-
1
-
-
57349119169
-
Plumbagin-induced apoptosis of human breast cancer cells is mediated by inactivation of NF-kappaB and Bcl-2
-
Ahmad A, Banerjee S, Wang Z, et al (2008). Plumbagin-induced apoptosis of human breast cancer cells is mediated by inactivation of NF-kappaB and Bcl-2. J Cell Biochem, 105, 1461-71.
-
(2008)
J Cell Biochem
, vol.105
, pp. 1461-1471
-
-
Ahmad, A.1
Banerjee, S.2
Wang, Z.3
-
2
-
-
55349147671
-
Plumbagin, a medicinal plant-derived naphthoquinone, is a novel inhibitor of the growth and invasion of hormone - refractory prostate cancer
-
Aziz MH, Dreckschmidt NE, Verma AK (2008). Plumbagin, a medicinal plant-derived naphthoquinone, is a novel inhibitor of the growth and invasion of hormone - refractory prostate cancer. Cancer Res, 68, 9024-32.
-
(2008)
Cancer Res
, vol.68
, pp. 9024-9032
-
-
Aziz, M.H.1
Dreckschmidt, N.E.2
Verma, A.K.3
-
3
-
-
0029969860
-
Arsenic induces oxidant stress and NF-KB activation in cultured aortic endothelial cells
-
Barchowsky A, Dudek EJ, Treadwell MD, et al (1996). Arsenic induces oxidant stress and NF-KB activation in cultured aortic endothelial cells. Free Radic Biol Med, 21, 783-90.
-
(1996)
Free Radic Biol Med
, vol.21
, pp. 783-790
-
-
Barchowsky, A.1
Dudek, E.J.2
Treadwell, M.D.3
-
4
-
-
58049202263
-
Cytotoxicity Mechanism of Two Naphthoquinones (Menadione and Plumbagin) in Saccharomyces cerevisiae
-
Castro FA, Mariani D, Panek AD, et al (2008). Cytotoxicity Mechanism of Two Naphthoquinones (Menadione and Plumbagin) in Saccharomyces cerevisiae. PLoS One, 3, e3999.
-
(2008)
PLoS One
, vol.3
-
-
Castro, F.A.1
Mariani, D.2
Panek, A.D.3
-
5
-
-
55249099620
-
Hepatitis C virus infection induces apoptosis through a Bax-triggered, mitochondrion-mediated, caspase 3-dependent pathway
-
Deng L, Adachi T, Kitayama K, et al (2008). Hepatitis C virus infection induces apoptosis through a Bax-triggered, mitochondrion-mediated, caspase 3-dependent pathway. J Virol, 82, 10375-85.
-
(2008)
J Virol
, vol.82
, pp. 10375-10385
-
-
Deng, L.1
Adachi, T.2
Kitayama, K.3
-
6
-
-
11144322792
-
Inhibition of Nox- 4 activity by plumbagin, a plant-derived bioactive naphthoquinone
-
Ding YX, Chen ZJ, Liu S, et al (2005). Inhibition of Nox- 4 activity by plumbagin, a plant-derived bioactive naphthoquinone. J Pharm Pharmacol, 57, 111-6.
-
(2005)
J Pharm Pharmacol
, vol.57
, pp. 111-116
-
-
Ding, Y.X.1
Chen, Z.J.2
Liu, S.3
-
7
-
-
0016318441
-
Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium
-
Freedman VH, Shin SI (1974). Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium. Cell, 3, 355-9.
-
(1974)
Cell
, vol.3
, pp. 355-359
-
-
Freedman, V.H.1
Shin, S.I.2
-
8
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner MO (2000).The biochemistry of apoptosis. Nature, 407, 770-6.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
9
-
-
33745967219
-
Plumbagin (5-Hydroxy-2 -methyl- 1, 4- naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo
-
Hsu YL, Cho CY, Kuo PL, et al (2006). Plumbagin (5-Hydroxy-2 -methyl- 1, 4- naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo. J Pharmacol Exp Ther, 318, 484-94.
-
(2006)
J Pharmacol Exp Ther
, vol.318
, pp. 484-494
-
-
Hsu, Y.L.1
Cho, C.Y.2
Kuo, P.L.3
-
10
-
-
0026748993
-
Exogenous quinones directly inhibit the respiratory NADH dehydrogenase in Escherichia coli
-
Imlay J, Fridovich I (1992). Exogenous quinones directly inhibit the respiratory NADH dehydrogenase in Escherichia coli. Arch Biochem Biophys, 296, 337-46.
-
(1992)
Arch Biochem Biophys
, vol.296
, pp. 337-346
-
-
Imlay, J.1
Fridovich, I.2
-
11
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A, Siegel R, Ward E, et al (2009). Cancer statistics, 2009. CA Cancer J Clin, 59, 225-49.
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
12
-
-
84860341468
-
Plumbagin induces apoptosis in Her2-overexpressing breast cancer cells through the mitochondrial-mediated pathway
-
Kawiak A, Zawacka-Pankau J, Lojkowska E (2012). Plumbagin induces apoptosis in Her2-overexpressing breast cancer cells through the mitochondrial-mediated pathway. J Nat Prod, 75, 747-51.
-
(2012)
J Nat Prod
, vol.75
, pp. 747-751
-
-
Kawiak, A.1
Zawacka-pankau, J.2
Lojkowska, E.3
-
13
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin M (2006). Nuclear factor-kappaB in cancer development and progression. Nature, 441, 431-6.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
14
-
-
85008378165
-
Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells
-
Kuo PL, Hsu YL, Cho CY (2006). Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells. Mol Cancer Ther, 3, 209-21.
-
(2006)
Mol Cancer Ther
, vol.3
, pp. 209-221
-
-
Kuo, P.L.1
Hsu, Y.L.2
Cho, C.Y.3
-
15
-
-
39749123276
-
Apoptosis and necrosis: detection, discrimination and phagocytosis
-
Krysko DV, Vanden Berghe T, D'Herde K, et al (2008). Apoptosis and necrosis: detection, discrimination and phagocytosis. Methods, 44, 205-21.
-
(2008)
Methods
, vol.44
, pp. 205-221
-
-
Krysko, D.V.1
Vanden Berghe, T.2
D'herde, K.3
-
16
-
-
84863158729
-
Plumbagin inhibits cell growth and potentiates apoptosis in human gastric cancer cells in vitro through the NF-?B signaling pathway
-
Li J, Shen L, Lu FR, et al (2012). Plumbagin inhibits cell growth and potentiates apoptosis in human gastric cancer cells in vitro through the NF-?B signaling pathway. Acta Pharmacol Sin, 33, 242-9.
-
(2012)
Acta Pharmacol Sin
, vol.33
, pp. 242-249
-
-
Li, J.1
Shen, L.2
Lu, F.R.3
-
17
-
-
80052167167
-
Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4
-
Manu KA, Shanmugam MK, Rajendran P, et al (2011). Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4. Mol Cancer, 10, 107.
-
(2011)
Mol Cancer
, vol.10
, pp. 107
-
-
Manu, K.A.1
Shanmugam, M.K.2
Rajendran, P.3
-
18
-
-
14044261093
-
Tumor necrosis factor, cancer and anticancer therapy
-
Mocellin S, Rossi CR, Pilati P, et al (2005). Tumor necrosis factor, cancer and anticancer therapy. Cytokine Growth Factor Rev, 16, 35-53.
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 35-53
-
-
Mocellin, S.1
Rossi, C.R.2
Pilati, P.3
-
19
-
-
11144241343
-
Antimycobacterial constituents from juniperus procera, ferula communis and plumbago zeylanica and their in vitro synergistic activity with isonicotinic acid hydrazide
-
Mossa JS, El-Feraly FS, Muhammad I (2004). Antimycobacterial constituents from juniperus procera, ferula communis and plumbago zeylanica and their in vitro synergistic activity with isonicotinic acid hydrazide. Phytother Res, 18, 934-7.
-
(2004)
Phytother Res
, vol.18
, pp. 934-937
-
-
Mossa, J.S.1
El-feraly, F.S.2
Muhammad, I.3
-
20
-
-
38349057302
-
Radiosensitizing effects of plumbagin in cervical cancer cells is through modulation of apoptotic pathway
-
Nair S, Nair RR, Srinivas P, et al (2008). Radiosensitizing effects of plumbagin in cervical cancer cells is through modulation of apoptotic pathway. Mol Carcino, 47, 22-33.
-
(2008)
Mol Carcino
, vol.47
, pp. 22-33
-
-
Nair, S.1
Nair, R.R.2
Srinivas, P.3
-
21
-
-
0033538340
-
Differential IkappaB kinase activation and IkappaBalpha degradation by interleukin-1beta and tumor necrosis factor-alpha in human U937 monocytic cells. Evidence for additional regulatory steps in kappaB-dependent transcription
-
Nasuhara Y, Adcock IM, Catley M, et al (1999). Differential IkappaB kinase activation and IkappaBalpha degradation by interleukin-1beta and tumor necrosis factor-alpha in human U937 monocytic cells. Evidence for additional regulatory steps in kappaB-dependent transcription. J Biol Chem, 274, 19965-72.
-
(1999)
J Biol Chem
, vol.274
, pp. 19965-19972
-
-
Nasuhara, Y.1
Adcock, I.M.2
Catley, M.3
-
22
-
-
0025997412
-
Menadione-induced DNA damage in a human tumor cell line
-
Ngo EO, Sun TP, Chang JY, et al (1991). Menadione-induced DNA damage in a human tumor cell line. Biochem Pharmacol, 42, 1961-8.
-
(1991)
Biochem Pharmacol
, vol.42
, pp. 1961-1968
-
-
Ngo, E.O.1
Sun, T.P.2
Chang, J.Y.3
-
23
-
-
0024584484
-
Effects of sodium ascorbate (vitamin C) and 2-methyl-1, 4-naphthoquinone (vitamin K3) treatment on human tumor cell growth in vitro. I. Synergism of combined vitamin C and K3 action
-
Noto V, Taper HS, Jiang YH, et al (1989). Effects of sodium ascorbate (vitamin C) and 2-methyl-1, 4-naphthoquinone (vitamin K3) treatment on human tumor cell growth in vitro. I. Synergism of combined vitamin C and K3 action. Cancer, 63, 901-6.
-
(1989)
Cancer
, vol.63
, pp. 901-906
-
-
Noto, V.1
Taper, H.S.2
Jiang, Y.H.3
-
24
-
-
33847276516
-
Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatin plus vinorelbine for advanced non-small-cell lung cancer: Four- Arm Cooperative Study in Japan
-
Ohe Y, Ohashi Y, Kubota K, et al (2007).Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatin plus vinorelbine for advanced non-small-cell lung cancer: Four- Arm Cooperative Study in Japan. Ann Oncol, 18, 317-23.
-
(2007)
Ann Oncol
, vol.18
, pp. 317-323
-
-
Ohe, Y.1
Ohashi, Y.2
Kubota, K.3
-
25
-
-
49549083508
-
Plumbagin-induced apoptosis in human prostate cancer cells is associated with modulation of cellular redox status and generation of reactive oxygen species
-
Powolny AA, Singh SV (2008). Plumbagin-induced apoptosis in human prostate cancer cells is associated with modulation of cellular redox status and generation of reactive oxygen species. Pharm Res, 25, 2171-80.
-
(2008)
Pharm Res
, vol.25
, pp. 2171-2180
-
-
Powolny, A.A.1
Singh, S.V.2
-
26
-
-
33144474858
-
Should chemotherapy combinations for advanced non-small cell lung cancer be platinum-based? A meta-analysis of phase III randomized trials
-
Pujol JL, Barlesi F, and Daures JP (2006). Should chemotherapy combinations for advanced non-small cell lung cancer be platinum-based? A meta-analysis of phase III randomized trials. Lung Cancer, 51, 335-45.
-
(2006)
Lung Cancer
, vol.51
, pp. 335-345
-
-
Pujol, J.L.1
Barlesi, F.2
Daures, J.P.3
-
27
-
-
84861112895
-
Neuroprotection by the soy isoflavone, genistein, via inhibition of mitochondriadependent apoptosis pathways and reactive oxygen induced- NF-?B activation in a cerebral ischemia mouse model
-
Qian Y, Guan T, Huang M, et al (2012). Neuroprotection by the soy isoflavone, genistein, via inhibition of mitochondriadependent apoptosis pathways and reactive oxygen induced- NF-?B activation in a cerebral ischemia mouse model. Neurochem Int, 60, 759-67.
-
(2012)
Neurochem Int
, vol.60
, pp. 759-767
-
-
Qian, Y.1
Guan, T.2
Huang, M.3
-
28
-
-
33745220306
-
Plumbagin (5-Hydroxy-2-methyl-1, 4-naphthoquinone) suppresses NF-?B activation and NF-?B-regulated gene products through modulation of p65 and I?B kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents
-
Sandur SK, Ichikawa H, Sethi G, et al (2006). Plumbagin (5-Hydroxy-2-methyl-1, 4-naphthoquinone) suppresses NF-?B activation and NF-?B-regulated gene products through modulation of p65 and I?B kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents. J Biol Chem, 281, 17023-33.
-
(2006)
J Biol Chem
, vol.281
, pp. 17023-17033
-
-
Sandur, S.K.1
Ichikawa, H.2
Sethi, G.3
-
29
-
-
75949115154
-
Plumbagin inhibits TPA-induced MMP-2 and u-PA expressions by reducing binding activities of NF-?B and AP-1 via ERK signaling pathway in A549 human lung cancer cells
-
Shieh JM, Chiang TA, Chang WT, et al (2010). Plumbagin inhibits TPA-induced MMP-2 and u-PA expressions by reducing binding activities of NF-?B and AP-1 via ERK signaling pathway in A549 human lung cancer cells. Mol Cell Biochem, 335, 181-93.
-
(2010)
Mol Cell Biochem
, vol.335
, pp. 181-193
-
-
Shieh, J.M.1
Chiang, T.A.2
Chang, W.T.3
-
30
-
-
4043159799
-
Plumbagin induces reactive oxygen species, which mediate apoptosis in human cervical cancer cells
-
Srinivas P, Gopinath G, Banerji A, et al (2004). Plumbagin induces reactive oxygen species, which mediate apoptosis in human cervical cancer cells. Mol Carcinog, 40, 201-11.
-
(2004)
Mol Carcinog
, vol.40
, pp. 201-211
-
-
Srinivas, P.1
Gopinath, G.2
Banerji, A.3
-
31
-
-
41549142664
-
Estrogen-dependent cell signaling and apoptosis in BRCA1-blocked BG1 ovarian cancer cells in response to plumbagin and other chemotherapeutic agents
-
Thasni KA, Rakesh S, Rojini G, et al (2008). Estrogen-dependent cell signaling and apoptosis in BRCA1-blocked BG1 ovarian cancer cells in response to plumbagin and other chemotherapeutic agents. Ann Oncol, 19, 696-705.
-
(2008)
Ann Oncol
, vol.19
, pp. 696-705
-
-
Thasni, K.A.1
Rakesh, S.2
Rojini, G.3
-
32
-
-
37049005766
-
Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375
-
Wang CC, Chiang YM, Sung SC, et al (2008). Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells. Cancer Lett, 259, 82-98.
-
(2008)
S2 cells. Cancer Lett
, vol.259
, pp. 82-98
-
-
Wang, C.C.1
Chiang, Y.M.2
Sung, S.C.3
-
33
-
-
77950085770
-
Plumbagin induces ROS-mediated apoptosis in human promyelocytic leukemia cells in vivo
-
Xu KH, Lu DP (2010). Plumbagin induces ROS-mediated apoptosis in human promyelocytic leukemia cells in vivo. Leuk Res, 34, 658-65.
-
(2010)
Leuk Res
, vol.34
, pp. 658-665
-
-
Xu, K.H.1
Lu, D.P.2
|