Drug-activation of brain reward pathways

Drug and Alcohol Dependence

Volumn 51, Issue 1-2, 1998, Pages 13-22

  Wise, Roy A ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHETAMINE; DOPAMINE; NEUROTRANSMITTER; OPIATE; PHENCYCLIDINE; PSYCHOTROPIC AGENT;

ADAPTATION; DOPAMINERGIC NERVE CELL; DRUG DEPENDENCE; ELECTROSTIMULATION; EVOLUTION; FOREBRAIN; HUMAN; NERVE FIBER; NERVE PROJECTION; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PRIORITY JOURNAL; REVIEW; REWARD;

EID: 0032104560     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0376-8716(98)00063-5     Document Type: Article

References (115)

1. Aghajanian, G.K., 1978. Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine. Nature 276, 186-188.
2. Alexander, G.E., Crutcher, M.D., 1990. Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends Neurosci. 13, 266-271.
3. Bauco, P., Rivest, R., Wise, R.A., 1994. Extracellular nucleus accumbens dopamine and metabolite levels during earned and unearned lateral hypothalamic brain stimulation. Soc. Neurosci. Abstr. 20, 823.
4. Bauco, P., Wise, R., 1994. Potentiation of lateral hypothalamic and midline mesencephalic brain stimulation reinforcement by nicotine: Examination of repeated treatment. J. Pharmacol. Exp. Ther. 271, 294-301.
5. Bielajew, C., Shizgal, P., 1982. Behaviorally derived measures of conduction velocity in the substrate for rewarding medial forebrain bundle stimulation. Brain Res. 237, 107-119.
6. Bielajew, C., Shizgal, P., 1986. Evidence implicating descending fibers in self-stimulation of the medial forebrain bundle. J. Neurosci. 6, 919-929.
7. Bozarth, M.A., Wise, R.A., 1981. Intracranial self-administration of morphine into the ventral tegmental area in rats. Life Sci. 28, 551-555.
8. Britt, M.D., Wise, R.A., 1981. Opiate Rewarding Action: Independence of the Cells of the Lateral Hypothalamus, 222, pp. 213-217.
9. Carlezon, W.A., Jr., Devine, D.P., Wise, R.A., 1995. Habit-forming actions of nomifensine in nucleus accumbens. Psychopharmacology 122, 194-197.
10. Carlezon, W.A., Jr., Wise, R.A., 1996. Rewarding actions of phencyclidine and related drugs in nucleus accumbens shell and frontal cortex. J. Neurosci. 16, 3112-3122.
11. Carr, G.D., White, N.M., 1983. Conditioned place preference from intra-accumbens but not intra-caudate amphetamine injections. Life Sci. 33, 2551-2557.
12. Charara, A., Smith, Y., Parent, A., 1996. Glutamatergic inputs from the pedunculopontine nucleus to midbrain dopaminergic neurons in primates: Phaseolus vulgaris-Leocoagglutinin anterograde labeling combined with postembedding glutamate and GABA immunohistochemistry. J. Comp. Neurol. 364, 254-266.
13. Clarke, P.B.S., 1984. Chronic central nicotinic blockade after a single administration of the bisquaternary ganglion-blocking drug chlorisondamine. Br. J. Pharmacol. 83, 527-535.
14. Clarke, P.B.S., Hommer, D.W., Pert, A., Skirboll, L.R., 1985. Electrophysiological actions of nicotine on substantia nigra single units. Br. J. Pharmacol. 85, 827-835.
15. Clarke, P.B.S., Jakubovic, A., Fibiger, H.C., 1988. Evidence that mesolimbic dopaminergic activation underlies the locomotor stimulant action of nicotine in rats. J. Pharmacol. Exp. Ther. 246, 701-708.
16. Clarke, P.B.S., Pert, A., 1985. Autoradiographic evidence for nicotine receptors on nigrostriatal and mesolimbic dopaminergic neurons. Brain Res. 348, 355-358.
17. Corbett, D., Wise, R.A., 1980. Intracranial self-stimulation in relation to the ascending dopaminergic systems of the midbrain: A moveable electrode mapping study. Brain Res. 185, 1-15.
18. Corrigall, W.A., Coen, K.M., Adamson, K.L., 1994. Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area. Brain Res. 653, 278-284.
19. Corrigall, W.A., Franklin, K.B.J., Coen, K.M., Clarke, P., 1992. The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine. Psychopharmacology 107, 285-289.
20. Corrigall, W.A., Vaccarino, F.J., 1988. Antagonist treatment in nucleus accumbens or periaqueductal grey affects heroin self-administration. Pharmacol. Biochem. Behav. 30, 443-450.
21. Davis, W.M., Smith, S.G., 1977. Catecholaminergic mechanisms of reinforcement: Direct assessment by drug self-administration. Life Sci. 20, 483-492.
22. de Wit, H., Wise, R.A., 1977. Blockade of cocaine reinforcement in rats with the dopamine receptor blocker pimozide but not with the noradrenergic blockers phentolamine or phenoxybenzamine. Can. J. Psychol. 31, 195-203.
23. Devane, W.A., Dysarz, F.A., Johnson, M.R., Melvin, L.S., Howlett, A.C., 1988. Determination and characterization of a cannabinoid receptor in rat brain. Mol. Pharmacol. 34, 605-613.
24. Devane, W.A., Hanus, L., Breuer, A., et al., 1992. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258, 1946-1949.
25. Devine, D.P., Leone, P., Pocock, D., Wise, R.A., 1993. Differential involvement of ventral tegmental mu, delta, and kappa opioid receptors in modulation of basal mesolimbic dopamine release: In vivo microdialysis studies. J. Pharmacol. Exp. Ther. 266, 1236-1246.
26. Devine, D.P., Wise, R.A., 1994. Self-administration of morphine, DAMGO, and DPDPE into the ventral tegmental area of rats. J. Neurosci. 14, 1978-1984.
27. Di Chiara, G., Imperato, A., 1985. Ethanol preferentially stimulates dopamine release in the nucleus accumbens of freely moving rats. Eur. J. Pharmacol. 115, 131-132.
28. Dworkin, S.I., Goeders, N.B., Smith, I.E., 1986. The reinforcing and rate effects of intracranial dopamine administration. In: Harris, L.S. (Eds.), Problems of Drug Dependence, 1985. National Institute on Drug Abuse, Washington.
29. 3H]-chlorisondamine. Br. J. Pharmacol. 116, 2503-2509.
30. Ettenberg, A., Geist, T.D., 1991. Animal model for investigating the anxiogenic effects of self-administered cocaine. Psychopharmacology 103, 455-461.
31. Finlay, J.M., Damsma, G., Fibiger, H.C., 1992. Benzodiazepine-induced decreases in extracellular concentrations of dopamine in the nucleus accumbens after acute and repeated administration. Psychopharmacology 106, 202-208.
32. Fletcher, P.J., 1993. Conditioned place preference induced by microinjection of 8-OH-DPAT into the dorsal or median raphe nucleus. Psychopharmacology 113, 31-36.
33. Fletcher, P.J., Tampakeras, M., Yeomans, J.S., 1995. Median raphe injections of 8-OH-DPAT lower frequency thresholds for lateral hypothalamic self-stimulation. Pharmacol. Biochem. Behav. 52, 65-71.
34. Fouriezos, G., Wise, R.A., 1976. Pimozide-induced extinction of intracranial self-stimulation: response patterns rule out motor or performance deficits. Brain Res. 103, 377-380.
35. Fouriezos, G., Wise, R.A., 1984. Current-distance relation for rewarding brain stimulation. Behav. Brain Res. 14, 85-89.
36. Gallistel, C.R., Freyd, G., 1987. Quantitative determination of the effects of catecholaminergic agonists and antagonists on the rewarding efficacy of brain stimulation. Pharmacol. Biochem. Behav. 26, 731-741.
37. Gallistel, C.R., Shizgal, P., Yeomans, J., 1981. A portrait of the substrate for self-stimulation. Psychol. Rev. 88, 228-273.
38. Gessa, G.L., Muntoni, F., Collu, M., Vargiu, L., Mereu, G., 1985. Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area. Brain Res. 348, 201-204.
39. Goeders, N.B., Smith, J.E., 1983. Cortical dopaminergic involvement in cocaine reinforcement. Science 221, 773-775.
40. Goeders, N.B., Smith, J.E., 1993. Intracranial cocaine self-administration into the medial prefrontal cortex increases dopamine turnover in the nucleus accumbens. J. Pharmacol. Exp. Ther. 265, 592-600.
41. Goldstein, A., Lowney, L.I., Pal, B.K., 1971. Stereospecific and nonspecific interactions of the morphine congener levorphanol in subcellular fractions of mouse brain, 68, 1742-1747.
42. Grace, A.A., Bunney, B.S., 1979. Paradoxical GABA excitation of nigral dopaminergic cells: indirect mediation through reticulata inhibitory neurons. Eur. J. Pharmacol. 59, 211-218.
43. Gracy, K.N., Svingos, A.L., Pickel, V.M., 1997. Dual ultrastructural localization of mu-opioid receptors and NMDA-type glutamate receptors in the shell of the rat nucleus accumbens. J. Neurosci. 17, 4839-4848.
44. Gratton, A., Wise, R.A., 1985. Hypothalamic reward mechanism: Two first-stage fiber populations with a cholinergic component. Science 227, 545-548.
45. 3H]dopamine in rat brain tissue slices. Biochem. Pharmacol. 24, 847-852.
46. 3H-norepinephrine in slices of rat neostriatum and cerebral cortex. J. Pharmacol. Exp. Ther. 194, 47-56.
47. Herkenham, M., Lynn, A.B., de Costa, B.R., Richfield, E.K., 1991. Neuronal localization of cannabinoid receptors in the basal ganglia of the rat. Brain Res. 547, 267-274.
48. Hoebel, E.G., Monaco, A.P., Hernandez, L., Aulisi, E.F., Stanley, B.G., Lenard, L., 1983. Self-injection of amphetamine directly into the brain. Psychopharmacology 81, 158-163.
49. Imperato, A., Mulas, A., Di Chiara, G., 1986. Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats. Eur. J. Pharmacol. 132, 337-338.
50. Jiang, Z.G., North, R.A., 1992. Pre- and postsynaptic inhibition by opioids in rat striatum. J. Neurosci. 12, 356-361.
51. Johnson, S.W., North, R.A., 1992. Opioids excite dopamine neurons by hyperpolarization of local interneurons. J. Neurosci. 12, 483-488.
52. Josefsson, J.-O., Johansson, P., 1979. Naloxone-reversible effect of opioids on pinocytosis in Amoeba proteus. Nature 282, 78-80.
53. Kalivas, P.W., Churchill, L., Klitenick, M.A., 1993. GABA and enkephalin projection from the nucleus accumbens and ventral pallidum to the ventral tegmental area. Neuroscience 57, 1047-1060.
54. Kalivas, P.W., Widerlov, E., Stanley, D., Breese, G., Prange, A.J., 1983. Enkephalin action on the mesolimbic system: A dopamine-dependent and a dopamine-independent increase in locomotor activity. J. Pharmacol. Exp. Ther. 227, 229-237.
55. Kavaliers, M., Hirst, M., 1987. Slugs and snails and opiate tales: opioids and feeding behavior in invertebrates. Fed. Proc. 46, 168-172.
56. Kofman, O., McGlynn, S.M., Olmstead, M.C., Yeomans, J.S., 1990. Differential effects of atropine, procaine and dopamine in the rat ventral tegmentum on lateral hypothalamic rewarding brain stimulation. Behav. Brain Res. 38, 55-68.
57. Lacosta, S., Roberts, D.C.S., 1993. MDL 72222, ketanserin, and methysergide pretreatments fail to alter breaking points on a progressive ratio schedule reinforced by intravenous cocaine. Pharmacol. Biochem. Behav. 44, 161-165.
58. Lavoie, B., Parent, A., 1994. Pedunculopontine nucleus in the squirrel monkey: cholinergic and glutamatergic projections to the substantia nigra. J. Comp. Neurol. 344, 232-241.
59. Liebman, J.M., Butcher, L.L., 1973. Effects on Self-Stimulation Behavior of Drugs Influencing Dopaminergic Neurotransmission, 277, pp. 305-318.
60. Loh, E.A., Roberts, D.C.S., 1990. Break-points on a progressive ratio schedule reinforced by intravenous cocaine increase following depletion of forebrain serotonin. Psychopharmacology 101, 262-266.
61. Lupica, C.R., 1995. Delta and mu enkephalins inhibit spontaneous GABA-mediated IPSCs via a cyclic AMP-independent mechanism in the rat hypothalamus. J. Neurosci. 15, 737-749.
62. Lyness, W.H., Friedle, N.M., Moore, K.E., 1979. Destruction of dopaminergic nerve terminals in nucleus accumbens: effect on D-amphetamine self-administration. Pharmacol. Biochem. Behav. 11, 553-556.
63. Lyness, W.H., Moore, K.E., 1983. Increased self-administration of D-amphetamine by rats pretreated with metergoline. Pharmacol. Biochem. Behav. 18, 721-724.
64. 3H]TCP-labelled receptors in rat brain. J. Neurosci. 8, 493-501.
65. Marks, M.J., Stitzel, J.A., Romm, E., Wehner, J.M., Collins, A.C., 1986. Nicotinic binding sites in rat and mouse brain: comparison of acetylcholine, nicotine, and a-bungarotoxin. Molec. Pharmacol. 30, 427-436.
66. Martin-Iverson, M.T., Szostak, C., Fibiger, H.C., 1986. 6-Hydroxydopamine lesions of the medial prefrontal cortex fail to influence intravenous self-administration of cocaine. Psychopharmacology 88, 310-314.
67. McGregor, I.S., Atrens, D.M., Jackson, D.M., 1992. Cocaine facilitation of prefrontal cortex self-stimulation: a microstructural and pharmacological analysis. Psychopharmacology 106, 239-247.
68. Mihic, S.J., Ye, Q., Wick, M.J., et al., 1997. Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. Nature 389, 385-389.
69. Miliaressis, E., Malette, J., Coulombe, D., 1986. The Effects of Pimozide on the Reinforcing Efficacy of Central Grey Stimulation in the Rat, 21, pp. 95-100.
70. Murray, B., Shizgal, P., 1994. Evidence implicating both slow- and fast-conducting fibers in the rewarding effect of medial forebrain bundle stimulatin. Behav. Brain Res. 63, 47-60.
71. Museo, E., Wise, R.A., 1994. Place preference conditioning with ventral tegmental injections of cytisine. Life Sci. 55, 1179-1186.
72. 9-tetrahydrocannabinol on potassium-evoked release of dopamine in the rat caudate nucleus: An in vivo electrochemical and in vivo dialysis study. Brain Res. 451, 59-68.
73. Nieuwenhuys, R., Geeraedts, M.G., Veening, J.G., 1982. The medial forebrain bundle of the rat. I. General introduction. J. Comp. Neurol. 206, 49-81.
74. Oakman, S.A., Faris, P.L., Kerr, P.E., Cozzari, C., Hartman, B.K., 1995. Distribution of pontomesencephalic cholinergic neurons projecting to substantia nigra differs significantly from those projecting to ventral tegmental area. J. Neurosci. 15, 5859-5869.
75. Olds, J., Milner, P.M., 1954. Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain. J. Comp. Physiol. Psychol. 47, 419-427.
76. Olds, J., Olds, M.E., 1965. Drives, rewards, and the brain. In: Newcombe, T.M. (Eds.), New Directions in Psychology. Holt, Rinehart and Winston, New York, pp. 327-410.
77. Olds, M.E., 1979. Hypothalamic substrate for the positive reinforcing properties of morphine in the rat. Brain Res. 168, 351-360.
78. Olds, M.E., 1982. Reinforcing effects of morphine in the nucleus accumbens. Brain Res. 237, 429-440.
79. Olds, M.E., Olds, J., 1963. Approach-avoidance analysis of rat diencephalon. J. Comp. Neurol. 120, 259-295.
80. Phillips, A.G., 1970. Enhancement and inhibition of olfactory bulb self-stimulation by odours. Physiol. Behav. 5, 1127-1131.
81. Phillips, A.G., 1984. Brain reward circuitry: A case for separate systems. Brain. Res. Bull. 12, 195-201.
82. Phillips, A.G., LePiane, F.G., 1980. Reinforcing effects of morphine microinjection into the ventral tegmental area. Pharmacol. Biochem. Behav. 12, 965-968.
83. Prado-Alcala, R., Wise, R.A., 1984. Brain stimulation reward and dopamine terminal fields. I. Caudate-putamen, nucleus accumbens and amygdala, 297, pp. 2650-273.
84. Roberts, D.C.S., Corcoran, M.E., Fibiger, H.C., 1977. On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine. Pharmacol. Biochem. Behav. 6, 615-620.
85. Roberts, D.C.S., Koob, G.F., Klonoff, P., Fibiger, H.C., 1980. Extinction and recovery of cocaine self-administration following 6-OHDA lesions of the nucleus accumbens. Pharmacol. Biochem. Behav. 12, 781-787.
86. Rompré, P.-P., Miliaressis, E., 1985. Pontine and mesencephalic substrates of self-stimulation, 359, pp. 246-259.
87. Routtenberg, A., Malsbury, C., 1969. Brainstem pathways of reward. J. Comp. Physiol. Psychol. 68, 22-30.
88. Routtenberg, A., Sloan, M., 1972. Self-stimulation in the frontal cortex of Rattus norvegicus. Behav. Biol. 7, 567-572.
89. Saleem, A., Zhu, Y., Druhan, J., Aston-Jones, G., 1996. Innervation of the nucleus accumbens shell and ventral tegmental area by dopamine beta-hydroxylase-positive fibers: possible sites for norepinephrine-dopamine interactions. Soc. Neurosci. Abstr., in press.
90. Schenk, S., Horger, B.A., Peltier, R., Shelton, K., 1991. Supersensitivity to the reinforcing effects of cocaine following 6-hydroxydopamine lesions to the medial prefrontal cortex in rats. Brain Res. 543, 227-235.
91. Sesack, S.R., Pickel, V.M., 1992. Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area. J. Comp. Neurol. 320, 145-160.
92. Shizgal, P., 1989. Toward a cellular analysis of intracranial self-stimulation: contributions of collision studies. Neurosci. Biobehav. Rev. 13, 81-90.
93. Shizgal, P., Bielajew, C., Corbett, D., Skelton, R., Yeomans, J., 1980. Behavioral methods for inferring anatomical linkage between rewarding brain stimulation sites. J. Comp. Physiol. Psychol. 94, 227-237.
94. Snyder, S.H., Katims, J.J., Annau, A., Bruns, R.F., Daly, J.W., 1981. Adenosine receptors and the behavioral actions of methylxanthines. Proc. Natl. Acad. Sci. U.S.A. 78, 3260-3264.
95. Stein, L., 1971. Neurochemistry of reward and punishment: Some implications for the etiology of schizophrenia. J. Psychiatry Res. 8, pp. 345-361.
96. Stevens, K.E., Shiotsu, G., Stein, L., 1991. Hippocampal μ-receptors mediate opioid reinforcement in the CA3 region. Brain Res. 545, 8-16.
97. A receptor-mediated inhibition of rat substantia nigra dopaminergic neurons by pars reticulata projection neurons. J. Neurosci. 15, 3092-3103.
98. Van Bockstaele, E.J., Pickel, V.M., 1995. GABA-containing neurons in the ventral tegmental area project to the nucleus accumbens in rat brain. Brain Res. 682, 215-221.
99. van der Kooy, D., Mucha, R.F., O'Shaughnessy, M., Bucenieks, P., 1982. Reinforcing effects of brain microinjections of morphine revealed by conditioned place preference. Brain Res. 243, 107-117.
100. Van Der Kooy, D., Phillips, A.G., 1977. Trigeminal substrates of intracranial self-stimulation. Science 196, 447-449.
101. Wallace, D.M., Magnuson, D.J., Gray, T.S., 1992. Organization of amygdaloid projections to brainstem dopaminergic, noradrenergic, and adrenergic cell groups in the rat. Brain Res. Bull. 28, 447-454.
102. Westfall, T.C., Grant, H., Perry, H., 1988. Release of dopamine and 5-hydroxytryptamine from rat striatal slices following activation of nicotinic cholinergic receptors. Gen. Pharmacol. 14, 321-325.
103. Wise, R.A., 1978. Catecholamine theories of reward: A critical review. Brain Res. 152, 215-247.
104. Wise, R.A., 1980. Yes, but!...a response to Arbuthnott. Trends Neurosci. 3, 200.
105. Wise, R.A., 1981. Intracranial self-stimulation: Mapping against the lateral boundaries of the dopaminergic cells of the substantia nigra. Brain Res. 213, 190-194.
106. Wise, R.A., 1989. Opiate reward: Sites and substrates. Neurosci. Biobehav. Rev. 13, 129-133.
107. Wise, R.A., Bozarth, M.A., 1984. Brain reward circuitry: Four circuit elements 'wired' in apparent series. Brain Res. Bull. 12, 203-208.
108. Wise, R.A., Marcangione, C., Bauco, P., 1997. Blockade of the reward-potentiating effects of nicotine on lateral hypothalamic brain stimulation reward by chlorisondamine. Synapse, in press.
109. Wise, R.A., Rompré, P.-P., 1989. Brain dopamine and reward. Ann. Rev. Psychol. 40, 191-225.
110. Wood, P.L., 1982. Actions of GABAergic agents on dopamine metabolism in the nigrostriatal pathway of the rat. J. Pharmacol. Exp. Ther. 222, 674-679.
111. Woolf, N.J., Butcher, L.L., 1986. Cholinergic systems in the rat brain: III. Projections from the pontomesencephalic tegmentum to the thalamus, tectum, basal ganglia, and basal forebrain. Brain Res. Bull. 16, 603-637.
112. Yeomans, J.S., 1979. Absolute refractory periods of self-stimulation neurons. Physiol. Behav. 22, 911-919.
113. Yeomans, J.S., Maidment, N.T., Bunney, B.S., 1988. Excitability properties of medial forebrain bundle axons of A9 and A10 dopamine cells. Brain Res. 450, 86-93.
114. Yeomans, J.S., Mathur, A., Tampakeras, M., 1993. Rewarding brain stimulation: Role of tegmental cholinergic neurons that activate dopamine neurons. Behav. Neurosci. 107, 1077-1087.
115. Yokel, R.A., Wise, R.A., 1975. Increased lever-pressing for amphetamine after pimozide in rats: Implications for a dopamine theory of reward. Science 187, 547-549.