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Volumn 33, Issue 2, 2012, Pages 242-249

Plumbagin inhibits cell growth and potentiates apoptosis in human gastric cancer cells in vitro through the NF-B signaling pathway

Author keywords

anticancer drug; apoptosis; cisplatin; gastric carcinoma; NF B; plumbagin; TNF

Indexed keywords

CISPLATIN; I KAPPA B ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PLUMBAGIN; PROTEIN BCL 2; PROTEIN BCL XL; SYNAPTOTAGMIN I; VASCULOTROPIN; X LINKED INHIBITOR OF APOPTOSIS;

EID: 84863158729     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.152     Document Type: Article
Times cited : (54)

References (35)
  • 1
    • 67349150698 scopus 로고    scopus 로고
    • Targeting apoptosis as an approach for gastrointestinal cancer therapy
    • Qiao L, Wong BC. Targeting apoptosis as an approach for gastrointestinal cancer therapy. Drug Resist Update 2009; 12: 55-64.
    • (2009) Drug Resist Update , vol.12 , pp. 55-64
    • Qiao, L.1    Wong, B.C.2
  • 3
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh YJ. Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 2003; 3: 768-80.
    • (2003) Nat Rev Cancer , vol.3 , pp. 768-780
    • Surh, Y.J.1
  • 4
    • 41749109134 scopus 로고    scopus 로고
    • Clinical observation on trigonella foenum-graecum L total saponins in combinaiton with sul phanylureas in the treatment of type 2 diabetes mellitus
    • Lu FR, Shen L, Qin Y, Gao L, Li H, Dai Y. Clinical observation on trigonella foenum-graecum L total saponins in combinaiton with sul phanylureas in the treatment of type 2 diabetes mellitus. Chin J Integr Med 2008; 14: 56-60.
    • (2008) Chin J Integr Med , vol.14 , pp. 56-60
    • Lu, F.R.1    Shen, L.2    Qin, Y.3    Gao, L.4    Li, H.5    Dai, Y.6
  • 5
    • 55349147671 scopus 로고    scopus 로고
    • Plumbagin, a medicinal plant-derived naphthoquinone, is a novel inhibitor of the growth and invasion of hormone - Refractory prostate cancer
    • Aziz MH, Dreckschmidt NE, Verma AK. Plumbagin, a medicinal plant-derived naphthoquinone, is a novel inhibitor of the growth and invasion of hormone - refractory prostate cancer. Cancer Res 2008; 68: 9024-32.
    • (2008) Cancer Res , vol.68 , pp. 9024-9032
    • Aziz, M.H.1    Dreckschmidt, N.E.2    Verma, A.K.3
  • 6
    • 11144241343 scopus 로고    scopus 로고
    • Antimycobacterial constituents from Juniperus procera, Ferula communis and Plumbago zeylanica and their in vitro synergistic activity with isonicotinic acid hydrazide
    • DOI 10.1002/ptr.1420
    • Mossa JS, El-Feraly FS, Muhammad I. Antimycobacterial constituents from Juniperus procera, Ferula communis and Plumbago zeylanica and their in vitro synergistic activity with isonicotinic acid hydrazide. Phytother Res 2004; 18: 934-37. (Pubitemid 40052774)
    • (2004) Phytotherapy Research , vol.18 , Issue.11 , pp. 934-937
    • Mossa, J.S.1    El-Feraly, F.S.2    Muhammad, I.3
  • 8
    • 33846233374 scopus 로고    scopus 로고
    • 2-M arrest and auto-phagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells
    • 2-M arrest and auto-phagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells. Mol Cancer Ther 2006; 5: 3209-21.
    • (2006) Mol Cancer Ther , vol.5 , pp. 3209-3221
    • Kuo, P.L.1    Hsu, Y.L.2    Cho, C.Y.3
  • 9
    • 37049005766 scopus 로고    scopus 로고
    • Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells
    • DOI 10.1016/j.canlet.2007.10.005, PII S0304383507004727
    • Wang CC, Chiang YM, Sung SC, Hsu YL, Chang JK, Kuo PL. Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375. S2 cells. Cancer Lett 2008; 259: 82-98. (Pubitemid 350245420)
    • (2008) Cancer Letters , vol.259 , Issue.1 , pp. 82-98
    • Wang, C.C.C.1    Chiang, Y.-M.2    Sung, S.-C.3    Hsu, Y.-L.4    Chang, J.-K.5    Kuo, P.-L.6
  • 10
    • 75949115154 scopus 로고    scopus 로고
    • Plumbagin inhibits TPA-induced MMP-2 and u-PA expressions by reducing binding activities of NF-kappaB and AP-1 via ERK signaling pathway in A549 human lung cancer cells
    • Shieh JM, Chiang TA, Chang WT, Chao CH, Lee YC, Huang GY, et al. Plumbagin inhibits TPA-induced MMP-2 and u-PA expressions by reducing binding activities of NF-kappaB and AP-1 via ERK signaling pathway in A549 human lung cancer cells. Mol Cell Biochem 2010; 335: 181-93.
    • (2010) Mol Cell Biochem , vol.335 , pp. 181-193
    • Shieh, J.M.1    Chiang, T.A.2    Chang, W.T.3    Chao, C.H.4    Lee, Y.C.5    Huang, G.Y.6
  • 11
    • 33745220306 scopus 로고    scopus 로고
    • Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to poten tia-tion of apoptosis induced by cytokine and chemotherapeutic agents
    • Sandur SK, Ichikawa H, Sethi G, Ahn KS, Aggarwal BB. Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to poten tia-tion of apoptosis induced by cytokine and chemotherapeutic agents. J Biol Chem 2006; 281: 17023-33.
    • (2006) J Biol Chem , vol.281 , pp. 17023-33
    • Sandur, S.K.1    Ichikawa, H.2    Sethi, G.3    Ahn, K.S.4    Aggarwal, B.B.5
  • 13
    • 4544342570 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: The enemy within
    • Aggarwal BB. Nuclear factor-kappaB: the enemy within. Cancer Cell 2004; 6: 203-8.
    • (2004) Cancer Cell , vol.6 , pp. 203-208
    • Aggarwal, B.B.1
  • 14
    • 77957592789 scopus 로고    scopus 로고
    • Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals
    • Gupta SC, Kim JH, Prasad S, Aggarwal BB. Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals. Cancer Metast Rev 2010; 29: 405-34.
    • (2010) Cancer Metast Rev , vol.29 , pp. 405-434
    • Gupta, S.C.1    Kim, J.H.2    Prasad, S.3    Aggarwal, B.B.4
  • 17
    • 54049146611 scopus 로고    scopus 로고
    • Paeoniforin suppress NF-kappaB activa tion through modulation of i kappaB alpha and enhances 5-fluorouracil-induced apoptosis in human gastric carcinoma cells
    • Wu H, Li W, Wang T, Shu Y, Liu P. Paeoniforin suppress NF-kappaB activa tion through modulation of I kappaB alpha and enhances 5-fluorouracil-induced apoptosis in human gastric carcinoma cells. Bio med Pharmacother 2008; 62: 659-66.
    • (2008) Bio Med Pharmacother , vol.62 , pp. 659-666
    • Wu, H.1    Li, W.2    Wang, T.3    Shu, Y.4    Liu, P.5
  • 18
    • 77954959058 scopus 로고    scopus 로고
    • Wogonin potentiates the antitumor effects of low dose 5-fuorouracil against gastric cancer through induction of apoptosis by down-regulation of NF-kappaB and regulation of its metabolism
    • Zhao Q, Wang J, Zou MJ, Hu R, Zhao L, Qiang L, et al. Wogonin potentiates the antitumor effects of low dose 5-fuorouracil against gastric cancer through induction of apoptosis by down-regulation of NF-kappaB and regulation of its metabolism. Toxicol Lett 2010; 197: 201-10.
    • (2010) Toxicol Lett , vol.197 , pp. 201-210
    • Zhao, Q.1    Wang, J.2    Zou, M.J.3    Hu, R.4    Zhao, L.5    Qiang, L.6
  • 19
    • 71749104937 scopus 로고    scopus 로고
    • L-DOPA-induced neuro toxi-city is reduced by the activation of the PI3K signaling pathway
    • Park HH, Lee KY, Kim SH, Lee YJ, Koh SH. L-DOPA-induced neuro toxi-city is reduced by the activation of the PI3K signaling pathway. Toxicology 2009; 265: 80-6.
    • (2009) Toxicology , vol.265 , pp. 80-86
    • Park, H.H.1    Lee, K.Y.2    Kim, S.H.3    Lee, Y.J.4    Koh, S.H.5
  • 20
    • 78751616954 scopus 로고    scopus 로고
    • Silencing USP22 by asymmetric structure of interfering RNA inhibits proliferation and induces cell cycle arrest in bladder cancer cells
    • Lv L, Xiao XY, Gu ZH, Zeng FQ, Huang LQ, Jiang GS. Silencing USP22 by asymmetric structure of interfering RNA inhibits proliferation and induces cell cycle arrest in bladder cancer cells. Mol Cell Biochem 2011; 346: 11-21.
    • (2011) Mol Cell Biochem , vol.346 , pp. 11-21
    • Lv, L.1    Xiao, X.Y.2    Gu, Z.H.3    Zeng, F.Q.4    Huang, L.Q.5    Jiang, G.S.6
  • 21
    • 35349029248 scopus 로고    scopus 로고
    • Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-κB signaling pathway
    • DOI 10.1182/blood-2007-03-079616
    • Pandey MK, Sung B, Ahn KS, Kunnumakkara AB, Chaturvedi MM, Aggarwal BB. Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway. Blood 2007; 110: 3517-25. (Pubitemid 350159615)
    • (2007) Blood , vol.110 , Issue.10 , pp. 3517-3525
    • Pandey, M.K.1    Sung, B.2    Kwang, S.A.3    Kunnumakkara, A.B.4    Chaturvedi, M.M.5    Aggarwal, B.B.6
  • 22
    • 77950540096 scopus 로고    scopus 로고
    • Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor alpha by inhibiting NF-kappaB signaling pathway
    • Li C, Yang Z, Zhai C, Qiu W, Li D, Yi Z, et al. Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor alpha by inhibiting NF-kappaB signaling pathway. Mol Cancer 2010; 9: 73.
    • (2010) Mol Cancer , vol.9 , pp. 73
    • Li, C.1    Yang, Z.2    Zhai, C.3    Qiu, W.4    Li, D.5    Yi, Z.6
  • 25
    • 0037851769 scopus 로고    scopus 로고
    • IKKβ plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide
    • Yang F, Tang E, Guan K, Wang CY. IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide. J Immunol 2003; 170: 5630-5. (Pubitemid 36617854)
    • (2003) Journal of Immunology , vol.170 , Issue.11 , pp. 5630-5635
    • Yang, F.1    Tang, E.2    Guan, K.3    Wang, C.-Y.4
  • 26
    • 76249092901 scopus 로고    scopus 로고
    • Curcumin suppresses proliferation and invasion in human gastric cancer cells by downregulation of PAK1 activity and cyclin D1 expression
    • Cai XZ, Wang J, Li XD, Wang GL, Liu FN, Cheng MS, et al. Curcumin suppresses proliferation and invasion in human gastric cancer cells by downregulation of PAK1 activity and cyclin D1 expression. Cancer Biol Ther 2009; 8: 1360-8.
    • (2009) Cancer Biol Ther , vol.8 , pp. 1360-1368
    • Cai, X.Z.1    Wang, J.2    Li, X.D.3    Wang, G.L.4    Liu, F.N.5    Cheng, M.S.6
  • 27
    • 79952096698 scopus 로고    scopus 로고
    • Interaction of coagulation factors and tumor-associated macrophages mediates migration and invasion of gastric cancer
    • Ma YY, He XJ, Wang HJ, Xia YJ, Wang SL, Ye ZY, et al. Interaction of coagulation factors and tumor-associated macrophages mediates migration and invasion of gastric cancer. Cancer Sci 2010; 102: 336-42.
    • (2010) Cancer Sci , vol.102 , pp. 336-342
    • Ma, Y.Y.1    He, X.J.2    Wang, H.J.3    Xia, Y.J.4    Wang, S.L.5    Ye, Z.Y.6
  • 28
    • 51049106423 scopus 로고    scopus 로고
    • Aberrant NF-kappaB activity is critical in focal necrosis formation of human glioblastoma by regulation of the expression of tissue factor
    • Xie TX, Aldape KD, Gong W, Kanzawa T, Suki D, Kondo S, et al. Aberrant NF-kappaB activity is critical in focal necrosis formation of human glioblastoma by regulation of the expression of tissue factor. Int J Oncol 2008; 33: 5-15.
    • (2008) Int J Oncol , vol.33 , pp. 5-15
    • Xie, T.X.1    Aldape, K.D.2    Gong, W.3    Kanzawa, T.4    Suki, D.5    Kondo, S.6
  • 29
    • 3042523535 scopus 로고    scopus 로고
    • Activation of transcription factor NF-κB requiries ELKS, an IκB kinase regulatory subunit
    • DOI 10.1126/science.1098387
    • Ducut Sigala JL, Bottero V, Young DB, Shevchenko A, Mercurio F, Verma IM. Activation of transcription factor NF-kappaB requires ELKS, an IkappaB kinase regulatory subunit. Science 2004; 304: 1963-7. (Pubitemid 38822188)
    • (2004) Science , vol.304 , Issue.5679 , pp. 1963-1967
    • Sigala, J.L.D.1    Bottero, V.2    Young, D.B.3    Shevchenko, A.4    Mercurio, F.5    Verma, I.M.6
  • 30
    • 48549105216 scopus 로고    scopus 로고
    • Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis
    • Pandey MK, Sung B, Kunnumakkara AB, Sethi G, Chaturvedi MM, Aggarwal BB. Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis. Cancer Res 2008; 68: 5370-9.
    • (2008) Cancer Res , vol.68 , pp. 5370-5379
    • Pandey, M.K.1    Sung, B.2    Kunnumakkara, A.B.3    Sethi, G.4    Chaturvedi, M.M.5    Aggarwal, B.B.6
  • 31
    • 74949124948 scopus 로고    scopus 로고
    • Berbamine, a novel nuclear factor kappaB inhibitor, inhibits growth and induces apoptosis in human myeloma cells
    • Liang Y, Xu RZ, Zhang L, Zhao XY. Berbamine, a novel nuclear factor kappaB inhibitor, inhibits growth and induces apoptosis in human myeloma cells. Acta Pharmacol Sin 2009; 12: 1659-65.
    • (2009) Acta Pharmacol Sin , vol.12 , pp. 1659-1665
    • Liang, Y.1    Xu, R.Z.2    Zhang, L.3    Zhao, X.Y.4
  • 32
    • 30044446136 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IκBα kinase and Akt activation
    • DOI 10.1124/mol.105.017400
    • Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, Aggarwal BB. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation. Mol Pharmacol 2006; 69: 195-206. (Pubitemid 43048906)
    • (2006) Molecular Pharmacology , vol.69 , Issue.1 , pp. 195-206
    • Aggarwal, S.1    Ichikawa, H.2    Takada, Y.3    Sandur, S.K.4    Shishodia, S.5    Aggarwal, B.B.6
  • 33
    • 34347221946 scopus 로고    scopus 로고
    • Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP-1 and NFκB transcription factors
    • DOI 10.1111/j.1471-4159.2007.04633.x
    • Dhandapani KM, Mahesh VB, Brann DW. Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP-1 and NFkappaB transcription factors. J Neurochem 2007; 102: 522-38. (Pubitemid 47000605)
    • (2007) Journal of Neurochemistry , vol.102 , Issue.2 , pp. 522-538
    • Dhandapani, K.M.1    Mahesh, V.B.2    Brann, D.W.3
  • 34
    • 33847252433 scopus 로고    scopus 로고
    • Sensitization of TNF-induced cytotoxicity in lung cancer cells by concurrent suppression of the NF-κB and Akt pathways
    • DOI 10.1016/j.bbrc.2007.02.030, PII S0006291X07003130
    • Wang X, Chen W, Lin Y. Sensitization of TNF-induced cytotoxicity in lung cancer cells by concurrent suppression of the NF-kappaB and Akt pathways. Biochem Biophys Res Commun 2007; 355: 807-12. (Pubitemid 46330225)
    • (2007) Biochemical and Biophysical Research Communications , vol.355 , Issue.3 , pp. 807-812
    • Wang, X.1    Chen, W.2    Lin, Y.3
  • 35
    • 0032577708 scopus 로고    scopus 로고
    • Constitutive activation of NF-κB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells: Autocrine role of tumor necrosis factor and reactive oxygen intermediates
    • DOI 10.1074/jbc.273.22.14008
    • Giri DK, Aggarwal BB. Constitutive activation of NF-kappaB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. Autocrine role of tumor necrosis factor and reactive oxygen inter mediates. J Biol Chem 1998; 273: 14008-14. (Pubitemid 28268457)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.22 , pp. 14008-14014
    • Giri, D.K.1    Aggarwal, B.B.2


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