-
1
-
-
84871090162
-
Global obesity: Trends, risk factors and policy implications
-
Malik VS, Willett WC, Hu FB. Global obesity: Trends, risk factors and policy implications. Nat. Rev. Endocrinol. 9(1), 13-27 (2013
-
(2013)
Nat. Rev. Endocrinol
, vol.9
, Issue.1
, pp. 13-27
-
-
Malik, V.S.1
Willett, W.C.2
Hu, F.B.3
-
2
-
-
84877803696
-
Pharmacologic treatment options for obesity: What is old is new again
-
Ryan D, Bray G. Pharmacologic treatment options for obesity: What is old is new again. Curr. Hypertens. Rep. 15(3), 182-189 (2013
-
(2013)
Curr. Hypertens. Rep
, vol.15
, Issue.3
, pp. 182-189
-
-
Ryan, D.1
Bray, G.2
-
3
-
-
37249083878
-
Long term pharmacotherapy for obesity and overweight: Updated meta-analysis
-
Diana R, Raj P, Stephanie KL, Cintia C, David CWL. Long term pharmacotherapy for obesity and overweight: Updated meta-analysis. BMJ 335, 1194 (2007
-
(2007)
BMJ
, vol.335
, pp. 1194
-
-
Diana, R.1
Raj, P.2
Stephanie, K.L.3
Cintia, C.4
David, C.W.L.5
-
4
-
-
84857051743
-
Effective weight management practice: A review of the lifestyle intervention evidence
-
Kirk SFL, Penney TL, McHugh TL, Sharma AM. Effective weight management practice: A review of the lifestyle intervention evidence. Int. J. Obes. 36(2), 178-185 (2012
-
(2012)
Int. J. Obes
, vol.36
, Issue.2
, pp. 178-185
-
-
Kirk, S.F.L.1
Penney, T.L.2
McHugh, T.L.3
Sharma, A.M.4
-
6
-
-
79960773090
-
Preservation of beta-cell function: The key to diabetes prevention
-
DeFronzo RA, Abdul-Ghani MA. Preservation of beta-cell function: The key to diabetes prevention. J. Clin. Endocrinol. Metab. 96(8), 2354-2366 (2011
-
(2011)
J. Clin. Endocrinol. Metab
, vol.96
, Issue.8
, pp. 2354-2366
-
-
DeFronzo, R.A.1
Abdul-Ghani, M.A.2
-
7
-
-
77449140027
-
Overview of newer agents: Where treatment is going
-
DeFronzo RA. Overview of newer agents: Where treatment is going. Am. J. Med. 123(3 Suppl.), S38-S48 (2010
-
(2010)
Am. J. Med
, vol.123
, Issue.3 SUPPL.
-
-
DeFronzo, R.A.1
-
8
-
-
84881543697
-
Novel therapies for management of type 2 diabetes mellitus part 2 - Addressing the incretin defect in clinical setting in 2013
-
Grunberger G. Novel therapies for management of type 2 diabetes mellitus part 2 - Addressing the incretin defect in clinical setting in 2013. J. Diabetes 5(3), 241-253 (2013
-
(2013)
J. Diabetes
, vol.5
, Issue.3
, pp. 241-253
-
-
Grunberger, G.1
-
9
-
-
84870225450
-
A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin
-
Egerod KL, Engelstoft MS, Grunddal KV et al. A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin. Endocrinology 153(12), 5782-5795 (2012
-
(2012)
Endocrinology
, vol.153
, Issue.12
, pp. 5782-5795
-
-
Egerod, K.L.1
Engelstoft, M.S.2
Grunddal, K.V.3
-
10
-
-
84877763148
-
Co-localisation and secretion of glucagon-like peptide 1 and peptide YY from primary cultured human L cells
-
Habib AM, Richards P, Rogers GJ, Reimann F, Gribble FM. Co-localisation and secretion of glucagon-like peptide 1 and peptide YY from primary cultured human L cells. Diabetologia 56(6), 1413-1416 (2013
-
(2013)
Diabetologia
, vol.56
, Issue.6
, pp. 1413-1416
-
-
Habib, A.M.1
Richards, P.2
Rogers, G.J.3
Reimann, F.4
Gribble, F.M.5
-
11
-
-
84862743498
-
Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry
-
Habib AM, Richards P, Cairns LS et al. Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry. Endocrinology 153(7), 3054-3065 (2012
-
(2012)
Endocrinology
, vol.153
, Issue.7
, pp. 3054-3065
-
-
Habib, A.M.1
Richards, P.2
Cairns, L.S.3
-
12
-
-
0037784011
-
GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine
-
Mortensen K, Christensen LL, Holst JJ, Orskov C. GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine. Regul. Pep. 114(2G), 189-196 (2003
-
(2003)
Regul. Pep
, vol.114
, Issue.2 G
, pp. 189-196
-
-
Mortensen, K.1
Christensen, L.L.2
Holst, J.J.3
Orskov, C.4
-
13
-
-
84883754628
-
Incretin hormones and the satiation signal
-
Holst JJ. Incretin hormones and the satiation signal. Int. J. Obes. 37(9), 1161-1168 (2013
-
(2013)
Int. J. Obes
, vol.37
, Issue.9
, pp. 1161-1168
-
-
Holst, J.J.1
-
14
-
-
35748957503
-
The physiology of glucagon-like peptide 1
-
Holst JJ. The physiology of glucagon-like peptide 1. Physiol. Rev. 87(4), 1409-1439 (2007
-
(2007)
Physiol. Rev
, vol.87
, Issue.4
, pp. 1409-1439
-
-
Holst, J.J.1
-
15
-
-
0023910424
-
Oxyntomodulin (glicentin-(33-69)): Pharmacokinetics, binding to liver cell membranes, effects on isolated perfused pig pancreas, and secretion from isolated perfused lower small intestine of pigs
-
Baldissera FG, Holst JJ, Knuhtsen S, Hilsted L, Nielsen OV. Oxyntomodulin (glicentin-(33-69)): Pharmacokinetics, binding to liver cell membranes, effects on isolated perfused pig pancreas, and secretion from isolated perfused lower small intestine of pigs. Regul. Pept. 21(1-2), 151-166 (1988
-
(1988)
Regul. Pept
, vol.21
, Issue.1-2
, pp. 151-166
-
-
Baldissera, F.G.1
Holst, J.J.2
Knuhtsen, S.3
Hilsted, L.4
Nielsen, O.V.5
-
16
-
-
84871895669
-
Glucose metabolism is altered after loss of L cells and alfa cells but not influenced by loss of K cells
-
Pedersen J, Ugleholdt RK, Jorgensen SM et al. Glucose metabolism is altered after loss of L cells and alfa cells but not influenced by loss of K cells. Am. J. Physio. Endocrinol. Metab. 304(1), e60-e73 (2013
-
(2013)
Am. J. Physio. Endocrinol. Metab
, vol.304
, Issue.1
-
-
Pedersen, J.1
Ugleholdt, R.K.2
Jorgensen, S.M.3
-
19
-
-
84878854783
-
The role of leptin in the control of insulin-glucose axis
-
Amitani M, Asakawa A, Amitani H, Inui A. The role of leptin in the control of insulin-glucose axis. Front. Neurosci. 7, 51 (2013
-
(2013)
Front. Neurosci
, vol.7
, Issue.51
-
-
Amitani, M.1
Asakawa, A.2
Amitani, H.3
Inui, A.4
-
20
-
-
77953630340
-
The role of gut hormones and the hypothalamus in appetite regulation
-
Suzuki K, Simpson KA, Minnion JS, Shillito JC, Bloom SR. The role of gut hormones and the hypothalamus in appetite regulation. Endocr. J. 57(5), 359-372 (2010
-
(2010)
Endocr. J.
, vol.57
, Issue.5
, pp. 359-372
-
-
Suzuki, K.1
Simpson, K.A.2
Minnion, J.S.3
Shillito, J.C.4
Bloom, S.R.5
-
21
-
-
84872120798
-
The defence of body weight: A physiological basis for weight regain after weight loss
-
Sumithran P, Proietto J. The defence of body weight: A physiological basis for weight regain after weight loss. Clin. Sci. (Lond.) 124(4), 231-241 (2013
-
(2013)
Clin. Sci. (Lond
, vol.124
, Issue.4
, pp. 231-241
-
-
Sumithran, P.1
Proietto, J.2
-
22
-
-
43549116125
-
Gastrointestinal satiety signals
-
Chaudhri OB, Salem V, Murphy KG, Bloom SR. Gastrointestinal satiety signals. Ann. Rev. Physiol. 70, 239-255 (2008
-
(2008)
Ann. Rev. Physiol
, vol.70
, pp. 239-255
-
-
Chaudhri, O.B.1
Salem, V.2
Murphy, K.G.3
Bloom, S.R.4
-
23
-
-
77952243631
-
Brain-derived neurotrophic factor (BDNF) in the hypothalamic ventromedial nucleus increases energy expenditure
-
Wang C, Bomberg E, Billington CJ, Levine AS, Kotz CM. Brain-derived neurotrophic factor (BDNF) in the hypothalamic ventromedial nucleus increases energy expenditure. Brain Res. 1336, 66-77 (2010
-
(2010)
Brain Res
, vol.1336
, pp. 66-77
-
-
Wang, C.1
Bomberg, E.2
Billington, C.J.3
Levine, A.S.4
Kotz, C.M.5
-
24
-
-
69049095170
-
Transcription factors in the development of medial hypothalamic structures
-
Jo YH, Chua S Jr. Transcription factors in the development of medial hypothalamic structures. Am. J. Physiol. Endocrinol. Metab. 297(3), e563-e567 (2009
-
(2009)
Am. J. Physiol. Endocrinol. Metab
, vol.297
, Issue.3
-
-
Jo, Y.H.1
Chua Jr., S.2
-
25
-
-
33845875966
-
Gut hormones and the regulation of energy homeostasis
-
Murphy KG, Bloom SR. Gut hormones and the regulation of energy homeostasis. Nature 444(7121), 854-859 (2006
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 854-859
-
-
Murphy, K.G.1
Bloom, S.R.2
-
26
-
-
84856102513
-
GLP-1 neurons in the nucleus of the solitary tract project directly to the ventral tegmental area and nucleus accumbens to control for food intake
-
Alhadeff AL, Rupprecht LE, Hayes MR. GLP-1 Neurons in the nucleus of the solitary tract project directly to the ventral tegmental area and nucleus accumbens to control for food intake. Endocrinology 153(2), 647-658 (2012
-
(2012)
Endocrinology
, vol.153
, Issue.2
, pp. 647-658
-
-
Alhadeff, A.L.1
Rupprecht, L.E.2
Hayes, M.R.3
-
27
-
-
0033303516
-
Glucagon-like peptide-1-7-36)amide is transformed to glucagon-like peptide-1-9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine
-
Hansen L, Deacon CF, Orskov C, Holst JJ. Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9- 36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine. Endocrinology 140(11), 5356-5363 (1999
-
(1999)
Endocrinology
, vol.140
, Issue.11
, pp. 5356-5363
-
-
Hansen, L.1
Deacon, C.F.2
Orskov, C.3
Holst, J.J.4
-
28
-
-
79960900778
-
Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs
-
Hjollund KR, Deacon CF, Holst JJ. Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs. Diabetologia 54(8), 2206-2208 (2011
-
(2011)
Diabetologia
, vol.54
, Issue.8
, pp. 2206-2208
-
-
Hjollund, K.R.1
Deacon, C.F.2
Holst, J.J.3
-
29
-
-
67649636449
-
Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms
-
Ruttimann EB, Arnold M, Hillebrand JJ, Geary N, Langhans W. Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms. Endocrinology 150(3), 1174-1181 (2009
-
(2009)
Endocrinology
, vol.150
, Issue.3
, pp. 1174-1181
-
-
Ruttimann, E.B.1
Arnold, M.2
Hillebrand, J.J.3
Geary, N.4
Langhans, W.5
-
30
-
-
18144381593
-
The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway
-
Abbott CR, Monteiro M, Small CJ et al. The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway. Brain Res. 1044(1), 127-131 (2005
-
(2005)
Brain Res
, vol.1044
, Issue.1
, pp. 127-131
-
-
Abbott, C.R.1
Monteiro, M.2
Small, C.J.3
-
31
-
-
67449169287
-
Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat
-
978-e78
-
Bucinskaite V, Tolessa T, Pedersen J et al. Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat. Neurogastroenterol. Motil. 21(9), 978-e78 (2009
-
(2009)
Neurogastroenterol. Motil
, vol.21
, Issue.9
-
-
Bucinskaite, V.1
Tolessa, T.2
Pedersen, J.3
-
32
-
-
0030985882
-
Vagal afferent and efferent contributions to the inhibition of food intake by cholecystokinin
-
Moran TH, Baldessarini AR, Salorio CF, Lowery T, Schwartz GJ. Vagal afferent and efferent contributions to the inhibition of food intake by cholecystokinin. Am. J. Physiol. 272(4), R1245-R1251 (1997
-
(1997)
Am. J. Physiol
, vol.272
, Issue.4
-
-
Moran, T.H.1
Baldessarini, A.R.2
Salorio, C.F.3
Lowery, T.4
Schwartz, G.J.5
-
33
-
-
20244369116
-
The role of the vagal nerve in peripheral PYY3-36 induced feeding reduction in rats
-
Koda S, Date Y, Murakami N et al. The role of the vagal nerve in peripheral PYY3-36 induced feeding reduction in rats. Endocrinology 146(5), 2369-2375 (2005
-
(2005)
Endocrinology
, vol.146
, Issue.5
, pp. 2369-2375
-
-
Koda, S.1
Date, Y.2
Murakami, N.3
-
34
-
-
84879189059
-
The effect of exogenous GLP-1 on food intake is lost in male truncally vagotomized subjects with pyloroplasty
-
Plamboeck A, Veedfald S, Deacon CF et al. The effect of exogenous GLP-1 on food intake is lost in male truncally vagotomized subjects with pyloroplasty. Am. J. Physiol. Gastrointest. Liver Physiol. 304(12), G1117-G1127 (2013
-
(2013)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.304
, Issue.12
-
-
Plamboeck, A.1
Veedfald, S.2
Deacon, C.F.3
-
35
-
-
0842325280
-
Receptor gene expression of glucagon-like peptide-1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cells
-
Nakagawa A, Satake H, Nakabayashi H et al. Receptor gene expression of glucagon-like peptide-1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cells. Auton. Neurosci. 110(1), 36-43 (2004
-
(2004)
Auton. Neurosci
, vol.110
, Issue.1
, pp. 36-43
-
-
Nakagawa, A.1
Satake, H.2
Nakabayashi, H.3
-
36
-
-
34748898831
-
Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats
-
Vahl TP, Tauchi M, Durler TS et al. Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats. Endocrinology 148(10), 4965-4973 (2007
-
(2007)
Endocrinology
, vol.148
, Issue.10
, pp. 4965-4973
-
-
Vahl, T.P.1
Tauchi, M.2
Durler, T.S.3
-
37
-
-
84864760434
-
Tight junction in blood-brain barrier: An overview of structure, regulation, and regulator substances
-
Liu WY, Wang ZB, Zhang LC, Wei X, Li L. Tight junction in blood-brain barrier: An overview of structure, regulation, and regulator substances. CNS Neurosci. Ther. 18(8), 609-615 (2012
-
(2012)
CNS Neurosci. Ther
, vol.18
, Issue.8
, pp. 609-615
-
-
Liu, W.Y.1
Wang, Z.B.2
Zhang, L.C.3
Wei, X.4
Li, L.5
-
38
-
-
34347358488
-
The sensory circumventricular organs: Brain targets for circulating signals controlling ingestive behavior
-
Fry M, Ferguson AV. The sensory circumventricular organs: Brain targets for circulating signals controlling ingestive behavior. Physiol. Behav. 91(4), 413-423 (2007
-
(2007)
Physiol. Behav
, vol.91
, Issue.4
, pp. 413-423
-
-
Fry, M.1
Ferguson, A.V.2
-
39
-
-
0029903111
-
Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I
-
Orskov C, Poulsen SS, Moller M, Holst JJ Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I. Diabetes 45(6), 832-835 (1996
-
(1996)
Diabetes
, vol.45
, Issue.6
, pp. 832-835
-
-
Orskov, C.1
Poulsen, S.S.2
Moller, M.3
Holst, J.J.4
-
40
-
-
0036198285
-
Interactions of glucagon-like peptide-1 (GLP-1) with the blood-brain barrier
-
Kastin A, Akerstrom V, Pan W. Interactions of glucagon-like peptide-1 (GLP-1) with the blood-brain barrier. J. Mol. Neurosci. 18(1-2), 7-14 (2002
-
(2002)
J. Mol. Neurosci
, vol.18
, Issue.1-2
, pp. 7-14
-
-
Kastin, A.1
Akerstrom, V.2
Pan, W.3
-
41
-
-
63849248275
-
Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety
-
Williams DL, Baskin DG, Schwartz MW. Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety. Endocrinology 150(4), 1680-1687 (2009
-
(2009)
Endocrinology
, vol.150
, Issue.4
, pp. 1680-1687
-
-
Williams, D.L.1
Baskin, D.G.2
Schwartz, M.W.3
-
42
-
-
0032005005
-
Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
-
Flint A, Raben A, Astrup A, Holst JJ. Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. J. Clin. Invest. 101(3), 515-520 (1998
-
(1998)
J. Clin. Invest
, vol.101
, Issue.3
, pp. 515-520
-
-
Flint, A.1
Raben, A.2
Astrup, A.3
Holst, J.J.4
-
43
-
-
27744584314
-
Effect of peptide YY 3-36 on food intake in humans
-
Degen L, Oesch S, Casanova M et al. Effect of peptide YY 3-36 on food intake in humans. Gastroenterology 129(5), 1430-1436 (2005
-
(2005)
Gastroenterology
, vol.129
, Issue.5
, pp. 1430-1436
-
-
Degen, L.1
Oesch, S.2
Casanova, M.3
-
44
-
-
0028836552
-
Satiety effects of a physiological dose of cholecystokinin in humans
-
Lieverse RJ, Jansen JB, Masclee AA, Lamers CB. Satiety effects of a physiological dose of cholecystokinin in humans. Gut 36(2), 176-179 (1995
-
(1995)
Gut
, vol.36
, Issue.2
, pp. 176-179
-
-
Lieverse, R.J.1
Jansen, J.B.2
Masclee, A.A.3
Lamers, C.B.4
-
45
-
-
77949837737
-
Lesions of area postrema and subfornical organ alter exendin-4-induced brain activation without preventing the hypophagic effect of the GLP-1 receptor agonist
-
Baraboi ED, Smith P, Ferguson AV, Richard D. Lesions of area postrema and subfornical organ alter exendin-4-induced brain activation without preventing the hypophagic effect of the GLP-1 receptor agonist. Am. J. Physiol. Regul. Integr. Comp. Physiol. 298(4), R1098-R1110 (2010
-
(2010)
Am. J. Physiol. Regul. Integr. Comp. Physiol
, vol.298
, Issue.4
-
-
Baraboi, E.D.1
Smith, P.2
Ferguson, A.V.3
Richard, D.4
-
46
-
-
35649021752
-
Gut hormones as mediators of appetite and weight loss after roux-en-Y gastric bypass
-
le Roux CW, Welbourn R, Werling M et al. Gut hormones as mediators of appetite and weight loss after roux-en-Y gastric bypass. Ann. Surg. 246(5), 780-785 (2007
-
(2007)
Ann. Surg
, vol.246
, Issue.5
, pp. 780-785
-
-
Le Roux, C.W.1
Welbourn, R.2
Werling, M.3
-
47
-
-
84887830930
-
Gut hormones, early dumping and resting energy expenditure in patients with good and poor weight loss response after Roux-en-Y gastric bypass
-
doi:10.1038/ijo.2013.15 Epub ahead of print
-
Dirksen C, Jorgensen NB, Bojsen-Moller KN et al. Gut hormones, early dumping and resting energy expenditure in patients with good and poor weight loss response after Roux-en-Y gastric bypass. Int. J. Obes. (Lond.) doi:10.1038/ijo.2013.15 (2013) (Epub ahead of print
-
(2013)
Int. J. Obes. (Lond
-
-
Dirksen, C.1
Jorgensen, N.B.2
Bojsen-Moller, K.N.3
-
48
-
-
83255193972
-
Unsulfated cholecystokinin: An overlooked hormone?
-
Rehfeld JF, Agersnap M. Unsulfated cholecystokinin: An overlooked hormone? Regul. Pept. 173(1-3), 1-5 (2012
-
(2012)
Regul. Pept
, vol.173
, Issue.1-3
, pp. 1-5
-
-
Rehfeld, J.F.1
Agersnap, M.2
-
49
-
-
0026672627
-
Brain and gastrointestinal cholecystokinin receptor family: Structure and functional expression
-
Wank SA, Pisegna JR, de WA. Brain and gastrointestinal cholecystokinin receptor family: Structure and functional expression. Proc. Natl Acad. Sci. USA 89(18), 8691-8695 (1992
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, Issue.18
, pp. 8691-8695
-
-
Wank, S.A.1
Pisegna, J.R.2
De, W.A.3
-
50
-
-
0031782440
-
Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity
-
Deacon CF, Knudsen LB, Madsen K, Wiberg FC, Jacobsen O, Holst JJ. Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity. Diabetologia 41(3), 271-278 (1998
-
(1998)
Diabetologia
, vol.41
, Issue.3
, pp. 271-278
-
-
Deacon, C.F.1
Knudsen, L.B.2
Madsen, K.3
Wiberg, F.C.4
Jacobsen, O.5
Holst, J.J.6
-
51
-
-
0028953577
-
Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo
-
Deacon CF, Johnsen AH, Holst JJ. Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo. J. Clin. Endocrinol. Metab. 80(3), 952-957 (1995
-
(1995)
J. Clin. Endocrinol. Metab
, vol.80
, Issue.3
, pp. 952-957
-
-
Deacon, C.F.1
Johnsen, A.H.2
Holst, J.J.3
-
52
-
-
0022461548
-
Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses
-
Nauck MA, Homberger E, Siegel EG et al. Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses. J. Clin. Endocrinol. Metab. 63(2), 492-498 (1986
-
(1986)
J. Clin. Endocrinol. Metab
, vol.63
, Issue.2
, pp. 492-498
-
-
Nauck, M.A.1
Homberger, E.2
Siegel, E.G.3
-
53
-
-
79959781838
-
Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes
-
Holst JJ, Knop FK, Vilsboll T, Krarup T, Madsbad S. Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes. Diabetes Care 34(Suppl. 2), S251-S257 (2011
-
(2011)
Diabetes Care 34(Suppl. 2
, vol.S251-S257
-
-
Holst, J.J.1
Knop, F.K.2
Vilsboll, T.3
Krarup, T.4
Madsbad, S.5
-
54
-
-
55649108863
-
Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas
-
Heer J, Rasmussen C, Coy DH, Holst JJ. Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas. Diabetologia 51(12), 2263-2270 (2008
-
(2008)
Diabetologia
, vol.51
, Issue.12
, pp. 2263-2270
-
-
Heer, J.1
Rasmussen, C.2
Coy, D.H.3
Holst, J.J.4
-
55
-
-
77954250537
-
The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action
-
Hare KJ, Vilsboll T, Asmar M, Deacon CF, Knop FK, Holst JJ. The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action. Diabetes 59(7), 1765-1770 (2010
-
(2010)
Diabetes
, vol.59
, Issue.7
, pp. 1765-1770
-
-
Hare, K.J.1
Vilsboll, T.2
Asmar, M.3
Deacon, C.F.4
Knop, F.K.5
Holst, J.J.6
-
56
-
-
34248223285
-
Biology of incretins: GLP-1 and GIP
-
Baggio LL, Drucker DJ. Biology of Incretins: GLP-1 and GIP. Gastroenterology 132(6), 2131-2157 (2007
-
(2007)
Gastroenterology
, vol.132
, Issue.6
, pp. 2131-2157
-
-
Baggio, L.L.1
Drucker, D.J.2
-
57
-
-
70350619609
-
Effects of liraglutide in the treatment of obesity: A randomised, double-blind, placebo-controlled study
-
Astrup A, Rössner S, Van Gaal L et al. Effects of liraglutide in the treatment of obesity: A randomised, double-blind, placebo-controlled study. Lancet 374(9701), 1606-1616 (2007
-
(2007)
Lancet
, vol.374
, Issue.9701
, pp. 1606-1616
-
-
Astrup, A.1
Rössner, S.2
Van Gaal, L.3
-
58
-
-
84862207266
-
Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide
-
Astrup A, Carraro R, Finer N et al. Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide. Int. J. Obes. 36(6), 843-854 (2012
-
(2012)
Int. J. Obes
, vol.36
, Issue.6
, pp. 843-854
-
-
Astrup, A.1
Carraro, R.2
Finer, N.3
-
59
-
-
77956301808
-
Preproglucagon derived peptides GLP-1 GLP-2 and oxyntomodulin in the CNS: Role of peripherally secreted and centrally produced peptides
-
Vrang N, Larsen PJ. Preproglucagon derived peptides GLP-1, GLP-2 and oxyntomodulin in the CNS: Role of peripherally secreted and centrally produced peptides. Prog. Neurobiol. 92(3), 442-462 (2010
-
(2010)
Prog. Neurobiol
, vol.92
, Issue.3
, pp. 442-462
-
-
Vrang, N.1
Larsen, P.J.2
-
60
-
-
78650753885
-
Incretin-based therapies for type 2 diabetes mellitus: Properties, functions, and clinical implications
-
Nauck MA. Incretin-based therapies for type 2 diabetes mellitus: Properties, functions, and clinical implications. Am. J. Med. 124(1 Suppl.), S3-S18 (2011
-
(2011)
Am. J. Med
, vol.124
, Issue.1 SUPPL.
-
-
Nauck, M.A.1
-
61
-
-
74349122900
-
Advances in therapy for type 2 diabetes: GLP-1 receptor agonists and DPP-4 inhibitors
-
Davidson JA. Advances in therapy for type 2 diabetes: GLP-1 receptor agonists and DPP-4 inhibitors. Cleve. Clin. J. Med. 76(Suppl. 5), S28-S38 (2009
-
(2009)
Cleve. Clin. J. Med
, vol.76
, Issue.SUPPL. 5
-
-
Davidson, J.A.1
-
62
-
-
79959773411
-
DPP-4 inhibitors: Impact on glycemic control and cardiovascular risk factors
-
Dicker D. DPP-4 inhibitors: Impact on glycemic control and cardiovascular risk factors. Diabetes Care 34(Suppl. 2), S276-S278 (2011
-
(2011)
Diabetes Care 34(Suppl. 2
, vol.S276-S278
-
-
Dicker, D.1
-
63
-
-
77950221874
-
Glucagon and glucagon-like peptides 1 and 2
-
Holst JJ. Glucagon and glucagon-like peptides 1 and 2. Results Probl. Cell Differ. 50, 121-135 (2010
-
(2010)
Results Probl. Cell Differ
, vol.50
, pp. 121-135
-
-
Holst, J.J.1
-
64
-
-
84863448504
-
Exogenous glucagon-like peptide-2 (GLP-2) prevents chemotherapy-induced mucositis in rat small intestine
-
Kissow H, Viby NE, Hartmann B et al. Exogenous glucagon-like peptide-2 (GLP-2) prevents chemotherapy-induced mucositis in rat small intestine. Cancer Chemother. Pharmacol. 70(1), 39-48 (2012
-
(2012)
Cancer Chemother. Pharmacol
, vol.70
, Issue.1
, pp. 39-48
-
-
Kissow, H.1
Viby, N.E.2
Hartmann, B.3
-
65
-
-
84872466358
-
Effect of glucagon-like peptide-2 exposure on bone resorption: Effectiveness of high concentration versus prolonged exposure
-
Askov-Hansen C, Jeppesen PB, Lund P, Hartmann B, Holst JJ, Henriksen DB. Effect of glucagon-like peptide-2 exposure on bone resorption: Effectiveness of high concentration versus prolonged exposure. Regul. Pept. 181, 4-8 (2013
-
(2013)
Regul. Pept
, vol.181
, pp. 4-8
-
-
Askov-Hansen, C.1
Jeppesen, P.B.2
Lund, P.3
Hartmann, B.4
Holst, J.J.5
Henriksen, D.B.6
-
66
-
-
0033914183
-
The proglucagon-derived peptide, glucagon-like peptide-2, is a neurotransmitter involved in the regulation of food intake
-
Tang-Christensen M, Larsen PJ, Thulesen J, Romer J, Vrang N. The proglucagon-derived peptide, glucagon-like peptide-2, is a neurotransmitter involved in the regulation of food intake. Nat. Med. 6(7), 802-807 (2000
-
(2000)
Nat. Med
, vol.6
, Issue.7
, pp. 802-807
-
-
Tang-Christensen, M.1
Larsen, P.J.2
Thulesen, J.3
Romer, J.4
Vrang, N.5
-
67
-
-
0242499995
-
No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects
-
Sorensen LB, Flint A, Raben A, Hartmann B, Holst JJ, Astrup A. No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects. Int. J. Obes. Relat. Metab. Disord. 27(4), 450-456 (2003
-
(2003)
Int. J. Obes. Relat. Metab. Disord
, vol.27
, Issue.4
, pp. 450-456
-
-
Sorensen, L.B.1
Flint, A.2
Raben, A.3
Hartmann, B.4
Holst, J.J.5
Astrup, A.6
-
68
-
-
0242266558
-
Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety
-
Schmidt PT, Näslund E, Grybäck P et al. Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety. Regul. Pep. 116(1-3), 21-25 (2003
-
(2003)
Regul. Pep
, vol.116
, Issue.1-3
, pp. 21-25
-
-
Schmidt, P.T.1
Näslund, E.2
Grybäck, P.3
-
69
-
-
0022398837
-
Human distribution and release of a putative new gut hormone, peptide YY
-
Adrian TE, Ferri GL, Bacarese-Hamilton AJ, Fuessl HS, Polak JM, Bloom SR Human distribution and release of a putative new gut hormone, peptide YY. Gastroenterology 89(5), 1070-1077 (1985
-
(1985)
Gastroenterology
, vol.89
, Issue.5
, pp. 1070-1077
-
-
Adrian, T.E.1
Ferri, G.L.2
Bacarese-Hamilton, A.J.3
Fuessl, H.S.4
Polak, J.M.5
Bloom, S.R.6
-
70
-
-
84856353661
-
CCK PYY and PP: The control of energy balance
-
Simpson K, Parker J, Plumer J, Bloom S. CCK, PYY and PP: The control of energy balance. Handb. Exp. Pharmacol. (209), 209-230 (2012
-
(2012)
Handb. Exp. Pharmacol
, vol.209
, pp. 209-230
-
-
Simpson, K.1
Parker, J.2
Plumer, J.3
Bloom, S.4
-
71
-
-
0024911170
-
Cellular localization half-life and secretion of peptide yy
-
Lluis F, Fujimura M, Gomez G, Salva JA, Greeley GH Jr, Thompson JC. [Cellular localization, half-life, and secretion of peptide YY]. Rev. Esp. Fisiol. 45(4), 377-384 (1989
-
(1989)
Rev. Esp. Fisiol
, vol.45
, Issue.4
, pp. 377-384
-
-
Lluis, F.1
Fujimura, M.2
Gomez, G.3
Salva, J.A.4
Greeley Jr., G.H.5
Thompson, J.C.6
-
72
-
-
0026732813
-
Extrinsic neural contribution to ileal peptide YY (PYY) release
-
Rudnicki M, Kuvshinoff BW, McFadden DW. Extrinsic neural contribution to ileal peptide YY (PYY) release. J. Surg. Res. 52(6), 591-595 (1992
-
(1992)
J. Surg. Res
, vol.52
, Issue.6
, pp. 591-595
-
-
Rudnicki, M.1
Kuvshinoff, B.W.2
McFadden, D.W.3
-
73
-
-
21344468734
-
Physiology: Does gut hormone PYY3-36 decrease food intake in rodents?
-
(reply
-
Batterham RL, Cowley MA, Small CJ et al. Physiology: Does gut hormone PYY3-36 decrease food intake in rodents? (reply). Nature 430, 6996 (2004
-
(2004)
Nature
, vol.430
, pp. 6996
-
-
Batterham, R.L.1
Cowley, M.A.2
Small, C.J.3
-
74
-
-
0041859261
-
Inhibition of food intake in obese subjects by peptide YY3
-
Batterham RL, Cohen MA, Ellis SM et al. Inhibition of food intake in obese subjects by peptide YY3. N. Engl. J. Med. 349(10), 941-948 (2003
-
(2003)
N. Engl. J. Med
, vol.349
, Issue.10
, pp. 941-948
-
-
Batterham, R.L.1
Cohen, M.A.2
Ellis, S.M.3
-
75
-
-
84856080046
-
Gut hormones and appetite control: A focus on PYY and GLP-1 as therapeutic targets in obesity
-
De SA, Bloom SR. Gut hormones and appetite control: A focus on PYY and GLP-1 as therapeutic targets in obesity. Gut Liver 6(1), 10-20 (2012
-
(2012)
Gut Liver
, vol.6
, Issue.1
, pp. 10-20
-
-
De, S.A.1
Bloom, S.R.2
-
76
-
-
27744469753
-
PYY3-36 inhibits the action potential firing activity of POMC neurons of arcuate nucleus through postsynaptic Y2 receptors
-
Ghamari-Langroudi M, Colmers WF, Cone RD. PYY3-36 inhibits the action potential firing activity of POMC neurons of arcuate nucleus through postsynaptic Y2 receptors. Cell Metab. 2(3), 191-199 (2005
-
(2005)
Cell Metab
, vol.2
, Issue.3
, pp. 191-199
-
-
Ghamari-Langroudi, M.1
Colmers, W.F.2
Cone, R.D.3
-
77
-
-
0030901415
-
Enteroglucagon
-
Holst JJ. Enteroglucagon. Ann. Rev. Physiol. 59, 257-271 (1997
-
(1997)
Ann. Rev. Physiol
, vol.59
, pp. 257-271
-
-
Holst, J.J.1
-
78
-
-
0028107226
-
The role of the gut in regulating food intake in man
-
Read N, French S, Cunningham K. The role of the gut in regulating food intake in man. Nutr. Rev. 52(1), 1-10 (1994
-
(1994)
Nutr. Rev
, vol.52
, Issue.1
, pp. 1-10
-
-
Read, N.1
French, S.2
Cunningham, K.3
-
79
-
-
0020456354
-
Evidence that enteroglucagon (II) is identical with the C-terminal sequence (residues 33-69) of glicentin
-
Holst JJ. Evidence that enteroglucagon (II) is identical with the C-terminal sequence (residues 33-69) of glicentin. Biochem. J. 207(3), 381-388 (1982
-
(1982)
Biochem. J.
, vol.207
, Issue.3
, pp. 381-388
-
-
Holst, J.J.1
-
80
-
-
0019766354
-
Bioactive Enteroglucagon (oxyntomodulin): Present knowledge on its chemical structure and its biological activities
-
Bataille D, Gespach C, Tatemoto K et al. Bioactive enteroglucagon (oxyntomodulin): Present knowledge on its chemical structure and its biological activities. Peptides 2(Suppl. 2), 41-44 (1981
-
(1981)
Peptides
, vol.2
, Issue.SUPPL. 2
, pp. 41-44
-
-
Bataille, D.1
Gespach, C.2
Tatemoto, K.3
-
81
-
-
84872175094
-
Unraveling oxyntomodulin GLP-1's enigmatic brother
-
Pocai A. Unraveling Oxyntomodulin, GLP-1's enigmatic brother. J. Endocrinology 215(3), 335-346 (2012
-
(2012)
J. Endocrinology
, vol.215
, Issue.3
, pp. 335-346
-
-
Pocai, A.1
-
82
-
-
33750628142
-
The role of oxyntomodulin and peptide tyrosine-tyrosine (PYY) in appetite control
-
Wynne K, Bloom SR. The role of oxyntomodulin and peptide tyrosine-tyrosine (PYY) in appetite control. Nat. Clin. Pract. Endocrinol. Metab. 2(11), 612-620 (2006
-
(2006)
Nat. Clin. Pract. Endocrinol. Metab
, vol.2
, Issue.11
, pp. 612-620
-
-
Wynne, K.1
Bloom, S.R.2
-
83
-
-
0021259313
-
A pure enteroglucagon, oxyntomodulin (glucagon 37), stimulates insulin release in perfused rat pancreas
-
Jarrousse C, Bataille D, Jeanrenaud B. A pure enteroglucagon, oxyntomodulin (glucagon 37), stimulates insulin release in perfused rat pancreas. Endocrinology 115(1), 102-105 (1984
-
(1984)
Endocrinology
, vol.115
, Issue.1
, pp. 102-105
-
-
Jarrousse, C.1
Bataille, D.2
Jeanrenaud, B.3
-
84
-
-
77957592532
-
The mechanism of action for oxyntomodulin in the regulation of obesity
-
Wynne K, Field BC, Bloom SR. The mechanism of action for oxyntomodulin in the regulation of obesity. Curr. Opin. Investig. Drugs 11(10), 1151-1157 (2010
-
(2010)
Curr. Opin. Investig. Drugs
, vol.11
, Issue.10
, pp. 1151-1157
-
-
Wynne, K.1
Field, B.C.2
Bloom, S.R.3
-
85
-
-
33749339257
-
Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: A randomised controlled trial
-
Wynne K, Park AJ, Small CJ et al. Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: A randomised controlled trial. Int. J. Obes. (Lond.) 30(12), 1729-1736 (2006
-
(2006)
Int. J. Obes. (Lond
, vol.30
, Issue.12
, pp. 1729-1736
-
-
Wynne, K.1
Park, A.J.2
Small, C.J.3
-
86
-
-
2542460293
-
Peripheral oxyntomodulin reduces food intake and body weight gain in rats
-
Dakin CL, Small CJ, Batterham RL et al. Peripheral oxyntomodulin reduces food intake and body weight gain in rats. Endocrinology 145(6), 2687-2695 (2004
-
(2004)
Endocrinology
, vol.145
, Issue.6
, pp. 2687-2695
-
-
Dakin, C.L.1
Small, C.J.2
Batterham, R.L.3
-
87
-
-
0034807498
-
Oxyntomodulin inhibits food intake in the rat
-
Dakin CL, Gunn I, Small CJ et al. Oxyntomodulin inhibits food intake in the rat. Endocrinology 142(10), 4244-4250 (2001
-
(2001)
Endocrinology
, vol.142
, Issue.10
, pp. 4244-4250
-
-
Dakin, C.L.1
Gunn, I.2
Small, C.J.3
-
88
-
-
84864351901
-
The glucagon receptor is involved in mediating the body weight-lowering effects of oxyntomodulin
-
Kosinski JR, Hubert J, Carrington PE et al. The glucagon receptor is involved in mediating the body weight-lowering effects of oxyntomodulin. Obes. (Silver Spring) 20(8), 1566-1571(2012
-
(2012)
Obes. (Silver Spring
, vol.20
, Issue.8
, pp. 1566-1571
-
-
Kosinski, J.R.1
Hubert, J.2
Carrington, P.E.3
-
89
-
-
70349644658
-
Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice
-
Pocai A, Carrington PE, Adams JR et al. Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice. Diabetes 58(10), 2258-2266 (2009
-
(2009)
Diabetes
, vol.58
, Issue.10
, pp. 2258-2266
-
-
Pocai, A.1
Carrington, P.E.2
Adams, J.R.3
-
90
-
-
33749368018
-
Oxyntomodulin: A novel potential treatment for obesity
-
Druce MR, Bloom SR. Oxyntomodulin: A novel potential treatment for obesity. Treat. Endocrinol. 5(5), 265-272 (2006
-
(2006)
Treat. Endocrinol
, vol.5
, Issue.5
, pp. 265-272
-
-
Druce, M.R.1
Bloom, S.R.2
-
91
-
-
0021032599
-
Mammalian pancreatic preproglucagon contains three glucagon-related peptides
-
Lopez LC, Frazier ML, Su CJ, Kumar A, Saunders GF. Mammalian pancreatic preproglucagon contains three glucagon-related peptides. Proc. Natl Acad. Sci.USA 80(18), 5485-5489 (1983
-
(1983)
Proc. Natl Acad. Sci.USA
, vol.80
, Issue.18
, pp. 5485-5489
-
-
Lopez, L.C.1
Frazier, M.L.2
Su, C.J.3
Kumar, A.4
Saunders, G.F.5
-
92
-
-
0024236086
-
Oxyntomodulin and glicentin: Brain-gut peptides in the rat
-
Blache P, Kervran A, Bataille D. Oxyntomodulin and glicentin: Brain-gut peptides in the rat. Endocrinology 123(6), 2782-2787 (1988
-
(1988)
Endocrinology
, vol.123
, Issue.6
, pp. 2782-2787
-
-
Blache, P.1
Kervran, A.2
Bataille, D.3
-
93
-
-
25844462858
-
Role of recombinant human glicentin in the normal human jejunum: An in vitro study
-
Tomita R, Igarashi S, Tanjoh K, Fujisaki S. Role of recombinant human glicentin in the normal human jejunum: An in vitro study. Hepatogastroenterology 52(65), 1459-1462 (2005
-
(2005)
Hepatogastroenterology
, vol.52
, Issue.65
, pp. 1459-1462
-
-
Tomita, R.1
Igarashi, S.2
Tanjoh, K.3
Fujisaki, S.4
-
95
-
-
0035933822
-
Activation and functional characterization of the mosaic receptor SorLA/LR11
-
Jacobsen L, Madsen P, Jacobsen C, Nielsen MS, Gliemann J, Petersen CM. Activation and functional characterization of the mosaic receptor SorLA/LR11. J. Biol. Chem. 276(25), 22788-22796 (2001
-
(2001)
J. Biol. Chem
, vol.276
, Issue.25
, pp. 22788-22796
-
-
Jacobsen, L.1
Madsen, P.2
Jacobsen, C.3
Nielsen, M.S.4
Gliemann, J.5
Petersen, C.M.6
-
96
-
-
33748742627
-
Effect of gastric bypass and gastric banding on neurotensin levels in morbidly obese patients
-
Christ-Crain M, Stoeckli R, Ernst A et al Effect of gastric bypass and gastric banding on neurotensin levels in morbidly obese patients. J. Clin. Endocrinol. Metab. 91(9), 3544-3547 (2006
-
(2006)
J. Clin. Endocrinol. Metab
, vol.91
, Issue.9
, pp. 3544-3547
-
-
Christ-Crain, M.1
Stoeckli, R.2
Ernst, A.3
-
97
-
-
0026510891
-
Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man
-
Eissele R, Goke R, Willemer S et al. Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man. Eur. J. Clin. Invest. 22(4), 283-291 (1992
-
(1992)
Eur. J. Clin. Invest
, vol.22
, Issue.4
, pp. 283-291
-
-
Eissele, R.1
Goke, R.2
Willemer, S.3
-
99
-
-
0028575660
-
Activation of proglucagon gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line
-
Drucker DJ, Jin T, Asa SL, Young TA, Brubaker PL. Activation of proglucagon gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line. Mol. Endocrinol. 8(12), 1646-1655 (1994
-
(1994)
Mol. Endocrinol
, vol.8
, Issue.12
, pp. 1646-1655
-
-
Drucker, D.J.1
Jin, T.2
Asa, S.L.3
Young, T.A.4
Brubaker, P.L.5
-
100
-
-
0025296197
-
Development of neuroendocrine tumors in the gastrointestinal tract of transgenic mice Heterogeneity of hormone expression
-
Rindi G, Grant SG, Yiangou Y et al. Development of neuroendocrine tumors in the gastrointestinal tract of transgenic mice. Heterogeneity of hormone expression. Am. J. Pathol. 136(6), 1349-1363 (1990
-
(1990)
Am. J. Pathol
, vol.136
, Issue.6
, pp. 1349-1363
-
-
Rindi, G.1
Grant, S.G.2
Yiangou, Y.3
-
101
-
-
56449093424
-
Glucose sensing in L cells: A primary cell study
-
Reimann F, Habib AM, Tolhurst G, Parker HE, Rogers GJ, Gribble FM. glucose sensing in L cells: A primary cell study. Cell Metab. 8(6), 532-539 (2008
-
(2008)
Cell Metab
, vol.8
, Issue.6
, pp. 532-539
-
-
Reimann, F.1
Habib, A.M.2
Tolhurst, G.3
Parker, H.E.4
Rogers, G.J.5
Gribble, F.M.6
-
102
-
-
84862604197
-
Changes in gastrointestinal hormone responses, insulin sensitivity, and beta-cell function within 2 weeks after gastric bypass in non-diabetic subjects
-
Jacobsen SH, Olesen SC, Dirksen C et al. Changes in gastrointestinal hormone responses, insulin sensitivity, and beta-cell function within 2 weeks after gastric bypass in non-diabetic subjects. Obes. Surg. 22(7), 1084-1096 (2012
-
(2012)
Obes. Surg
, vol.22
, Issue.7
, pp. 1084-1096
-
-
Jacobsen, S.H.1
Olesen, S.C.2
Dirksen, C.3
-
103
-
-
84555186977
-
Na+-d-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion
-
Gorboulev V, Schürmann A, Vallon V et al. Na+-d-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes 61(1), 187-196 (2012
-
(2012)
Diabetes
, vol.61
, Issue.1
, pp. 187-196
-
-
Gorboulev, V.1
Schürmann, A.2
Vallon, V.3
-
104
-
-
84866065884
-
Predominant role of active versus facilitative glucose transport for glucagon-like peptide- 1 secretion
-
Parker HE, Adriaenssens A, Rogers G et al. Predominant role of active versus facilitative glucose transport for glucagon-like peptide- 1 secretion. Diabetologia 55(9), 2445-2455 (2012
-
(2012)
Diabetologia
, vol.55
, Issue.9
, pp. 2445-2455
-
-
Parker, H.E.1
Adriaenssens, A.2
Rogers, G.3
-
105
-
-
84860436360
-
Nutrient detection by incretin hormone secreting cells
-
Diakogiannaki E, Gribble FM, Reimann F. Nutrient detection by incretin hormone secreting cells. Physiol. Behav. 106(3), 387-393 (2012
-
(2012)
Physiol. Behav
, vol.106
, Issue.3
, pp. 387-393
-
-
Diakogiannaki, E.1
Gribble, F.M.2
Reimann, F.3
-
106
-
-
68049106367
-
Stimulation of incretin secretion by dietary lipid: Is it dose dependent?
-
Yoder SM, Yang Q, Kindel TL, Tso P. Stimulation of incretin secretion by dietary lipid: Is it dose dependent? Am. J. Physiol. Gastrointest. Liver Physiol. 297(2), G299-G305 (2009
-
(2009)
Am J. Physiol. Gastrointest. Liver Physiol
, vol.297
, Issue.2
-
-
Yoder, S.M.1
Yang, Q.2
Kindel, T.L.3
Tso, P.4
-
107
-
-
0029352151
-
Postprandial lipid and hormone responses to meals of varying fat contents: Modulatory role of lipoprotein lipase?
-
Murphy MC, Isherwood SG, Sethi S et al. Postprandial lipid and hormone responses to meals of varying fat contents: Modulatory role of lipoprotein lipase? Eur. J. Clin. Nutr. 49(8), 578-588 (1995
-
(1995)
Eur J. Clin. Nutr
, vol.49
, Issue.8
, pp. 578-588
-
-
Murphy, M.C.1
Isherwood, S.G.2
Sethi, S.3
-
108
-
-
56749154840
-
A gut feeling for obesity: 7TM sensors on enteroendocrine cells
-
Engelstoft MS, Egerod KL, Holst B, Schwartz TW. A gut feeling for obesity: 7TM sensors on enteroendocrine cells. Cell Metab. 8(6), 447-449 (2008
-
(2008)
Cell Metab
, vol.8
, Issue.6
, pp. 447-449
-
-
Engelstoft, M.S.1
Egerod, K.L.2
Holst, B.3
Schwartz, T.W.4
-
109
-
-
42449126696
-
A role for intestinal endocrine cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucagon-like peptide- 1 and glucose-dependent insulinotropic peptide release
-
Chu ZL, Carroll C, Alfonso J et al. A role for intestinal endocrine cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucagon-like peptide- 1 and glucose-dependent insulinotropic peptide release. Endocrinol. 149(5), 2038-2047 (2008
-
(2008)
Endocrinol
, vol.149
, Issue.5
, pp. 2038-2047
-
-
Chu, Z.L.1
Carroll, C.2
Alfonso, J.3
-
110
-
-
0035829625
-
An anorexic lipid mediator regulated by feeding
-
Rodriguez de Fonseca F, Navarro M, Gomez R et al. An anorexic lipid mediator regulated by feeding. Nature 414(6860), 209-212 (2001
-
(2001)
Nature
, vol.414
, Issue.6860
, pp. 209-212
-
-
Rodriguez De Fonseca, F.1
Navarro, M.2
Gomez, R.3
-
111
-
-
80052521074
-
2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans
-
Hansen KB, Rosenkilde MM, Knop FK et al. 2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans. J. Clin. Endocrinol. Metab. 96(9), E1409-E1417 (2011
-
(2011)
J. Clin. Endocrinol. Metab
, vol.96
, Issue.9
-
-
Hansen, K.B.1
Rosenkilde, M.M.2
Knop, F.K.3
-
112
-
-
33644627958
-
Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents
-
Overton HA, Babbs AJ, Doel SM et al. Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. Cell Metab. 3(3), 167-175 (2006
-
(2006)
Cell Metab
, vol.3
, Issue.3
, pp. 167-175
-
-
Overton, H.A.1
Babbs, A.J.2
Doel, S.M.3
-
113
-
-
83755220083
-
Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion
-
Parker HE, Wallis K, le Roux CW, Wong KY, Reimann F, Gribble FM. Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion. Br. J. Pharmacol. 165(2), 414-423 (2012
-
(2012)
Br. J. Pharmacol
, vol.165
, Issue.2
, pp. 414-423
-
-
Parker, H.E.1
Wallis, K.2
Le Roux, C.W.3
Wong, K.Y.4
Reimann, F.5
Gribble, F.M.6
-
114
-
-
84871097990
-
Effect of bile acid sequestrants on glycaemic control: Protocol for a systematic review with meta-analysis of randomised controlled trials
-
Hansen M, Sonne DP, Mikkelsen KH, Gluud LL, Vilsböll T, Knop FK. Effect of bile acid sequestrants on glycaemic control: Protocol for a systematic review with meta-analysis of randomised controlled trials. BMJ Open 2(6) (2012
-
(2012)
BMJ Open
, vol.2
, Issue.6
-
-
Hansen, M.1
Sonne, D.P.2
Mikkelsen, K.H.3
Gluud, L.L.4
Vilsböll, T.5
Knop, F.K.6
-
115
-
-
33751069321
-
Meat hydrolysate and essential amino acid-induced glucagon-like peptide-1 secretion, in the human NCI-H716 enteroendocrine cell line, is regulated by extracellular signal-regulated kinase1/2 and p38 mitogen-activated protein kinases
-
Reimer RA. Meat hydrolysate and essential amino acid-induced glucagon-like peptide-1 secretion, in the human NCI-H716 enteroendocrine cell line, is regulated by extracellular signal-regulated kinase1/2 and p38 mitogen-activated protein kinases. J. Endocrinol. 191(1), 159-170 (2006
-
(2006)
J. Endocrinol
, vol.191
, Issue.1
, pp. 159-170
-
-
Reimer, R.A.1
-
116
-
-
0031750108
-
Peptones stimulate both the secretion of the incretin hormone glucagon-like peptide 1 and the transcription of the proglucagon gene
-
Cordier-Bussat M, Bernard C, Levenez F et al. Peptones stimulate both the secretion of the incretin hormone glucagon-like peptide 1 and the transcription of the proglucagon gene. Diabetes 47(7), 1038-1045 (1998
-
(1998)
Diabetes
, vol.47
, Issue.7
, pp. 1038-1045
-
-
Cordier-Bussat, M.1
Bernard, C.2
Levenez, F.3
-
117
-
-
75349091535
-
Molecular mechanisms underlying nutrient detection by incretin-secreting cells
-
Reimann F. Molecular mechanisms underlying nutrient detection by incretin-secreting cells. Int. Dairy J. 20(4), 236-242 (2010
-
(2010)
Int. Dairy J.
, vol.20
, Issue.4
, pp. 236-242
-
-
Reimann, F.1
-
118
-
-
5644240984
-
Glutamine potently stimulates glucagon-like peptide- 1 secretion from GLUTag cells
-
Reimann F, Williams L, Silva Xavier G, Rutter GA, Gribble FM. Glutamine potently stimulates glucagon-like peptide- 1 secretion from GLUTag cells. Diabetologia 47(9), 1592-1601 (2004
-
(2004)
Diabetologia
, vol.47
, Issue.9
, pp. 1592-1601
-
-
Reimann, F.1
Williams, L.2
Silva Xavier, G.3
Rutter, G.A.4
Gribble, F.M.5
-
119
-
-
58149373780
-
Oral glutamine increases circulating glucagon-like peptide 1, glucagon, and insulin concentrations in lean, obese, and type 2 diabetic subjects
-
Greenfield JR, Farooqi IS, Keogh JM et al. Oral glutamine increases circulating glucagon-like peptide 1, glucagon, and insulin concentrations in lean, obese, and type 2 diabetic subjects. Am. J. Clin. Nutr. 89(1), 106-113 (2009
-
(2009)
Am. J. Clin. Nutr
, vol.89
, Issue.1
, pp. 106-113
-
-
Greenfield, J.R.1
Farooqi, I.S.2
Keogh, J.M.3
-
120
-
-
84864146681
-
LX4211, a dual SGLT1/SGLT2 inhibitor, improved glycemic control in patients with type 2 diabetes in a randomized, placebo-controlled trial
-
Zambrowicz B, Freiman J, Brown PM et al. LX4211, a dual SGLT1/SGLT2 inhibitor, improved glycemic control in patients with type 2 diabetes in a randomized, placebo-controlled trial. Clin. Pharmacol. Ther. 92(2), 158-169 (2012
-
(2012)
Clin. Pharmacol. Ther
, vol.92
, Issue.2
, pp. 158-169
-
-
Zambrowicz, B.1
Freiman, J.2
Brown, P.M.3
-
121
-
-
84874977086
-
Effects of LX4211, a dual SGLT1/ SGLT2 inhibitor, plus sitagliptin on postprandial active GLP-1 and glycemic control in type 2 diabetes
-
Zambrowicz B, Ding ZM, Ogbaa I et al. Effects of LX4211, a dual SGLT1/ SGLT2 inhibitor, plus sitagliptin on postprandial active GLP-1 and glycemic control in type 2 diabetes. Clin. Ther. 35(3), 273-285 (2013
-
(2013)
Clin. Ther
, vol.35
, Issue.3
, pp. 273-285
-
-
Zambrowicz, B.1
Ding, Z.M.2
Ogbaa, I.3
-
122
-
-
84876519168
-
LX4211 Increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1 (SGLT1)- mediated absorption of intestinal glucose
-
Powell DR, Smith M, Greer J et al. LX4211 Increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1 (SGLT1)- mediated absorption of intestinal glucose. J. Pharmacol. Exp. Ther. 345(2), 250-259 (2013
-
(2013)
J. Pharmacol. Exp. Ther
, vol.345
, Issue.2
, pp. 250-259
-
-
Powell, D.R.1
Smith, M.2
Greer, J.3
-
123
-
-
84864118760
-
KGA-2727, a novel selective inhibitor of a high-affinity sodium glucose cotransporter (SGLT1), exhibits antidiabetic efficacy in rodent models
-
Shibazaki T, Tomae M, Ishikawa-Takemura Y et al. KGA-2727, a novel selective inhibitor of a high-affinity sodium glucose cotransporter (SGLT1), exhibits antidiabetic efficacy in rodent models. J. Pharmacol. Exp. Ther. 342(2), 288-296 (2012
-
(2012)
J. Pharmacol. Exp. Ther
, vol.342
, Issue.2
, pp. 288-296
-
-
Shibazaki, T.1
Tomae, M.2
Ishikawa-Takemura, Y.3
-
124
-
-
80054988309
-
Pharmacokinetics, pharmacodynamics, safety, and tolerability of JNJ-38431055, a novel GPR119 receptor agonist and potential antidiabetes agent, in healthy male subjects
-
Katz LB, Gambale JJ, Rothenberg PL et al. Pharmacokinetics, pharmacodynamics, safety, and tolerability of JNJ-38431055, a novel GPR119 receptor agonist and potential antidiabetes agent, in healthy male subjects. Clin. Pharmacol. Ther. 90(5), 685-692 (2011
-
(2011)
Clin. Pharmacol. Ther
, vol.90
, Issue.5
, pp. 685-692
-
-
Katz, L.B.1
Gambale, J.J.2
Rothenberg, P.L.3
-
125
-
-
79951636303
-
GPR119 regulates murine glucose homeostasis through incretin receptor-dependent and independent mechanisms
-
Flock G, Holland D, Seino Y, Drucker DJ. GPR119 regulates murine glucose homeostasis through incretin receptor-dependent and independent mechanisms. Endocrinology 152(2), 374-383 (2011
-
(2011)
Endocrinology
, vol.152
, Issue.2
, pp. 374-383
-
-
Flock, G.1
Holland, D.2
Seino, Y.3
Drucker, D.J.4
-
126
-
-
69149083245
-
TGR5-mediated bile acid sensing controls glucose homeostasis
-
Thomas C, Gioiello A, Noriega L et al. TGR5-mediated bile acid sensing controls glucose homeostasis. Cell Metab. 10(3), 167-177 (2009
-
(2009)
Cell Metab
, vol.10
, Issue.3
, pp. 167-177
-
-
Thomas, C.1
Gioiello, A.2
Noriega, L.3
-
127
-
-
77249142314
-
Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1
-
Shang Q, Saumoy M, Holst JJ, Salen G, Xu G. Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1. Am. J. Physiol. Gastrointest. Liver Physiol. 298(3), G419-G424 (2010
-
(2010)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.298
, Issue.3
-
-
Shang, Q.1
Saumoy, M.2
Holst, J.J.3
Salen, G.4
Xu, G.5
-
128
-
-
84866125785
-
Rectal taurocholate increases L cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers
-
Adrian TE, Gariballa S, Parekh KA et al. Rectal taurocholate increases L cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers. Diabetologia 55(9), 2343-2347 (2012
-
(2012)
Diabetologia
, vol.55
, Issue.9
, pp. 2343-2347
-
-
Adrian, T.E.1
Gariballa, S.2
Parekh, K.A.3
-
129
-
-
84875054928
-
Activation of FFA1 mediates GLP-1 secretion in mice evidence for allosterism at FFA1
-
Xiong Y, Swaminath G, Cao Q et al. Activation of FFA1 mediates GLP-1 secretion in mice. Evidence for allosterism at FFA1. Mol. Cell. Endocrinol. 369(1-2), 119-129 (2013
-
(2013)
Mol. Cell. Endocrinol
, vol.369
, Issue.1-2
, pp. 119-129
-
-
Xiong, Y.1
Swaminath, G.2
Cao, Q.3
-
130
-
-
84867290314
-
A Potent class of GPR40 full agonists engages the enteroinsular axis to promote glucose control in rodents
-
Luo J, Swaminath G, Brown SP et al. A Potent class of GPR40 full agonists engages the enteroinsular axis to promote glucose control in rodents. PLoS ONE 7(10), e46300 (2012
-
(2012)
PLoS ONE
, vol.7
, Issue.10
-
-
Luo, J.1
Swaminath, G.2
Brown, S.P.3
-
131
-
-
84865383561
-
Synergism by individual macronutrients explains the marked early GLP-1 and islet hormone responses to mixed meal challenge in mice
-
Ahlkvist L, Vikman J, Pacini G, Ahren B. Synergism by individual macronutrients explains the marked early GLP-1 and islet hormone responses to mixed meal challenge in mice. Regul. Pep. 178(1-3), 29-35 (2012
-
(2012)
Regul. Pep
, vol.178
, Issue.1-3
, pp. 29-35
-
-
Ahlkvist, L.1
Vikman, J.2
Pacini, G.3
Ahren, B.4
-
132
-
-
78449274342
-
Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1
-
Migoya EM, Bergeron R, Miller JL et al. Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1. Clin. Pharmacol. Ther. 88(6), 801-808 (2010
-
(2010)
Clin. Pharmacol. Ther
, vol.88
, Issue.6
, pp. 801-808
-
-
Migoya, E.M.1
Bergeron, R.2
Miller, J.L.3
|