity through metabolic enzyme regulation: The role of ginsenoside Rg3, a protopanaxadiol. Liver Int., 33, 1071-1084.
-
(2013)
Liver Int.
, vol.33
, pp. 1071-1084
-
-
Gum, S.I.1
Cho, M.K.2
-
34
-
-
84872368207
-
Purinergic receptor antagonist A438079 protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation
-
Xie, Y., Williams, C.D., McGill, M.R., Lebofsky, M., Ramachandran, A. and Jaeschke, H. (2013) Purinergic receptor antagonist A438079 protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation. Toxicol. Sci., 131, 325-335.
-
(2013)
Toxicol. Sci.
, vol.131
, pp. 325-335
-
-
Xie, Y.1
Williams, C.D.2
McGill, M.R.3
Lebofsky, M.4
Ramachandran, A.5
Jaeschke, H.6
-
35
-
-
0030247013
-
Protection by clofibrate against acetaminophen hepatotoxicity in male CD-1 mice is associated with an early increase in biliary concentration of acetaminophenglutathione adducts
-
Manautou, J.E., Tveit, A., Hoivik, D.J., Khairallah, E.A. and Cohen, S.D. (1996) Protection by clofibrate against acetaminophen hepatotoxicity in male CD-1 mice is associated with an early increase in biliary concentration of acetaminophenglutathione adducts. Toxicol. Appl. Pharmacol., 140, 30-38.
-
(1996)
Toxicol. Appl. Pharmacol.
, vol.140
, pp. 30-38
-
-
Manautou, J.E.1
Tveit, A.2
Hoivik, D.J.3
Khairallah, E.A.4
Cohen, S.D.5
-
36
-
-
0022531353
-
Effects of butylated hydroxyanisole on acetaminophen hepatotoxicity and glucuronidation in vivo
-
Hazelton, G.A., Hjelle, J.J. and Klaassen, C.D. (1986) Effects of butylated hydroxyanisole on acetaminophen hepatotoxicity and glucuronidation in vivo. Toxicol. Appl. Pharmacol., 83, 474-485.
-
(1986)
Toxicol. Appl. Pharmacol.
, vol.83
, pp. 474-485
-
-
Hazelton, G.A.1
Hjelle, J.J.2
Klaassen, C.D.3
-
37
-
-
61449208761
-
Oleanolic acid activates Nrf2 and protects from acetaminophen hepatotoxicity via Nrf2-dependent and Nrf2-independent processes
-
Reisman, S.A., Aleksunes, L.M. and Klaassen, C.D. (2009) Oleanolic acid activates Nrf2 and protects from acetaminophen hepatotoxicity via Nrf2-dependent and Nrf2-independent processes. Biochem. Pharmacol., 77, 1273-1282.
-
(2009)
Biochem. Pharmacol.
, vol.77
, pp. 1273-1282
-
-
Reisman, S.A.1
Aleksunes, L.M.2
Klaassen, C.D.3
-
38
-
-
84893718511
-
Role of Nrf2 in protection against acute kidney injury
-
Shelton, L.M., Park, B.K. and Copple, I.M. (2013) Role of Nrf2 in protection against acute kidney injury. Kidney Int., 47, 698-706.
-
(2013)
Kidney Int.
, vol.47
, pp. 698-706
-
-
Shelton, L.M.1
Park, B.K.2
Copple, I.M.3
-
39
-
-
0242468790
-
Possible mechanism of hepatoprotective activity of Azadirachta indica leaf extract: part II
-
Chattopadhyay, R.R. (2003) Possible mechanism of hepatoprotective activity of Azadirachta indica leaf extract: part II. J. Ethnopharmacol., 89, 217-219.
-
(2003)
J. Ethnopharmacol.
, vol.89
, pp. 217-219
-
-
Chattopadhyay, R.R.1
-
40
-
-
84864592926
-
Moringa oleifera hydroethanolic extracts effectively alleviate acetaminophen-induced hepatotoxicity in experimental rats through their antioxidant nature
-
Fakurazi, S., Sharifudin, S.A. and Arulselvan, P. (2012) Moringa oleifera hydroethanolic extracts effectively alleviate acetaminophen-induced hepatotoxicity in experimental rats through their antioxidant nature. Molecules, 17, 8334-8350.
-
(2012)
Molecules
, vol.17
, pp. 8334-8350
-
-
Fakurazi, S.1
Sharifudin, S.A.2
Arulselvan, P.3
-
41
-
-
0842307097
-
Protective effect of Moutan Cortex extract on acetaminophen-induced hepatotoxicity in mice
-
Shon, Y.H. and Nam, K.S. (2004) Protective effect of Moutan Cortex extract on acetaminophen-induced hepatotoxicity in mice. J. Ethnopharmacol., 90, 415-419.
-
(2004)
J. Ethnopharmacol.
, vol.90
, pp. 415-419
-
-
Shon, Y.H.1
Nam, K.S.2
-
42
-
-
0035841944
-
Hepatoprotective effects of Platycodon grandiflorum on acetaminophen-induced liver damage in mice
-
Lee, K.J., You, H.J., Park, S.J., Kim, Y.S., Chung, Y.C., Jeong, T.C. and Jeong, H.G. (2001) Hepatoprotective effects of Platycodon grandiflorum on acetaminophen-induced liver damage in mice. Cancer Lett., 174, 73-81.
-
(2001)
Cancer Lett.
, vol.174
, pp. 73-81
-
-
Lee, K.J.1
You, H.J.2
Park, S.J.3
Kim, Y.S.4
Chung, Y.C.5
Jeong, T.C.6
Jeong, H.G.7
-
43
-
-
84856286822
-
In Vitro Cell
-
Kavitha, P., Ramesh, R., Bupesh, G., Stalin, A. and Subramanian, P. (2011) Hepatoprotective activity of Tribulus terrestris extract against acetaminophen-induced toxicity in a freshwa ter fish (Oreochromis mossambicus). In Vitro Cell. Dev. Biol. Anim., 47, 698-706.
-
(2011)
Dev. Biol. Anim.
, vol.47
, pp. 698-706
-
-
Kavitha, P.1
Ramesh, R.2
Bupesh, G.3
Stalin, A.4
Subramanian, P.5
-
44
-
-
0033821622
-
Effect of liquid extract from fresh Abutilon indicum leaves and Allium cepa bulbs on paracetamol and carbontetrachloride induced hepatotoxicity
-
Porchezhian, E. and Ansari, S.H. (2000) Effect of liquid extract from fresh Abutilon indicum leaves and Allium cepa bulbs on paracetamol and carbontetrachloride induced hepatotoxicity. Pharmazie, 55, 702-703.
-
(2000)
Pharmazie
, vol.55
, pp. 702-703
-
-
Porchezhian, E.1
Ansari, S.H.2
-
45
-
-
0027525348
-
Protective effect of Artemisia scoparia extract against acetaminophen-induced hepatotoxicity
-
Gilani, A.H. and Janbaz, K.H. (1993) Protective effect of Artemisia scoparia extract against acetaminophen-induced hepatotoxicity. Gen. Pharmacol., 24, 1455-1458.
-
(1993)
Gen. Pharmacol.
, vol.24
, pp. 1455-1458
-
-
Gilani, A.H.1
Janbaz, K.H.2
-
46
-
-
0031006538
-
Hepatoprotective effect of the fractions of Ban-zhi-lian on experimental liver injuries in rats
-
Lin, C.C., Shieh, D.E. and Yen, M.H. (1997) Hepatoprotective effect of the fractions of Ban-zhi-lian on experimental liver injuries in rats. J. Ethnopharmacol., 56, 193-200.
-
(1997)
J. Ethnopharmacol.
, vol.56
, pp. 193-200
-
-
Lin, C.C.1
Shieh, D.E.2
Yen, M.H.3
-
47
-
-
40849101564
-
Nanoparticles formulation of Cuscuta chinensis prevents acetaminophen-induced hepatotoxicity in rats
-
Yen, F.L., Wu, T.H., Lin, L.T., Cham, T.M. and Lin, C.C. (2008) Nanoparticles formulation of Cuscuta chinensis prevents acetaminophen-induced hepatotoxicity in rats. Food Chem. Toxicol., 46, 1771-1777.
-
(2008)
Food Chem. Toxicol.
, vol.46
, pp. 1771-1777
-
-
Yen, F.L.1
Wu, T.H.2
Lin, L.T.3
Cham, T.M.4
Lin, C.C.5
-
48
-
-
0028910423
-
Studies on protective effect of Cyperus scariosus extract on acetaminophen and CCl4-induced hepatotoxicity
-
Gilani, A.U. and Janbaz, K.H. (1995) Studies on protective effect of Cyperus scariosus extract on acetaminophen and CCl4-induced hepatotoxicity. Gen. Pharmacol., 26, 627-631.
-
(1995)
Gen. Pharmacol.
, vol.26
, pp. 627-631
-
-
Gilani, A.U.1
Janbaz, K.H.2
-
49
-
-
0030250470
-
Selective protective effect of an extract from Fumaria parviflora on paracetamol-induced hepatotoxicity
-
Gilani, A.H., Janbaz, K.H. and Akhtar, M.S. (1996) Selective protective effect of an extract from Fumaria parviflora on paracetamol-induced hepatotoxicity. Gen. Pharmacol, 27, 979-983.
-
(1996)
Gen. Pharmacol
, vol.27
, pp. 979-983
-
-
Gilani, A.H.1
Janbaz, K.H.2
Akhtar, M.S.3
-
50
-
-
77953761200
-
The effect of the aqueous extract of Kohautia grandiflora on paracetamolinduced liver damage in albino rats
-
Garba, S.H., Sambo, N. and Bala, U. (2009) The effect of the aqueous extract of Kohautia grandiflora on paracetamolinduced liver damage in albino rats. Niger. J. Physiol. Sci., 24, 17-23.
-
(2009)
Niger. J. Physiol. Sci.
, vol.24
, pp. 17-23
-
-
Garba, S.H.1
Sambo, N.2
Bala, U.3
-
51
-
-
78049476186
-
Protective effects of Pergularia daemia roots against paracetamol and carbon tetrachloride-induced hepatotoxicity in rats
-
Bhaskar, V.H. and Balakrishnan, N. (2010) Protective effects of Pergularia daemia roots against paracetamol and carbon tetrachloride-induced hepatotoxicity in rats. Pharm. Biol., 48, 1265-1272.
-
(2010)
Pharm. Biol.
, vol.48
, pp. 1265-1272
-
-
Bhaskar, V.H.1
Balakrishnan, N.2
-
52
-
-
67349162779
-
Phyllanthus urinaria extract attenuates acetaminophen induced hepatotoxicity: involvement of cytochrome P450 CYP2E1
-
Hau, D.K., Gambari, R., Wong, R.S., Yuen, M.C., Cheng, G.Y., Tong, C.S., Zhu, G.Y., Leung, A.K., Lai, P.B., Lau, F.Y., Chan, A.K., Wong, W.Y., Kok, S.H., Cheng, C.H., Kan, C.W., Chan, A.S., Chui, C.H., Tang, J.C. and Fong, D.W. (2009) Phyllanthus urinaria extract attenuates acetaminophen induced hepatotoxicity: involvement of cytochrome P450 CYP2E1. Phytomedicine, 16, 751-760.
-
(2009)
Phytomedicine
, vol.16
, pp. 751-760
-
-
Hau, D.K.1
Gambari, R.2
Wong, R.S.3
Yuen, M.C.4
Cheng, G.Y.5
Tong, C.S.6
Zhu, G.Y.7
Leung, A.K.8
Lai, P.B.9
Lau, F.Y.10
Chan, A.K.11
Wong, W.Y.12
Kok, S.H.13
Cheng, C.H.14
Kan, C.W.15
Chan, A.S.16
Chui, C.H.17
Tang, J.C.18
Fong, D.W.19
-
53
-
-
0033644043
-
The hepatoprotective effects of Solanum alatum Moench. on acetaminopheninduced hepatotoxicity in mice
-
Lin, S.C., Chung, T.C., Ueng, T.H., Lin, Y.H., Hsu, S.H., Chiang, C.L. and Lin, C.C. (2000) The hepatoprotective effects of Solanum alatum Moench. on acetaminopheninduced hepatotoxicity in mice. Am. J. Chin. Med., 28, 105-114.
-
(2000)
Am. J. Chin. Med.
, vol.28
, pp. 105-114
-
-
Lin, S.C.1
Chung, T.C.2
Ueng, T.H.3
Lin, Y.H.4
Hsu, S.H.5
Chiang, C.L.6
Lin, C.C.7
-
54
-
-
31544476899
-
Protective effects of Swertia longifolia Boiss. and its active compound, swerchirin, on paracetamol-induced hepatotoxicity in mice
-
Hajimehdipoor, H., Sadeghi, Z., Elmi, S., Elmi, A., Ghazi-Khansari, M., Amanzadeh, Y. and Sadat-Ebrahimi, S.E. (2006) Protective effects of Swertia longifolia Boiss. and its active compound, swerchirin, on paracetamol-induced hepatotoxicity in mice. J. Pharm. Pharmacol., 58, 277-280.
-
(2006)
J. Pharm. Pharmacol.
, vol.58
, pp. 277-280
-
-
Hajimehdipoor, H.1
Sadeghi, Z.2
Elmi, S.3
Elmi, A.4
Ghazi-Khansari, M.5
Amanzadeh, Y.6
Sadat-Ebrahimi, S.E.7
-
55
-
-
84984593060
-
Antioxidant properties of Taraxacum officinale leaf extract are involved in the protective effect against hepatoxicity induced by acetaminophen in mice
-
Colle, D., Arantes, L.P., Gubert, P., da Luz, S.C., Athayde, M.L., Teixeira Rocha, J.B. and Soares, F.A. (2012) Antioxidant properties of Taraxacum officinale leaf extract are involved in the protective effect against hepatoxicity induced by acetaminophen in mice. J. Med. Food, 15, 549-556.
-
(2012)
J. Med. Food
, vol.15
, pp. 549-556
-
-
Colle, D.1
Arantes, L.P.2
Gubert, P.3
da Luz, S.C.4
Athayde, M.L.5
Teixeira Rocha, J.B.6
Soares, F.A.7
-
56
-
-
0031874599
-
Hepatoprotective activity of Trichopus zeylanicus extract against paracetamol-induced hepatic damage in rats
-
Subramoniam, A., Evans, D.A., Rajasekharan, S. and Pushpangadan, P. (1998) Hepatoprotective activity of Trichopus zeylanicus extract against paracetamol-induced hepatic damage in rats. Indian J. Exp. Biol., 36, 385-389.
-
(1998)
Indian J. Exp. Biol.
, vol.36
, pp. 385-389
-
-
Subramoniam, A.1
Evans, D.A.2
Rajasekharan, S.3
Pushpangadan, P.4
-
57
-
-
79959605086
-
Protective effect of Woodfordia fruticosa flowers against acetaminophen-induced hepatic toxicity in rats
-
Baravalia, Y. and Chanda, S. (2011) Protective effect of Woodfordia fruticosa flowers against acetaminophen-induced hepatic toxicity in rats. Pharm. Biol., 49, 826-832.
-
(2011)
Pharm. Biol.
, vol.49
, pp. 826-832
-
-
Baravalia, Y.1
Chanda, S.2
|