Plumbagin, a plant derived natural agent inhibits the growth of pancreatic cancer cells in in vitro and in vivo via targeting EGFR, Stat3 and NF-κB signaling pathways

International Journal of Cancer

Volumn 131, Issue 9, 2012, Pages 2175-2186

  Hafeez, Bilal Bin ^a   Jamal, Mohammad Sarwar ^a   Fischer, Joseph W ^a   Mustafa, Ala ^a   Verma, Ajit Kumar ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

EGFR; NF B; plumbagin; Stat3

Indexed keywords

CYCLIN D1; DNA; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PLUMBAGIN; SERINE; STAT3 PROTEIN; SURVIVIN; TYROSINE; VASCULOTROPIN RECEPTOR;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL CULTURE; CELL VIABILITY; DNA BINDING; DOWNSTREAM PROCESSING; GENE TARGETING; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PANCREAS CANCER; PLUMBAGO ZEYLANICA; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SCID MOUSE; SIGNAL TRANSDUCTION; TUMOR VOLUME; XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN D1; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, SCID; NAPHTHOQUINONES; NF-KAPPA B; PANCREATIC NEOPLASMS; PHOSPHORYLATION; PLANT EXTRACTS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84865549508     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.27478     Document Type: Article

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