Rectal taurocholate increases L cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers

Diabetologia

Volumn 55, Issue 9, 2012, Pages 2343-2347

  Adrian, T E ^a   Gariballa, S ^a   Parekh, K A ^a   Thomas, S A ^a   Saadi, H ^a   Al Kaabi, J ^a   Nagelkerke, N ^a   Gedulin, B ^b   Young, A A ^c  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b Satiogen Pharmaceuticals   (United States)

^c GLAXOSMITHKLINE   (United States)

Author keywords

Bile salts; Enteroendocrine; GLP 1; PYY

Indexed keywords

GLUCAGON LIKE PEPTIDE 1; GLUCOSE; INSULIN; PEPTIDE YY; PLACEBO; SITAGLIPTIN; TAUROCHOLIC ACID;

ABDOMINAL PAIN; ADULT; ANTIDIABETIC ACTIVITY; ARTICLE; BLOATING; CALORIC INTAKE; CLINICAL ARTICLE; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE INCREASE; DRUG INDUCED HEADACHE; DRUG MECHANISM; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HORMONE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; INSULIN RELEASE; L CELL; LOOSE FECES; MALE; MICTURITION DISORDER; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; RECTAL IRRITATION; RECTUM DISEASE; SINGLE BLIND PROCEDURE;

ADULT; BLOOD GLUCOSE; BODY MASS INDEX; CHOLAGOGUES AND CHOLERETICS; DIABETES MELLITUS, TYPE 2; EATING; ENTEROENDOCRINE CELLS; GLUCAGON-LIKE PEPTIDE 1; HUMANS; INSULIN; MALE; MIDDLE AGED; OBESITY; PEPTIDE YY; RECTUM; TAUROCHOLIC ACID; UNITED ARAB EMIRATES;

EID: 84866125785     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2593-2     Document Type: Article

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