Opioid receptor probes derived from cycloaddition of the hallucinogen natural product salvinorin A

Journal of Natural Products

Volumn 74, Issue 4, 2011, Pages 718-726

  Lozama, Anthony ^a   Cunningham, Christopher W ^b   Caspers, Michael J ^b   Douglas, Justin T ^b   Dersch, Christina M ^c   Rothman, Richard B ^c   Prisinzano, Thomas E ^b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF KANSAS   (United States)

^c DHHS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,6 EPOXY 3 METHYL 3,6 DIHYDROTRIBENZOCYCLOHEPTATRIENONE; AROMATIC COMPOUND; BENZENE DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; DIETHYL 4 [ 9 ACETOXY 7 (METHOXYCARBONYL) 6A,10B DIMETHYL 4,10 DIOXODODECAHYDRO 1H BENZO[F]ISOCHROMEN 2 YL]PHTHALATE; DIETHYL 5 [9 ACETOXY 7 (METHOXYCARBONYL) 6A,10B DIMETHYL 4,10 DIOXODODECAHYDRO 1H BENZO[F]ISOCHROMEN 2 YL] 7 OXABICYCLO[2.2.1]HEPTA 2,5 DIENE 2,3 DICARBOXYLATE; DIMETHYL 4 [ 9 ACETOXY 7 (METHOXYCARBONYL) 6A,10B DIMETHYL 4,10 DIOXODODECAHYDRO 1H BENZO[F]ISOCHROMEN 2 YL)PHTHALATE; DIMETHYL 5 [ 9 ACETOXY 7 (METHOXYCARBONYL) 6A,10B DIMETHYL 4,10 DIOXODODECAHYDRO 1H BENZO[F]ISOCHROMEN 2 YL] 7 OXABICYCLO[2.2.1]HEPTA 2,5 DIENE 2,3 DICARBOXYLATE; FURAN DERIVATIVE; KAPPA OPIATE RECEPTOR; METHYL 9 ACETOXY 2 (7 BENZOOXABICYCLO[2.2.1]HEPTA 2,5 DIEN 2 YL) 6A,10B DIMETHYL 4,10 DIOXODODECAHYDRO 1H BENZO[F]ISOCHROMENE 7 CARBOXYLATE; METHYL 9 ACETOXY 2 (8,8A,9,12,12A,13 HEXAHYDRO 8 METHYL 8,13:9,12 DIEPOXY 5H DIBENZO[3,4:6,7]CYCLOHEPT[1,2]NAPHTHANEN 5 ON 10 YL) 6A,10B DIMETHYL 4,10 DIOXODODECAHYDRO 1H BENZO[F]ISOCHROMENE 7 CARBOXYLATE; METHYL 9 ACETOXY 2 (8,8A,9,12,12A,13 HEXAHYDRO 8,13:9,12 DIEPOXY 5H DIBENZO[3,4:6,7]CYCLOHEPT[1,2]NAPHTHANEN 5 ON 10 YL) 6A,10B DIMETHYL 4,10 DIOXODODECAHYDRO 1H BENZO[F]ISOCHROMENE 7 CARBOXYLATE; METHYL 9 ACETOXY 2 [3 (ETHOXYCARBONYL) 4 (TRIFLUOROMETHYL)PHENYL] 6A,10B DIMETHYL 4,10 DIOXODODECAHYDRO 1H BENZO[F]ISOCHROMENE 7 CARBOXYLATE; METHYL 9 ACETOXY 2 [4 (ETHOXYCARBONYL) 3 (TRIFLUOROMETHYL)PHENYL] 6A,10B DIMETHYL 4,10 DIOXODODECAHYDRO 1H BENZO[F]ISOCHROMENE 7 CARBOXYLATE; METHYL 9 ACETOXY 2 [5 (ETHOXYCARBONYL) 6 (TRIFLUOROMETHYL) 7 OXABICYCLO[2.2.1]HEPTA 2,5 DIEN 2 YL] 6A,10B DIMETHYL 4,10 DIOXODODECAHYDRO 1H BENZO[F]ISOCHROMENE 7 CARBOXYLATE; METHYL 9 ACETOXY 2 [6 (ETHOXYCARBONYL) 5 (TRIFLUOROMETHYL) 7 OXABICYCLO[2.2.1]HEPTA 2,5 DIEN 2 YL] 6A,10B DIMETHYL 4,10 DIOXODODECAHYDRO 1H BENZO[F]ISOCHROMENE 7 CARBOXYLATE; METHYL 9 ACETOXY 6A,10B DIMETHYL 2 (NAPHTHALEN 2 YL) 4,10 DIOXODODECAHYDRO 1H BENZO[F]ISOCHROMENE 7 CARBOXYLATE; NATURAL PRODUCT; NORBORNADIENE DERIVATIVE; PSYCHEDELIC AGENT; SALVINORIN A; UNCLASSIFIED DRUG;

AROMATIZATION; ARTICLE; BINDING AFFINITY; CYCLOADDITION; DIELS ALDER REACTION; ELECTRON; MICROWAVE RADIATION; MOLECULAR PROBE; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

DITERPENES, CLERODANE; FURANS; HALLUCINOGENS; MOLECULAR STRUCTURE; RECEPTORS, OPIOID, KAPPA; SALVIA; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

ALNUS;

EID: 79955375379     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np1007872     Document Type: Article

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