메뉴 건너뛰기




Volumn 52, Issue 1-2, 2005, Pages 1-9

Involvement of cathepsins in the invasion, metastasis and proliferation of cancer cells

Author keywords

Cancer; Cathepsins; Inhibitors; Invasion; Metastasis

Indexed keywords

BIOLOGICAL MARKER; CATHEPSIN; CATHEPSIN B; CATHEPSIN D; CATHEPSIN L; CHEMOKINE; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; CHEMOKINE RECEPTOR CXCR3; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR5; EOTAXIN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 6; LYSOSOME ENZYME; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 4; PROTEIN INHIBITOR; PROTEINASE; RANTES; STROMAL CELL DERIVED FACTOR 1; UNINDEXED DRUG; COMPLEMENTARY DNA; CYSTEINE PROTEINASE INHIBITOR;

EID: 15544384612     PISSN: 13431420     EISSN: None     Source Type: Journal    
DOI: 10.2152/jmi.52.1     Document Type: Review
Times cited : (204)

References (63)
  • 1
    • 0022555838 scopus 로고
    • Biochemical interactions of tumor cells with the basement membrane
    • Liotta LA, Rao CN, Wewer UM: Biochemical interactions of tumor cells with the basement membrane. Annu Rev Biochem 55: 1037-1035, 1986
    • (1986) Annu Rev Biochem , vol.55 , pp. 1037-1035
    • Liotta, L.A.1    Rao, C.N.2    Wewer, U.M.3
  • 3
    • 0031685364 scopus 로고    scopus 로고
    • Cysteine proteinases and their endogenous inhibitors: Target proteins for prognosis, diagnosis and therapy in cancer
    • Kos J, Lah TT: Cysteine proteinases and their endogenous inhibitors: target proteins for prognosis, diagnosis and therapy in cancer (review). Oncol Rep 5: 1349-1346, 1998
    • (1998) Oncol Rep , vol.5 , pp. 1349-1346
    • Kos, J.1    Lah, T.T.2
  • 5
    • 0343340434 scopus 로고    scopus 로고
    • Cathepsin B, a prognostic indicator in lymph node-negative breast carcinoma patients: Comparison with cathepsin D, cathepsin L, and other clinical indicators
    • Lah TT, Cercek M, Blejec A, Kos J, Gorodetsky E, Somers R, Daskal I: Cathepsin B, a prognostic indicator in lymph node-negative breast carcinoma patients: comparison with cathepsin D, cathepsin L, and other clinical indicators. Clin Cancer Res 6: 578-584, 2000
    • (2000) Clin Cancer Res , vol.6 , pp. 578-584
    • Lah, T.T.1    Cercek, M.2    Blejec, A.3    Kos, J.4    Gorodetsky, E.5    Somers, R.6    Daskal, I.7
  • 7
    • 0040679257 scopus 로고
    • Identification and characterization of cells deficient in the mannose 6-phosphate receptor: Evidence for an alternate pathway for lysosomal enzyme targeting
    • Gabel CA, Goldberg DE, Kornfeld S: Identification and characterization of cells deficient in the mannose 6-phosphate receptor: evidence for an alternate pathway for lysosomal enzyme targeting. Proc Natl Acad Sci USA 80: 775-779, 1983
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 775-779
    • Gabel, C.A.1    Goldberg, D.E.2    Kornfeld, S.3
  • 8
    • 0026779307 scopus 로고
    • Cathepsin D in breast cancer: A tissue marker associated with metastasis
    • Rochefort H: Cathepsin D in breast cancer: a tissue marker associated with metastasis. Eur J Cancer 28A: 1780-1783, 1992
    • (1992) Eur J Cancer , vol.28 A , pp. 1780-1783
    • Rochefort, H.1
  • 9
    • 0030748777 scopus 로고    scopus 로고
    • Relationship between cathepsin-D content and disease-free survival in node-negative breast cancer patients: A meta-analysis
    • Ferrandina G, Scambia G, Bardelli F, Benedetti Panici P, Mancuso S, Messori A: Relationship between cathepsin-D content and disease-free survival in node-negative breast cancer patients: a meta-analysis. Br J Cancer 76: 661-666, 1997
    • (1997) Br J Cancer , vol.76 , pp. 661-666
    • Ferrandina, G.1    Scambia, G.2    Bardelli, F.3    Benedetti Panici, P.4    Mancuso, S.5    Messori, A.6
  • 10
    • 0032324792 scopus 로고    scopus 로고
    • Analysis of cathepsin D forms and their clinical implications in human prostate cancer
    • Cherry JP, Mordente JA, Chapman JR, Choudhury MS, Tazaki H, Mallouh C, Konno S: Analysis of cathepsin D forms and their clinical implications in human prostate cancer. J Urol 160 (6 Pt 1): 2223-2228, 1998
    • (1998) J Urol , vol.160 , Issue.6 PART 1 , pp. 2223-2228
    • Cherry, J.P.1    Mordente, J.A.2    Chapman, J.R.3    Choudhury, M.S.4    Tazaki, H.5    Mallouh, C.6    Konno, S.7
  • 12
    • 0027475947 scopus 로고
    • Cathepsin D gene is controlled by a mixed promoter, and estrogens stimulate only TATA-dependent transcription in breast cancer cells
    • Cavailles V, Augereau P, Rochefort H: Cathepsin D gene is controlled by a mixed promoter, and estrogens stimulate only TATA-dependent transcription in breast cancer cells. Proc Natl Acad Sci USA 90: 203-207, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 203-207
    • Cavailles, V.1    Augereau, P.2    Rochefort, H.3
  • 14
    • 0023610145 scopus 로고
    • Cysteine proteinase cathepsin L expression correlates closely with the metastatic potential of H-ras-transformed murine fibroblasts
    • Denhardt DT, Greenberg AH, Egan SE, Hamilton RT, Wright JA: Cysteine proteinase cathepsin L expression correlates closely with the metastatic potential of H-ras-transformed murine fibroblasts. Oncogene 2: 55-59, 1987
    • (1987) Oncogene , vol.2 , pp. 55-59
    • Denhardt, D.T.1    Greenberg, A.H.2    Egan, S.E.3    Hamilton, R.T.4    Wright, J.A.5
  • 15
    • 0024322516 scopus 로고
    • Expression of five cathepsins in murine melanomas of varying metastatic potential and normal tissues
    • Qian F, Bajkowski AS, Steiner DF, Chan SJ, Frankfeter A: Expression of five cathepsins in murine melanomas of varying metastatic potential and normal tissues. Cancer Res 49: 4870-4875, 1989
    • (1989) Cancer Res , vol.49 , pp. 4870-4875
    • Qian, F.1    Bajkowski, A.S.2    Steiner, D.F.3    Chan, S.J.4    Frankfeter, A.5
  • 16
    • 0037082140 scopus 로고    scopus 로고
    • Structure-based design of specific cathepsin inhibitors and their application to protection of bone metastases of cancer cells
    • Katunuma N, Tsuge H, Nukatsuka M, Asao T, Fukushima M: Structure-based design of specific cathepsin inhibitors and their application to protection of bone metastases of cancer cells. Arch Biochem Biophys 397: 305-311, 2002
    • (2002) Arch Biochem Biophys , vol.397 , pp. 305-311
    • Katunuma, N.1    Tsuge, H.2    Nukatsuka, M.3    Asao, T.4    Fukushima, M.5
  • 17
    • 0032785539 scopus 로고    scopus 로고
    • Anti-human procathepsin D activation peptide antibodies inhibit breast cancer development Breast
    • Vetvicka V, Vetvickova J, Fusek M: Anti-human procathepsin D activation peptide antibodies inhibit breast cancer development Breast Cancer Res Treat 57: 261-269, 1999
    • (1999) Cancer Res Treat , vol.57 , pp. 261-269
    • Vetvicka, V.1    Vetvickova, J.2    Fusek, M.3
  • 18
    • 0028028428 scopus 로고
    • Mitogenic function of human procathepsin D: The role of the propeptide
    • Fusek M and Vetvicka V: Mitogenic function of human procathepsin D: the role of the propeptide. Biochem J 303(Pt 3): 775-780, 1994
    • (1994) Biochem J , vol.303 , Issue.PART 3 , pp. 775-780
    • Fusek, M.1    Vetvicka, V.2
  • 19
    • 0036676298 scopus 로고    scopus 로고
    • Down-regulation of cathepsin-D expression by antisense gene transfer inhibits tumor growth and experimental lung metastasis of human breast cancer cells
    • Glondu M, Liaudet-Coopman E, Derocq D, Platet N, Rochefort H, Garcia M: Down-regulation of cathepsin-D expression by antisense gene transfer inhibits tumor growth and experimental lung metastasis of human breast cancer cells. Oncogene 21: 5127-5134, 2002
    • (2002) Oncogene , vol.21 , pp. 5127-5134
    • Glondu, M.1    Liaudet-Coopman, E.2    Derocq, D.3    Platet, N.4    Rochefort, H.5    Garcia, M.6
  • 20
  • 22
    • 0037377728 scopus 로고    scopus 로고
    • Cathepsin D specifically cleaves the chemokines macrophage inflammatory protein-1 alpha, macrophage inflammatory protein-1 beta, and SLC that are expressed in human breast cancer
    • Wolf M, Clark-Lewis I, Buri C, Langen H, Lis M, Mazzucchelli L: Cathepsin D specifically cleaves the chemokines macrophage inflammatory protein-1 alpha, macrophage inflammatory protein-1 beta, and SLC that are expressed in human breast cancer. Am J Pathol 162: 1183-1190, 2003
    • (2003) Am J Pathol , vol.162 , pp. 1183-1190
    • Wolf, M.1    Clark-Lewis, I.2    Buri, C.3    Langen, H.4    Lis, M.5    Mazzucchelli, L.6
  • 23
    • 0025771650 scopus 로고
    • Are cancer cells acidic?
    • Griffiths JR: Are cancer cells acidic? Br J Cancer 64: 425-427, 1991
    • (1991) Br J Cancer , vol.64 , pp. 425-427
    • Griffiths, J.R.1
  • 24
    • 0030754527 scopus 로고    scopus 로고
    • Breast cancer cells have a high capacity to acidify extracellular milieu by a dual mechanism
    • Montcourrier P, Silver I, Farnoud R, Bird I, Rochefort H: Breast cancer cells have a high capacity to acidify extracellular milieu by a dual mechanism. Clin Exp Metastasis 15: 382-392, 1997
    • (1997) Clin Exp Metastasis , vol.15 , pp. 382-392
    • Montcourrier, P.1    Silver, I.2    Farnoud, R.3    Bird, I.4    Rochefort, H.5
  • 25
    • 0034687547 scopus 로고    scopus 로고
    • Overexpression of vacuolar ATPase 16-kDa subunit in 10T1/2 fibroblasts enhances invasion with concomitant induction of matrix metalloproteinase-2
    • Kubota S, Seyama Y: Overexpression of vacuolar ATPase 16-kDa subunit in 10T1/2 fibroblasts enhances invasion with concomitant induction of matrix metalloproteinase-2. Biochem Biophys Res Commun 278: 390-394, 2000
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 390-394
    • Kubota, S.1    Seyama, Y.2
  • 27
    • 0142166426 scopus 로고    scopus 로고
    • Chemokines: Agents for the immunotherapy of cancer?
    • Homey B, Muller A, Zlotnik A: Chemokines: agents for the immunotherapy of cancer? Nat Rev Immunol 2: 175-184, 2002
    • (2002) Nat Rev Immunol , vol.2 , pp. 175-184
    • Homey, B.1    Muller, A.2    Zlotnik, A.3
  • 30
    • 0036153123 scopus 로고    scopus 로고
    • Tumour escape from immune surveillance through dendritic cell inactivation
    • Vicari AP, Caux C, Trinchieri G: Tumour escape from immune surveillance through dendritic cell inactivation. Semin Cancer Biol 12: 33-42, 2002
    • (2002) Semin Cancer Biol , vol.12 , pp. 33-42
    • Vicari, A.P.1    Caux, C.2    Trinchieri, G.3
  • 31
  • 32
    • 0035447414 scopus 로고    scopus 로고
    • Significant correlation of monocyte chemoattractant protein-1 expression with neovascularization and progression of breast carcinoma
    • Saji H, Koike M, Yamori T, Saji S, Seiki M, Matsushima K, Toi M: Significant correlation of monocyte chemoattractant protein-1 expression with neovascularization and progression of breast carcinoma. Cancer 92: 1085-1091, 2001
    • (2001) Cancer , vol.92 , pp. 1085-1091
    • Saji, H.1    Koike, M.2    Yamori, T.3    Saji, S.4    Seiki, M.5    Matsushima, K.6    Toi, M.7
  • 33
    • 0033903714 scopus 로고    scopus 로고
    • Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer
    • Ueno T, Toi M, Saji H, Muta M, Bando H, Kuroi K, Koike M, Inadera H, Matsushima K: Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer. Clin Cancer Res 6: 3282-3289, 2000
    • (2000) Clin Cancer Res , vol.6 , pp. 3282-3289
    • Ueno, T.1    Toi, M.2    Saji, H.3    Muta, M.4    Bando, H.5    Kuroi, K.6    Koike, M.7    Inadera, H.8    Matsushima, K.9
  • 35
    • 0942301172 scopus 로고    scopus 로고
    • Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells
    • Fernandis AZ, Prasad A, Band H, Klosel R, Ganju RK: Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells. Oncogene 23: 157-167, 2004
    • (2004) Oncogene , vol.23 , pp. 157-167
    • Fernandis, A.Z.1    Prasad, A.2    Band, H.3    Klosel, R.4    Ganju, R.K.5
  • 36
    • 0003083706 scopus 로고    scopus 로고
    • The expression of lysosomal proteinases and their inhibitors in breast cancer: Possible relationship to prognosis of the disease
    • Lah TT, Kos J, Blejec A, Frkovic-Georgio S, Golouh R, Vrhovec I, Turk V: The Expression of Lysosomal Proteinases and Their Inhibitors in Breast Cancer: Possible Relationship to Prognosis of the Disease. Pathol Oncol Res 3: 89-99, 1997
    • (1997) Pathol Oncol Res , vol.3 , pp. 89-99
    • Lah, T.T.1    Kos, J.2    Blejec, A.3    Frkovic-Georgio, S.4    Golouh, R.5    Vrhovec, I.6    Turk, V.7
  • 37
    • 0036947460 scopus 로고    scopus 로고
    • Comparison of potential biological markers cathepsin B, cathepsin L, stefin A and stefin B with urokinase and plasminogen activator inhibitor-1 and clinicopathological data of breast carcinoma patients
    • Levicar N, Kos J, Blejec A, Golouh R, Vrhovec I, Frkovic-Grazio S, Lah TT: Comparison of potential biological markers cathepsin B, cathepsin L, stefin A and stefin B with urokinase and plasminogen activator inhibitor-1 and clinicopathological data of breast carcinoma patients. Cancer Detect Prev 26: 42-49, 2002
    • (2002) Cancer Detect Prev , vol.26 , pp. 42-49
    • Levicar, N.1    Kos, J.2    Blejec, A.3    Golouh, R.4    Vrhovec, I.5    Frkovic-Grazio, S.6    Lah, T.T.7
  • 38
  • 39
    • 0034255167 scopus 로고    scopus 로고
    • Immunostained cathepsins B and L correlate with depth of invasion and different metastatic pathways in early stage gastric carcinoma
    • Dohchin A, Suzuki JI, Seki H, Masutani M, Shiroto H, Kawakami Y: Immunostained cathepsins B and L correlate with depth of invasion and different metastatic pathways in early stage gastric carcinoma. Cancer 89: 482-487, 2000
    • (2000) Cancer , vol.89 , pp. 482-487
    • Dohchin, A.1    Suzuki, J.I.2    Seki, H.3    Masutani, M.4    Shiroto, H.5    Kawakami, Y.6
  • 42
    • 0037058622 scopus 로고    scopus 로고
    • Expression of cysteine peptidase cathepsin L and its inhibitors stefins A and B in relation to tumorigenicity of breast cancer cell lines
    • Zajc I, Sever N, Bervar A, Lah TT: Expression of cysteine peptidase cathepsin L and its inhibitors stefins A and B in relation to tumorigenicity of breast cancer cell lines. Cancer Lett 187: 185-190, 2002
    • (2002) Cancer Lett , vol.187 , pp. 185-190
    • Zajc, I.1    Sever, N.2    Bervar, A.3    Lah, T.T.4
  • 43
    • 0029021787 scopus 로고
    • Tissue cathepsins as tumor markers
    • Schwartz MK: Tissue cathepsins as tumor markers. Clin Chim Acta 237: 67-78, 1995
    • (1995) Clin Chim Acta , vol.237 , pp. 67-78
    • Schwartz, M.K.1
  • 44
    • 0037191505 scopus 로고    scopus 로고
    • Increased cell density decreases cysteine proteinase inhibitor activity and increases invasive ability of two prostate tumor cell lines
    • Colella R, Goodwyn E, Gopal P: Increased cell density decreases cysteine proteinase inhibitor activity and increases invasive ability of two prostate tumor cell lines. Cancer Lett 185: 163-172, 2002
    • (2002) Cancer Lett , vol.185 , pp. 163-172
    • Colella, R.1    Goodwyn, E.2    Gopal, P.3
  • 45
    • 0037096882 scopus 로고    scopus 로고
    • Prediction of pelvic lymph node metastasis by the ratio of cathepsin B to stefin A in patients with prostate carcinoma
    • Sinha AA, Quast BJ, Wilson MJ, Fernandes ET, Reddy PK, Ewing SL, Gleason DF: Prediction of pelvic lymph node metastasis by the ratio of cathepsin B to stefin A in patients with prostate carcinoma. Cancer 94: 3141-3149, 2002
    • (2002) Cancer , vol.94 , pp. 3141-3149
    • Sinha, A.A.1    Quast, B.J.2    Wilson, M.J.3    Fernandes, E.T.4    Reddy, P.K.5    Ewing, S.L.6    Gleason, D.F.7
  • 46
    • 0041382248 scopus 로고    scopus 로고
    • Decreased activity of cathepsins L+B and decreased invasive ability of PC3 prostate cancer cells
    • Colella R, Casey SF: Decreased activity of cathepsins L+B and decreased invasive ability of PC3 prostate cancer cells. Biotech Histochem 78: 101-108, 2003
    • (2003) Biotech Histochem , vol.78 , pp. 101-108
    • Colella, R.1    Casey, S.F.2
  • 48
    • 0035870263 scopus 로고    scopus 로고
    • An intracellular form of cathepsin B contributes to invasiveness in cancer
    • Szpaderska AM, Frankfater A: An intracellular form of cathepsin B contributes to invasiveness in cancer. Cancer Res 61: 3493-3500, 2001
    • (2001) Cancer Res , vol.61 , pp. 3493-3500
    • Szpaderska, A.M.1    Frankfater, A.2
  • 49
    • 0034075042 scopus 로고    scopus 로고
    • Antisense RNA inhibition of cathepsin L expression reduces tumorigenicity of malignant cells
    • Kirschke H, Eerola R, Hopsu-Havu VK, Bromme D, Vuorio E: Antisense RNA inhibition of cathepsin L expression reduces tumorigenicity of malignant cells. Eur J Cancer 36: 787-795, 2000
    • (2000) Eur J Cancer , vol.36 , pp. 787-795
    • Kirschke, H.1    Eerola, R.2    Hopsu-Havu, V.K.3    Bromme, D.4    Vuorio, E.5
  • 54
    • 0029054807 scopus 로고
    • Structure, properties, mechanisms, and assays of cysteine protease inhibitors; cystatins and E-64 derivatives
    • Katunuma N and Kominami E: Structure, Properties, Mechanisms, and Assays of Cysteine Protease inhibitors; Cystatins and E-64 Derivatives. Methods in Enzymology 251: 382-397, 1995
    • (1995) Methods in Enzymology , vol.251 , pp. 382-397
    • Katunuma, N.1    Kominami, E.2
  • 56
    • 0032561376 scopus 로고    scopus 로고
    • Synthesis of peptide aldehyde derivatives as selective inhibitors of human cathepsin L and their inhibitory effect on bone resorption
    • Yasuma T, Oi S, Choh N, Nomura T, Furuyama N, Nishimura A, Fujisawa Y, Sohda T: Synthesis of peptide aldehyde derivatives as selective inhibitors of human cathepsin L and their inhibitory effect on bone resorption. J Med Chem 41: 4301-4308, 1998
    • (1998) J Med Chem , vol.41 , pp. 4301-4308
    • Yasuma, T.1    Oi, S.2    Choh, N.3    Nomura, T.4    Furuyama, N.5    Nishimura, A.6    Fujisawa, Y.7    Sohda, T.8
  • 58
    • 0038644575 scopus 로고    scopus 로고
    • Invasiveness of transformed human breast epithelial cell lines is related to cathepsin B and inhibited by cysteine proteinase inhibitors
    • Bervar A, Zajc I, Sever N, Katunuma N, Sloane BF, Lah TT: Invasiveness of transformed human breast epithelial cell lines is related to cathepsin B and inhibited by cysteine proteinase inhibitors. Biol Chem 384: 447-455, 2003
    • (2003) Biol Chem , vol.384 , pp. 447-455
    • Bervar, A.1    Zajc, I.2    Sever, N.3    Katunuma, N.4    Sloane, B.F.5    Lah, T.T.6
  • 61
    • 0029744988 scopus 로고    scopus 로고
    • Mechanistic studies on the inactivation of papain by epoxysuccinyl inhibitors
    • Meara JP, Rich DH: Mechanistic studies on the inactivation of papain by epoxysuccinyl inhibitors. J Med Chem 39: 3357-3366, 1996
    • (1996) J Med Chem , vol.39 , pp. 3357-3366
    • Meara, J.P.1    Rich, D.H.2
  • 62
    • 0037192458 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
    • Review
    • Coussens LM, Fingleton B, Matrisian LM: Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 295(5564): 2387-2392 (Review), 2002
    • (2002) Science , vol.295 , Issue.5564 , pp. 2387-2392
    • Coussens, L.M.1    Fingleton, B.2    Matrisian, L.M.3
  • 63
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • Perl AK, Wilgenbus P, Dahl U, Semb H, Christofori G: A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 392: 190-193, 1998
    • (1998) Nature , vol.392 , pp. 190-193
    • Perl, A.K.1    Wilgenbus, P.2    Dahl, U.3    Semb, H.4    Christofori, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.