메뉴 건너뛰기




Volumn 71, Issue 3, 2011, Pages 498-511

Selective p38α MAPK deletion in serotonergic neurons produces stress resilience in models of depression and addiction

Author keywords

[No Author keywords available]

Indexed keywords

CITALOPRAM; COCAINE; KAPPA OPIATE RECEPTOR AGONIST; MITOGEN ACTIVATED PROTEIN KINASE 14; PAROXETINE; TAMOXIFEN;

EID: 79961197759     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2011.06.011     Document Type: Article
Times cited : (213)

References (79)
  • 2
    • 7444232259 scopus 로고    scopus 로고
    • Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice
    • Ansorge M.S., Zhou M., Lira A., Hen R., Gingrich J.A. Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science 2004, 306:879-881.
    • (2004) Science , vol.306 , pp. 879-881
    • Ansorge, M.S.1    Zhou, M.2    Lira, A.3    Hen, R.4    Gingrich, J.A.5
  • 3
    • 28044473638 scopus 로고    scopus 로고
    • Formation of behavioral pathology in female C57BL/6J mice exposed to prolonged negative psychoemotional conditions
    • Avgustinovich D.F., Kovalenko I.L. Formation of behavioral pathology in female C57BL/6J mice exposed to prolonged negative psychoemotional conditions. Neurosci. Behav. Physiol. 2005, 35:959-967.
    • (2005) Neurosci. Behav. Physiol. , vol.35 , pp. 959-967
    • Avgustinovich, D.F.1    Kovalenko, I.L.2
  • 4
    • 0030839236 scopus 로고    scopus 로고
    • Antidepressant drugs inhibit a glial 5-hydroxytryptamine transporter in rat brain
    • Bal N., Figueras G., Vilaró M.T., Suñol C., Artigas F. Antidepressant drugs inhibit a glial 5-hydroxytryptamine transporter in rat brain. Eur. J. Neurosci. 1997, 9:1728-1738.
    • (1997) Eur. J. Neurosci. , vol.9 , pp. 1728-1738
    • Bal, N.1    Figueras, G.2    Vilaró, M.T.3    Suñol, C.4    Artigas, F.5
  • 5
    • 1342281225 scopus 로고    scopus 로고
    • CRF and CRF receptors: role in stress responsivity and other behaviors
    • Bale T.L., Vale W.W. CRF and CRF receptors: role in stress responsivity and other behaviors. Annu. Rev. Pharmacol. Toxicol. 2004, 44:525-557.
    • (2004) Annu. Rev. Pharmacol. Toxicol. , vol.44 , pp. 525-557
    • Bale, T.L.1    Vale, W.W.2
  • 8
    • 0031978809 scopus 로고    scopus 로고
    • Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine (" Ecstasy" ) in serotonin transporter-deficient mice
    • Bengel D., Murphy D.L., Andrews A.M., Wichems C.H., Feltner C.H., Heils A., Mossner R., Westphal H., Lesch K.P. Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine (" Ecstasy" ) in serotonin transporter-deficient mice. Mol. Pharmacol. 1998, 53:649-655.
    • (1998) Mol. Pharmacol. , vol.53 , pp. 649-655
    • Bengel, D.1    Murphy, D.L.2    Andrews, A.M.3    Wichems, C.H.4    Feltner, C.H.5    Heils, A.6    Mossner, R.7    Westphal, H.8    Lesch, K.P.9
  • 10
    • 78649966665 scopus 로고    scopus 로고
    • Dopamine in motivational control: rewarding, aversive, and alerting
    • Bromberg-Martin E.S., Matsumoto M., Hikosaka O. Dopamine in motivational control: rewarding, aversive, and alerting. Neuron 2010, 68:815-834.
    • (2010) Neuron , vol.68 , pp. 815-834
    • Bromberg-Martin, E.S.1    Matsumoto, M.2    Hikosaka, O.3
  • 11
    • 33745832645 scopus 로고    scopus 로고
    • Kappa opioid receptor activation of p38 MAPK is GRK3 and arrestin dependent in neurons and astrocytes
    • Bruchas M.R., Macey T.A., Lowe J., Chavkin C. Kappa opioid receptor activation of p38 MAPK is GRK3 and arrestin dependent in neurons and astrocytes. J. Biol. Chem. 2006, 281:18081-18089.
    • (2006) J. Biol. Chem. , vol.281 , pp. 18081-18089
    • Bruchas, M.R.1    Macey, T.A.2    Lowe, J.3    Chavkin, C.4
  • 12
    • 35548997505 scopus 로고    scopus 로고
    • Stress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria
    • Bruchas M.R., Land B.B., Aita M., Xu M., Barot S.K., Li S., Chavkin C. Stress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria. J. Neurosci. 2007, 27:11614-11623.
    • (2007) J. Neurosci. , vol.27 , pp. 11614-11623
    • Bruchas, M.R.1    Land, B.B.2    Aita, M.3    Xu, M.4    Barot, S.K.5    Li, S.6    Chavkin, C.7
  • 13
    • 75149183092 scopus 로고    scopus 로고
    • The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors
    • Bruchas M.R., Land B.B., Chavkin C. The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors. Brain Res. 2010, 1314:44-55.
    • (2010) Brain Res. , vol.1314 , pp. 44-55
    • Bruchas, M.R.1    Land, B.B.2    Chavkin, C.3
  • 15
    • 78650068881 scopus 로고    scopus 로고
    • Mesolimbic dopamine neurons in the brain reward circuit mediate susceptibility to social defeat and antidepressant action
    • Cao J.L., Covington H.E., Friedman A.K., Wilkinson M.B., Walsh J.J., Cooper D.C., Nestler E.J., Han M.H. Mesolimbic dopamine neurons in the brain reward circuit mediate susceptibility to social defeat and antidepressant action. J. Neurosci. 2010, 30:16453-16458.
    • (2010) J. Neurosci. , vol.30 , pp. 16453-16458
    • Cao, J.L.1    Covington, H.E.2    Friedman, A.K.3    Wilkinson, M.B.4    Walsh, J.J.5    Cooper, D.C.6    Nestler, E.J.7    Han, M.H.8
  • 18
    • 57749097458 scopus 로고    scopus 로고
    • Unfaithful neurotransmitter transporters: focus on serotonin uptake and implications for antidepressant efficacy
    • Daws L.C. Unfaithful neurotransmitter transporters: focus on serotonin uptake and implications for antidepressant efficacy. Pharmacol. Ther. 2009, 121:89-99.
    • (2009) Pharmacol. Ther. , vol.121 , pp. 89-99
    • Daws, L.C.1
  • 19
    • 0032533330 scopus 로고    scopus 로고
    • Rotating disk electrode voltammetric measurements of dopamine transporter activity: an analytical evaluation
    • Earles C., Schenk J.O. Rotating disk electrode voltammetric measurements of dopamine transporter activity: an analytical evaluation. Anal. Biochem. 1998, 264:191-198.
    • (1998) Anal. Biochem. , vol.264 , pp. 191-198
    • Earles, C.1    Schenk, J.O.2
  • 20
    • 84856223404 scopus 로고    scopus 로고
    • Emotional memory impairments in a genetic rat model of depression: involvement of 5-HT/MEK/Arc signaling in restoration
    • in press. Published online January 18, 2011
    • Eriksson T.M., Delagrange P., Spedding M., Popoli M., Mathé A.A., Ogren S.O., Svenningsson P. Emotional memory impairments in a genetic rat model of depression: involvement of 5-HT/MEK/Arc signaling in restoration. Mol. Psychiatry 2011, in press. Published online January 18, 2011. 10.1038/mp.2010.131.
    • (2011) Mol. Psychiatry
    • Eriksson, T.M.1    Delagrange, P.2    Spedding, M.3    Popoli, M.4    Mathé, A.A.5    Ogren, S.O.6    Svenningsson, P.7
  • 21
    • 0345258497 scopus 로고    scopus 로고
    • The developmental role of serotonin: news from mouse molecular genetics
    • Gaspar P., Cases O., Maroteaux L. The developmental role of serotonin: news from mouse molecular genetics. Nat. Rev. Neurosci. 2003, 4:1002-1012.
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 1002-1012
    • Gaspar, P.1    Cases, O.2    Maroteaux, L.3
  • 22
    • 0035073901 scopus 로고    scopus 로고
    • Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice
    • Gingrich J.A., Hen R. Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice. Psychopharmacology 2001, 155:413-421.
    • (2001) Psychopharmacology , vol.155 , pp. 413-421
    • Gingrich, J.A.1    Hen, R.2
  • 23
    • 57649186957 scopus 로고    scopus 로고
    • A novel protein kinase A-independent, beta-arrestin-1-dependent signaling pathway for p38 mitogen-activated protein kinase activation by beta2-adrenergic receptors
    • Gong K., Li Z., Xu M., Du J., Lv Z., Zhang Y. A novel protein kinase A-independent, beta-arrestin-1-dependent signaling pathway for p38 mitogen-activated protein kinase activation by beta2-adrenergic receptors. J. Biol. Chem. 2008, 283:29028-29036.
    • (2008) J. Biol. Chem. , vol.283 , pp. 29028-29036
    • Gong, K.1    Li, Z.2    Xu, M.3    Du, J.4    Lv, Z.5    Zhang, Y.6
  • 24
    • 79551686302 scopus 로고    scopus 로고
    • Depression and antidepressants: insights from knockout of dopamine, serotonin or noradrenaline re-uptake transporters
    • Haenisch B., Bönisch H. Depression and antidepressants: insights from knockout of dopamine, serotonin or noradrenaline re-uptake transporters. Pharmacol. Ther. 2011, 129:352-368.
    • (2011) Pharmacol. Ther. , vol.129 , pp. 352-368
    • Haenisch, B.1    Bönisch, H.2
  • 25
    • 77957652856 scopus 로고    scopus 로고
    • Rotating disk electrode voltammetric measurements of serotonin transporter kinetics in synaptosomes
    • Hagan C.E., Neumaier J.F., Schenk J.O. Rotating disk electrode voltammetric measurements of serotonin transporter kinetics in synaptosomes. J. Neurosci. Methods 2010, 193:29-38.
    • (2010) J. Neurosci. Methods , vol.193 , pp. 29-38
    • Hagan, C.E.1    Neumaier, J.F.2    Schenk, J.O.3
  • 27
    • 29244461748 scopus 로고    scopus 로고
    • Serotonergic modulation of the limbic system
    • Hensler J.G. Serotonergic modulation of the limbic system. Neurosci. Biobehav. Rev. 2006, 30:203-214.
    • (2006) Neurosci. Biobehav. Rev. , vol.30 , pp. 203-214
    • Hensler, J.G.1
  • 28
    • 33745568300 scopus 로고    scopus 로고
    • Temporal control of gene recombination in astrocytes by transgenic expression of the tamoxifen-inducible DNA recombinase variant CreERT2
    • Hirrlinger P.G., Scheller A., Braun C., Hirrlinger J., Kirchhoff F. Temporal control of gene recombination in astrocytes by transgenic expression of the tamoxifen-inducible DNA recombinase variant CreERT2. Glia 2006, 54:11-20.
    • (2006) Glia , vol.54 , pp. 11-20
    • Hirrlinger, P.G.1    Scheller, A.2    Braun, C.3    Hirrlinger, J.4    Kirchhoff, F.5
  • 29
    • 0032101951 scopus 로고    scopus 로고
    • Serotonin transporters in adult rat brain astrocytes revealed by [3H]5-HT uptake into glial plasmalemmal vesicles
    • Hirst W.D., Price G.W., Rattray M., Wilkin G.P. Serotonin transporters in adult rat brain astrocytes revealed by [3H]5-HT uptake into glial plasmalemmal vesicles. Neurochem. Int. 1998, 33:11-22.
    • (1998) Neurochem. Int. , vol.33 , pp. 11-22
    • Hirst, W.D.1    Price, G.W.2    Rattray, M.3    Wilkin, G.P.4
  • 30
    • 50849113451 scopus 로고    scopus 로고
    • Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease
    • Holmes A. Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease. Neurosci. Biobehav. Rev. 2008, 32:1293-1314.
    • (2008) Neurosci. Biobehav. Rev. , vol.32 , pp. 1293-1314
    • Holmes, A.1
  • 31
    • 58149387075 scopus 로고    scopus 로고
    • Corticotropin-releasing factor increases GABA synaptic activity and induces inward current in 5-hydroxytryptamine dorsal raphe neurons
    • Kirby L.G., Freeman-Daniels E., Lemos J.C., Nunan J.D., Lamy C., Akanwa A., Beck S.G. Corticotropin-releasing factor increases GABA synaptic activity and induces inward current in 5-hydroxytryptamine dorsal raphe neurons. J. Neurosci. 2008, 28:12927-12937.
    • (2008) J. Neurosci. , vol.28 , pp. 12927-12937
    • Kirby, L.G.1    Freeman-Daniels, E.2    Lemos, J.C.3    Nunan, J.D.4    Lamy, C.5    Akanwa, A.6    Beck, S.G.7
  • 32
    • 46149120544 scopus 로고    scopus 로고
    • A role for brain stress systems in addiction
    • Koob G.F. A role for brain stress systems in addiction. Neuron 2008, 59:11-34.
    • (2008) Neuron , vol.59 , pp. 11-34
    • Koob, G.F.1
  • 33
    • 54049133277 scopus 로고    scopus 로고
    • The molecular neurobiology of depression
    • Krishnan V., Nestler E.J. The molecular neurobiology of depression. Nature 2008, 455:894-902.
    • (2008) Nature , vol.455 , pp. 894-902
    • Krishnan, V.1    Nestler, E.J.2
  • 35
    • 38349031157 scopus 로고    scopus 로고
    • The dysphoric component of stress is encoded by activation of the dynorphin-kappa opioid system
    • Land B.B., Bruchas M.R., Lemos J., Melief E., Xu M., Chavkin C. The dysphoric component of stress is encoded by activation of the dynorphin-kappa opioid system. J. Neurosci. 2008, 28:407-414.
    • (2008) J. Neurosci. , vol.28 , pp. 407-414
    • Land, B.B.1    Bruchas, M.R.2    Lemos, J.3    Melief, E.4    Xu, M.5    Chavkin, C.6
  • 37
    • 0011566858 scopus 로고    scopus 로고
    • Constitutive activity and differential localization of p38alpha and p38beta MAPKs in adult mouse brain
    • Lee S.H., Park J., Che Y., Han P.L., Lee J.K. Constitutive activity and differential localization of p38alpha and p38beta MAPKs in adult mouse brain. J. Neurosci. Res. 2000, 60:623-631.
    • (2000) J. Neurosci. Res. , vol.60 , pp. 623-631
    • Lee, S.H.1    Park, J.2    Che, Y.3    Han, P.L.4    Lee, J.K.5
  • 38
    • 79951512185 scopus 로고    scopus 로고
    • Stress-hyperresponsive WKY rats demonstrate depressed dorsal raphe neuronal excitability and dysregulated CRF-mediated responses
    • Lemos J.C., Zhang G., Walsh T., Kirby L.G., Akanwa A., Brooks-Kayal A., Beck S.G. Stress-hyperresponsive WKY rats demonstrate depressed dorsal raphe neuronal excitability and dysregulated CRF-mediated responses. Neuropsychopharmacology 2011, 36:721-734.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 721-734
    • Lemos, J.C.1    Zhang, G.2    Walsh, T.3    Kirby, L.G.4    Akanwa, A.5    Brooks-Kayal, A.6    Beck, S.G.7
  • 39
    • 77957285177 scopus 로고    scopus 로고
    • Pet-1 is required across different stages of life to regulate serotonergic function
    • Liu C., Maejima T., Wyler S.C., Casadesus G., Herlitze S., Deneris E.S. Pet-1 is required across different stages of life to regulate serotonergic function. Nat. Neurosci. 2010, 13:1190-1198.
    • (2010) Nat. Neurosci. , vol.13 , pp. 1190-1198
    • Liu, C.1    Maejima, T.2    Wyler, S.C.3    Casadesus, G.4    Herlitze, S.5    Deneris, E.S.6
  • 40
    • 57649155892 scopus 로고    scopus 로고
    • Serotonergic systems, anxiety, and affective disorder: focus on the dorsomedial part of the dorsal raphe nucleus
    • Lowry C.A., Hale M.W., Evans A.K., Heerkens J., Staub D.R., Gasser P.J., Shekhar A. Serotonergic systems, anxiety, and affective disorder: focus on the dorsomedial part of the dorsal raphe nucleus. Ann. N Y Acad. Sci. 2008, 1148:86-94.
    • (2008) Ann. N Y Acad. Sci. , vol.1148 , pp. 86-94
    • Lowry, C.A.1    Hale, M.W.2    Evans, A.K.3    Heerkens, J.4    Staub, D.R.5    Gasser, P.J.6    Shekhar, A.7
  • 41
    • 78149284728 scopus 로고    scopus 로고
    • Role of serotonin transporter inhibition in the regulation of tryptophan hydroxylase in brainstem raphe nuclei: time course and regional specificity
    • MacGillivray L., Lagrou L.M., Reynolds K.B., Rosebush P.I., Mazurek M.F. Role of serotonin transporter inhibition in the regulation of tryptophan hydroxylase in brainstem raphe nuclei: time course and regional specificity. Neuroscience 2010, 171:407-420.
    • (2010) Neuroscience , vol.171 , pp. 407-420
    • MacGillivray, L.1    Lagrou, L.M.2    Reynolds, K.B.3    Rosebush, P.I.4    Mazurek, M.F.5
  • 42
    • 0026674544 scopus 로고
    • Studies of the mechanism of inhibition of the dopamine uptake carrier by cocaine in vitro using rotating disk electrode voltammetry
    • McElvain J.S., Schenk J.O. Studies of the mechanism of inhibition of the dopamine uptake carrier by cocaine in vitro using rotating disk electrode voltammetry. Ann. N Y Acad. Sci. 1992, 654:480-482.
    • (1992) Ann. N Y Acad. Sci. , vol.654 , pp. 480-482
    • McElvain, J.S.1    Schenk, J.O.2
  • 43
    • 0038383854 scopus 로고    scopus 로고
    • Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses
    • McLaughlin J.P., Marton-Popovici M., Chavkin C. Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses. J. Neurosci. 2003, 23:5674-5683.
    • (2003) J. Neurosci. , vol.23 , pp. 5674-5683
    • McLaughlin, J.P.1    Marton-Popovici, M.2    Chavkin, C.3
  • 44
    • 53749094407 scopus 로고    scopus 로고
    • Social stress, therapeutics and drug abuse: preclinical models of escalated and depressed intake
    • Miczek K.A., Yap J.J., Covington H.E. Social stress, therapeutics and drug abuse: preclinical models of escalated and depressed intake. Pharmacol. Ther. 2008, 120:102-128.
    • (2008) Pharmacol. Ther. , vol.120 , pp. 102-128
    • Miczek, K.A.1    Yap, J.J.2    Covington, H.E.3
  • 45
    • 38649099407 scopus 로고    scopus 로고
    • Targeting the murine serotonin transporter: insights into human neurobiology
    • Murphy D.L., Lesch K.P. Targeting the murine serotonin transporter: insights into human neurobiology. Nat. Rev. Neurosci. 2008, 9:85-96.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 85-96
    • Murphy, D.L.1    Lesch, K.P.2
  • 46
    • 34347340642 scopus 로고    scopus 로고
    • Developmental role of tryptophan hydroxylase in the nervous system
    • Nakamura K., Hasegawa H. Developmental role of tryptophan hydroxylase in the nervous system. Mol. Neurobiol. 2007, 35:45-54.
    • (2007) Mol. Neurobiol. , vol.35 , pp. 45-54
    • Nakamura, K.1    Hasegawa, H.2
  • 47
    • 53649102098 scopus 로고    scopus 로고
    • Serotonin transporter transgenic (SERTcre) mouse line reveals developmental targets of serotonin specific reuptake inhibitors (SSRIs)
    • Narboux-Nême N., Pavone L.M., Avallone L., Zhuang X., Gaspar P. Serotonin transporter transgenic (SERTcre) mouse line reveals developmental targets of serotonin specific reuptake inhibitors (SSRIs). Neuropharmacology 2008, 55:994-1005.
    • (2008) Neuropharmacology , vol.55 , pp. 994-1005
    • Narboux-Nême, N.1    Pavone, L.M.2    Avallone, L.3    Zhuang, X.4    Gaspar, P.5
  • 48
    • 77957273984 scopus 로고    scopus 로고
    • Animal models of neuropsychiatric disorders
    • Nestler E.J., Hyman S.E. Animal models of neuropsychiatric disorders. Nat. Neurosci. 2010, 13:1161-1169.
    • (2010) Nat. Neurosci. , vol.13 , pp. 1161-1169
    • Nestler, E.J.1    Hyman, S.E.2
  • 49
    • 10044261073 scopus 로고    scopus 로고
    • P38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload
    • Nishida K., Yamaguchi O., Hirotani S., Hikoso S., Higuchi Y., Watanabe T., Takeda T., Osuka S., Morita T., Kondoh G., et al. p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload. Mol. Cell. Biol. 2004, 24:10611-10620.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 10611-10620
    • Nishida, K.1    Yamaguchi, O.2    Hirotani, S.3    Hikoso, S.4    Higuchi, Y.5    Watanabe, T.6    Takeda, T.7    Osuka, S.8    Morita, T.9    Kondoh, G.10
  • 51
    • 79958158346 scopus 로고    scopus 로고
    • Repeated social defeat increases reactive emotional coping behavior and alters functional responses in serotonergic neurons in the rat dorsal raphe nucleus
    • Paul E.D., Hale M.W., Lukkes J.L., Valentine M.J., Sarchet D.M., Lowry C.A. Repeated social defeat increases reactive emotional coping behavior and alters functional responses in serotonergic neurons in the rat dorsal raphe nucleus. Physiol. Behav. 2011, 104:272-282.
    • (2011) Physiol. Behav. , vol.104 , pp. 272-282
    • Paul, E.D.1    Hale, M.W.2    Lukkes, J.L.3    Valentine, M.J.4    Sarchet, D.M.5    Lowry, C.A.6
  • 52
    • 0033197998 scopus 로고    scopus 로고
    • Ultrastructural localization of the serotonin transporter in limbic and motor compartments of the nucleus accumbens
    • Pickel V.M., Chan J. Ultrastructural localization of the serotonin transporter in limbic and motor compartments of the nucleus accumbens. J. Neurosci. 1999, 19:7356-7366.
    • (1999) J. Neurosci. , vol.19 , pp. 7356-7366
    • Pickel, V.M.1    Chan, J.2
  • 53
    • 0017618768 scopus 로고
    • Depression: a new animal model sensitive to antidepressant treatments
    • Porsolt R.D., Le Pichon M., Jalfre M. Depression: a new animal model sensitive to antidepressant treatments. Nature 1977, 266:730-732.
    • (1977) Nature , vol.266 , pp. 730-732
    • Porsolt, R.D.1    Le Pichon, M.2    Jalfre, M.3
  • 54
    • 34249678451 scopus 로고    scopus 로고
    • Phosphorylation of threonine residue 276 is required for acute regulation of serotonin transporter by cyclic GMP
    • Ramamoorthy S., Samuvel D.J., Buck E.R., Rudnick G., Jayanthi L.D. Phosphorylation of threonine residue 276 is required for acute regulation of serotonin transporter by cyclic GMP. J. Biol. Chem. 2007, 282:11639-11647.
    • (2007) J. Biol. Chem. , vol.282 , pp. 11639-11647
    • Ramamoorthy, S.1    Samuvel, D.J.2    Buck, E.R.3    Rudnick, G.4    Jayanthi, L.D.5
  • 55
    • 34248597065 scopus 로고    scopus 로고
    • Differential regulation and properties of MAPKs
    • Raman M., Chen W., Cobb M.H. Differential regulation and properties of MAPKs. Oncogene 2007, 26:3100-3112.
    • (2007) Oncogene , vol.26 , pp. 3100-3112
    • Raman, M.1    Chen, W.2    Cobb, M.H.3
  • 56
    • 0141519516 scopus 로고    scopus 로고
    • Molecular mechanism of citalopram and cocaine interactions with neurotransmitter transporters
    • Ravna A.W., Sylte I., Dahl S.G. Molecular mechanism of citalopram and cocaine interactions with neurotransmitter transporters. J. Pharmacol. Exp. Ther. 2003, 307:34-41.
    • (2003) J. Pharmacol. Exp. Ther. , vol.307 , pp. 34-41
    • Ravna, A.W.1    Sylte, I.2    Dahl, S.G.3
  • 58
    • 0037319203 scopus 로고    scopus 로고
    • Circuitry underlying regulation of the serotonergic system by swim stress
    • Roche M., Commons K.G., Peoples A., Valentino R.J. Circuitry underlying regulation of the serotonergic system by swim stress. J. Neurosci. 2003, 23:970-977.
    • (2003) J. Neurosci. , vol.23 , pp. 970-977
    • Roche, M.1    Commons, K.G.2    Peoples, A.3    Valentino, R.J.4
  • 59
    • 79952297786 scopus 로고    scopus 로고
    • Metaplasticity governs compartmentalization of synaptic tagging and capture through brain-derived neurotrophic factor (BDNF) and protein kinase Mzeta (PKMzeta)
    • Sajikumar S., Korte M. Metaplasticity governs compartmentalization of synaptic tagging and capture through brain-derived neurotrophic factor (BDNF) and protein kinase Mzeta (PKMzeta). Proc. Natl. Acad. Sci. USA 2011, 108:2551-2556.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 2551-2556
    • Sajikumar, S.1    Korte, M.2
  • 60
    • 12144279565 scopus 로고    scopus 로고
    • A role for p38 mitogen-activated protein kinase in the regulation of the serotonin transporter: evidence for distinct cellular mechanisms involved in transporter surface expression
    • Samuvel D.J., Jayanthi L.D., Bhat N.R., Ramamoorthy S. A role for p38 mitogen-activated protein kinase in the regulation of the serotonin transporter: evidence for distinct cellular mechanisms involved in transporter surface expression. J. Neurosci. 2005, 25:29-41.
    • (2005) J. Neurosci. , vol.25 , pp. 29-41
    • Samuvel, D.J.1    Jayanthi, L.D.2    Bhat, N.R.3    Ramamoorthy, S.4
  • 61
    • 14944356461 scopus 로고    scopus 로고
    • A differentially autoregulated Pet-1 enhancer region is a critical target of the transcriptional cascade that governs serotonin neuron development
    • Scott M.M., Krueger K.C., Deneris E.S. A differentially autoregulated Pet-1 enhancer region is a critical target of the transcriptional cascade that governs serotonin neuron development. J. Neurosci. 2005, 25:2628-2636.
    • (2005) J. Neurosci. , vol.25 , pp. 2628-2636
    • Scott, M.M.1    Krueger, K.C.2    Deneris, E.S.3
  • 62
    • 27644573209 scopus 로고    scopus 로고
    • The role of neuroadaptations in relapse to drug seeking
    • Shaham Y., Hope B.T. The role of neuroadaptations in relapse to drug seeking. Nat. Neurosci. 2005, 8:1437-1439.
    • (2005) Nat. Neurosci. , vol.8 , pp. 1437-1439
    • Shaham, Y.1    Hope, B.T.2
  • 63
    • 0022822520 scopus 로고
    • Differential effects of mu and kappa opioid systems on motivational processes
    • Shippenberg T.S., Herz A. Differential effects of mu and kappa opioid systems on motivational processes. NIDA Res. Monographs 1986, 75:563-566.
    • (1986) NIDA Res. Monographs , vol.75 , pp. 563-566
    • Shippenberg, T.S.1    Herz, A.2
  • 64
    • 0022286256 scopus 로고
    • Cognitive symptoms in late-life depression and their treatment
    • Siegfried K. Cognitive symptoms in late-life depression and their treatment. J. Affect. Disord. 1985, (Suppl 1):S33-S40.
    • (1985) J. Affect. Disord. , Issue.SUPPL. 1
    • Siegfried, K.1
  • 66
    • 0034114458 scopus 로고    scopus 로고
    • Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function
    • Tallquist M.D., Soriano P. Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function. Genesis 2000, 26:113-115.
    • (2000) Genesis , vol.26 , pp. 113-115
    • Tallquist, M.D.1    Soriano, P.2
  • 67
    • 65249109909 scopus 로고    scopus 로고
    • P38 MAPK and beta-arrestin 2 mediate functional interactions between endogenous micro-opioid and alpha2A-adrenergic receptors in neurons
    • Tan M., Walwyn W.M., Evans C.J., Xie C.W. p38 MAPK and beta-arrestin 2 mediate functional interactions between endogenous micro-opioid and alpha2A-adrenergic receptors in neurons. J. Biol. Chem. 2009, 284:6270-6281.
    • (2009) J. Biol. Chem. , vol.284 , pp. 6270-6281
    • Tan, M.1    Walwyn, W.M.2    Evans, C.J.3    Xie, C.W.4
  • 68
    • 0342313687 scopus 로고    scopus 로고
    • Regulation of serotonin release by GABA and excitatory amino acids
    • Tao R., Auerbach S.B. Regulation of serotonin release by GABA and excitatory amino acids. J. Psychopharmacol. (Oxford) 2000, 14:100-113.
    • (2000) J. Psychopharmacol. (Oxford) , vol.14 , pp. 100-113
    • Tao, R.1    Auerbach, S.B.2
  • 69
    • 43449123329 scopus 로고    scopus 로고
    • Neuroplasticity in the mesolimbic dopamine system and cocaine addiction
    • Thomas M.J., Kalivas P.W., Shaham Y. Neuroplasticity in the mesolimbic dopamine system and cocaine addiction. Br. J. Pharmacol. 2008, 154:327-342.
    • (2008) Br. J. Pharmacol. , vol.154 , pp. 327-342
    • Thomas, M.J.1    Kalivas, P.W.2    Shaham, Y.3
  • 70
    • 78649908701 scopus 로고    scopus 로고
    • Depression: a repair response to stress-induced neuronal microdamage that can grade into a chronic neuroinflammatory condition?
    • Wager-Smith K., Markou A. Depression: a repair response to stress-induced neuronal microdamage that can grade into a chronic neuroinflammatory condition?. Neurosci. Biobehav. Rev. 2011, 35:742-764.
    • (2011) Neurosci. Biobehav. Rev. , vol.35 , pp. 742-764
    • Wager-Smith, K.1    Markou, A.2
  • 72
    • 33847795830 scopus 로고    scopus 로고
    • Sciatic nerve ligation-induced proliferation of spinal cord astrocytes is mediated by kappa opioid activation of p38 mitogen-activated protein kinase
    • Xu M., Bruchas M.R., Ippolito D.L., Gendron L., Chavkin C. Sciatic nerve ligation-induced proliferation of spinal cord astrocytes is mediated by kappa opioid activation of p38 mitogen-activated protein kinase. J. Neurosci. 2007, 27:2570-2581.
    • (2007) J. Neurosci. , vol.27 , pp. 2570-2581
    • Xu, M.1    Bruchas, M.R.2    Ippolito, D.L.3    Gendron, L.4    Chavkin, C.5
  • 73
    • 19644367000 scopus 로고    scopus 로고
    • Activation and signaling of the p38 MAP kinase pathway
    • Zarubin T., Han J. Activation and signaling of the p38 MAP kinase pathway. Cell Res. 2005, 15:11-18.
    • (2005) Cell Res. , vol.15 , pp. 11-18
    • Zarubin, T.1    Han, J.2
  • 74
    • 34249331264 scopus 로고    scopus 로고
    • Novel strategies for inhibition of the p38 MAPK pathway
    • Zhang J., Shen B., Lin A. Novel strategies for inhibition of the p38 MAPK pathway. Trends Pharmacol. Sci. 2007, 28:286-295.
    • (2007) Trends Pharmacol. Sci. , vol.28 , pp. 286-295
    • Zhang, J.1    Shen, B.2    Lin, A.3
  • 75
    • 35448933250 scopus 로고    scopus 로고
    • Central serotonergic neurons are differentially required for opioid analgesia but not for morphine tolerance or morphine reward
    • Zhao Z.Q., Gao Y.J., Sun Y.G., Zhao C.S., Gereau R.W., Chen Z.F. Central serotonergic neurons are differentially required for opioid analgesia but not for morphine tolerance or morphine reward. Proc. Natl. Acad. Sci. USA 2007, 104:14519-14524.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 14519-14524
    • Zhao, Z.Q.1    Gao, Y.J.2    Sun, Y.G.3    Zhao, C.S.4    Gereau, R.W.5    Chen, Z.F.6
  • 76
    • 0035425884 scopus 로고    scopus 로고
    • The p38 mitogen-activated protein kinase is involved in associative learning in rabbits
    • Zhen X., Du W., Romano A.G., Friedman E., Harvey J.A. The p38 mitogen-activated protein kinase is involved in associative learning in rabbits. J. Neurosci. 2001, 21:5513-5519.
    • (2001) J. Neurosci. , vol.21 , pp. 5513-5519
    • Zhen, X.1    Du, W.2    Romano, A.G.3    Friedman, E.4    Harvey, J.A.5
  • 77
    • 18144373742 scopus 로고    scopus 로고
    • P38 MAPK activation elevates serotonin transport activity via a trafficking-independent, protein phosphatase 2A-dependent process
    • Zhu C.B., Carneiro A.M., Dostmann W.R., Hewlett W.A., Blakely R.D. p38 MAPK activation elevates serotonin transport activity via a trafficking-independent, protein phosphatase 2A-dependent process. J. Biol. Chem. 2005, 280:15649-15658.
    • (2005) J. Biol. Chem. , vol.280 , pp. 15649-15658
    • Zhu, C.B.1    Carneiro, A.M.2    Dostmann, W.R.3    Hewlett, W.A.4    Blakely, R.D.5
  • 78
    • 14844290256 scopus 로고    scopus 로고
    • Targeted gene expression in dopamine and serotonin neurons of the mouse brain
    • Zhuang X., Masson J., Gingrich J.A., Rayport S., Hen R. Targeted gene expression in dopamine and serotonin neurons of the mouse brain. J. Neurosci. Methods 2005, 143:27-32.
    • (2005) J. Neurosci. Methods , vol.143 , pp. 27-32
    • Zhuang, X.1    Masson, J.2    Gingrich, J.A.3    Rayport, S.4    Hen, R.5
  • 79
    • 48749127367 scopus 로고    scopus 로고
    • Role of NMDA receptors in dopamine neurons for plasticity and addictive behaviors
    • Zweifel L.S., Argilli E., Bonci A., Palmiter R.D. Role of NMDA receptors in dopamine neurons for plasticity and addictive behaviors. Neuron 2008, 59:486-496.
    • (2008) Neuron , vol.59 , pp. 486-496
    • Zweifel, L.S.1    Argilli, E.2    Bonci, A.3    Palmiter, R.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.