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Volumn 69, Issue , 2014, Pages 481-511

Salvinorin A analogs and other kappa-opioid receptor compounds as treatments for cocaine abuse

Author keywords

Addiction; Drug abuse; Kappa opioid receptor; Salvia divinorum; Salvinorin A

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; COCAINE; DITERPENE; DOPAMINE; DYNORPHIN; ENDORPHIN; ETHOXYMETHYL ETHER SALVINORIN B; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; METHOXYMETHYL ETHER SALVINORIN B; N METHYL N [7 (1 PYRROLIDINYL) 1 OXASPIRO[4.5]DEC 8 YL]BENZENEACETAMIDE; OPIATE; OPIATE RECEPTOR; PRODYNORPHIN; SALVINORIN A; UNCLASSIFIED DRUG;

EID: 84893194258     PISSN: 10543589     EISSN: 15578925     Source Type: Book Series    
DOI: 10.1016/B978-0-12-420118-7.00012-3     Document Type: Chapter
Times cited : (52)

References (167)
  • 1
    • 0035869777 scopus 로고    scopus 로고
    • Modulation of pre- and postsynaptic dopamine D2 receptor function by the selective kappa-opioid receptor agonist U69593
    • Acri J.B., Thompson A.C., Shippenberg T. Modulation of pre- and postsynaptic dopamine D2 receptor function by the selective kappa-opioid receptor agonist U69593. Synapse 2001, 39(4):343-350.
    • (2001) Synapse , vol.39 , Issue.4 , pp. 343-350
    • Acri, J.B.1    Thompson, A.C.2    Shippenberg, T.3
  • 2
    • 0028987257 scopus 로고
    • Kappa-opioid receptor-transfected cell-lines-Modulation of adenylyl-cyclase activity following acute and chronic opioid treatments
    • Avidorreiss T., Zippel R., Levy R., Saya D., Ezra V., Barg J., et al. Kappa-opioid receptor-transfected cell-lines-Modulation of adenylyl-cyclase activity following acute and chronic opioid treatments. FEBS Letters 1995, 361(1):70-74.
    • (1995) FEBS Letters , vol.361 , Issue.1 , pp. 70-74
    • Avidorreiss, T.1    Zippel, R.2    Levy, R.3    Saya, D.4    Ezra, V.5    Barg, J.6
  • 3
    • 62449248169 scopus 로고    scopus 로고
    • Comparison of the discriminative stimulus effects of salvinorin A and its derivatives to U69,593 and U50,488 in rats
    • Baker L.E., Panos J.J., Killinger B.A., Peet M.M., Bell L.M., Haliw L.A., et al. Comparison of the discriminative stimulus effects of salvinorin A and its derivatives to U69,593 and U50,488 in rats. Psychopharmacology 2009, 203(2):203-211.
    • (2009) Psychopharmacology , vol.203 , Issue.2 , pp. 203-211
    • Baker, L.E.1    Panos, J.J.2    Killinger, B.A.3    Peet, M.M.4    Bell, L.M.5    Haliw, L.A.6
  • 4
    • 77953286297 scopus 로고    scopus 로고
    • Effectiveness of analogs of the kappa opioid receptor antagonist (3R)-7-hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) to reduce U50,488-induced diuresis and stress-induced cocaine reinstatement in rats
    • Beardsley P.M., Pollard G.T., Howard J.L., Carroll F.I. Effectiveness of analogs of the kappa opioid receptor antagonist (3R)-7-hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) to reduce U50,488-induced diuresis and stress-induced cocaine reinstatement in rats. Psychopharmacology 2010, 210(2):189-198.
    • (2010) Psychopharmacology , vol.210 , Issue.2 , pp. 189-198
    • Beardsley, P.M.1    Pollard, G.T.2    Howard, J.L.3    Carroll, F.I.4
  • 6
    • 23044509956 scopus 로고    scopus 로고
    • Mu and kappa opioid receptors activate ERK/MAPK via different protein kinase c isoforms and secondary messengers in astrocytes
    • Belcheva M.M., Clark A.L., Haas P.D., Serna J.S., Hahn J.W., Kiss A., et al. mu and kappa opioid receptors activate ERK/MAPK via different protein kinase c isoforms and secondary messengers in astrocytes. Journal of Biological Chemistry 2005, 280(30):27662-27669.
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.30 , pp. 27662-27669
    • Belcheva, M.M.1    Clark, A.L.2    Haas, P.D.3    Serna, J.S.4    Hahn, J.W.5    Kiss, A.6
  • 7
    • 0024855153 scopus 로고
    • 3H]dopamine uptake is similar in both the rat striatum and nucleus accumbens
    • 3H]dopamine uptake is similar in both the rat striatum and nucleus accumbens. European Journal of Pharmacology 1989, 173:215-217.
    • (1989) European Journal of Pharmacology , vol.173 , pp. 215-217
    • Boja, J.W.1    Kuhar, M.J.2
  • 8
    • 34247545124 scopus 로고    scopus 로고
    • D-2 receptors regulate dopamine transporter function via an extracellular signal-regulated kinases 1 and 2-dependent and phosphoinositide 3 kinase-independent mechanism
    • Bolan E.A., Kivell B., Jaligam V., Oz M., Jayanthi L.D., Han Y., et al. D-2 receptors regulate dopamine transporter function via an extracellular signal-regulated kinases 1 and 2-dependent and phosphoinositide 3 kinase-independent mechanism. Molecular Pharmacology 2007, 71(5):1222-1232.
    • (2007) Molecular Pharmacology , vol.71 , Issue.5 , pp. 1222-1232
    • Bolan, E.A.1    Kivell, B.2    Jaligam, V.3    Oz, M.4    Jayanthi, L.D.5    Han, Y.6
  • 9
    • 70350166693 scopus 로고    scopus 로고
    • Potential anxiolytic- and antidepressant-like effects of salvinorin A, the main active ingredient of Salvia Divinorum, in rodents
    • Braida D., Capurro V., Zani A., Rubino T., Vigano D., Parolaro D., et al. Potential anxiolytic- and antidepressant-like effects of salvinorin A, the main active ingredient of Salvia Divinorum, in rodents. British Journal of Pharmacology 2009, 157(5):844-853.
    • (2009) British Journal of Pharmacology , vol.157 , Issue.5 , pp. 844-853
    • Braida, D.1    Capurro, V.2    Zani, A.3    Rubino, T.4    Vigano, D.5    Parolaro, D.6
  • 10
    • 38049032934 scopus 로고    scopus 로고
    • Involvement of kappa-opioid and endocannabinoid system on salvinorin A-induced reward
    • Braida D., Limonta V., Capurro V., Fadda P., Rubino T., Mascia P., et al. Involvement of kappa-opioid and endocannabinoid system on salvinorin A-induced reward. Biological Psychiatry 2008, 63(3):286-292.
    • (2008) Biological Psychiatry , vol.63 , Issue.3 , pp. 286-292
    • Braida, D.1    Limonta, V.2    Capurro, V.3    Fadda, P.4    Rubino, T.5    Mascia, P.6
  • 11
    • 33846799142 scopus 로고    scopus 로고
    • Hallucinatory and rewarding effect of salvinorin A in zebrafish: Kappa-opioid and CB1-cannabinoid receptor involvement
    • Braida D., Limonta V., Pegorini S., Zani A., Guerini-Rocco C., Gori E., et al. Hallucinatory and rewarding effect of salvinorin A in zebrafish: Kappa-opioid and CB1-cannabinoid receptor involvement. Psychopharmacology 2007, 190(4):441-448.
    • (2007) Psychopharmacology , vol.190 , Issue.4 , pp. 441-448
    • Braida, D.1    Limonta, V.2    Pegorini, S.3    Zani, A.4    Guerini-Rocco, C.5    Gori, E.6
  • 12
    • 35548997505 scopus 로고    scopus 로고
    • Stress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria
    • Bruchas M.R., Land B.B., Aita M., Xu M., Barot S.K., Li S., et al. Stress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria. Journal of Neuroscience 2007, 27(43):11614-11623.
    • (2007) Journal of Neuroscience , vol.27 , Issue.43 , pp. 11614-11623
    • Bruchas, M.R.1    Land, B.B.2    Aita, M.3    Xu, M.4    Barot, S.K.5    Li, S.6
  • 13
    • 75149183092 scopus 로고    scopus 로고
    • The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors
    • Bruchas M., Land B., Chavkin C. The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors. Brain Research 2010, 1314:44-55.
    • (2010) Brain Research , vol.1314 , pp. 44-55
    • Bruchas, M.1    Land, B.2    Chavkin, C.3
  • 14
    • 77954039086 scopus 로고    scopus 로고
    • CRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behavior
    • Bruchas M.R., Land B.B., Lemos J.C., Chavkin C. CRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behavior. PLoS ONE 2009, 4(12):e8528.
    • (2009) PLoS ONE , vol.4 , Issue.12
    • Bruchas, M.R.1    Land, B.B.2    Lemos, J.C.3    Chavkin, C.4
  • 15
    • 79961197759 scopus 로고    scopus 로고
    • Selective p38 alpha MAPK deletion in serotonergic neurons produces stress resilience in models of depression and addiction
    • Bruchas M.R., Schindler A.G., Shankar H., Messinger D.I., Miyatake M., Land B.B., et al. Selective p38 alpha MAPK deletion in serotonergic neurons produces stress resilience in models of depression and addiction. Neuron 2011, 71(3):498-511.
    • (2011) Neuron , vol.71 , Issue.3 , pp. 498-511
    • Bruchas, M.R.1    Schindler, A.G.2    Shankar, H.3    Messinger, D.I.4    Miyatake, M.5    Land, B.B.6
  • 16
    • 1642340346 scopus 로고    scopus 로고
    • The plant-derived hallucinogen, salvinorin A, produces kappa-opioid agonist-like discriminative effects in rhesus monkeys
    • Butelman E.R., Harris T.J., Kreek M.J. The plant-derived hallucinogen, salvinorin A, produces kappa-opioid agonist-like discriminative effects in rhesus monkeys. Psychopharmacology 2004, 172(2):220-224.
    • (2004) Psychopharmacology , vol.172 , Issue.2 , pp. 220-224
    • Butelman, E.R.1    Harris, T.J.2    Kreek, M.J.3
  • 17
    • 33845912189 scopus 로고    scopus 로고
    • Effects of salvinorin A, a kappa-opioid hallucinogen, on a neuroendocrine biomarker assay in nonhuman primates with high kappa-receptor homology to humans
    • Butelman E.R., Mandau M., Tidgewell K., Prisinzano T.E., Yuferov V., Kreek M.J. Effects of salvinorin A, a kappa-opioid hallucinogen, on a neuroendocrine biomarker assay in nonhuman primates with high kappa-receptor homology to humans. Journal of Pharmacology and Experimental Therapeutics 2007, 320(1):300-306.
    • (2007) Journal of Pharmacology and Experimental Therapeutics , vol.320 , Issue.1 , pp. 300-306
    • Butelman, E.R.1    Mandau, M.2    Tidgewell, K.3    Prisinzano, T.E.4    Yuferov, V.5    Kreek, M.J.6
  • 18
    • 59649116688 scopus 로고    scopus 로고
    • Unconditioned behavioral effects of the powerful kappa-opioid hallucinogen salvinorin A in nonhuman primates: Fast onset and entry into cerebrospinal fluid
    • Butelman E.R., Prisinzano T.E., Deng H., Rus S., Kreek M.J. Unconditioned behavioral effects of the powerful kappa-opioid hallucinogen salvinorin A in nonhuman primates: Fast onset and entry into cerebrospinal fluid. Journal of Pharmacology and Experimental Therapeutics 2009, 328(2):588-597.
    • (2009) Journal of Pharmacology and Experimental Therapeutics , vol.328 , Issue.2 , pp. 588-597
    • Butelman, E.R.1    Prisinzano, T.E.2    Deng, H.3    Rus, S.4    Kreek, M.J.5
  • 19
    • 77953286927 scopus 로고    scopus 로고
    • The discriminative effects of the kappa-opioid hallucinogen salvinorin A in nonhuman primates: Dissociation from classic hallucinogen effects
    • Butelman E.R., Rus S., Prisinzano T.E., Kreek M.J. The discriminative effects of the kappa-opioid hallucinogen salvinorin A in nonhuman primates: Dissociation from classic hallucinogen effects. Psychopharmacology 2010, 210(2):253-262.
    • (2010) Psychopharmacology , vol.210 , Issue.2 , pp. 253-262
    • Butelman, E.R.1    Rus, S.2    Prisinzano, T.E.3    Kreek, M.J.4
  • 20
    • 84866770393 scopus 로고    scopus 로고
    • Kappa-opioid receptor/dynorphin system: Genetic and pharmacotherapeutic implications for addiction
    • Butelman E.R., Yuferov V., Kreek M.J. Kappa-opioid receptor/dynorphin system: Genetic and pharmacotherapeutic implications for addiction. Trends in Neurosciences 2012, 35(10):587-596.
    • (2012) Trends in Neurosciences , vol.35 , Issue.10 , pp. 587-596
    • Butelman, E.R.1    Yuferov, V.2    Kreek, M.J.3
  • 23
    • 84875734011 scopus 로고    scopus 로고
    • Development of kappa-opioid receptor antagonists
    • Carroll F.I., Carlezon W.A. Development of kappa-opioid receptor antagonists. Journal of Medicinal Chemistry 2013, 56(6):2178-2195. http://www.ncbi.nlm.nih.gov/pubmed/23360448.
    • (2013) Journal of Medicinal Chemistry , vol.56 , Issue.6 , pp. 2178-2195
    • Carroll, F.I.1    Carlezon, W.A.2
  • 24
    • 51749123754 scopus 로고    scopus 로고
    • Exposure to the selective kappa-opioid receptor agonist salvinorin A modulates the behavioral and molecular effects of cocaine in rats
    • Chartoff E.H., Potter D., Damez-Werno D., Cohen B.M., Carlezon W.A. Exposure to the selective kappa-opioid receptor agonist salvinorin A modulates the behavioral and molecular effects of cocaine in rats. Neuropsychopharmacology 2008, 33(11):2676-2687.
    • (2008) Neuropsychopharmacology , vol.33 , Issue.11 , pp. 2676-2687
    • Chartoff, E.H.1    Potter, D.2    Damez-Werno, D.3    Cohen, B.M.4    Carlezon, W.A.5
  • 25
    • 80054099649 scopus 로고    scopus 로고
    • Blockade of kappa opioid receptors attenuates the development of depressive-like behaviors induced by cocaine withdrawal in rats
    • Chartoff E., Sawyer A., Rachlin A., Potter D., Pliakas A., Carlezon W.A. Blockade of kappa opioid receptors attenuates the development of depressive-like behaviors induced by cocaine withdrawal in rats. Neuropharmacology 2012, 62(1):167-176.
    • (2012) Neuropharmacology , vol.62 , Issue.1 , pp. 167-176
    • Chartoff, E.1    Sawyer, A.2    Rachlin, A.3    Potter, D.4    Pliakas, A.5    Carlezon, W.A.6
  • 26
    • 78649666302 scopus 로고    scopus 로고
    • The therapeutic potential of kappa-opioids for treatment of pain and addiction
    • Chavkin C. The therapeutic potential of kappa-opioids for treatment of pain and addiction. Neuropsychopharmacology 2011, 36(1):369-370.
    • (2011) Neuropsychopharmacology , vol.36 , Issue.1 , pp. 369-370
    • Chavkin, C.1
  • 27
    • 0020029345 scopus 로고
    • Dynorphin is a specific endogenous ligand of the kappa-opioid receptor
    • Chavkin C., James I.F., Goldstein A. Dynorphin is a specific endogenous ligand of the kappa-opioid receptor. Science 1982, 215(4531):413-415.
    • (1982) Science , vol.215 , Issue.4531 , pp. 413-415
    • Chavkin, C.1    James, I.F.2    Goldstein, A.3
  • 28
    • 1342265861 scopus 로고    scopus 로고
    • Salvinorin A, an active component of the hallucinogenic sage Salvia divinorum is a highly efficacious kappa-opioid receptor agonist: Structural and functional considerations
    • Chavkin C., Sud S., Jin W.Z., Stewart J., Zjawiony J.K., Siebert D.J., et al. Salvinorin A, an active component of the hallucinogenic sage Salvia divinorum is a highly efficacious kappa-opioid receptor agonist: Structural and functional considerations. Journal of Pharmacology and Experimental Therapeutics 2004, 308(3):1197-1203.
    • (2004) Journal of Pharmacology and Experimental Therapeutics , vol.308 , Issue.3 , pp. 1197-1203
    • Chavkin, C.1    Sud, S.2    Jin, W.Z.3    Stewart, J.4    Zjawiony, J.K.5    Siebert, D.J.6
  • 29
    • 19044391142 scopus 로고    scopus 로고
    • Endogenous kappa-opioid receptor systems regulate mesoaccumbal dopamine dynamics and vulnerability to cocaine
    • Chefer V.I., Czyzyk T., Bolan E.A., Moron J., Pintar J.E., Shippenberg T.S. Endogenous kappa-opioid receptor systems regulate mesoaccumbal dopamine dynamics and vulnerability to cocaine. Journal of Neuroscience 2005, 25(20):5029-5037.
    • (2005) Journal of Neuroscience , vol.25 , Issue.20 , pp. 5029-5037
    • Chefer, V.I.1    Czyzyk, T.2    Bolan, E.A.3    Moron, J.4    Pintar, J.E.5    Shippenberg, T.S.6
  • 30
    • 0034669069 scopus 로고    scopus 로고
    • Kappa-opioid receptor activation prevents alterations in mesocortical dopamine neurotransmission that occur during abstinence from cocaine
    • Chefer V.I., Moron J.A., Hope B., Rea W., Shippenberg T.S. Kappa-opioid receptor activation prevents alterations in mesocortical dopamine neurotransmission that occur during abstinence from cocaine. Neuroscience 2000, 101(3):619-627.
    • (2000) Neuroscience , vol.101 , Issue.3 , pp. 619-627
    • Chefer, V.I.1    Moron, J.A.2    Hope, B.3    Rea, W.4    Shippenberg, T.S.5
  • 31
    • 0142148146 scopus 로고    scopus 로고
    • Substrate-induced trafficking of the dopamine transporter in heterologously expressing cells and in rat striatal synaptosomal preparations
    • Chi L., Reith M.E. Substrate-induced trafficking of the dopamine transporter in heterologously expressing cells and in rat striatal synaptosomal preparations. The Journal of Pharmacology and Experimental Therapeutics 2003, 307(2):729-736.
    • (2003) The Journal of Pharmacology and Experimental Therapeutics , vol.307 , Issue.2 , pp. 729-736
    • Chi, L.1    Reith, M.E.2
  • 32
    • 0035943424 scopus 로고    scopus 로고
    • Effects of kappa-opioid receptor agonists on long-term cocaine use and dopamine neurotransmission
    • Collins S.L., D'Addario C., Izenwasser S. Effects of kappa-opioid receptor agonists on long-term cocaine use and dopamine neurotransmission. European Journal of Pharmacology 2001, 426(1-2):25-34.
    • (2001) European Journal of Pharmacology , vol.426 , Issue.1-2 , pp. 25-34
    • Collins, S.L.1    D'Addario, C.2    Izenwasser, S.3
  • 33
    • 0036722634 scopus 로고    scopus 로고
    • Chronic cocaine increases kappa-opioid receptor density: Lack of effect by selective dopamine uptake inhibitors
    • Collins S.L., Kunko P.M., Ladenheim B., Cadet J.L., Carroll F.I., Izenwasser S. Chronic cocaine increases kappa-opioid receptor density: Lack of effect by selective dopamine uptake inhibitors. Synapse 2002, 45(3):153-158.
    • (2002) Synapse , vol.45 , Issue.3 , pp. 153-158
    • Collins, S.L.1    Kunko, P.M.2    Ladenheim, B.3    Cadet, J.L.4    Carroll, F.I.5    Izenwasser, S.6
  • 34
    • 0027294728 scopus 로고
    • Cocaine self-administration increases preprodynorphin, but not c-fos, messenger-RNA in rat striatum
    • Daunais J.B., Roberts D.C.S., McGinty J.F. Cocaine self-administration increases preprodynorphin, but not c-fos, messenger-RNA in rat striatum. Neuroreport 1993, 4(5):543-546.
    • (1993) Neuroreport , vol.4 , Issue.5 , pp. 543-546
    • Daunais, J.B.1    Roberts, D.C.S.2    McGinty, J.F.3
  • 35
    • 0023836656 scopus 로고
    • Opposite effects of mu-opiate and kappa-opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats
    • Dichiara G., Imperato A. Opposite effects of mu-opiate and kappa-opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats. Journal of Pharmacology and Experimental Therapeutics 1988, 244(3):1067-1080.
    • (1988) Journal of Pharmacology and Experimental Therapeutics , vol.244 , Issue.3 , pp. 1067-1080
    • Dichiara, G.1    Imperato, A.2
  • 37
    • 77953284983 scopus 로고    scopus 로고
    • Depressive-like effects of the kappa opioid receptor agonist salvinorin A are associated with decreased phasic dopamine release in the nucleus accumbens
    • Ebner S.R., Roitman M.F., Potter D.N., Rachlin A.B., Chartoff E.H. Depressive-like effects of the kappa opioid receptor agonist salvinorin A are associated with decreased phasic dopamine release in the nucleus accumbens. Psychopharmacology 2010, 210(2):241-252.
    • (2010) Psychopharmacology , vol.210 , Issue.2 , pp. 241-252
    • Ebner, S.R.1    Roitman, M.F.2    Potter, D.N.3    Rachlin, A.B.4    Chartoff, E.H.5
  • 38
    • 0034027391 scopus 로고    scopus 로고
    • Modulation of the neurotoxic effects of methamphetamine by the selective kappa-opioid receptor agonist U69593
    • El Daly E., Chefer V., Sandill S., Shippenberg T.S. Modulation of the neurotoxic effects of methamphetamine by the selective kappa-opioid receptor agonist U69593. Journal of Neurochemistry 2000, 74(4):1553-1562.
    • (2000) Journal of Neurochemistry , vol.74 , Issue.4 , pp. 1553-1562
    • El Daly, E.1    Chefer, V.2    Sandill, S.3    Shippenberg, T.S.4
  • 39
  • 41
    • 63849284330 scopus 로고    scopus 로고
    • Dopamine and amphetamine rapidly increase dopamine transporter trafficking to the surface: Live-cell imaging using total internal reflection fluorescence microscopy
    • Furman C.A., Chen R., Guptaroy B., Zhang M., Holz R.W., Gnegy M. Dopamine and amphetamine rapidly increase dopamine transporter trafficking to the surface: Live-cell imaging using total internal reflection fluorescence microscopy. Journal of Neuroscience 2009, 29(10):3328-3336.
    • (2009) Journal of Neuroscience , vol.29 , Issue.10 , pp. 3328-3336
    • Furman, C.A.1    Chen, R.2    Guptaroy, B.3    Zhang, M.4    Holz, R.W.5    Gnegy, M.6
  • 42
    • 43149092465 scopus 로고    scopus 로고
    • Effects of acute and repeated administration of salvinorin A on dopamine function in the rat dorsal striatum
    • Gehrke B.J., Chefer V.I., Shippenberg T.S. Effects of acute and repeated administration of salvinorin A on dopamine function in the rat dorsal striatum. Psychopharmacology 2008, 197(3):509-517.
    • (2008) Psychopharmacology , vol.197 , Issue.3 , pp. 509-517
    • Gehrke, B.J.1    Chefer, V.I.2    Shippenberg, T.S.3
  • 43
    • 0029001901 scopus 로고
    • Kappa opioid inhibition of morphine and cocaine self-administration in rats
    • Glick S.D., Maisonneuve I.M., Raucci J., Archer S. Kappa opioid inhibition of morphine and cocaine self-administration in rats. Brain Research 1995, 681:147-152.
    • (1995) Brain Research , vol.681 , pp. 147-152
    • Glick, S.D.1    Maisonneuve, I.M.2    Raucci, J.3    Archer, S.4
  • 44
    • 0020062482 scopus 로고
    • Immunoreactive dynorphin in human-brain and pituitary
    • Gramsch C., Hollt V., Pasi A., Mehraein P., Herz A. Immunoreactive dynorphin in human-brain and pituitary. Brain Research 1982, 233(1):65-74.
    • (1982) Brain Research , vol.233 , Issue.1 , pp. 65-74
    • Gramsch, C.1    Hollt, V.2    Pasi, A.3    Mehraein, P.4    Herz, A.5
  • 45
    • 69649088499 scopus 로고    scopus 로고
    • Salvinorin A exerts opposite presynaptic controls on neurotransmitter exocytosis from mouse brain nerve terminals
    • Grilli M., Neri E., Zappettini S., Massa F., Bisio A., Romussi G., et al. Salvinorin A exerts opposite presynaptic controls on neurotransmitter exocytosis from mouse brain nerve terminals. Neuropharmacology 2009, 57(5-6):523-530.
    • (2009) Neuropharmacology , vol.57 , Issue.5-6 , pp. 523-530
    • Grilli, M.1    Neri, E.2    Zappettini, S.3    Massa, F.4    Bisio, A.5    Romussi, G.6
  • 46
    • 33846456218 scopus 로고    scopus 로고
    • An opioid agonist that does not induce mu-opioid receptor-Arrestin interactions or receptor internalization
    • Groer C.E., Tidgewell K., Moyer R.A., Harding W.W., Rothman R.B., Prisinzano T.E., et al. An opioid agonist that does not induce mu-opioid receptor-Arrestin interactions or receptor internalization. Molecular Pharmacology 2007, 71(2):549-557.
    • (2007) Molecular Pharmacology , vol.71 , Issue.2 , pp. 549-557
    • Groer, C.E.1    Tidgewell, K.2    Moyer, R.A.3    Harding, W.W.4    Rothman, R.B.5    Prisinzano, T.E.6
  • 47
    • 34548652748 scopus 로고    scopus 로고
    • Salvia divinorum and salvinorin A: An update on pharmacology and analytical methodology
    • Grundmann O., Phipps S.M., Zadezensky I., Butterweck V. Salvia divinorum and salvinorin A: An update on pharmacology and analytical methodology. Planta Medica 2007, 73(10):1039-1046.
    • (2007) Planta Medica , vol.73 , Issue.10 , pp. 1039-1046
    • Grundmann, O.1    Phipps, S.M.2    Zadezensky, I.3    Butterweck, V.4
  • 48
    • 0036796804 scopus 로고    scopus 로고
    • Brief, repeated exposure to substrates down-regulates dopamine transporter function in Xenopus oocytes in vitro and rat dorsal striatum in vivo
    • Gulley J.M., Doolen S., Zahniser N.R. Brief, repeated exposure to substrates down-regulates dopamine transporter function in Xenopus oocytes in vitro and rat dorsal striatum in vivo. Journal of Neurochemistry 2002, 83(2):400-411.
    • (2002) Journal of Neurochemistry , vol.83 , Issue.2 , pp. 400-411
    • Gulley, J.M.1    Doolen, S.2    Zahniser, N.R.3
  • 49
    • 33846811403 scopus 로고    scopus 로고
    • Association of functional catechol O-methyl transferase (COMT) Val108Met polymorphism with smoking severity and age of smoking initiation in Chinese male smokers
    • Guo S., Zhou D.F., Sun H.Q., Wu G.Y., Haile C.N., Kosten T.A., et al. Association of functional catechol O-methyl transferase (COMT) Val108Met polymorphism with smoking severity and age of smoking initiation in Chinese male smokers. Psychopharmacology 2007, 190(4):449-456.
    • (2007) Psychopharmacology , vol.190 , Issue.4 , pp. 449-456
    • Guo, S.1    Zhou, D.F.2    Sun, H.Q.3    Wu, G.Y.4    Haile, C.N.5    Kosten, T.A.6
  • 50
    • 0035205217 scopus 로고    scopus 로고
    • Antidepressant effects of the herb salvia divinorum: A case report
    • Hanes K.R. Antidepressant effects of the herb salvia divinorum: A case report. Journal of Clinical Psychopharmacology 2001, 21(6):634-635.
    • (2001) Journal of Clinical Psychopharmacology , vol.21 , Issue.6 , pp. 634-635
    • Hanes, K.R.1
  • 51
    • 84866326647 scopus 로고    scopus 로고
    • Antidepressive effects of the kappa-opioid receptor agonist salvinorin A in a rat model of anhedonia
    • Harden M.T., Smith S.E., Niehoff J.A., McCurdy C.R., Taylor G.T. Antidepressive effects of the kappa-opioid receptor agonist salvinorin A in a rat model of anhedonia. Behavioural Pharmacology 2012, 23(7):710-715.
    • (2012) Behavioural Pharmacology , vol.23 , Issue.7 , pp. 710-715
    • Harden, M.T.1    Smith, S.E.2    Niehoff, J.A.3    McCurdy, C.R.4    Taylor, G.T.5
  • 53
    • 0031691534 scopus 로고    scopus 로고
    • Increased responsiveness of mesolimbic and mesostriatal dopamine neurons to cocaine following repeated administration of a selective kappa-opioid receptor agonist
    • Heidbreder C.A., Schenk S., Partridge B., Shippenberg T.S. Increased responsiveness of mesolimbic and mesostriatal dopamine neurons to cocaine following repeated administration of a selective kappa-opioid receptor agonist. Synapse 1998, 30(3):255-262.
    • (1998) Synapse , vol.30 , Issue.3 , pp. 255-262
    • Heidbreder, C.A.1    Schenk, S.2    Partridge, B.3    Shippenberg, T.S.4
  • 54
    • 0033573241 scopus 로고    scopus 로고
    • Opioid peptide receptor studies. 10. Nor-BNI differentially inhibits kappa receptor agonist-induced G-protein activation in the guinea pig caudate: Further evidence of kappa receptor heterogeneity
    • Heyliger S.O., Jackson C., Rice K.C., Rothman R.B. Opioid peptide receptor studies. 10. Nor-BNI differentially inhibits kappa receptor agonist-induced G-protein activation in the guinea pig caudate: Further evidence of kappa receptor heterogeneity. Synapse 1999, 34(4):256-265.
    • (1999) Synapse , vol.34 , Issue.4 , pp. 256-265
    • Heyliger, S.O.1    Jackson, C.2    Rice, K.C.3    Rothman, R.B.4
  • 55
    • 67349123137 scopus 로고    scopus 로고
    • Metabolic changes in the rodent brain after acute administration of salvinorin A
    • Hooker J.M., Patel V., Kothari S., Schiffer W.K. Metabolic changes in the rodent brain after acute administration of salvinorin A. Molecular Imaging and Biology 2009, 11(3):137-143.
    • (2009) Molecular Imaging and Biology , vol.11 , Issue.3 , pp. 137-143
    • Hooker, J.M.1    Patel, V.2    Kothari, S.3    Schiffer, W.K.4
  • 56
    • 44449102022 scopus 로고    scopus 로고
    • Pharmacokinetics of the potent hallucinogen, salvinorin A in primates parallels the rapid onset and short duration of effects in humans
    • Hooker J.M., Xu Y., Schiffer W., Shea C., Carter P., Fowler J.S. Pharmacokinetics of the potent hallucinogen, salvinorin A in primates parallels the rapid onset and short duration of effects in humans. NeuroImage 2008, 41(3):1044-1050.
    • (2008) NeuroImage , vol.41 , Issue.3 , pp. 1044-1050
    • Hooker, J.M.1    Xu, Y.2    Schiffer, W.3    Shea, C.4    Carter, P.5    Fowler, J.S.6
  • 57
    • 0027493973 scopus 로고
    • Differential antagonism of bremazocine-induced and U69,593-induced antinociception by quadazocine-Further functional evidence of opioid kappa-receptor multiplicity in the mouse
    • Horan P.J., Decosta B.R., Rice K., Haaseth R.C., Hruby V.J., Porreca F. Differential antagonism of bremazocine-induced and U69,593-induced antinociception by quadazocine-Further functional evidence of opioid kappa-receptor multiplicity in the mouse. Journal of Pharmacology and Experimental Therapeutics 1993, 266(2):926-933.
    • (1993) Journal of Pharmacology and Experimental Therapeutics , vol.266 , Issue.2 , pp. 926-933
    • Horan, P.J.1    Decosta, B.R.2    Rice, K.3    Haaseth, R.C.4    Hruby, V.J.5    Porreca, F.6
  • 58
    • 0027462309 scopus 로고
    • Molecular alterations in the neostriatum of human cocaine addicts
    • Hurd Y.L., Herkenham M. Molecular alterations in the neostriatum of human cocaine addicts. Synapse 1993, 13(4):357-369.
    • (1993) Synapse , vol.13 , Issue.4 , pp. 357-369
    • Hurd, Y.L.1    Herkenham, M.2
  • 59
    • 0027185579 scopus 로고
    • No evidence for presynaptic opioid receptors on cholinergic, but presence of kappa-receptors on dopaminergic-neurons in the rabbit caudate-nucleus-Involvement of endogenous opioids
    • Jackisch R., Hotz H., Hertting G. No evidence for presynaptic opioid receptors on cholinergic, but presence of kappa-receptors on dopaminergic-neurons in the rabbit caudate-nucleus-Involvement of endogenous opioids. Naunyn-Schmiedebergs Archives of Pharmacology 1993, 348(3):234-241.
    • (1993) Naunyn-Schmiedebergs Archives of Pharmacology , vol.348 , Issue.3 , pp. 234-241
    • Jackisch, R.1    Hotz, H.2    Hertting, G.3
  • 60
    • 79955531128 scopus 로고    scopus 로고
    • Human psychopharmacology and dose-effects of salvinorin A, a kappa opioid agonist hallucinogen present in the plant Salvia divinorum
    • Johnson M.W., MacLean K.A., Reissig C.J., Prisinzano T.E., Griffiths R.R. Human psychopharmacology and dose-effects of salvinorin A, a kappa opioid agonist hallucinogen present in the plant Salvia divinorum. Drug and Alcohol Dependence 2011, 115(1-2):150-155.
    • (2011) Drug and Alcohol Dependence , vol.115 , Issue.1-2 , pp. 150-155
    • Johnson, M.W.1    MacLean, K.A.2    Reissig, C.J.3    Prisinzano, T.E.4    Griffiths, R.R.5
  • 61
    • 77954758120 scopus 로고    scopus 로고
    • Salvinorin A fails to substitute for the discriminative stimulus effects of LSD or ketamine in Sprague-Dawley rats
    • Killinger B.A., Peet M.M., Baker L.E. Salvinorin A fails to substitute for the discriminative stimulus effects of LSD or ketamine in Sprague-Dawley rats. Pharmacology, Biochemistry, and Behavior 2010, 96(3):260-265.
    • (2010) Pharmacology, Biochemistry, and Behavior , vol.96 , Issue.3 , pp. 260-265
    • Killinger, B.A.1    Peet, M.M.2    Baker, L.E.3
  • 62
    • 77953287151 scopus 로고    scopus 로고
    • Kappa opioids and the modulation of pain
    • Kivell B., Prisinzano T.E. Kappa opioids and the modulation of pain. Psychopharmacology 2010, 210(2):109-119.
    • (2010) Psychopharmacology , vol.210 , Issue.2 , pp. 109-119
    • Kivell, B.1    Prisinzano, T.E.2
  • 63
    • 75149118146 scopus 로고    scopus 로고
    • Dynorphin, stress, and depression
    • Knoll A.T., Carlezon W.A. Dynorphin, stress, and depression. Brain Research 2010, 1314:56-73.
    • (2010) Brain Research , vol.1314 , pp. 56-73
    • Knoll, A.T.1    Carlezon, W.A.2
  • 64
    • 46149120544 scopus 로고    scopus 로고
    • A role for brain stress systems in addiction
    • Koob G.F. A role for brain stress systems in addiction. Neuron 2008, 59(1):11-34.
    • (2008) Neuron , vol.59 , Issue.1 , pp. 11-34
    • Koob, G.F.1
  • 66
    • 0029855573 scopus 로고    scopus 로고
    • Cocaine, dopamine and the endogenous opioid system
    • Kreek M.J. Cocaine, dopamine and the endogenous opioid system. Journal of Addictive Diseases 1996, 15(4):73-96.
    • (1996) Journal of Addictive Diseases , vol.15 , Issue.4 , pp. 73-96
    • Kreek, M.J.1
  • 68
    • 2442678807 scopus 로고    scopus 로고
    • Agonist-induced regulation and trafficking of kappa opioid receptors
    • Liu-Chen L.Y. Agonist-induced regulation and trafficking of kappa opioid receptors. Life Sciences 2004, 75(5):511-536.
    • (2004) Life Sciences , vol.75 , Issue.5 , pp. 511-536
    • Liu-Chen, L.Y.1
  • 71
    • 84877148871 scopus 로고    scopus 로고
    • Dose-related effects of salvinorin A in humans: Dissociative, hallucinogenic, and memory effects
    • MacLean K.A., Johnson M.W., Reissig C.J., Prisinzano T.E., Griffiths R.R. Dose-related effects of salvinorin A in humans: Dissociative, hallucinogenic, and memory effects. Psychopharmacology 2013, 226(2):381-392.
    • (2013) Psychopharmacology , vol.226 , Issue.2 , pp. 381-392
    • MacLean, K.A.1    Johnson, M.W.2    Reissig, C.J.3    Prisinzano, T.E.4    Griffiths, R.R.5
  • 72
    • 0242610916 scopus 로고    scopus 로고
    • Kappa-opioid agonists directly inhibit midbrain dopaminergic neurons
    • Margolis E.B., Hjelmstad G.O., Bonci A., Fields H.L. Kappa-opioid agonists directly inhibit midbrain dopaminergic neurons. Journal of Neuroscience 2003, 23(31):9981-9986.
    • (2003) Journal of Neuroscience , vol.23 , Issue.31 , pp. 9981-9986
    • Margolis, E.B.1    Hjelmstad, G.O.2    Bonci, A.3    Fields, H.L.4
  • 73
    • 22544461345 scopus 로고    scopus 로고
    • Translocation of dynorphin neuropeptides across the plasma membrane-A putative mechanism of signal transmission
    • Marinova Z., Vukojevic V., Surcheva S., Yakovleva T., Cebers G., Pasikova N., et al. Translocation of dynorphin neuropeptides across the plasma membrane-A putative mechanism of signal transmission. Journal of Biological Chemistry 2005, 280(28):26360-26370.
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.28 , pp. 26360-26370
    • Marinova, Z.1    Vukojevic, V.2    Surcheva, S.3    Yakovleva, T.4    Cebers, G.5    Pasikova, N.6
  • 75
    • 56749092253 scopus 로고    scopus 로고
    • Kappa opioids promote the proliferation of astrocytes via G beta gamma and beta-arrestin 2-dependent MAPK-mediated pathways
    • McLennan G.P., Kiss A., Miyatake M., Belcheva M.M., Chambers K.T., Pozek J.J., et al. Kappa opioids promote the proliferation of astrocytes via G beta gamma and beta-arrestin 2-dependent MAPK-mediated pathways. Journal of Neurochemistry 2008, 107(6):1753-1765.
    • (2008) Journal of Neurochemistry , vol.107 , Issue.6 , pp. 1753-1765
    • McLennan, G.P.1    Kiss, A.2    Miyatake, M.3    Belcheva, M.M.4    Chambers, K.T.5    Pozek, J.J.6
  • 76
    • 0032437428 scopus 로고    scopus 로고
    • Effects of kappa opioid agonists on cocaine- and food-maintained responding by rhesus monkeys
    • Mello N.K., Negus S.S. Effects of kappa opioid agonists on cocaine- and food-maintained responding by rhesus monkeys. Journal of Pharmacology and Experimental Therapeutics 1998, 286(2):812-824.
    • (1998) Journal of Pharmacology and Experimental Therapeutics , vol.286 , Issue.2 , pp. 812-824
    • Mello, N.K.1    Negus, S.S.2
  • 78
    • 33644962688 scopus 로고    scopus 로고
    • Big dynorphin as a putative endogenous ligand for the kappa-opioid receptor
    • Merg F., Filliol D., Usynin I., Bazov I., Bark N., Hurd Y.L., et al. Big dynorphin as a putative endogenous ligand for the kappa-opioid receptor. Journal of Neurochemistry 2006, 97(1):292-301.
    • (2006) Journal of Neurochemistry , vol.97 , Issue.1 , pp. 292-301
    • Merg, F.1    Filliol, D.2    Usynin, I.3    Bazov, I.4    Bark, N.5    Hurd, Y.L.6
  • 79
    • 26844458361 scopus 로고    scopus 로고
    • A single injection of the kappa opioid antagonist norbinaltorphimine increases ethanol consumption in rats
    • Mitchell J.M., Liang M.T., Fields H.I. A single injection of the kappa opioid antagonist norbinaltorphimine increases ethanol consumption in rats. Psychopharmacology 2005, 182:384-392.
    • (2005) Psychopharmacology , vol.182 , pp. 384-392
    • Mitchell, J.M.1    Liang, M.T.2    Fields, H.I.3
  • 80
    • 72149090907 scopus 로고    scopus 로고
    • Effect of kappa-opioid receptor agonists U69593, U50488H, spiradoline and salvinorin A on cocaine-induced drug-seeking in rats
    • Morani A.S., Kivell B., Prisinzano T.E., Schenk S. Effect of kappa-opioid receptor agonists U69593, U50488H, spiradoline and salvinorin A on cocaine-induced drug-seeking in rats. Pharmacology, Biochemistry, and Behavior 2009, 94(2):244-249.
    • (2009) Pharmacology, Biochemistry, and Behavior , vol.94 , Issue.2 , pp. 244-249
    • Morani, A.S.1    Kivell, B.2    Prisinzano, T.E.3    Schenk, S.4
  • 81
    • 84858702496 scopus 로고    scopus 로고
    • A single injection of a novel kappa opioid receptor agonist salvinorin A attenuates the expression of cocaine-induced behavioral sensitization in rats
    • Morani A.S., Schenk S., Prisinzano T.E., Kivell B.M. A single injection of a novel kappa opioid receptor agonist salvinorin A attenuates the expression of cocaine-induced behavioral sensitization in rats. Behavioural Pharmacology 2012, 23(2):162-170.
    • (2012) Behavioural Pharmacology , vol.23 , Issue.2 , pp. 162-170
    • Morani, A.S.1    Schenk, S.2    Prisinzano, T.E.3    Kivell, B.M.4
  • 82
    • 84890117454 scopus 로고    scopus 로고
    • The 2-methoxy methyl analogue of salvinorin A attenuates cocaine-induced drug seeking and sucrose reinforcements in rats
    • Morani A.S., Ewald A., Prevatt-Smith K.M., Prisinzano T.E., Kivell B.M. The 2-methoxy methyl analogue of salvinorin A attenuates cocaine-induced drug seeking and sucrose reinforcements in rats. European Journal of Pharmacology 2013, 720(1-3):69-76.
    • (2013) European Journal of Pharmacology , vol.720 , Issue.1-3 , pp. 69-76
    • Morani, A.S.1    Ewald, A.2    Prevatt-Smith, K.M.3    Prisinzano, T.E.4    Kivell, B.M.5
  • 83
    • 84880601990 scopus 로고    scopus 로고
    • Involvement of dopamine D2 receptor signal transduction in the discriminative stimulus effects of the kappa-opioid receptor agonist U-50,488H in rats
    • Mori T., Yoshizawa K., Ueno T., Nishiwaki M., Shimizu N., Shibasaki M., et al. Involvement of dopamine D2 receptor signal transduction in the discriminative stimulus effects of the kappa-opioid receptor agonist U-50,488H in rats. Behavioural Pharmacology 2013, 24(4):275-281.
    • (2013) Behavioural Pharmacology , vol.24 , Issue.4 , pp. 275-281
    • Mori, T.1    Yoshizawa, K.2    Ueno, T.3    Nishiwaki, M.4    Shimizu, N.5    Shibasaki, M.6
  • 84
    • 0141569571 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase regulates dopamine transporter surface expression and dopamine transport capacity
    • Moron J.A., Zakharova I., Ferrer J.V., Merrill G.A., Hope B., Lafer E.M., et al. Mitogen-activated protein kinase regulates dopamine transporter surface expression and dopamine transport capacity. Journal of Neuroscience 2003, 23(24):8480-8488.
    • (2003) Journal of Neuroscience , vol.23 , Issue.24 , pp. 8480-8488
    • Moron, J.A.1    Zakharova, I.2    Ferrer, J.V.3    Merrill, G.A.4    Hope, B.5    Lafer, E.M.6
  • 85
    • 38849191834 scopus 로고    scopus 로고
    • Standard protecting groups create potent and selective kappa opioids: Salvinorin B alkoxymethyl ethers
    • Munro T.A., Duncan K.K., Xu W., Wang Y., Liu-Chen L.-Y., Carlezon W.A., et al. Standard protecting groups create potent and selective kappa opioids: Salvinorin B alkoxymethyl ethers. Bioorganic & Medicinal Chemistry 2008, 16(3):1279-1286.
    • (2008) Bioorganic & Medicinal Chemistry , vol.16 , Issue.3 , pp. 1279-1286
    • Munro, T.A.1    Duncan, K.K.2    Xu, W.3    Wang, Y.4    Liu-Chen, L.-Y.5    Carlezon, W.A.6
  • 86
    • 12344326698 scopus 로고    scopus 로고
    • Studies toward the pharmacophore of salvinorin A, a potent kappa opioid receptor agonist
    • Munro T.A., Rizzacasa M.A., Roth B.L., Toth B.A., Yan F. Studies toward the pharmacophore of salvinorin A, a potent kappa opioid receptor agonist. Journal of Medicinal Chemistry 2005, 48(2):345-348.
    • (2005) Journal of Medicinal Chemistry , vol.48 , Issue.2 , pp. 345-348
    • Munro, T.A.1    Rizzacasa, M.A.2    Roth, B.L.3    Toth, B.A.4    Yan, F.5
  • 87
  • 88
    • 79961202746 scopus 로고    scopus 로고
    • Tracking down the molecular substrates of stress: New roles for p38alpha MAPK and kappa-opioid receptors
    • Muschamp J.W., Van't Veer A., Carlezon W.A. Tracking down the molecular substrates of stress: New roles for p38alpha MAPK and kappa-opioid receptors. Neuron 2011, 71(3):383-385.
    • (2011) Neuron , vol.71 , Issue.3 , pp. 383-385
    • Muschamp, J.W.1    Van't Veer, A.2    Carlezon, W.A.3
  • 90
    • 0035260641 scopus 로고    scopus 로고
    • Molecular basis of long-term plasticity underlying addiction
    • Nestler E.J. Molecular basis of long-term plasticity underlying addiction. Nature Reviews. Neuroscience 2001, 2(2):119-128.
    • (2001) Nature Reviews. Neuroscience , vol.2 , Issue.2 , pp. 119-128
    • Nestler, E.J.1
  • 91
    • 33746900423 scopus 로고    scopus 로고
    • The mesolimbic dopamine reward circuit in depression
    • Nestler E.J., Carlezon W.A. The mesolimbic dopamine reward circuit in depression. Biological Psychiatry 2006, 59(12):1151-1159.
    • (2006) Biological Psychiatry , vol.59 , Issue.12 , pp. 1151-1159
    • Nestler, E.J.1    Carlezon, W.A.2
  • 92
    • 0030766244 scopus 로고    scopus 로고
    • The dopamine transporter: Comparative ultrastructure of dopaminergic axons in limbic and motor compartments of the nucleus accumbens
    • Nirenberg M.J., Chan J., Pohorille A., Vaughan R.A., Uhl G.R., Kuhar M.J., et al. The dopamine transporter: Comparative ultrastructure of dopaminergic axons in limbic and motor compartments of the nucleus accumbens. The Journal of Neuroscience 1997, 17:6899-6907.
    • (1997) The Journal of Neuroscience , vol.17 , pp. 6899-6907
    • Nirenberg, M.J.1    Chan, J.2    Pohorille, A.3    Vaughan, R.A.4    Uhl, G.R.5    Kuhar, M.J.6
  • 94
    • 80051932728 scopus 로고    scopus 로고
    • Salvinorin B derivatives, EOM-Sal B and MOM-Sal B, produce stimulus generalization in male Sprague-Dawley rats trained to discriminate salvinorin A
    • Peet M.M., Baker L.E. Salvinorin B derivatives, EOM-Sal B and MOM-Sal B, produce stimulus generalization in male Sprague-Dawley rats trained to discriminate salvinorin A. Behavioural Pharmacology 2011, 22(5-6):450-457.
    • (2011) Behavioural Pharmacology , vol.22 , Issue.5-6 , pp. 450-457
    • Peet, M.M.1    Baker, L.E.2
  • 95
    • 34848816806 scopus 로고    scopus 로고
    • Cotreatment with the kappa opioid agonist U69593 enhances locomotor sensitization to the D2/D3 dopamine agonist quinpirole and alters dopamine D2 receptor and prodynorphin mRNA expression in rats
    • Perreault M.L., Graham D., Scattolon S., Wang Y., Szechtman H., Foster J.A. Cotreatment with the kappa opioid agonist U69593 enhances locomotor sensitization to the D2/D3 dopamine agonist quinpirole and alters dopamine D2 receptor and prodynorphin mRNA expression in rats. Psychopharmacology 2007, 194(4):485-496.
    • (2007) Psychopharmacology , vol.194 , Issue.4 , pp. 485-496
    • Perreault, M.L.1    Graham, D.2    Scattolon, S.3    Wang, Y.4    Szechtman, H.5    Foster, J.A.6
  • 96
    • 0022494591 scopus 로고
    • Psychotomimesis mediated by kappa-opiate receptors
    • Pfeiffer A., Brantl V., Herz A., Emrich H.M. Psychotomimesis mediated by kappa-opiate receptors. Science 1986, 233(4765):774-776.
    • (1986) Science , vol.233 , Issue.4765 , pp. 774-776
    • Pfeiffer, A.1    Brantl, V.2    Herz, A.3    Emrich, H.M.4
  • 98
    • 0035884949 scopus 로고    scopus 로고
    • Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens
    • Pliakas A.M., Carlson R.R., Neve R.L., Konradi C., Nestler E.J., Carlezon W.A. Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens. The Journal of Neuroscience 2001, 21(18):7397-7403.
    • (2001) The Journal of Neuroscience , vol.21 , Issue.18 , pp. 7397-7403
    • Pliakas, A.M.1    Carlson, R.R.2    Neve, R.L.3    Konradi, C.4    Nestler, E.J.5    Carlezon, W.A.6
  • 99
    • 0018763594 scopus 로고
    • Animal-model of depression
    • Porsolt R.D. Animal-model of depression. Biomedicine 1979, 30(3):139-140.
    • (1979) Biomedicine , vol.30 , Issue.3 , pp. 139-140
    • Porsolt, R.D.1
  • 100
    • 80053562267 scopus 로고    scopus 로고
    • Repeated exposure to the kappa-opioid receptor agonist salvinorin A modulates extracellular signal-regulated kinase and reward sensitivity
    • Potter D.N., Damez-Werno D., Carlezon W.A., Cohen B.M., Chartoff E.H. Repeated exposure to the kappa-opioid receptor agonist salvinorin A modulates extracellular signal-regulated kinase and reward sensitivity. Biological Psychiatry 2011, 70(8):744-753.
    • (2011) Biological Psychiatry , vol.70 , Issue.8 , pp. 744-753
    • Potter, D.N.1    Damez-Werno, D.2    Carlezon, W.A.3    Cohen, B.M.4    Chartoff, E.H.5
  • 102
    • 65349086382 scopus 로고    scopus 로고
    • Natural products as tools for neuroscience: Discovery and development of novel agents to treat drug abuse
    • Prisinzano T.E. Natural products as tools for neuroscience: Discovery and development of novel agents to treat drug abuse. Journal of Natural Products 2009, 72(3):581-587.
    • (2009) Journal of Natural Products , vol.72 , Issue.3 , pp. 581-587
    • Prisinzano, T.E.1
  • 103
    • 44849121317 scopus 로고    scopus 로고
    • Salvinorin A analogs as probes in opioid pharmacology
    • Prisinzano T.E., Rothman R.B. Salvinorin A analogs as probes in opioid pharmacology. Chemical Reviews 2008, 108(5):1732-1743.
    • (2008) Chemical Reviews , vol.108 , Issue.5 , pp. 1732-1743
    • Prisinzano, T.E.1    Rothman, R.B.2
  • 104
    • 33646661816 scopus 로고    scopus 로고
    • Kappa opioids as potential treatments for stimulant dependence
    • Prisinzano T.E., Tidgewell K., Harding W.W. Kappa opioids as potential treatments for stimulant dependence. AAPS Journal 2005, 7(3):E592-E599.
    • (2005) AAPS Journal , vol.7 , Issue.3
    • Prisinzano, T.E.1    Tidgewell, K.2    Harding, W.W.3
  • 105
    • 84867746318 scopus 로고    scopus 로고
    • Dose-related behavioral, subjective, endocrine, and psychophysiological effects of the kappa opioid agonist salvinorin A in humans
    • Ranganathan M., Schnakenberg A., Skosnik P.D., Cohen B.M., Pittman B., Sewell R.A., et al. Dose-related behavioral, subjective, endocrine, and psychophysiological effects of the kappa opioid agonist salvinorin A in humans. Biological Psychiatry 2012, 72(10):871-879.
    • (2012) Biological Psychiatry , vol.72 , Issue.10 , pp. 871-879
    • Ranganathan, M.1    Schnakenberg, A.2    Skosnik, P.D.3    Cohen, B.M.4    Pittman, B.5    Sewell, R.A.6
  • 106
    • 0027381129 scopus 로고
    • Interacting presynaptic kappa-opioid and GABAA receptors modulate dopamine release from rat striatal synaptosomes
    • Ronken E., Mulder A.H., Schoffelmeer A.N. Interacting presynaptic kappa-opioid and GABAA receptors modulate dopamine release from rat striatal synaptosomes. Journal of Neurochemistry 1993, 61(5):1634-1639.
    • (1993) Journal of Neurochemistry , vol.61 , Issue.5 , pp. 1634-1639
    • Ronken, E.1    Mulder, A.H.2    Schoffelmeer, A.N.3
  • 108
    • 0037086830 scopus 로고    scopus 로고
    • Studies of the biogenic amine transporters. VIII: Identification of a novel partial inhibitor of dopamine uptake and dopamine transporter binding
    • Rothman R.B., Dersch C.M., Carroll F.I., Ananthan S. Studies of the biogenic amine transporters. VIII: Identification of a novel partial inhibitor of dopamine uptake and dopamine transporter binding. Synapse 2002, 43(4):268-274.
    • (2002) Synapse , vol.43 , Issue.4 , pp. 268-274
    • Rothman, R.B.1    Dersch, C.M.2    Carroll, F.I.3    Ananthan, S.4
  • 110
  • 112
    • 0032982427 scopus 로고    scopus 로고
    • U69593, a kappa-opioid agonist, decreases cocaine self-administration and decreases cocaine-produced drug-seeking
    • Schenk S., Partridge B., Shippenberg T.S. U69593, a kappa-opioid agonist, decreases cocaine self-administration and decreases cocaine-produced drug-seeking. Psychopharmacology 1999, 144(4):339-346.
    • (1999) Psychopharmacology , vol.144 , Issue.4 , pp. 339-346
    • Schenk, S.1    Partridge, B.2    Shippenberg, T.S.3
  • 113
    • 26644453330 scopus 로고    scopus 로고
    • Pharmacokinetics of the plant-derived kappa-opioid hallucinogen salvinorin A in nonhuman primates
    • Schmidt M.D., Schmidt M.S., Butelman E.R., Harding W.W., Tidgewell K., Murry D.J., et al. Pharmacokinetics of the plant-derived kappa-opioid hallucinogen salvinorin A in nonhuman primates. Synapse 2005, 58(3):208-210.
    • (2005) Synapse , vol.58 , Issue.3 , pp. 208-210
    • Schmidt, M.D.1    Schmidt, M.S.2    Butelman, E.R.3    Harding, W.W.4    Tidgewell, K.5    Murry, D.J.6
  • 114
    • 57649128341 scopus 로고    scopus 로고
    • The dynorphin/kappa opioid receptor system: A new target for the treatment of addiction and affective disorders?
    • Shippenberg T.S. The dynorphin/kappa opioid receptor system: A new target for the treatment of addiction and affective disorders?. Neuropsychopharmacology 2009, 34(1):247.
    • (2009) Neuropsychopharmacology , vol.34 , Issue.1 , pp. 247
    • Shippenberg, T.S.1
  • 115
    • 0027521734 scopus 로고
    • Examination of the neurochemical substrates mediating the motivational effects of opioids-Role of the mesolimbic dopamine system and D-1 vs D-2 dopamine-receptors
    • Shippenberg T.S., Balskubik R., Herz A. Examination of the neurochemical substrates mediating the motivational effects of opioids-Role of the mesolimbic dopamine system and D-1 vs D-2 dopamine-receptors. Journal of Pharmacology and Experimental Therapeutics 1993, 265(1):53-59.
    • (1993) Journal of Pharmacology and Experimental Therapeutics , vol.265 , Issue.1 , pp. 53-59
    • Shippenberg, T.S.1    Balskubik, R.2    Herz, A.3
  • 116
    • 0026030156 scopus 로고
    • Neuroanatomical substrates mediating the aversive effects of D-1 dopamine receptor antagonists
    • Shippenberg T.S., Bals-Kubik R., Huber A., Herz A. Neuroanatomical substrates mediating the aversive effects of D-1 dopamine receptor antagonists. Psychopharmacology 1991, 103(2):209-214.
    • (1991) Psychopharmacology , vol.103 , Issue.2 , pp. 209-214
    • Shippenberg, T.S.1    Bals-Kubik, R.2    Huber, A.3    Herz, A.4
  • 118
    • 0023619127 scopus 로고
    • Place preference conditioning reveals the involvement of D1-dopamine receptors in the motivational properties of mu- and kappa-opioid agonists
    • Shippenberg T.S., Herz A. Place preference conditioning reveals the involvement of D1-dopamine receptors in the motivational properties of mu- and kappa-opioid agonists. Brain Research 1987, 436(1):169-172.
    • (1987) Brain Research , vol.436 , Issue.1 , pp. 169-172
    • Shippenberg, T.S.1    Herz, A.2
  • 119
    • 0023793488 scopus 로고
    • Motivational effects of opioids: Influence of D-1 versus D-2 receptor antagonists
    • Shippenberg T.S., Herz A. Motivational effects of opioids: Influence of D-1 versus D-2 receptor antagonists. European Journal of Pharmacology 1988, 151(2):233-242.
    • (1988) European Journal of Pharmacology , vol.151 , Issue.2 , pp. 233-242
    • Shippenberg, T.S.1    Herz, A.2
  • 121
    • 4444332549 scopus 로고    scopus 로고
    • Stress increases dynorphin immunoreactivity in limbic brain regions and dynorphin antagonism produces antidepressant-like effects
    • Shirayama Y., Ishida H., Iwata M., Hazama G.I., Kawahara R., Duman R.S. Stress increases dynorphin immunoreactivity in limbic brain regions and dynorphin antagonism produces antidepressant-like effects. Journal of Neurochemistry 2004, 90(5):1258-1268.
    • (2004) Journal of Neurochemistry , vol.90 , Issue.5 , pp. 1258-1268
    • Shirayama, Y.1    Ishida, H.2    Iwata, M.3    Hazama, G.I.4    Kawahara, R.5    Duman, R.S.6
  • 122
    • 0028305754 scopus 로고
    • Salvia-divinorum and salvinorin-A-New pharmacological findings
    • Siebert D.J. Salvia-divinorum and salvinorin-A-New pharmacological findings. Journal of Ethnopharmacology 1994, 43(1):53-56.
    • (1994) Journal of Ethnopharmacology , vol.43 , Issue.1 , pp. 53-56
    • Siebert, D.J.1
  • 123
    • 0028983787 scopus 로고
    • Kappa-opioid receptor in humans: cDNA and genomic cloning, chromosomal assignment, functional expression, pharmacology, and expression pattern in the central nervous system
    • Simonin F., Gaveriaux-Ruff C., Befort K., Matthes H., Lannes B., Micheletti G., et al. Kappa-opioid receptor in humans: cDNA and genomic cloning, chromosomal assignment, functional expression, pharmacology, and expression pattern in the central nervous system. Proceedings of the National Academy of Sciences 1995, 92(15):7006-7010.
    • (1995) Proceedings of the National Academy of Sciences , vol.92 , Issue.15 , pp. 7006-7010
    • Simonin, F.1    Gaveriaux-Ruff, C.2    Befort, K.3    Matthes, H.4    Lannes, B.5    Micheletti, G.6
  • 124
    • 0024462220 scopus 로고
    • Cocaine selectively increases striatonigral dynorphin levels by a dopaminergic mechanism
    • Sivam S.P. Cocaine selectively increases striatonigral dynorphin levels by a dopaminergic mechanism. Journal of Pharmacology and Experimental Therapeutics 1989, 250(3):818-824.
    • (1989) Journal of Pharmacology and Experimental Therapeutics , vol.250 , Issue.3 , pp. 818-824
    • Sivam, S.P.1
  • 127
    • 0027327238 scopus 로고
    • 'Binge' cocaine administration induces a sustained increase of prodynorphin mRNA in rat caudate-putamen
    • Spangler R., Unterwald E.M., Kreek M.J. 'Binge' cocaine administration induces a sustained increase of prodynorphin mRNA in rat caudate-putamen. Molecular Brain Research 1993, 19(4):323-327.
    • (1993) Molecular Brain Research , vol.19 , Issue.4 , pp. 323-327
    • Spangler, R.1    Unterwald, E.M.2    Kreek, M.J.3
  • 129
    • 0023762601 scopus 로고
    • Body temperature response profiles for selective mu, delta and kappa opioid agonists in restrained and unrestrained rats
    • Spencer R., Hruby V., Burks T. Body temperature response profiles for selective mu, delta and kappa opioid agonists in restrained and unrestrained rats. Journal of Pharmacology and Experimental Therapeutics 1988, 246(1):92-101.
    • (1988) Journal of Pharmacology and Experimental Therapeutics , vol.246 , Issue.1 , pp. 92-101
    • Spencer, R.1    Hruby, V.2    Burks, T.3
  • 130
    • 79251638019 scopus 로고    scopus 로고
    • Salvinorin A produces cerebrovasodilation through activation of nitric oxide synthase, κ receptor, and adenosine triphosphate-sensitive potassium channel
    • Su D., Riley J., Kiessling W.J., Armstead W.M., Liu R. Salvinorin A produces cerebrovasodilation through activation of nitric oxide synthase, κ receptor, and adenosine triphosphate-sensitive potassium channel. Anesthesiology 2011, 114(2):374.
    • (2011) Anesthesiology , vol.114 , Issue.2 , pp. 374
    • Su, D.1    Riley, J.2    Kiessling, W.J.3    Armstead, W.M.4    Liu, R.5
  • 132
    • 0035889678 scopus 로고    scopus 로고
    • Major coexpression of kappa-opioid receptors and the dopamine transporter in nucleus accumbens axonal profiles
    • Svingos A.L., Chavkin C., Colago E.E., Pickel V.M. Major coexpression of kappa-opioid receptors and the dopamine transporter in nucleus accumbens axonal profiles. Synapse 2001, 42(3):185-192.
    • (2001) Synapse , vol.42 , Issue.3 , pp. 185-192
    • Svingos, A.L.1    Chavkin, C.2    Colago, E.E.3    Pickel, V.M.4
  • 133
    • 0021915777 scopus 로고
    • Behavioral-effects of a novel kappa-opioid analgesic, U-50488, in rats and rhesus-monkeys
    • Tang A.H., Collins R.J. Behavioral-effects of a novel kappa-opioid analgesic, U-50488, in rats and rhesus-monkeys. Psychopharmacology 1985, 85(3):309-314.
    • (1985) Psychopharmacology , vol.85 , Issue.3 , pp. 309-314
    • Tang, A.H.1    Collins, R.J.2
  • 134
    • 0036827560 scopus 로고    scopus 로고
    • Opioid receptor subtypes differentially modulate serotonin efflux in the rat central nervous system
    • Tao R., Auerbach S.B. Opioid receptor subtypes differentially modulate serotonin efflux in the rat central nervous system. Journal of Pharmacology and Experimental Therapeutics 2002, 303(2):549-556.
    • (2002) Journal of Pharmacology and Experimental Therapeutics , vol.303 , Issue.2 , pp. 549-556
    • Tao, R.1    Auerbach, S.B.2
  • 135
    • 20444507161 scopus 로고    scopus 로고
    • Mu-opioids disinhibit and kappa-opioids inhibit serotonin efflux in the dorsal raphe nucleus
    • Tao R., Auerbach S.B. Mu-opioids disinhibit and kappa-opioids inhibit serotonin efflux in the dorsal raphe nucleus. Brain Research 2005, 1049(1):70-79.
    • (2005) Brain Research , vol.1049 , Issue.1 , pp. 70-79
    • Tao, R.1    Auerbach, S.B.2
  • 137
    • 0034671384 scopus 로고    scopus 로고
    • Kappa-opioid receptor activation modifies dopamine uptake in the nucleus accumbens and opposes the effects of cocaine
    • Thompson A.C., Zapata A., Justice J.B., Vaughan R.A., Sharpe L.G., Shippenberg T.S. Kappa-opioid receptor activation modifies dopamine uptake in the nucleus accumbens and opposes the effects of cocaine. Journal of Neuroscience 2000, 20(24):9333-9340.
    • (2000) Journal of Neuroscience , vol.20 , Issue.24 , pp. 9333-9340
    • Thompson, A.C.1    Zapata, A.2    Justice, J.B.3    Vaughan, R.A.4    Sharpe, L.G.5    Shippenberg, T.S.6
  • 139
    • 0030571615 scopus 로고    scopus 로고
    • Delayed occurrence of enhanced striatal preprodynorphin gene expression in behaviorally sensitized rats: Differential long-term effects of intermittent and chronic morphine administration
    • Tjon G.H.K., Voorn P., Vanderschuren L., DeVries T.J., Michiels N., Jonker A.J., et al. Delayed occurrence of enhanced striatal preprodynorphin gene expression in behaviorally sensitized rats: Differential long-term effects of intermittent and chronic morphine administration. Neuroscience 1997, 76(1):167-176.
    • (1997) Neuroscience , vol.76 , Issue.1 , pp. 167-176
    • Tjon, G.H.K.1    Voorn, P.2    Vanderschuren, L.3    DeVries, T.J.4    Michiels, N.5    Jonker, A.J.6
  • 140
    • 2442628167 scopus 로고    scopus 로고
    • Effects of kappa-opioid receptor ligands on intracranial self-stimulation in rats
    • Todtenkopf M.S., Marcus J.F., Portoghese P.S., Carlezon W.A. Effects of kappa-opioid receptor ligands on intracranial self-stimulation in rats. Psychopharmacology 2004, 172(4):463-470.
    • (2004) Psychopharmacology , vol.172 , Issue.4 , pp. 463-470
    • Todtenkopf, M.S.1    Marcus, J.F.2    Portoghese, P.S.3    Carlezon, W.A.4
  • 141
    • 84884554332 scopus 로고    scopus 로고
    • Kappa-opioid receptor signaling in the striatum as a potential modulator of dopamine transmission in cocaine dependence
    • Trifilieff P., Martinez D. Kappa-opioid receptor signaling in the striatum as a potential modulator of dopamine transmission in cocaine dependence. Frontiers in Psychiatry 2013, 4.
    • (2013) Frontiers in Psychiatry , vol.4
    • Trifilieff, P.1    Martinez, D.2
  • 142
    • 0035840301 scopus 로고    scopus 로고
    • Kappa opioid receptor stimulation decreases amphetamine-induced behavior and neuropeptide mRNA expression in the striatum
    • Tzaferis J.A., McGinty J.F. Kappa opioid receptor stimulation decreases amphetamine-induced behavior and neuropeptide mRNA expression in the striatum. Molecular Brain Research 2001, 93(1):27-35.
    • (2001) Molecular Brain Research , vol.93 , Issue.1 , pp. 27-35
    • Tzaferis, J.A.1    McGinty, J.F.2
  • 143
    • 0028110978 scopus 로고
    • Repeated cocaine administration upregulates K and [mu], but not [delta], opioid receptors
    • Unterwald E.M., Rubenfeld J.M., Kreek M.J. Repeated cocaine administration upregulates K and [mu], but not [delta], opioid receptors. Neuroreport 1994, 5(13):1613-1616.
    • (1994) Neuroreport , vol.5 , Issue.13 , pp. 1613-1616
    • Unterwald, E.M.1    Rubenfeld, J.M.2    Kreek, M.J.3
  • 144
    • 0035969605 scopus 로고    scopus 로고
    • Salvinorin C, a new neoclerodane diterpene from a bioactive fraction of the hallucinogenic Mexican mint Salvia divinorum
    • Valdes L.J., Chang H.M., Visger D.C., Koreeda M. Salvinorin C, a new neoclerodane diterpene from a bioactive fraction of the hallucinogenic Mexican mint Salvia divinorum. Organic Letters 2001, 3(24):3935-3937.
    • (2001) Organic Letters , vol.3 , Issue.24 , pp. 3935-3937
    • Valdes, L.J.1    Chang, H.M.2    Visger, D.C.3    Koreeda, M.4
  • 145
    • 84884286533 scopus 로고    scopus 로고
    • Role of kappa-opioid receptors in stress and anxiety-related behavior
    • Van't Veer A., Carlezon W.A. Role of kappa-opioid receptors in stress and anxiety-related behavior. Psychopharmacology 2013, 1-18.
    • (2013) Psychopharmacology
    • Van't Veer, A.1    Carlezon, W.A.2
  • 146
    • 33749671701 scopus 로고    scopus 로고
    • Salvinorin A: From natural product to human therapeutics
    • Vortherms T.A., Roth B.L. Salvinorin A: From natural product to human therapeutics. Molecular Interventions 2006, 6(5):257-265.
    • (2006) Molecular Interventions , vol.6 , Issue.5 , pp. 257-265
    • Vortherms, T.A.1    Roth, B.L.2
  • 147
    • 77953289824 scopus 로고    scopus 로고
    • Kappa opioid mediation of cannabinoid effects of the potent hallucinogen, salvinorin A, in rodents
    • Walentiny D.M., Vann R.E., Warner J.A., King L.S., Seltzman H.H., Navarro H.A., et al. Kappa opioid mediation of cannabinoid effects of the potent hallucinogen, salvinorin A, in rodents. Psychopharmacology 2010, 210(2):275-284.
    • (2010) Psychopharmacology , vol.210 , Issue.2 , pp. 275-284
    • Walentiny, D.M.1    Vann, R.E.2    Warner, J.A.3    King, L.S.4    Seltzman, H.H.5    Navarro, H.A.6
  • 148
    • 78649910013 scopus 로고    scopus 로고
    • Systemic kappa-opioid receptor antagonism by nor-binaltorphimine reduces dependence-induced excessive alcohol self-administration in rats
    • Walker B.M., Zorrilla E.P., Koob G.F. Systemic kappa-opioid receptor antagonism by nor-binaltorphimine reduces dependence-induced excessive alcohol self-administration in rats. Addiction Biology 2010, 16:116-119.
    • (2010) Addiction Biology , vol.16 , pp. 116-119
    • Walker, B.M.1    Zorrilla, E.P.2    Koob, G.F.3
  • 149
    • 0034807831 scopus 로고    scopus 로고
    • Enadoline and butorphanol: Evaluation of kappa-agonists on cocaine pharmacodynamics and cocaine self-administration in humans
    • Walsh S.L., Geter-Douglas B., Strain E.C., Bigelow G.E. Enadoline and butorphanol: Evaluation of kappa-agonists on cocaine pharmacodynamics and cocaine self-administration in humans. Journal of Pharmacology and Experimental Therapeutics 2001, 299(1):147-158.
    • (2001) Journal of Pharmacology and Experimental Therapeutics , vol.299 , Issue.1 , pp. 147-158
    • Walsh, S.L.1    Geter-Douglas, B.2    Strain, E.C.3    Bigelow, G.E.4
  • 150
    • 0034873586 scopus 로고    scopus 로고
    • Enadoline, a selective kappa opioid agonist: Comparison with butorphanol and hydromorphone in humans
    • Walsh S.L., Strain E.C., Abreu M.E., Bigelow G.E. Enadoline, a selective kappa opioid agonist: Comparison with butorphanol and hydromorphone in humans. Psychopharmacology 2001, 157(2):151-162.
    • (2001) Psychopharmacology , vol.157 , Issue.2 , pp. 151-162
    • Walsh, S.L.1    Strain, E.C.2    Abreu, M.E.3    Bigelow, G.E.4
  • 151
    • 40849124258 scopus 로고    scopus 로고
    • 2-Methoxymethyl-salvinorin B is a potent kappa opioid receptor agonist with longer lasting action in vivo than salvinorin A
    • Wang Y., Chen Y., Xu W., Lee D.Y.W., Ma Z., Rawls S.M., et al. 2-Methoxymethyl-salvinorin B is a potent kappa opioid receptor agonist with longer lasting action in vivo than salvinorin A. Journal of Pharmacology and Experimental Therapeutics 2008, 324(3):1073-1083.
    • (2008) Journal of Pharmacology and Experimental Therapeutics , vol.324 , Issue.3 , pp. 1073-1083
    • Wang, Y.1    Chen, Y.2    Xu, W.3    Lee, D.Y.W.4    Ma, Z.5    Rawls, S.M.6
  • 152
    • 84864238294 scopus 로고    scopus 로고
    • Salvinorin A administration after global cerebral hypoxia/ischemia preserves cerebrovascular autoregulation via kappa opioid receptor in piglets
    • Wang Z., Ma N., Riley J., Armstead W.M., Liu R. Salvinorin A administration after global cerebral hypoxia/ischemia preserves cerebrovascular autoregulation via kappa opioid receptor in piglets. PLoS ONE 2012, 7(7):e41724.
    • (2012) PLoS ONE , vol.7 , Issue.7
    • Wang, Z.1    Ma, N.2    Riley, J.3    Armstead, W.M.4    Liu, R.5
  • 153
    • 77956358093 scopus 로고    scopus 로고
    • The role of kappa-opioid receptor activation in mediating antinociception and addiction
    • Wang Y.H., Sun J.F., Tao Y.M., Chi Z.Q., Liu J.G. The role of kappa-opioid receptor activation in mediating antinociception and addiction. Acta Pharmacologica Sinica 2010, 31(9):1065-1070.
    • (2010) Acta Pharmacologica Sinica , vol.31 , Issue.9 , pp. 1065-1070
    • Wang, Y.H.1    Sun, J.F.2    Tao, Y.M.3    Chi, Z.Q.4    Liu, J.G.5
  • 154
    • 0033586358 scopus 로고    scopus 로고
    • Acute intermittent morphine increases preprodynorphin and kappa opioid receptor mRNA levels in the rat brain
    • Wang X.M., Zhou Y., Spangler R., Ho A., Han J.S., Kreek M.J. Acute intermittent morphine increases preprodynorphin and kappa opioid receptor mRNA levels in the rat brain. Molecular Brain Research 1999, 66(1-2):184-187.
    • (1999) Molecular Brain Research , vol.66 , Issue.1-2 , pp. 184-187
    • Wang, X.M.1    Zhou, Y.2    Spangler, R.3    Ho, A.4    Han, J.S.5    Kreek, M.J.6
  • 155
    • 0020393409 scopus 로고
    • Dynorphin is located throughout the CNS and is often co-localized with alpha-neo-endorphin
    • 16-1
    • Watson S.J., Khachaturian H., Coy D., Taylor L., Akil H. Dynorphin is located throughout the CNS and is often co-localized with alpha-neo-endorphin. Life Sciences 1982, 31(16-1):1773-1776.
    • (1982) Life Sciences , vol.31 , pp. 1773-1776
    • Watson, S.J.1    Khachaturian, H.2    Coy, D.3    Taylor, L.4    Akil, H.5
  • 156
    • 77953290684 scopus 로고    scopus 로고
    • The role of the dynorphin-kappa opioid system in the reinforcing effects of drugs of abuse
    • Wee S., Koob G.F. The role of the dynorphin-kappa opioid system in the reinforcing effects of drugs of abuse. Psychopharmacology 2010, 210(2):121-135.
    • (2010) Psychopharmacology , vol.210 , Issue.2 , pp. 121-135
    • Wee, S.1    Koob, G.F.2
  • 157
    • 68149166916 scopus 로고    scopus 로고
    • Inhibition of kappa opioid receptors attenuated increased cocaine intake in rats with extended access to cocaine
    • Wee S., Orio L., Ghirmai S., Cashman J.R., Koob G.F. Inhibition of kappa opioid receptors attenuated increased cocaine intake in rats with extended access to cocaine. Psychopharmacology 2009, 205:565-575.
    • (2009) Psychopharmacology , vol.205 , pp. 565-575
    • Wee, S.1    Orio, L.2    Ghirmai, S.3    Cashman, J.R.4    Koob, G.F.5
  • 158
    • 0026663188 scopus 로고
    • Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration
    • Weiss F., Markou A., Lorang M.T., Koob G.F. Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration. Brain Research 1992, 593(2):314-318.
    • (1992) Brain Research , vol.593 , Issue.2 , pp. 314-318
    • Weiss, F.1    Markou, A.2    Lorang, M.T.3    Koob, G.F.4
  • 160
    • 0021882377 scopus 로고
    • Comparison of fixed-ratio and progressive-ratio schedules of maintenance of stimulant drug-reinforced responding
    • Winger G., Woods J.H. Comparison of fixed-ratio and progressive-ratio schedules of maintenance of stimulant drug-reinforced responding. Drug and Alcohol Dependence 1985, 15(1-2):123-130.
    • (1985) Drug and Alcohol Dependence , vol.15 , Issue.1-2 , pp. 123-130
    • Winger, G.1    Woods, J.H.2
  • 161
    • 0032104560 scopus 로고    scopus 로고
    • Drug-activation of brain reward pathways
    • Wise R.A. Drug-activation of brain reward pathways. Drug and Alcohol Dependence 1998, 51(1-2):13-22.
    • (1998) Drug and Alcohol Dependence , vol.51 , Issue.1-2 , pp. 13-22
    • Wise, R.A.1
  • 163
    • 79960958495 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinase is critical for the discriminative stimulus effects induced by U-50,488H
    • Yoshizawa K., Narita M., Saeki M., Narita M., Isotani K., Horiuchi H., et al. Activation of extracellular signal-regulated kinase is critical for the discriminative stimulus effects induced by U-50,488H. Synapse 2011, 65(10):1052-1061.
    • (2011) Synapse , vol.65 , Issue.10 , pp. 1052-1061
    • Yoshizawa, K.1    Narita, M.2    Saeki, M.3    Narita, M.4    Isotani, K.5    Horiuchi, H.6
  • 164
    • 2442488532 scopus 로고    scopus 로고
    • Effect of the endogenous kappa opioid agonist dynorphin A(1-17) on cocaine-evoked increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice
    • Zhang Y., Butelman E.R., Schlussman S.D., Ho A., Kreek M.J. Effect of the endogenous kappa opioid agonist dynorphin A(1-17) on cocaine-evoked increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice. Psychopharmacology 2004, 172(4):422-429.
    • (2004) Psychopharmacology , vol.172 , Issue.4 , pp. 422-429
    • Zhang, Y.1    Butelman, E.R.2    Schlussman, S.D.3    Ho, A.4    Kreek, M.J.5
  • 165
    • 18744387407 scopus 로고    scopus 로고
    • Effects of the plant-derived hallucinogen salvinorin A on basal dopamine levels in the caudate putamen and in a conditioned place aversion assay in mice: Agonist actions at kappa opioid receptors
    • Zhang Y., Butelman E.R., Schlussman S.D., Ho A., Kreek M.J. Effects of the plant-derived hallucinogen salvinorin A on basal dopamine levels in the caudate putamen and in a conditioned place aversion assay in mice: Agonist actions at kappa opioid receptors. Psychopharmacology 2005, 179(3):551-558.
    • (2005) Psychopharmacology , vol.179 , Issue.3 , pp. 551-558
    • Zhang, Y.1    Butelman, E.R.2    Schlussman, S.D.3    Ho, A.4    Kreek, M.J.5
  • 166
    • 84873337146 scopus 로고    scopus 로고
    • Chronic escalating cocaine exposure, abstinence/withdrawal, and chronic re-exposure: Effects on striatal dopamine and opioid systems in C57BL/6J mice
    • Zhang Y., Schlussman S.D., Rabkin J., Butelman E.R., Ho A., Kreek M.J. Chronic escalating cocaine exposure, abstinence/withdrawal, and chronic re-exposure: Effects on striatal dopamine and opioid systems in C57BL/6J mice. Neuropharmacology 2013, 67:259-266.
    • (2013) Neuropharmacology , vol.67 , pp. 259-266
    • Zhang, Y.1    Schlussman, S.D.2    Rabkin, J.3    Butelman, E.R.4    Ho, A.5    Kreek, M.J.6
  • 167
    • 34547841507 scopus 로고    scopus 로고
    • Central kappa-opioid receptor-mediated antidepressant-like effects of nor-Binaltorphimine: Behavioral and BDNF mRNA expression studies
    • Zhang H., Shi Y.G., Woods J.H., Watson S.J., Ko M.C. Central kappa-opioid receptor-mediated antidepressant-like effects of nor-Binaltorphimine: Behavioral and BDNF mRNA expression studies. European Journal of Pharmacology 2007, 570(1-3):89-96.
    • (2007) European Journal of Pharmacology , vol.570 , Issue.1-3 , pp. 89-96
    • Zhang, H.1    Shi, Y.G.2    Woods, J.H.3    Watson, S.J.4    Ko, M.C.5


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