Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C

Journal of Biological Chemistry

Volumn 279, Issue 24, 2004, Pages 25813-25822

  Singh, Shivendra V ^a   Herman Antosiewicz, Anna ^a   Singh, Ajita V ^a   Lew, Karen L ^a   Srivastava, Sanjay K ^a   Kamath, Ravindra ^b   Brown, Kevin D ^c   Zhang, Lin ^a   Baskaran, Rajasekaran ^b  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DNA; ENZYMES; RNA; TUMORS;

CANCER CELLS; CELL CYCLE; PHOSPHORYLATION;

BIOCHEMISTRY;

ATM PROTEIN; CASPASE 8; CASPASE 9; CELL CYCLE PROTEIN; CHECKPOINT KINASE 2; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; HISTONE H2A; ISOTHIOCYANIC ACID; LACTACYSTIN; PROTEIN 14 3 3; PROTEIN 14 3 3BETA; PROTEIN CDC25B; PROTEIN CDC25C; REACTIVE OXYGEN METABOLITE; SERINE; SMALL INTERFERING RNA; SULFORAPHANE; TYROSINE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CDC25C PROTEIN; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE PHOSPHATASE; SULFORAFAN; THIOCYANIC ACID DERIVATIVE;

APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CELL DIVISION; CELL NUCLEUS; CELL PROLIFERATION; CELL PROTECTION; COLON CANCER; CONTROLLED STUDY; CYTOPLASM; DNA DAMAGE; DNA STRAND BREAKAGE; ENZYME ACTIVATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; ACTIVE TRANSPORT; CELL CULTURE; DRUG EFFECT; METABOLISM; MITOSIS; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN TRANSPORT;

ATAXIA; ATAXIA TELANGIECTASIA;

ACTIVE TRANSPORT, CELL NUCLEUS; ANTICARCINOGENIC AGENTS; CDC2 PROTEIN KINASE; CDC25 PHOSPHATASE; CELL CYCLE PROTEINS; CYTOPLASM; DNA DAMAGE; G2 PHASE; HUMANS; MITOSIS; PHOSPHORYLATION; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; THIOCYANATES; TUMOR CELLS, CULTURED;

EID: 2942614713     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M313538200     Document Type: Article

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