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Volumn 17, Issue 7, 2012, Pages 8334-8350

Moringa oleifera Hydroethanolic extracts effectively alleviate acetaminophen-induced hepatotoxicity in experimental rats through their antioxidant nature

Author keywords

Antioxidants; Hepatoprotection; Lipid peroxidation; Liver markers; N acetylcysteine; Total phenolic content

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2,2-DIPHENYL-1-PICRYLHYDRAZYL; 4 HYDROXYNONENAL; 4-HYDROXY-2-NONENAL; ALCOHOL; ALDEHYDE; ANTIOXIDANT; BIOLOGICAL MARKER; BIPHENYL DERIVATIVE; GLUTATHIONE; MALONALDEHYDE; PARACETAMOL; PHENOL DERIVATIVE; PICRIC ACID; PLANT EXTRACT; SCAVENGER; WATER;

EID: 84864592926     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules17078334     Document Type: Article
Times cited : (102)

References (71)
  • 1
    • 79957852763 scopus 로고    scopus 로고
    • Protective effects of hyperoside against carbon tetrachloride-induced liver damage in mice
    • Choi, J.H.; Kim, D.W.; Yun, N.; Choi, J.S.; Islam, M.N.; Kim, Y.S.; Lee, S.M. Protective effects of hyperoside against carbon tetrachloride-induced liver damage in mice. J. Nat. Prod. 2011, 74, 1055-1060.
    • (2011) J. Nat. Prod , vol.74 , pp. 1055-1060
    • Choi, J.H.1    Kim, D.W.2    Yun, N.3    Choi, J.S.4    Islam, M.N.5    Kim, Y.S.6    Lee, S.M.7
  • 2
    • 74149084416 scopus 로고    scopus 로고
    • And antioxidant activity of ethanolic extracts of edible lotus (Nelumbo nucifera Gaertn.) leaves
    • Huang, B.; Ban, X.; He, J.; Tong, J.; Tian, J.; Wang, Y. Hepatoprotective and antioxidant activity of ethanolic extracts of edible lotus (Nelumbo nucifera Gaertn.) leaves. Food Chem. 2010, 120, 873-878.
    • (2010) Food Chem , vol.120 , pp. 873-878
    • Huang, B.1    Ban, X.2    He, J.3    Tong, J.4    Tian, J.5    Hepatoprotective, W.Y.6
  • 3
    • 79251605782 scopus 로고    scopus 로고
    • Hepatoprotective activity of Glycosmis pentaphylla against paracetamol-induced hepatotoxicity in Swiss albino mice
    • Nayak, S.S.; Jain, R.; Sahoo, A.K. Hepatoprotective activity of Glycosmis pentaphylla against paracetamol-induced hepatotoxicity in Swiss albino mice. Pharm. Biol. 2011, 49, 111-117.
    • (2011) Pharm. Biol , vol.49 , pp. 111-117
    • Nayak, S.S.1    Jain, R.2    Sahoo, A.K.3
  • 4
    • 78049476186 scopus 로고    scopus 로고
    • Protective effects of Pergularia daemia roots against paracetamol and carbon tetrachloride-induced hepatotoxicity in rats
    • Bhaskar, V.H.; Balakrishnan, N. Protective effects of Pergularia daemia roots against paracetamol and carbon tetrachloride-induced hepatotoxicity in rats. Pharm. Biol. 2010, 48, 1265-1272.
    • (2010) Pharm. Biol , vol.48 , pp. 1265-1272
    • Bhaskar, V.H.1    Balakrishnan, N.2
  • 5
    • 47149118870 scopus 로고    scopus 로고
    • Moringa oleifera Lam prevents acetaminophen induced liver injury through restoration of glutathione level
    • Fakurazi, S.; Hairuszah, I.; Nanthini, U. Moringa oleifera Lam prevents acetaminophen induced liver injury through restoration of glutathione level. Food Chem. Toxicol. 2008, 46, 2611-2615.
    • (2008) Food Chem. Toxicol , vol.46 , pp. 2611-2615
    • Fakurazi, S.1    Hairuszah, I.2    Nanthini, U.3
  • 6
    • 84984585914 scopus 로고    scopus 로고
    • Water-extractable phytochemicals from Phyllanthus niruri exhibit distinct in vitro antioxidant and in vivo hepatoprotective activity against paracetamol-induced liver damage in mice
    • Sabir, S.M.; Rocha, J.B. Water-extractable phytochemicals from Phyllanthus niruri exhibit distinct in vitro antioxidant and in vivo hepatoprotective activity against paracetamol-induced liver damage in mice. Food Chem. 2008, 111, 845-851.
    • (2008) Food Chem , vol.111 , pp. 845-851
    • Sabir, S.M.1    Rocha, J.B.2
  • 7
    • 77957337417 scopus 로고    scopus 로고
    • Potential protective effects of quercetin and curcumin on paracetamol-induced histological changes, oxidative stress, impaired liver and kidney functions and haematotoxicity in rat
    • Yousef, M.I.; Omar, S.A.; El-Guendi, M.I.; Abdelmegid, L.A. Potential protective effects of quercetin and curcumin on paracetamol-induced histological changes, oxidative stress, impaired liver and kidney functions and haematotoxicity in rat. Food Chem. Toxicol. 2010, 48, 3246-3261.
    • (2010) Food Chem. Toxicol , vol.48 , pp. 3246-3261
    • Yousef, M.I.1    Omar, S.A.2    El-Guendi, M.I.3    Abdelmegid, L.A.4
  • 8
    • 67649547144 scopus 로고    scopus 로고
    • Hepatoprotective effects of an anthocyanin fraction from purple-fleshed sweet potato against acetaminopheninduced liver damage in mice
    • Choi, J.H.; Choi, C.Y.; Lee, K.J.; Hwang, Y.P.; Chung, Y.C.; Jeong, H.G. Hepatoprotective effects of an anthocyanin fraction from purple-fleshed sweet potato against acetaminopheninduced liver damage in mice. J. Med. Food 2009, 12, 320-326.
    • (2009) J. Med. Food , vol.12 , pp. 320-326
    • Choi, J.H.1    Choi, C.Y.2    Lee, K.J.3    Hwang, Y.P.4    Chung, Y.C.5    Jeong, H.G.6
  • 9
    • 79955628725 scopus 로고    scopus 로고
    • Hepatoprotective potential of aqueous extract of Butea monosperma against CCl4 induced damageinrats
    • Sharma, N.; Shukla, S. Hepatoprotective potential of aqueous extract of Butea monosperma against CCl4 induced damageinrats. Exp. Toxicol. Pathol. 2011, 63, 671-676.
    • (2011) Exp. Toxicol. Pathol , vol.63 , pp. 671-676
    • Sharma, N.1    Shukla, S.2
  • 10
    • 72949087713 scopus 로고    scopus 로고
    • Acetaminophen perturbed redox homeostasis in Wistar rat liver: Protective role of aqueous Pterocarpus osun leaf extract
    • Ajiboye, T.O.; Salau, A.K.; Yakubu, M.T.; Oladiji, A.T.; Akanji, M.A.; Okogun, J.I. Acetaminophen perturbed redox homeostasis in Wistar rat liver: Protective role of aqueous Pterocarpus osun leaf extract. Drug Chem. Toxicol. 2010, 33, 77-87.
    • (2010) Drug Chem. Toxicol , vol.33 , pp. 77-87
    • Ajiboye, T.O.1    Salau, A.K.2    Yakubu, M.T.3    Oladiji, A.T.4    Akanji, M.A.5    Okogun, J.I.6
  • 11
    • 69249120507 scopus 로고    scopus 로고
    • Protective activity of the stem bark aqueous extract of Musanga cecropioides in carbon tetrachloride- and acetaminophen-induced acute hepatotoxicity in rats
    • Adeneye, A.A. Protective activity of the stem bark aqueous extract of Musanga cecropioides in carbon tetrachloride- and acetaminophen-induced acute hepatotoxicity in rats. Afr. J. Tradit. Complement Altern. Med. 2009, 6, 131-138.
    • (2009) Afr. J. Tradit. Complement Altern. Med , vol.6 , pp. 131-138
    • Adeneye, A.A.1
  • 14
    • 61549115347 scopus 로고    scopus 로고
    • Grape products and cardiovascular disease risk factors
    • Pérez-Jiménez, J.; Saura-Calixto, F. Grape products and cardiovascular disease risk factors. Nutr. Res. Rev. 2008, 21, 158-173.
    • (2008) Nutr. Res. Rev , vol.21 , pp. 158-173
    • Pérez-Jiménez, J.1    Saura-Calixto, F.2
  • 15
    • 0033859612 scopus 로고    scopus 로고
    • Flavonoids as antioxidants
    • Pietta, P.G. Flavonoids as antioxidants. J. Nat. Prod. 2000, 63, 1035-1042.
    • (2000) J. Nat. Prod , vol.63 , pp. 1035-1042
    • Pietta, P.G.1
  • 17
    • 0347450628 scopus 로고    scopus 로고
    • Improvement of drumstick (Moringa pterygosperma Gaertn.) A unique source of food and medicine through tissue culture
    • Mughal, M.H.S.; Ali, G.; Srivastava, P.S.; Iqbal, M. Improvement of drumstick (Moringa pterygosperma Gaertn.) A unique source of food and medicine through tissue culture. Hamdard Med. 1999, 42, 37-42.
    • (1999) Hamdard Med , vol.42 , pp. 37-42
    • Mughal, M.H.S.1    Ali, G.2    Srivastava, P.S.3    Iqbal, M.4
  • 18
    • 33846647837 scopus 로고    scopus 로고
    • Moringa oleifera: A food plant with multiple medicinal uses
    • DOI 10.1002/ptr.2023
    • Anwar, F.; Latif, S.; Ashraf, M.; Gilani, A.H. Moringa oleifera: A food plant with multiple medicinal uses. Phytother. Res. 2007, 21, 17-25. (Pubitemid 46173903)
    • (2007) Phytotherapy Research , vol.21 , Issue.1 , pp. 17-25
    • Anwar, F.1    Latif, S.2    Ashraf, M.3    Gilani, A.H.4
  • 19
    • 77953796063 scopus 로고    scopus 로고
    • Evaluation of the polyphenol content and antioxidant properties of methanol extracts of the leaves, stem, and root barks of Moringa oleifera Lam
    • Atawodi, S.E.; Atawodi, J.C.; Idakwo, G.A.; Pfundstein, B.; Haubner, R.; Wurtele, G.; Bartsch, H.; Owen, R.W. Evaluation of the polyphenol content and antioxidant properties of methanol extracts of the leaves, stem, and root barks of Moringa oleifera Lam. J. Med. Food 2010, 13, 710-716.
    • (2010) J. Med. Food , vol.13 , pp. 710-716
    • Atawodi, S.E.1    Atawodi, J.C.2    Idakwo, G.A.3    Pfundstein, B.4    Haubner, R.5    Wurtele, G.6    Bartsch, H.7    Owen, R.W.8
  • 20
    • 0345708284 scopus 로고    scopus 로고
    • Antioxidant Action of Moringa oleifera Lam. (Drumstick) Against Antitubercular Drugs Induced Lipid Peroxidation in Rats
    • Ashok Kumar, N.; Pari, L. Antioxidant action of Moringa oleifera Lam. (drumstick) against antitubercular drugs induced lipid peroxidation in rats. J. Med. Food 2003, 6, 255-259. (Pubitemid 37445038)
    • (2003) Journal of Medicinal Food , vol.6 , Issue.3 , pp. 255-259
    • Kumar, N.A.1    Pari, L.2
  • 21
    • 33745959003 scopus 로고    scopus 로고
    • Evaluation of antioxidant activity of some plant extracts and their heat, pH and storage stability
    • DOI 10.1016/j.foodchem.2005.11.014, PII S0308814605009830
    • Arabshahi, D.S.; Devi, V.; Urooj, A. Evaluation of antioxidant activity of some plant extracts and their heat, pH and storage stability. Food Chem. 2007, 100, 1100-1105. (Pubitemid 44062192)
    • (2007) Food Chemistry , vol.100 , Issue.3 , pp. 1100-1105
    • Arabshahi-D, S.1    Vishalakshi Devi, D.2    Urooj, A.3
  • 22
    • 67949104877 scopus 로고    scopus 로고
    • In vitro and in vivo antioxidant properties of different fractions of Moringa oleifera leaves
    • Verma, A.R.; Vijayakumar, M.; Mathela, C.S.; Rao, C.V. In vitro and in vivo antioxidant properties of different fractions of Moringa oleifera leaves. Food Chem. Toxicol. 2009, 47, 2196-2201.
    • (2009) Food Chem. Toxicol , vol.47 , pp. 2196-2201
    • Verma, A.R.1    Vijayakumar, M.2    Mathela, C.S.3    Rao, C.V.4
  • 23
    • 80052527787 scopus 로고    scopus 로고
    • Modulatory effects of Moringa oleifera extracts against hydrogen peroxide-induced cytotoxicity and oxidative damage
    • Sreelatha, S.; Padma, P.R. Modulatory effects of Moringa oleifera extracts against hydrogen peroxide-induced cytotoxicity and oxidative damage. Hum. Exp. Toxicol. 2011, 30, 1359-1368.
    • (2011) Hum. Exp. Toxicol , vol.30 , pp. 1359-1368
    • Sreelatha, S.1    Padma, P.R.2
  • 24
    • 0036755139 scopus 로고    scopus 로고
    • Hepatoprotective activity of Moringa oleifera on antitubercular drug-induced liver damage in rats
    • Pari, L.; Kumar, N.A. Hepatoprotective activity of Moringa oleifera on antitubercular druginduced liver damage in rats. J. Med. Food 2002, 5, 171-177. (Pubitemid 35283422)
    • (2002) Journal of Medicinal Food , vol.5 , Issue.3 , pp. 171-177
    • Pari, L.1    Kumar, N.A.2
  • 25
    • 72149110415 scopus 로고    scopus 로고
    • Curcuma longa, Glycyrrhiza glabra and Moringa oleifera ameliorate diclofenacinduced hepatoxicity in rats
    • Hamza, A.A. Curcuma longa, Glycyrrhiza glabra and Moringa oleifera ameliorate diclofenacinduced hepatoxicity in rats. Am. J. Pharm. Toxicol. 2007, 2, 80-88.
    • (2007) Am. J. Pharm. Toxicol , vol.2 , pp. 80-88
    • Hamza, A.A.1
  • 26
    • 77956599724 scopus 로고    scopus 로고
    • Protective mechanisms of Moringa oleifera against CCl(4)-induced oxidative stress in precision-cut liver slices
    • Sreelatha, S.; Padma, P.R. Protective mechanisms of Moringa oleifera against CCl(4)-induced oxidative stress in precision-cut liver slices. Forsch Komplementmed 2010, 17, 189-194.
    • (2010) Forsch Komplementmed , vol.17 , pp. 189-194
    • Sreelatha, S.1    Padma, P.R.2
  • 27
    • 78049507800 scopus 로고    scopus 로고
    • Moringa oleifera enhances liver antioxidant status via elevations of antioxidant enzymes activity and counteracts paracetamol-induced hepatotoxicity
    • Uma, N.; Fakurazi, S.; Hairuszah, I. Moringa oleifera enhances liver antioxidant status via elevations of antioxidant enzymes activity and counteracts paracetamol-induced hepatotoxicity. Malayas. J. Nutr. 2010, 16, 293-307.
    • (2010) Malayas. J. Nutr , vol.16 , pp. 293-307
    • Uma, N.1    Fakurazi, S.2    Hairuszah, I.3
  • 28
    • 0142245495 scopus 로고    scopus 로고
    • Chemomodulatory effect of Moringa oleifera, Lam, on hepatic carcinogen metabolising enzymes, antioxidant parameters and skin papillomagenesis in mice
    • Bharali, R.; Tabassum, J.; Azad, M.R. Chemomodulatory effect of Moringa oleifera, Lam, on hepatic carcinogen metabolising enzymes, antioxidant parameters and skin papillomagenesis in mice. Asian Pac. J. Cancer Prev. 2003, 4, 131-139.
    • (2003) Asian Pac. J. Cancer Prev , vol.4 , pp. 131-139
    • Bharali, R.1    Tabassum, J.2    Azad, M.R.3
  • 29
    • 20544434380 scopus 로고    scopus 로고
    • A simple purification and activity assay of the coagulant protein from Moringa oleifera seed
    • DOI 10.1016/j.watres.2005.04.012, PII S0043135405001612
    • Ghebremichael, K.A.; Gunaratna, K.R.; Henriksson, H.; Brumer, H.; Dalhammar, G. A simple purification and activity assay of the coagulant protein from Moringa oleifera seed. Water Res. 2005, 39, 2338-2344. (Pubitemid 40840688)
    • (2005) Water Research , vol.39 , Issue.11 , pp. 2338-2344
    • Ghebremichael, K.A.1    Gunaratna, K.R.2    Henriksson, H.3    Brumer, H.4    Dalhammar, G.5
  • 30
    • 0032958628 scopus 로고    scopus 로고
    • Compositional and nutritional attributes of seeds from the multiple purpose tree Moringa oleifera Lamarck
    • DOI 10.1002/(SICI)1097-0010(19990501)79:6<815::AID-JSFA290>3.0. CO;2-P
    • Oliveira, J.T.; Silveira, S.B.; Vasconcelos, I.M.; Cavada, B.S.; Moreira, R.A. Compositional and nutritional attributes of seeds from the multiple purpose tree Moringa oleifera Lamarck. J. Sci. Food Agric. 1999, 79, 815-820. (Pubitemid 29211975)
    • (1999) Journal of the Science of Food and Agriculture , vol.79 , Issue.6 , pp. 815-820
    • Oliveira, J.T.A.1    Silveira, S.B.2    Vasconcelos, I.M.3    Cavada, B.S.4    Moreira, R.A.5
  • 31
    • 33646073738 scopus 로고    scopus 로고
    • Phenolic compounds in plants and agri-industrial by-products: Antioxidant activity, occurrence, and potential uses
    • Balasundram, N.; Sundram, K.; Samman, S. Phenolic compounds in plants and agri-industrial by-products: Antioxidant activity, occurrence, and potential uses. Food Chem. 2006, 99, 191-203.
    • (2006) Food Chem , vol.99 , pp. 191-203
    • Balasundram, N.1    Sundram, K.2    Samman, S.3
  • 32
    • 33646406810 scopus 로고    scopus 로고
    • Simultaneous determination of catechin, rutin, quercetin kaempferol and isorhamnetin in the extract of sea buckthorn (Hippophae rhamnoides L.) leaves by RP-HPLC with DAD
    • Zu, Y.; Li, C.; Fu, Y.; Zhao, C. Simultaneous determination of catechin, rutin, quercetin kaempferol and isorhamnetin in the extract of sea buckthorn (Hippophae rhamnoides L.) leaves by RP-HPLC with DAD. J. Pharm. Biomed. Anal. 2006, 41, 714-719.
    • (2006) J. Pharm. Biomed. Anal , vol.41 , pp. 714-719
    • Zu, Y.1    Li, C.2    Fu, Y.3    Zhao, C.4
  • 34
    • 0034666458 scopus 로고    scopus 로고
    • Phytochemicals: Nutraceuticals and human health
    • DOI 10.1002/1097-0010(20000915)80:12<1744::AID-JSFA725>3.0.CO;2-W
    • Dillard, C.J.; German, J.B. Phytochemicals: nutraceuticals and human health. J. Sci. Food Agric. 2000, 80, 1744-1756. (Pubitemid 30656654)
    • (2000) Journal of the Science of Food and Agriculture , vol.80 , Issue.12 , pp. 1744-1756
    • Dillard, C.J.1    Bruce German, J.2
  • 36
    • 33947588994 scopus 로고    scopus 로고
    • Hepatoprotective and antioxidant effects of Cuscuta chinensis against acetaminophen-induced hepatotoxicity in rats
    • Yen, F.L.; Wu, T.H.; Lin, L.T.; Lin, C.C. Hepatoprotective and antioxidant effects of Cuscuta chinensis against acetaminophen-induced hepatotoxicity in rats. J. Ethnopharmacol. 2007, 111, 123-128.
    • (2007) J. Ethnopharmacol , vol.111 , pp. 123-128
    • Yen, F.L.1    Wu, T.H.2    Lin, L.T.3    Lin, C.C.4
  • 37
    • 55949094554 scopus 로고    scopus 로고
    • Effect of air-drying temperature on antioxidant capacity and stability of polyphenolic compounds in mulberry (Morus alba L.) leaves
    • Katsube, T.; Tsurunaga, Y.; Sugiyama, M.; Furuno, T.; Yamasaki, Y. Effect of air-drying temperature on antioxidant capacity and stability of polyphenolic compounds in mulberry (Morus alba L.) leaves. Food Chem. 2009, 113, 964-969.
    • (2009) Food Chem , vol.113 , pp. 964-969
    • Katsube, T.1    Tsurunaga, Y.2    Sugiyama, M.3    Furuno, T.4    Yamasaki, Y.5
  • 38
    • 34548515516 scopus 로고    scopus 로고
    • Acetaminophen safety and hepatotoxicity-where do we go from here?
    • Amar, P.J.; Schiff, E.R. Acetaminophen safety and hepatotoxicity-where do we go from here? Expert Opin. Drug Saf. 2007, 6, 341-355.
    • (2007) Expert Opin. Drug Saf , vol.6 , pp. 341-355
    • Amar, P.J.1    Schiff, E.R.2
  • 39
    • 0027788006 scopus 로고
    • Paracetamol (acetaminophen) poisoning
    • Thomas, S.H.L. Paracetamol (acetaminophen) poisoning. Pharmacol. Therapeut. 1993, 60, 91-120.
    • (1993) Pharmacol. Therapeut , vol.60 , pp. 91-120
    • Thomas, S.H.L.1
  • 40
    • 7544222053 scopus 로고    scopus 로고
    • Acetaminophen-induced hepatotoxicity: Role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition
    • DOI 10.1081/DMR-200033494
    • Hinson, J.A.; Reid, A.B.; McCullough, S.S.; James, L.P. Acetaminophen-induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition. Drug Metab. Rev. 2004, 36, 805-822. (Pubitemid 39453075)
    • (2004) Drug Metabolism Reviews , vol.36 , Issue.3-4 , pp. 805-822
    • Hinson, J.A.1    Reid, A.B.2    McCullough, S.S.3    James, L.P.4
  • 41
    • 40049104518 scopus 로고    scopus 로고
    • 4-hydroxynonenal-protein adducts: A reliable biomarker of lipid oxidation in liver diseases
    • Poli, G.; Biasi, F.; Leonarduzzei, G. 4-hydroxynonenal-protein adducts: A reliable biomarker of lipid oxidation in liver diseases. Mol. Asp. Med. 2009, 29, 67-71.
    • (2009) Mol. Asp. Med , vol.29 , pp. 67-71
    • Poli, G.1    Biasi, F.2    Leonarduzzei, G.3
  • 43
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer, H.; Schaur, R.J.; Zollner, H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 1991, 11, 81-128. (Pubitemid 121003917)
    • (1991) Free Radical Biology and Medicine , vol.11 , Issue.1 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 44
    • 18344385579 scopus 로고    scopus 로고
    • Nutritional dietary and postprandial oxidative stress
    • Sies, H.; Stahl, W.; Sevanian, A. Nutritional, dietary and postprandial oxidative stress. J. Nutr. 2005, 135, 969-972.
    • (2005) J. Nutr , vol.135 , pp. 969-972
    • Sies, H.1    Stahl, W.2    Sevanian, A.3
  • 45
    • 14644442283 scopus 로고    scopus 로고
    • Oxygen, oxidative stress, hypoxia, and heart failure
    • DOI 10.1172/JCI200524408
    • Giordano, F.J. Oxygen, oxidative stress, hypoxia, and heart failure. J. Clin. Invest. 2005, 115, 500-508. (Pubitemid 40322219)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.3 , pp. 500-508
    • Giordano, F.J.1
  • 47
    • 0043135016 scopus 로고    scopus 로고
    • The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity
    • DOI 10.1016/S0378-4274(03)00239-X
    • Jaeschke, H.; Knight, T.R.; Bajt, M.L. The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity. Toxicol. Lett. 2003, 144, 279-288. (Pubitemid 36966712)
    • (2003) Toxicology Letters , vol.144 , Issue.3 , pp. 279-288
    • Jaeschke, H.1    Knight, T.R.2    Bajt, M.L.3
  • 49
    • 0036804710 scopus 로고    scopus 로고
    • Free radicals, antioxidants and nutrition
    • Fang, Y.Z.; Yang, S.; Wu, G. Free radicals, antioxidants and nutrition. Nutrition 2002, 18, 872-879.
    • (2002) Nutrition , vol.18 , pp. 872-879
    • Fang, Y.Z.1    Yang, S.2    Wu, G.3
  • 50
    • 26044457028 scopus 로고    scopus 로고
    • Protective role of Vitamin E pre-treatment on N-nitrosodiethylamine induced oxidative stress in rat liver
    • DOI 10.1016/j.cbi.2005.08.001, PII S0009279705001857
    • Bansal, A.K.; Bansal, M.; Soni, G.; Bhatnagar, D. Protective role of Vitamin E pre-treatment on N-nitrosodiethylamine induced oxidative stress in rat liver. Chem. Biol. Interact. 2005, 156, 101-111. (Pubitemid 41406233)
    • (2005) Chemico-Biological Interactions , vol.156 , Issue.2-3 , pp. 101-111
    • Bansal, A.K.1    Bansal, M.2    Soni, G.3    Bhatnagar, D.4
  • 51
    • 77958557354 scopus 로고    scopus 로고
    • Effects of olive oil and its fractions on oxidative stress and the liver's fatty acid composition in 2,4-Dichlorophenoxyacetic acid-treated rats
    • Nakbi, A.; Tayeb, W.; Grissa, A.; Issaoui, M.; Dabbou, S.; Chargui, I.; Ellouz, M.; Miled, A.; Hammami, M. Effects of olive oil and its fractions on oxidative stress and the liver's fatty acid composition in 2,4- Dichlorophenoxyacetic acid-treated rats. Nutr. Metab. 2010, 7, 80.
    • (2010) Nutr. Metab , vol.7 , pp. 80
    • Nakbi, A.1    Tayeb, W.2    Grissa, A.3    Issaoui, M.4    Dabbou, S.5    Chargui, I.6    Ellouz, M.7    Miled, A.8    Hammami, M.9
  • 52
    • 17844371341 scopus 로고    scopus 로고
    • Oral or intravenous N-acetylcysteine for acetaminophen poisoning?
    • DOI 10.1016/j.annemergmed.2004.09.028, PII S0196064404014933
    • Prescott, L. Oral or intravenous N-acetylcysteine for acetaminophen poisoning? Ann. Emerg. Med. 2005, 5, 409-413. (Pubitemid 43181008)
    • (2005) Annals of Emergency Medicine , vol.45 , Issue.4 , pp. 409-413
    • Prescott, L.1
  • 54
    • 0027939613 scopus 로고
    • Nutrition and health aspects of free radicals and antioxidants
    • DOI 10.1016/0278-6915(94)90011-6
    • Aruoma, O.I. Nutrition and health aspects of free radicals and antioxidants. Food Chem. Toxicol. 1994, 32, 671-683. (Pubitemid 24248003)
    • (1994) Food and Chemical Toxicology , vol.32 , Issue.7 , pp. 671-683
    • Aruoma, O.I.1
  • 55
    • 84859708101 scopus 로고    scopus 로고
    • The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation
    • McGill, M.R.; Sharpe, M.R.; Williams, C.D.; Taha, M.; Curry, S.C.; Jaeschke, H. The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation. J. Clin. Invest. 2012, 122, 1574-1583.
    • (2012) J. Clin. Invest , vol.122 , pp. 1574-1583
    • McGill, M.R.1    Sharpe, M.R.2    Williams, C.D.3    Taha, M.4    Curry, S.C.5    Jaeschke, H.6
  • 57
    • 0036227896 scopus 로고    scopus 로고
    • Nutritional components modify metal absorption, toxic response and chelation therapy
    • DOI 10.1080/13590840220123361
    • Flora, S.J.S. Nutritional components modify metal absorption, toxic response and chelation therapy. J. Nutr. Environ. Med. 2002, 12, 53-67. (Pubitemid 34327132)
    • (2002) Journal of Nutritional and Environmental Medicine , vol.12 , Issue.1 , pp. 53-67
    • Flora, S.J.S.1
  • 58
    • 34547118377 scopus 로고    scopus 로고
    • A toxicologist guide to the diagnostic interpretation of hepatic biochemical parameters
    • DOI 10.1016/j.fct.2007.06.007, PII S0278691507001883
    • Ramaiah, S.K. A toxicologist guide to the diagnostic interpretation of hepatic biochemical parameters. Food Chem. Toxicol. 2007, 45, 1551-1557. (Pubitemid 47103335)
    • (2007) Food and Chemical Toxicology , vol.45 , Issue.9 , pp. 1551-1557
    • Ramaiah, S.K.1
  • 59
    • 60849083793 scopus 로고    scopus 로고
    • Protective effects of Coriandrum sativum extracts on carbon tetrachloride-induced hepatotoxicity in rats
    • Sreelatha, S.; Padma, P.R.; Umadevi, M. Protective effects of Coriandrum sativum extracts on carbon tetrachloride-induced hepatotoxicity in rats. Food Chem. Toxicol. 2009, 47, 702-708.
    • (2009) Food Chem. Toxicol , vol.47 , pp. 702-708
    • Sreelatha, S.1    Padma, P.R.2    Umadevi, M.3
  • 60
    • 36849054536 scopus 로고    scopus 로고
    • Protective effects of Pycnogenol® on carbon tetrachloride-induced hepatotoxicity in Sprague-Dawley rats
    • DOI 10.1016/j.fct.2007.08.016, PII S0278691507003067
    • Yang, Y.S.; Ahn, T.H.; Lee, J.C.; Moon, C.J.; Kim, S.H.; Jun, W.; Park, S.C.; Kim, H.C.; Kim, J.C. Protective effects of Pycnogenol on carbon tetrachloride-induced hepatotoxicity in Sprague-Dawley rats. Food Chem. Toxicol. 2008, 46, 380-387. (Pubitemid 350235783)
    • (2008) Food and Chemical Toxicology , vol.46 , Issue.1 , pp. 380-387
    • Yang, Y.-S.1    Ahn, T.-H.2    Lee, J.-C.3    Moon, C.-J.4    Kim, S.-H.5    Jun, W.6    Park, S.-C.7    Kim, H.-C.8    Kim, J.-C.9
  • 61
    • 37549052936 scopus 로고    scopus 로고
    • Comparison of S-adenosyl-l-methionine (SAMe) and N-acetylcysteine (NAC) protective effects on hepatic damage when administered after acetaminophen overdose
    • DOI 10.1016/j.tox.2007.10.027, PII S0300483X07007408
    • Terneus, M.V.; Brown, J.M.; Carpenter, A.B.; Valentovic, M.A. Comparison of S-adenosyl-Lmethionine (SAMe) and N-acetylcysteine (NAC) protective effects on hepatic damage when administered after acetaminophen overdose. Toxicology 2008, 244, 25-34. (Pubitemid 50009668)
    • (2008) Toxicology , vol.244 , Issue.1 , pp. 25-34
    • Terneus, M.V.1    Brown, J.M.2    Carpenter, A.B.3    Valentovic, M.A.4
  • 62
    • 33646582005 scopus 로고    scopus 로고
    • Antioxidant activities of aqueous extracts of selected plants
    • DOI 10.1016/j.foodchem.2005.07.058, PII S0308814605007612
    • Wong, S.P.; Leong, L.P.; Koh, J.H.W. Antioxidant activities of aqueous extracts of selected plants. Food Chem. 2006, 99, 775-783. (Pubitemid 43729561)
    • (2006) Food Chemistry , vol.99 , Issue.4 , pp. 775-783
    • Wong, S.P.1    Leong, L.P.2    William Koh, J.H.3
  • 63
    • 0029066426 scopus 로고
    • Isolation of xanthophylls from Taiwanese orange peels and their effects on the oxidation stability of soybean oil
    • Yen, W.J.; Chen, B.H. Isolation of xanthophylls from Taiwanese orange peels and their effects on the oxidation stability of soybean oil. Food Chem. 1995, 53, 417-425.
    • (1995) Food Chem , vol.53 , pp. 417-425
    • Yen, W.J.1    Chen, B.H.2
  • 64
    • 34447518702 scopus 로고    scopus 로고
    • Antioxidant activity and phenolic compounds in 32 selected herbs
    • DOI 10.1016/j.foodchem.2007.04.038, PII S0308814607003974
    • Wojdylo, A.; Oszmianski, J.; Czemerys, R. Antioxidant activity and phenolic compounds in 32 selected herbs. Food Chem. 2007, 105, 940-949. (Pubitemid 47079088)
    • (2007) Food Chemistry , vol.105 , Issue.3 , pp. 940-949
    • Wojdylo, A.1    Oszmianski, J.2    Czemerys, R.3
  • 65
    • 0030586361 scopus 로고    scopus 로고
    • The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": The FRAP assay
    • Benzie, I.F.; Strain, J.J. The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": The FRAP assay. Anal. Biochem. 1996, 239, 70-76.
    • (1996) Anal. Biochem , vol.239 , pp. 70-76
    • Benzie, I.F.1    Strain, J.J.2
  • 67
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72, 248-254.
    • (1976) Anal. Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 68
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • DOI 10.1016/0003-2697(79)90738-3
    • Onkawa, H.; Ohishi, N.; Yagi, K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 1979, 95, 351-358. (Pubitemid 9194347)
    • (1979) Analytical Biochemistry , vol.95 , Issue.2 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 69
    • 3042934967 scopus 로고
    • Tissue sulfhydryl groups
    • Ellman, G.L. Tissue Sulfhydryl Groups. Arch. Biochem. Biophys. 1959, 82, 70-77.
    • (1959) Arch. Biochem. Biophys , vol.82 , pp. 70-77
    • Ellman, G.L.1
  • 71
    • 0015353270 scopus 로고
    • Colorimetric assay of catalase
    • Sinha, A.K. Colorimetric assay of catalase. Anal. Biochem. 1972, 47, 389-394.
    • (1972) Anal. Biochem , vol.47 , pp. 389-394
    • Sinha, A.K.1


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