4-Chloro-benzo[F]isoquinoline (CBIQ) activates CFTR chloride channels and KCNN4 potassium channels in Calu-3 human airway epithelial cells

British Journal of Pharmacology

Volumn 142, Issue 3, 2004, Pages 531-542

  Szkotak, A J ^a   Murthy, M ^b   MacVinish, L J ^b   Duszyk, M ^a   Cuthbert, A W ^b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

4 Chloro benzo F isoquinoline; 5,6 benzoquinoline; 7,8 benzoquinoline; Calcium sensitive potassium channels; CFTR activators; Cystic fibrosis; Cystic fibrosis transmembrane conductance regulator (CFTR)

Indexed keywords

4 CHLOROBENZ[F]ISOQUINOLINE; ADENOSINE TRIPHOSPHATE; CHLORINE 36; CLOTRIMAZOLE; GLIBENCLAMIDE; GUANOSINE TRIPHOSPHATE; ISOQUINOLINE DERIVATIVE; NUCLEOTIDE; POTASSIUM CHANNEL; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG;

APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL PERMEABILIZATION; CELL STRAIN; CONDUCTANCE; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; MONOLAYER CULTURE; PATCH CLAMP; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; SHORT CIRCUIT CURRENT;

CELL LINE; CHLORIDES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL CELLS; HUMANS; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; ION CHANNEL GATING; ISOQUINOLINES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; RESPIRATORY MUCOSA;

EID: 3042700158     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705846     Document Type: Article

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