SCOPUS 정보 검색 플랫폼

Volumn 143, Issue 2, 2014, Pages 289-307

Aromatic-aromatic interactions between residues in KCa3.1 pore helix and S5 transmembrane segment control the channel gating process

(6) Garneau, Line a Klein, Hélène a Lavoie, Marie France a Brochiero, Emmanuelle b,c Parent, Lucie a Sauvé, Rémy a

a Department of Physiology and Membrane Protein Research Group ^* (Canada)

b CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL (Canada)

c UNIVERSITÉ DE MONTRÉAL (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; KCNN4 PROTEIN, HUMAN;

ANIMAL; ARTICLE; CHANNEL GATING; CHEMISTRY; FEMALE; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; XENOPUS LAEVIS;

ANIMALS; FEMALE; HUMANS; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; ION CHANNEL GATING; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; XENOPUS LAEVIS;

EID: 84893123362 PISSN: 00221295 EISSN: 15407748 Source Type: Journal
DOI: 10.1085/jgp.201311097 Document Type: Article

Times cited : (13)

References (57)

1
- 5144221655
- New insights on the voltage dependence of the KCa3.1 channel block by internal TBA
- Banderali, U., H. Klein, L. Garneau, M. Simoes, L. Parent, and R. Sauvé. 2004. New insights on the voltage dependence of the KCa3.1 channel block by internal TBA. J. Gen. Physiol. 124: 333-348. http://dx.doi.org/10.1085/jgp.200409145
- (2004) J. Gen. Physiol. , vol.124 , pp. 333-348
- Banderali, U.¹ Klein, H.² Garneau, L.³ Simoes, M.⁴ Parent, L.⁵ Sauvé, R.⁶

2
- 70350344966
- + channels K(Ca)3.1 and K(v)1.3 as novel targets for asthma therapy
- + channels K(Ca)3.1 and K(v)1.3 as novel targets for asthma therapy. Br. J. Pharmacol. 157: 1330-1339. http://dx.doi.org/10.1111/j.1476-5381.2009.00362.x
- (2009) Br. J. Pharmacol. , vol.157 , pp. 1330-1339
- Bradding, P.¹ Wulff, H.²

3
- 36549082819
- + channels
- + channels. J. Gen. Physiol. 130:601-610. http:// dx.doi.org/10.1085/jgp.200709828
- (2007) J. Gen. Physiol. , vol.130 , pp. 601-610
- Bruening-Wright, A.¹ Lee, W.S.² Adelman, J.P.³ Maylie, J.⁴

4
- 78650939755
- KCNQ1 channels voltage dependence through a voltagedependent binding of the S4-S5 linker to the pore domain
- Choveau, F.S., N. Rodriguez, F. Abderemane Ali, A.J. Labro, T. Rose, S. Dahimène, H. Boudin, C. Le Hénaff, D. Escande, D.J. Snyders, et al. 2011. KCNQ1 channels voltage dependence through a voltagedependent binding of the S4-S5 linker to the pore domain. J. Biol. Chem. 286:707-716. http://dx.doi.org/10.1074/jbc.M110.146324
- (2011) J. Biol. Chem. , vol.286 , pp. 707-716
- Choveau, F.S.¹ Rodriguez, N.² Abderemane Ali, F.³ Labro, A.J.⁴ Rose, T.⁵ Dahimène, S.⁶ Boudin, H.⁷ Le Hénaff, C.⁸ Escande, D.⁹ Snyders, D.J.¹⁰

5
- 77953714921
- Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels
- Clarke, O.B., A.T. Caputo, A.P. Hill, J.I. Vandenberg, B.J. Smith, and J.M. Gulbis. 2010. Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels. Cell. 141:1018-1029. http://dx.doi.org/10.1016/j.cell.2010.05.003
- (2010) Cell. , vol.141 , pp. 1018-1029
- Clarke, O.B.¹ Caputo, A.T.² Hill, A.P.³ Vandenberg, J.I.⁴ Smith, B.J.⁵ Gulbis, J.M.⁶

6
- 40349085541
- Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel
- USA.
- Clayton, G.M., S. Altieri, L. Heginbotham, V.M. Unger, and J.H. Morais-Cabral. 2008. Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel. Proc. Natl. Acad. Sci. USA. 105:1511-1515. http://dx.doi.org/10.1073/pnas.0711533105
- (2008) Proc. Natl. Acad. Sci. , vol.105 , pp. 1511-1515
- Clayton, G.M.¹ Altieri, S.² Heginbotham, L.³ Unger, V.M.⁴ Morais-Cabral, J.H.⁵

7
- 35848958366
- Molecular driving forces determining potassium channel slow inactivation
- Cordero-Morales, J.F., V. Jogini, A. Lewis, V. Vásquez, D.M. Cortes, B. Roux, and E. Perozo. 2007. Molecular driving forces determining potassium channel slow inactivation. Nat. Struct. Mol. Biol. 14:1062-1069. http://dx.doi.org/10.1038/nsmb1309
- (2007) Nat. Struct. Mol. Biol. , vol.14 , pp. 1062-1069
- Cordero-Morales, J.F.¹ Jogini, V.² Lewis, A.³ Vásquez, V.⁴ Cortes, D.M.⁵ Roux, B.⁶ Perozo, E.⁷

8
- 33750019000
- + channels are required for human lung mast cell migration
- + channels are required for human lung mast cell migration. Thorax. 61:880-885. http://dx.doi.org/10.1136/ thx.2006.060319
- (2006) Thorax. , vol.61 , pp. 880-885
- Cruse, G.¹ Duffy, S.M.² Brightling, C.E.³ Bradding, P.⁴

9
- 81555229242
- Pharmacological activation of KCa3. 1/KCa2.3 channels produces endothelial hyperpolarization and lowers blood pressure in conscious dogs
- Damkjaer, M., G. Nielsen, S. Bodendiek, M. Staehr, J.B. Gramsbergen, C. de Wit, B.L. Jensen, U. Simonsen, P. Bie, H. Wulff, and R. Köhler. 2012. Pharmacological activation of KCa3.1/KCa2.3 channels produces endothelial hyperpolarization and lowers blood pressure in conscious dogs. Br. J. Pharmacol. 165:223-234. http:// dx.doi.org/10.1111/j.1476-5381.2011.01546.x
- (2012) Br. J. Pharmacol. , vol.165 , pp. 223-234
- Damkjaer, M.¹ Nielsen, G.² Bodendiek, S.³ Staehr, M.⁴ Gramsbergen, J.B.⁵ de Wit, C.⁶ Jensen, B.L.⁷ Simonsen, U.⁸ Bie, P.⁹ Wulff, H.¹⁰ Köhler, R.¹¹

10
- 84962463344
- Theoretical study on the polar hydrogen-pi (Hp-pi) interactions between protein side chains
- Du, Q.S., Q.Y. Wang, L.Q. Du, D. Chen, and R.B. Huang. 2013. Theoretical study on the polar hydrogen-pi (Hp-pi) interactions between protein side chains. Chem. Cent. J. 7:92. http://dx.doi.org/10 .1186/1752-153X-7-92
- (2013) Chem. Cent. J. , vol.7 , pp. 92
- Du, Q.S.¹ Wang, Q.Y.² Du, L.Q.³ Chen, D.⁴ Huang, R.B.⁵

11
- 35748931462
- Endothelium-dependent hyperpolarizations: past beliefs and present facts
- Félétou, M., and P.M. Vanhoutte. 2007. Endothelium-dependent hyperpolarizations: past beliefs and present facts. Ann. Med. 39:495- 516. http://dx.doi.org/10.1080/07853890701491000
- (2007) Ann. Med. , vol.39
- Félétou, M.¹ Vanhoutte, P.M.²

12
- 33744951682
- + channel
- + channel. J. Biol. Chem. 281:12858-12864. http://dx.doi.org/10.1074/ jbc.M513518200
- (2006) J. Biol. Chem. , vol.281 , pp. 12858-12864
- Ferrer, T.¹ Rupp, J.² Piper, D.R.³ Tristani-Firouzi, M.⁴

13
- 77956012263
- Calcium-activated K(+) channel (K(Ca)3. 1) activity during Ca(2+) store depletion and store-operated Ca(2+) entry in human macrophages.
- Gao, Y.D., P.J. Hanley, S. Rinné, M. Zuzarte, and J. Daut. 2010. Calcium-activated K(+) channel (K(Ca)3.1) activity during Ca(2+) store depletion and store-operated Ca(2+) entry in human macrophages. Cell Calcium. 48:19-27. http://dx.doi.org/10.1016/ j.ceca.2010.06.002
- (2010) Cell Calcium. , vol.48 , pp. 19-27
- Gao, Y.D.¹ Hanley, P.J.² Rinné, S.³ Zuzarte, M.⁴ Daut, J.⁵

14
- 58649122698
- 2+
- 2+. J. Biol. Chem. 284:389-403. http://dx.doi.org/10.1074/jbc.M805700200
- (2009) J. Biol. Chem. , vol.284 , pp. 389-403
- Garneau, L.¹ Klein, H.² Banderali, U.³ Longpré-Lauzon, A.⁴ Parent, L.⁵ Sauvé, R.⁶

15
- 77954635392
- Conformational changes during the gating of a potassium channel revealed by structural mass spectrometry
- Gupta, S., V.N. Bavro, R. D'Mello, S.J. Tucker, C. Vénien-Bryan, and M.R. Chance. 2010. Conformational changes during the gating of a potassium channel revealed by structural mass spectrometry. Structure. 18:839-846. http://dx.doi.org/10.1016/j.str.2010.04.012
- (2010) Structure. , vol.18 , pp. 839-846
- Gupta, S.¹ Bavro, V.N.² D'Mello, R.³ Tucker, S.J.⁴ Vénien-Bryan, C.⁵ Chance, M.R.⁶

16
- 84863912327
- + channel is important for secretion in pancreatic duct cells
- + channel is important for secretion in pancreatic duct cells. Am. J. Physiol. Cell Physiol. 303:C151-C159. http://dx.doi.org/10.1152/ajpcell.00089.2012
- (2012) Am. J. Physiol. Cell Physiol. , vol.303
- Hayashi, M.¹ Wang, J.² Hede, S.E.³ Novak, I.⁴

17
- 0031925086
- + channels by calcium
- + channels by calcium. J. Gen. Physiol. 111:565-581. http://dx.doi.org/10 .1085/jgp.111.4.565
- (1998) J. Gen. Physiol. , vol.111 , pp. 565-581
- Hirschberg, B.¹ Maylie, J.² Adelman, J.P.³ Marrion, N.V.⁴

18
- 0030322783
- Double-mutant cycles: a powerful tool for analyzing protein structure and function
- Horovitz, A. 1996. Double-mutant cycles: a powerful tool for analyzing protein structure and function. Fold. Des. 1:R121-R126. http://dx.doi.org/10.1016/S1359-0278(96)00056-9
- (1996) Fold. Des. , vol.1
- Horovitz, A.¹

19
- 69649091600
- + channels by 4-(2-methoxyphenylcarbamoyloxymethyl)- piperidine-1-carboxylic acid tert-butyl ester (GW542573X) is dependent on serine 293 in the S5 segment
- + channels by 4-(2-methoxyphenylcarbamoyloxymethyl)- piperidine-1-carboxylic acid tert-butyl ester (GW542573X) is dependent on serine 293 in the S5 segment. Mol. Pharmacol. 76:569-578. http://dx.doi.org/10.1124/mol.109.056663
- (2009) Mol. Pharmacol. , vol.76 , pp. 569-578
- Hougaard, C.¹ Jensen, M.L.² Dale, T.J.³ Miller, D.D.⁴ Davies, D.J.⁵ Eriksen, B.L.⁶ Strøbaek, D.⁷ Trezise, D.J.⁸ Christophersen, P.⁹

20
- 84856068484
- Evidence for a common pharmacological interaction site on K(Ca)2 channels providing both selective activation and selective inhibition of the human K(Ca)2.1
- Hougaard, C., S. Hammami, B.L. Eriksen, U.S. Sørensen, M.L. Jensen, D. StrøbÆk, and P. Christophersen. 2012. Evidence for a common pharmacological interaction site on K(Ca)2 channels providing both selective activation and selective inhibition of the human K(Ca)2.1 subtype. Mol. Pharmacol. 81:210-219. http://dx.doi.org/10.1124/ mol.111.074252
- (2012) subtype. Mol. Pharmacol. , vol.81 , pp. 210-219
- Hougaard, C.¹ Hammami, S.² Eriksen, B.L.³ Sørensen, U.S.⁴ Jensen, M.L.⁵ Strøbæk, D.⁶ Christophersen, P.⁷

21
- 79956327044
- Negative gating modulation by (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1- naphthylamine (NS8593) depends on residues in the inner pore vestibule: pharmacological evidence of deep-pore gating of K(Ca)2 channels
- Jenkins, D.P., D. StrøbÆk, C. Hougaard, M.L. Jensen, R. Hummel, U.S. Sørensen, P. Christophersen, and H. Wulff. 2011. Negative gating modulation by (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1- naphthylamine (NS8593) depends on residues in the inner pore vestibule: pharmacological evidence of deep-pore gating of K(Ca)2 channels. Mol. Pharmacol. 79:899-909. http://dx.doi.org/10.1124/ mol.110.069807
- (2011) Mol. Pharmacol. , vol.79 , pp. 899-909
- Jenkins, D.P.¹ Strøbæk, D.² Hougaard, C.³ Jensen, M.L.⁴ Hummel, R.⁵ Sørensen, U.S.⁶ Christophersen, P.⁷ Wulff, H.⁸

22
- 47149096704
- CHARMM-GUI: a webbased graphical user interface for CHARMM
- Jo, S., T. Kim, V.G. Iyer, and W. Im. 2008. CHARMM-GUI: a webbased graphical user interface for CHARMM. J. Comput. Chem. 29:1859-1865. http://dx.doi.org/10.1002/jcc.20945
- (2008) J. Comput. Chem. , vol.29 , pp. 1859-1865
- Jo, S.¹ Kim, T.² Iyer, V.G.³ Im, W.⁴

23
- 0035851178
- + channels
- + channels. J. Biol. Chem. 276:37980-37985.
- (2001) J. Biol. Chem. , vol.276 , pp. 37980-37985
- Joiner, W.J.¹ Khanna, R.² Schlichter, L.C.³ Kaczmarek, L.K.⁴

24
- 67849103757
- SAM-T08, HMM-based protein structure prediction
- Karplus, K. 2009. SAM-T08, HMM-based protein structure prediction. Nucleic Acids Res. 37:W492-W497. http://dx.doi.org/10.1093/nar/ gkp403
- (2009) Nucleic Acids Res. , vol.37
- Karplus, K.¹

25
- 33947714200
- Structural determinants of the closed KCa3.1 channel pore in relation to channel gating: Results from a substituted cysteine accessibility analysis
- Klein, H., L. Garneau, U. Banderali, M. Simoes, L. Parent, and R. Sauvé. 2007. Structural determinants of the closed KCa3.1 channel pore in relation to channel gating: Results from a substituted cysteine accessibility analysis. J. Gen. Physiol. 129:299-315. http:// dx.doi.org/10.1085/jgp.200609726
- (2007) J. Gen. Physiol. , vol.129 , pp. 299-315
- Klein, H.¹ Garneau, L.² Banderali, U.³ Simoes, M.⁴ Parent, L.⁵ Sauvé, R.⁶

26
- 60949109291
- Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells
- Klein, H., L. Garneau, N.T. Trinh, A. Privé, F. Dionne, E. Goupil, D. Thuringer, L. Parent, E. Brochiero, and R. Sauvé. 2009. Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells. Am. J. Physiol. Cell Physiol. 296:C285-C295. http://dx.doi.org/10.1152/ajpcell.00418.2008
- (2009) Am. J. Physiol. Cell Physiol. , vol.296
- Klein, H.¹ Garneau, L.² Trinh, N.T.³ Privé, A.⁴ Dionne, F.⁵ Goupil, E.⁶ Thuringer, D.⁷ Parent, L.⁸ Brochiero, E.⁹ Sauvé, R.¹⁰

27
- 78650959213
- The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure
- Labro, A.J., I.R. Boulet, F.S. Choveau, E. Mayeur, T. Bruyns, G. Loussouarn, A.L. Raes, and D.J. Snyders. 2011. The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure. J. Biol. Chem. 286:717-725. http:// dx.doi.org/10.1074/jbc.M110.146977
- (2011) J. Biol. Chem. , vol.286 , pp. 717-725
- Labro, A.J.¹ Boulet, I.R.² Choveau, F.S.³ Mayeur, E.⁴ Bruyns, T.⁵ Loussouarn, G.⁶ Raes, A.L.⁷ Snyders, D.J.⁸

28
- 67650388333
- Interactions of H562 in the S5 helix with T618 and S621 in the pore helix are important determinants of hERG1 potassium channel structure and function
- Lees-Miller, J.P., J.O. Subbotina, J. Guo, V. Yarov-Yarovoy, S.Y. Noskov, and H.J. Duff. 2009. Interactions of H562 in the S5 helix with T618 and S621 in the pore helix are important determinants of hERG1 potassium channel structure and function. Biophys. J. 96:3600-3610. http://dx.doi.org/10.1016/j.bpj.2009.01.028
- (2009) Biophys. J. , vol.96 , pp. 3600-3610
- Lees-Miller, J.P.¹ Subbotina, J.O.² Guo, J.³ Yarov-Yarovoy, V.⁴ Noskov, S.Y.⁵ Duff, H.J.⁶

29
- 0034520641
- Change of pore helix conformational state upon opening of cyclic nucleotide-gated channels
- Liu, J., and S.A. Siegelbaum. 2000. Change of pore helix conformational state upon opening of cyclic nucleotide-gated channels. Neuron. 28:899-909. http://dx.doi.org/10.1016/S0896-6273(00)00162-8
- (2000) Neuron. , vol.28 , pp. 899-909
- Liu, J.¹ Siegelbaum, S.A.²

30
- 23244456428
- + channel
- + channel. Science. 309:897-903. http://dx.doi.org/10.1126/science.1116269
- (2005) Science. , vol.309 , pp. 897-903
- Long, S.B.¹ Campbell, E.B.² Mackinnon, R.³

31
- 23244441222
- Voltage sensor of Kv1.2: structural basis of electromechanical coupling
- Long, S.B., E.B. Campbell, and R. Mackinnon. 2005b. Voltage sensor of Kv1.2: structural basis of electromechanical coupling. Science. 309:903-908. http://dx.doi.org/10.1126/science.1116270
- (2005) Science. , vol.309 , pp. 903-908
- Long, S.B.¹ Campbell, E.B.² Mackinnon, R.³

32
- 0036846783
- + channels
- + channels. J. Gen. Physiol. 120:663-676. http://dx.doi.org/10.1085/jgp.20028696
- (2002) J. Gen. Physiol. , vol.120 , pp. 663-676
- Lu, Z.¹ Klem, A.M.² Ramu, Y.³

33
- 0842279861
- + channels and calmodulin
- + channels and calmodulin. J. Physiol. 554:255-261. http://dx.doi.org/10.1113/jphysiol.2003 .049072
- (2004) J. Physiol. , vol.554 , pp. 255-261
- Maylie, J.¹ Bond, C.T.² Herson, P.S.³ Lee, W.S.⁴ Adelman, J.P.⁵

34
- 84880033656
- Contribution of the KCa3
- Morales, P., L. Garneau, H. Klein, M.F. Lavoie, L. Parent, and R. Sauvé. 2013. Contribution of the KCa3.1 channel-calmodulin interactions to the regulation of the KCa3.1 gating process. J. Gen. Physiol. 142:37-60. http://dx.doi.org/10.1085/jgp.201210933
- (2013) 1 channel-calmodulin interactions to the regulation of the KCa3.1 gating process. J. Gen. Physiol. , vol.142 , pp. 37-60
- Morales, P.¹ Garneau, L.² Klein, H.³ Lavoie, M.F.⁴ Parent, L.⁵ Sauvé, R.⁶

35
- 20444409680
- 4-Chlorobenzo[F]isoquinoline (CBIQ), a novel activator of CFTR and DeltaF508 CFTR
- Murthy, M., N. Pedemonte, L. MacVinish, L. Galietta, and A. Cuthbert. 2005. 4-Chlorobenzo[F]isoquinoline (CBIQ), a novel activator of CFTR and DeltaF508 CFTR. Eur. J. Pharmacol. 516: 118-124. http://dx.doi.org/10.1016/j.ejphar.2005.04.037
- (2005) Eur. J. Pharmacol. , vol.516 , pp. 118-124
- Murthy, M.¹ Pedemonte, N.² MacVinish, L.³ Galietta, L.⁴ Cuthbert, A.⁵

36
- 0034774587
- Mutations within the P-loop of Kir6
- Proks, P., C.E. Capener, P. Jones, and F.M. Ashcroft. 2001. Mutations within the P-loop of Kir6.2 modulate the intraburst kinetics of the ATP-sensitive potassium channel. J. Gen. Physiol. 118:341-353. http://dx.doi.org/10.1085/jgp.118.4.341
- (2001) 2 modulate the intraburst kinetics of the ATP-sensitive potassium channel. J. Gen. Physiol. , vol.118 , pp. 341-353
- Proks, P.¹ Capener, C.E.² Jones, P.³ Ashcroft, F.M.⁴

37
- 33748125213
- Reversal of HCN channel voltage dependence via bridging of the S4-S5 linker and Post-S6
- Prole, D.L., and G. Yellen. 2006. Reversal of HCN channel voltage dependence via bridging of the S4-S5 linker and Post-S6. J. Gen. Physiol. 128:273-282. http://dx.doi.org/10.1085/jgp.200609590
- (2006) J. Gen. Physiol. , vol.128 , pp. 273-282
- Prole, D.L.¹ Yellen, G.²

38
- 0030061670
- Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events
- Qin, F., A. Auerbach, and F. Sachs. 1996. Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events. Biophys. J. 70:264-280. http://dx.doi.org/10.1016/ S0006-3495(96)79568-1
- (1996) Biophys. J. , vol.70 , pp. 264-280
- Qin, F.¹ Auerbach, A.² Sachs, F.³

39
- 0030956174
- Maximum likelihood estimation of aggregated Markov processes
- Qin, F., A. Auerbach, and F. Sachs. 1997. Maximum likelihood estimation of aggregated Markov processes. Proc. Biol. Sci. 264:375- 383. http://dx.doi.org/10.1098/rspb.1997.0054
- (1997) Proc. Biol. Sci. , vol.264
- Qin, F.¹ Auerbach, A.² Sachs, F.³

40
- 33749524201
- New roles for a key glycine and its neighboring residue in potassium channel gating
- Rosenhouse-Dantsker, A., and D.E. Logothetis. 2006. New roles for a key glycine and its neighboring residue in potassium channel gating. Biophys. J. 91:2860-2873. http://dx.doi.org/10.1529/ biophysj.105.080242
- (2006) Biophys. J. , vol.91 , pp. 2860-2873
- Rosenhouse-Dantsker, A.¹ Logothetis, D.E.²

41
- 80052328287
- + channel opener 1-EBIO potentiates residual function of mutant CFTR in rectal biopsies from cystic fibrosis patients
- + channel opener 1-EBIO potentiates residual function of mutant CFTR in rectal biopsies from cystic fibrosis patients. PLoS ONE. 6:e24445. http:// dx.doi.org/10.1371/journal.pone.0024445
- (2011) PLoS ONE. , vol.6
- Roth, E.K.¹ Hirtz, S.² Duerr, J.³ Wenning, D.⁴ Eichler, I.⁵ Seydewitz, H.H.⁶ Amaral, M.D.⁷ Mall, M.A.⁸

42
- 77954065271
- I-TASSER: a unified platform for automated protein structure and function prediction
- Roy, A., A. Kucukural, and Y. Zhang. 2010. I-TASSER: a unified platform for automated protein structure and function prediction. Nat. Protoc. 5:725-738. http://dx.doi.org/10.1038/nprot.2010.5
- (2010) Nat. Protoc. , vol.5 , pp. 725-738
- Roy, A.¹ Kucukural, A.² Zhang, Y.³

43
- 0027136282
- Comparative protein modelling by satisfaction of spatial restraints
- Šali, A., and T.L. Blundell. 1993. Comparative protein modelling by satisfaction of spatial restraints. J. Mol. Biol. 234:779-815. http:// dx.doi.org/10.1006/jmbi.1993.1626
- (1993) J. Mol. Biol. , vol.234 , pp. 779-815
- Šali, A.¹ Blundell, T.L.²

44
- 0033179780
- Packing of aromatic rings against tryptophan residues in proteins
- Samanta, U., D. Pal, and P. Chakrabarti. 1999. Packing of aromatic rings against tryptophan residues in proteins. Acta Crystallogr. D Biol. Crystallogr. 55:1421-1427. http://dx.doi.org/10.1107/ S090744499900726X
- (1999) Acta Crystallogr. D Biol. Crystallogr. , vol.55 , pp. 1421-1427
- Samanta, U.¹ Pal, D.² Chakrabarti, P.³

45
- 0035953757
- 2+/calmodulin
- 2+/calmodulin. Nature. 410:1120-1124. http:// dx.doi.org/10.1038/35074145
- (2001) Nature. , vol.410 , pp. 1120-1124
- Schumacher, M.A.¹ Rivard, A.F.² Bächinger, H.P.³ Adelman, J.P.⁴

46
- 2342513320
- Crystal structures of apocalmodulin and an apocalmodulin/SK potassium channel gating domain complex
- Schumacher, M.A., M. Crum, and M.C. Miller. 2004. Crystal structures of apocalmodulin and an apocalmodulin/SK potassium channel gating domain complex. Structure. 12:849-860. http:// dx.doi.org/10.1016/j.str.2004.03.017
- (2004) Structure. , vol.12 , pp. 849-860
- Schumacher, M.A.¹ Crum, M.² Miller, M.C.³

47
- 14944352048
- + channels
- + channels. J. Physiol. 563:359-368. http:// dx.doi.org/10.1113/jphysiol.2004.080887
- (2005) J. Physiol. , vol.563 , pp. 359-368
- Seebohm, G.¹ Westenskow, P.² Lang, F.³ Sanguinetti, M.C.⁴

48
- 65349108635
- Openers of SKCa and IKCa channels enhance agonist-evoked endothelial nitric oxide synthesis and arteriolar vasodilation
- Sheng, J.Z., S. Ella, M.J. Davis, M.A. Hill, and A.P. Braun. 2009. Openers of SKCa and IKCa channels enhance agonist-evoked endothelial nitric oxide synthesis and arteriolar vasodilation. FASEB J. 23:1138-1145. http://dx.doi.org/10.1096/fj.08-120451
- (2009) FASEB J. , vol.23 , pp. 1138-1145
- Sheng, J.Z.¹ Ella, S.² Davis, M.J.³ Hill, M.A.⁴ Braun, A.P.⁵

49
- 0036020150
- Cysteine mutagenesis and computer modeling of the S6 region of an intermediate conductance IKCa channel
- Simoes, M., L. Garneau, H. Klein, U. Banderali, F. Hobeila, B. Roux, L. Parent, and R. Sauvé. 2002. Cysteine mutagenesis and computer modeling of the S6 region of an intermediate conductance IKCa channel. J. Gen. Physiol. 120:99-116. http://dx.doi .org/10.1085/jgp.20028586
- (2002) J. Gen. Physiol. , vol.120 , pp. 99-116
- Simoes, M.¹ Garneau, L.² Klein, H.³ Banderali, U.⁴ Hobeila, F.⁵ Roux, B.⁶ Parent, L.⁷ Sauvé, R.⁸

50
- 0035146762
- Benzimidazolone activators of chloride secretion: potential therapeutics for cystic fibrosis and chronic obstructive pulmonary disease
- Singh, S., C.A. Syme, A.K. Singh, D.C. Devor, and R.J. Bridges. 2001. Benzimidazolone activators of chloride secretion: potential therapeutics for cystic fibrosis and chronic obstructive pulmonary disease. J. Pharmacol. Exp. Ther. 296:600-611.
- (2001) J. Pharmacol. Exp. Ther. , vol.296 , pp. 600-611
- Singh, S.¹ Syme, C.A.² Singh, A.K.³ Devor, D.C.⁴ Bridges, R.J.⁵

51
- 3042700158
- 4-Chloro-benzo[F]isoquinoline (CBIQ) activates CFTR chloride channels and KCNN4 potassium channels in Calu-3 human airway epithelial cells
- Szkotak, A.J., M. Murthy, L.J. MacVinish, M. Duszyk, and A.W. Cuthbert. 2004. 4-Chloro-benzo[F]isoquinoline (CBIQ) activates CFTR chloride channels and KCNN4 potassium channels in Calu-3 human airway epithelial cells. Br. J. Pharmacol. 142:531- 542. http://dx.doi.org/10.1038/sj.bjp.0705846
- (2004) Br. J. Pharmacol. , vol.142
- Szkotak, A.J.¹ Murthy, M.² MacVinish, L.J.³ Duszyk, M.⁴ Cuthbert, A.W.⁵

52
- 79961017278
- Double mutant cycle analysis identified a critical leucine residue in the IIS4S5 linker for the activation of the Ca(V)2.3 calcium channel
- Wall-Lacelle, S., M.I. Hossain, R. Sauvé, R. Blunck, and L. Parent. 2011. Double mutant cycle analysis identified a critical leucine residue in the IIS4S5 linker for the activation of the Ca(V)2.3 calcium channel. J. Biol. Chem. 286:27197-27205. http://dx.doi .org/10.1074/jbc.M111.237412
- (2011) J. Biol. Chem. , vol.286 , pp. 27197-27205
- Wall-Lacelle, S.¹ Hossain, M.I.² Sauvé, R.³ Blunck, R.⁴ Parent, L.⁵

53
- 33745946445
- A genetically encoded fluorescent amino acid
- Wang, J., J. Xie, and P.G. Schultz. 2006. A genetically encoded fluorescent amino acid. J. Am. Chem. Soc. 128:8738-8739. http:// dx.doi.org/10.1021/ja062666k
- (2006) J. Am. Chem. Soc. , vol.128 , pp. 8738-8739
- Wang, J.¹ Xie, J.² Schultz, P.G.³

54
- 0030005250
- Solvation energies of amino acid side chains and backbone in a family of hostguest pentapeptides
- Wimley, W.C., T.P. Creamer, and S.H. White. 1996. Solvation energies of amino acid side chains and backbone in a family of hostguest pentapeptides. Biochemistry. 35:5109-5124. http://dx.doi .org/10.1021/bi9600153
- (1996) Biochemistry. , vol.35 , pp. 5109-5124
- Wimley, W.C.¹ Creamer, T.P.² White, S.H.³

55
- 18544371853
- + channels controls assembly with apo-calmodulin
- + channels controls assembly with apo-calmodulin. J. Biol. Chem. 277:4558-4564. http://dx.doi.org/10.1074/jbc.M109240200
- (2002) J. Biol. Chem. , vol.277 , pp. 4558-4564
- Wissmann, R.¹ Bildl, W.² Neumann, H.³ Rivard, A.F.⁴ Klöcker, N.⁵ Weitz, D.⁶ Schulte, U.⁷ Adelman, J.P.⁸ Bentrop, D.⁹ Fakler, B.¹⁰

56
- 0034608869
- + channel, IKCa1: a potential immunosuppressant
- USA.
- + channel, IKCa1: a potential immunosuppressant. Proc. Natl. Acad. Sci. USA. 97:8151-8156. http://dx.doi.org/10.1073/pnas.97.14.8151
- (2000) Proc. Natl. Acad. Sci. , vol.97 , pp. 8151-8156
- Wulff, H.¹ Miller, M.J.² Hansel, W.³ Grissmer, S.⁴ Cahalan, M.D.⁵ Chandy, K.G.⁶

57
- 3142775617
- + channel expression during B cell differentiation: implications for immunomodulation and autoimmunity
- + channel expression during B cell differentiation: implications for immunomodulation and autoimmunity. J. Immunol. 173:776-786.
- (2004) J. Immunol. , vol.173 , pp. 776-786
- Wulff, H.¹ Knaus, H.G.² Pennington, M.³ Chandy, K.G.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.