Stimulation of incretin secretion by dietary lipid: Is it dose dependent?

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 297, Issue 2, 2009, Pages

  Yoder, Stephanie M ^a   Yang, Qing ^a   Kindel, Tammy L ^a   Tso, Patrick ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Enteroendocrine cells; Glucagon like peptide 1; Glucose dependent insulinotropic polypeptide; Lipid induced incretin secretion; Lymph

Indexed keywords

GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON LIKE PEPTIDE 1; INCRETIN; ISOFLURANE; LIPID; LIPID EMULSION; LIPOSYN II; SODIUM CHLORIDE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ARTICLE; CALORIC INTAKE; CELL TYPE; CONTROLLED STUDY; ENTEROENDOCRINE CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FAT INTAKE; INTESTINE MOTILITY; LIPID ABSORPTION; LYMPH VESSEL; MALE; NONHUMAN; NUTRIENT; PRIORITY JOURNAL; RAT; SECRETORY CELL;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DUODENUM; ENTEROENDOCRINE CELLS; FAT EMULSIONS, INTRAVENOUS; FEEDBACK, BIOCHEMICAL; GASTRIC INHIBITORY POLYPEPTIDE; GASTROINTESTINAL MOTILITY; GLUCAGON-LIKE PEPTIDE 1; INCRETINS; INTESTINAL ABSORPTION; INTUBATION, GASTROINTESTINAL; LYMPH; MALE; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; TRIGLYCERIDES;

EID: 68049106367     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.90601.2008     Document Type: Article

References (36)

1. Baggio LL, Drucker DJ. Biology of incretins: GLP-1 and GIP. Gastroenterology 132: 2131-2157, 2007.
2. Besterman HS, Cook GC, Sarson DL, Christofides ND, Bryant MG, Gregor M, Bloom SR. Gut hormones in tropical malabsorption. Br Med J 2: 1252-1255, 1979.
3. Bollman JL. A cage which limits the activity of rats. J Lab Clin Med 33: 1348, 1948.
4. Bollman JL, Cain JC, Grindlay JH. Techniques for the collection of lymph from the liver, small intestine, or thoracic duct of the rat. J Lab Clin Med 33: 1349-1352, 1948.
5. Booth CC, Read AE, Jones E. Studies on the site of fat absorption: the sites of absorption of increasing doses of 131I-labelled triolein in the rat. Gut 2: 23-31, 1961.
6. Chu Z, Carroll C, Alfonso J, Gutierrez V, He H, Lucman A, Pedraza M, Mondala H, Gao H, Bagnol D, Chen R, Jones RM, Behan DP, Leonard J. A role for intestinal endocrine cell-expressed G proteincoupled receptor 119 in glycemic control by enhancing glucagon-like peptide-1 and glucose-dependent insulinotropic peptide release. Endocrinology 149: 2038-2047, 2008.
7. D'Alessio D, Lu W, Sun W, Zheng S, Yang Q, Seeley R, Woods SC, Tso P. Fasting and postprandial concentrations of glucagon-like peptide 1 in intestinal lymph and portal plasma: evidence for selective release of GLP-1 into the lymph system. Am J Physiol Regul Integr Comp Physiol 293: R2163-R2169, 2007.
8. Deacon CF. What do we know about the secretion and degradation of incretin hormones? Regul Pept 128: 117-124, 2005.
9. Fukase N, Takahashi H, Manaka H, Igarashi M, Yamatani K, Daimon M, Sugiyama K, Tominaga M, Sasaki H. Differences in glucagon-like peptide-1 and GIP responses following sucrose ingestion. Diabetes Res Clin Pract 15: 187-195, 1992.
10. Fushiki T, Kojima A, Imoto T, Inoue K, Sugimoto E. An extract of Gymnema sylvestre leaves and purified gymnemic acid inhibits glucosestimulated gastric inhibitory peptide secretion in rats. J Nutr 122: 2367-2373, 1992.
11. Gutzwiller JP, Göke B, Drewe J, Hildebrand P, Ketterer S, Handschin D, Winterhalder R, Conen D, Beglinger C. Glucagon-like peptide-1: a potent regulator of food intake in humans. Gut 44: 81-86, 1999.
12. Hirasawa A, Tsumaya K, Awaji T, Katsuma S, Adachi T, Yamada M, Sugimoto Y, Miyazaki S, Tsujimoto G. Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. Nat Med 11: 90-94, 2005.
13. Iakoubov R, Izzo A, Yeung A, Whiteside CI, Brubaker PL. Protein kinase C is required for oleic acid-induced secretion of glucagon-like peptide-1 by intestinal endocrine L cells. Endocrinology 148: 1089-1098, 2007.
14. Jang H, Kokrashvili Z, Theodorakis MJ, Carlson OD, Kim B, Zhou J, Kim HH, Xu X, Chan SL, Juhaszova M, Bernier M, Mosinger B, Margolskee RF, Egan JM. Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1. Proc Natl Acad Sci USA 104: 15069-15074, 2007.
15. Karhunen LJ, Juvonen KR, Huotari A, Purhonen AK, Herzig KH. Effect of protein, fat, carbohydrate and fibre on gastrointestinal peptide release in humans. Regul Pept 149: 70-78, 2008.
16. Larsen PJ, Fledelius C, Knudsen LB, Tang-Christensen M. Systemic administration of the long-acting GLP-1 derivative NN2211 induced lasting and reversible weight loss in both normal and obese rats. Diabetes 50: 2530-2539, 2001.
17. Layer P, Peschel S, Schlesinger T, Goebell H. Human pancreatic secretion and intestinal motility: effects of ileal nutrient perfusion. Am J Physiol Gastrointest Liver Physiol 258: G196-G201, 1990.
18. Lu WJ, Yang Q, Sun W, Woods SC, D'Alessio D, Tso P. The regulation of the lymphatic secretion of glucagon-like peptide-1 (GLP-1) by intestinal absorption of fat and carbohydrate. Am J Physiol Gastrointest Liver Physiol 293: G963-G971, 2007.
19. Lu WJ, Yang Q, Sun W, Woods SC, D'Alessio D, Tso P. Using the lymph fistula rat model to study the potentiation of GIP secretion by the ingestion of fat and glucose. Am J Physiol Gastrointest Liver Physiol 294: G1130-G1138, 2008.
20. Maljaars PWJ, Peters HPF, Mela DJ, Masclee AAM. Ileal brake: a sensible food target for appetite control. Physiol Behav 95: 271-281, 2008.
21. +-glucose cotransporter 1. Proc Natl Acad Sci USA 104: 15075-15080, 2007.
22. Mentlein R, Gallwitz B, Schmidt WE. Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1 (7-36)amide, peptide histidine methionine, and is responsible for their degradation in human serum. Eur J Biochem 214: 829-835, 1993.
23. Mortensten K, Christensen LL, Holst JJ, Orskov C. GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine. Regul Pept 114: 189-196, 2003.
24. Nauck MA, Niedereichholz U, Ettler R, Holst JJ, ∅rskov C, Ritzel R, Schmiegel WH. Glucgaon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans. Am J Physiol Endocrinol Metab 273: E981-E988, 1997.
25. Näslund E, Barkeling B, King N, Gutniak M, Blundell JE, Holst JJ, Rössner S, Hellström PM. Energy intake and appetite are suppressed by glucagon-like peptide-1 (GLP-1) in obese men. Int J Obes 23: 304-311, 1999.
26. Perley MJ, Kipnis DM. Plasma insulin response to oral and intravenous glucose: studies in normal and diabetic subjects. J Clin Invest 46: 1954-1962, 1967.
27. Rocca AS, Brubaker PL. Stereospecific effects of fatty acids on proglucagon-derived peptide secretion in fetal rat intestinal cultures. Endocrinology 136: 5593-5599, 1995.
28. Rodriguez MD, Kalogeris TJ, Wang XL, Wolf R, Tso P. Rapid synthesis and secretion of intestinal apolipoprotein A-IV after gastric fat loading in rats. Am J Physiol Regul Integr Comp Physiol 272: R1170-R1177, 1997.
29. Spiller RC, Trotman IF, Adrian TE, Bloom SR, Misiewicz JJ, Silk DBA. Further characterization of the "ileal brake" reflex in man - effect of ileal infusion of partial digests of fat, protein, and starch on jejunal motility and release of neurotensin, enteroglucagon, and peptide YY. Gut 29: 1042-1051, 1988.
30. Spiller RC, Trotman IF, Higgins BE, Ghatei MA, Grimble GK, Lee YC, Bloom SR, Misiewicz JJ, Silk DBA. The ileal brake - inhibition of jejunal motility after ileal fat perfusion in man. Gut 25: 365-374, 1984.
31. Theodorakis MJ, Carlson O, Michopoulos S, Doyle ME, Juhaszova M, Petraki K, Egan JM. Human duodenal enteroendocrine cells: source of both incretin peptides, GLP-1 and GIP. Am J Physiol Endocrinol Metab 290: E550-E559, 2006.
32. Turton MD, O'Shea D, Gunn I, Beak SA, Edwards CMB, Meeran K, Choi SJ, Taylor GM, Heath MM, Lambert PD, Wilding JPH, Smith DM, Ghatei MA, Herbert J, Bloom SR. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 379: 69-72, 1996.
33. Vilsbøll T, Krarup T, Deacon CF, Madsbad S, Holst JJ. Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients. Diabetes 50: 609-613, 2001.
34. Vilsbøll T, Krarup J, Sonne S, Madsbad A, Vølund AG, Holst JJ. Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus. J Clin Endocrinol Metab 88: 2706-2713, 2003.
35. Wang Y, Montrose-Rafizadeh C, Adams L, Raygada M, Nadiv O, Egan JM. GIP regulates glucose transporters, hexokinases, and glucoseinduced insulin secretion in RIN 1046-38 cells. Endocrinology 116: 81-87, 1996.
36. Xiao Q, Boushey RP, Drucker DJ, Brubaker PL. Secretion of the intestinotropic hormone glucagon-like peptide 2 is differentially regulated by nutrients in humans. Gastroenterology 117: 99-105, 1999.