Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and the development of bleomycin-induced lung injury

Journal of Pharmacology and Experimental Therapeutics

Volumn 313, Issue 2, 2005, Pages 529-538

  Genovese, Tiziana ^a   Mazzon, Emanuela ^a   Di Paola, Rosanna ^a   Muià, Carmelo ^d   Threadgill, Michael D ^b   Caputi, Achille P ^a   Thiemermann, Christoph ^c   Cuzzocrea, Salvatore ^a  

^a UNIVERSITY OF MESSINA   (Italy)

^b University of Bath   (United Kingdom)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^d University of Messina ^*

Author keywords

[No Author keywords available]

Indexed keywords

1 [7 (4 FLUOROPHENYL) 1,2,3,4 TETRAHYDRO 8 (4 PYRIDYL)PYRAZOLO[5,1 C][1,2,4]TRIAZIN 2 YL] 2 PHENYLETHANEDIONE; 1,11B DIHYDRO 2H BENZOPYRANO[4,3,2 DE]ISOQUINOLIN 3 ONE; 3 AMINOBENZAMIDE; 3 NITROTYROSINE; 5 AMINOISOQUINOLINONE; BLEOMYCIN; GPI 6150; ISOQUINOLINE DERIVATIVE; LIPOCORTIN 5; MYELOPEROXIDASE; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DNA STRAND BREAKAGE; DRUG INDUCED DISEASE; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; EXPERIMENTAL MODEL; HISTOPATHOLOGY; IMMUNOREACTIVITY; IN VIVO STUDY; LUNG EDEMA; LUNG INFILTRATE; LUNG INJURY; MALE; MORTALITY; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WEIGHT REDUCTION;

ANIMALS; BENZAMIDES; BLEOMYCIN; ENZYME INHIBITORS; ISOQUINOLINES; MALE; MICE; POLY(ADP-RIBOSE) POLYMERASES; RESPIRATORY DISTRESS SYNDROME, ADULT; SIGNAL TRANSDUCTION;

EID: 18044390697     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.080705     Document Type: Article

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