Openers of SKCa and IKCa channels enhance agonist-evoked endothelial nitric oxide synthesis and arteriolar vasodilation

FASEB Journal

Volumn 23, Issue 4, 2009, Pages 1138-1145

  Sheng, Jian Zhong ^a   Ella, Srikanth ^b   Davis, Michael J ^b   Hill, Michael A ^b   Braun, Andrew P ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

Ca 2+ activated; Calcium; Hyperpolarization; Myogenic tone; Relaxation; Resistance artery

Indexed keywords

3 OXIME 6,7 DICHLORO 1H INDOLE 2,3 DIONE; 5,6 DICHLORO 1 ETHYL 1,3 DIHYDRO 2H BENZIMIDAZOLE 2 ONE; ACETYLCHOLINE; ADENOSINE TRIPHOSPHATE; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NS 309; POTASSIUM CHANNEL STIMULATING AGENT; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; UNCLASSIFIED DRUG; 3 AMINO 4 MONOMETHYLAMINO 2',7' DIFLUOROFLUORECEIN; 3-AMINO-4-MONOMETHYLAMINO-2',7'-DIFLUOROFLUORECEIN; 5,6 DICHLORO 1 ETHYL 1,3 DIHYDRO 2H BENZIMIDAZOL 2 ONE; 5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE; 6,7 DICHLORO 1H INDOLE 2,3 DIONE 3 OXIME; 6,7-DICHLORO-1H-INDOLE-2,3-DIONE 3-OXIME; BENZIMIDAZOLE DERIVATIVE; CALCIUM; CALCIUM ACTIVATED POTASSIUM CHANNEL; ETHYLAMINE; FLUORESCEIN DERIVATIVE; INDOLE DERIVATIVE; OXIME;

ANIMAL TISSUE; ARTERIOLE; ARTICLE; CARDIOVASCULAR DISEASE; CELL ISOLATION; CREMASTER MUSCLE; CYTOSOL; DRUG EFFECT; ENDOTHELIUM CELL; EVOKED RESPONSE; HUMAN; HUMAN CELL; HYPERPOLARIZATION; IC 50; MEMBRANE POTENTIAL; MICROFLUOROMETRY; MICROSCOPY; MUSCLE TONE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SYNTHESIS; VASODILATATION; VIDEORECORDING; ANIMAL; BIOSYNTHESIS; CELL LINE; CELL MEMBRANE POTENTIAL; DOSE RESPONSE; DRUG POTENTIATION; FLUOROMETRY; MALE; METABOLISM; PHYSIOLOGY;

RATTUS;

ACETYLCHOLINE; ADENOSINE TRIPHOSPHATE; ANIMALS; ARTERIOLES; BENZIMIDAZOLES; CALCIUM; CELL LINE; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ETHYLAMINES; FLUORESCEINS; FLUOROMETRY; HUMANS; INDOLES; INHIBITORY CONCENTRATION 50; MALE; MEMBRANE POTENTIALS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; OXIMES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; RATS; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; VASODILATION;

EID: 65349108635     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.08-120451     Document Type: Article

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