-
1
-
-
35348877164
-
Transcriptional signatures in Huntington's disease
-
Cha, J.H. (2007) Transcriptional signatures in Huntington's disease. Prog. Neurobiol., 83, 228-248.
-
(2007)
Prog. Neurobiol.
, vol.83
, pp. 228-248
-
-
Cha, J.H.1
-
2
-
-
0030612119
-
Dopamine D1 and D2 receptor gene expression in the striatum in Huntington's disease
-
Augood, S.J., Faull, R.L. and Emson, P.C. (1997) Dopamine D1 and D2 receptor gene expression in the striatum in Huntington's disease. Ann. Neurol., 42, 215-221.
-
(1997)
Ann. Neurol.
, vol.42
, pp. 215-221
-
-
Augood, S.J.1
Faull, R.L.2
Emson, P.C.3
-
3
-
-
0032568517
-
Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene
-
Cha, J.H., Kosinski, C.M., Kerner, J.A., Alsdorf, S.A., Mangiarini, L., Davies, S.W., Penney, J.B., Bates, G.P. and Young, A.B. (1998) Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene. Proc. Natl Acad. Sci. USA, 95, 6480-6485.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 6480-6485
-
-
Cha, J.H.1
Kosinski, C.M.2
Kerner, J.A.3
Alsdorf, S.A.4
Mangiarini, L.5
Davies, S.W.6
Penney J.B.Bates, G.P.7
Young, A.B.8
-
4
-
-
0034702030
-
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease
-
Luthi-Carter, R., Strand, A., Peters, N.L., Solano, S.M., Hollingsworth, Z.R., Menon, A.S., Frey, A.S., Spektor, B.S., Penney, E.B., Schilling, G. et al. (2000) Decreased expression of striatal signaling genes in a mouse model of Huntington's disease. Hum. Mol. Genet., 9, 1259-1271.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 1259-1271
-
-
Luthi-Carter, R.1
Strand, A.2
Peters, N.L.3
Solano, S.M.4
Hollingsworth, Z.R.5
Menon, A.S.6
Frey, A.S.7
Spektor, B.S.8
Penney, E.B.9
Schilling, G.10
-
5
-
-
34447317536
-
Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models
-
Sadri-Vakili, G., Bouzou, B., Benn, C.L., Kim, M.O., Chawla, P., Overland, R.P., Glajch, K.E., Xia, E., Qiu, Z., Hersch, S.M. et al. (2007) Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models. Hum. Mol. Genet., 16, 1293-1306.
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 1293-1306
-
-
Sadri-Vakili, G.1
Bouzou, B.2
Benn, C.L.3
Kim, M.O.4
Chawla, P.5
Overland, R.P.6
Glajch, K.E.7
Xia, E.8
Qiu, Z.9
Hersch, S.M.10
-
6
-
-
34547839797
-
Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage
-
Kuhn, A., Goldstein, D.R., Hodges, A., Strand, A.D., Sengstag, T., Kooperberg, C., Becanovic, K., Pouladi, M.A., Sathasivam, K., Cha, J.H. et al. (2007) Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage. Hum. Mol. Genet., 16, 1845-1861.
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 1845-1861
-
-
Kuhn, A.1
Goldstein, D.R.2
Hodges, A.3
Strand, A.D.4
Sengstag, T.5
Kooperberg, C.6
Becanovic, K.7
Pouladi, M.A.8
Sathasivam, K.9
Cha, J.H.10
-
7
-
-
0033613212
-
Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells
-
Kazantsev, A., Preisinger, E., Dranovsky, A., Goldgaber, D. and Housman, D. (1999) Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells. Proc. Natl Acad. Sci. USA, 96, 11404-11409.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 11404-11409
-
-
Kazantsev, A.1
Preisinger, E.2
Dranovsky, A.3
Goldgaber, D.4
Housman, D.5
-
8
-
-
12944263711
-
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
-
Steffan, J.S., Kazantsev, A., Spasic-Boskovic, O., Greenwald, M., Zhu, Y.Z., Gohler, H., Wanker, E.E., Bates, G.P., Housman, D.E. and Thompson, L.M. (2000) The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription. Proc. Natl Acad. Sci. USA, 97, 6763-6768.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 6763-6768
-
-
Steffan, J.S.1
Kazantsev, A.2
Spasic-Boskovic, O.3
Greenwald, M.4
Zhu, Y.Z.5
Gohler, H.6
Wanker, E.E.7
Bates, G.P.8
Housman, D.E.9
Thompson, L.M.10
-
9
-
-
0035937523
-
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity
-
Nucifora, F.C. Jr, Sasaki, M., Peters, M.F., Huang, H., Cooper, J.K., Yamada, M., Takahashi, H., Tsuji, S., Troncoso, J., Dawson, V.L. et al. (2001) Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science, 291, 2423-2428.
-
(2001)
Science
, vol.291
, pp. 2423-2428
-
-
Nucifora, F.C.1
Sasaki, M.2
Peters, M.F.3
Huang, H.4
Cooper, J.K.5
Yamada, M.6
Takahashi, H.7
Tsuji, S.8
Troncoso, J.9
Dawson, V.L.10
-
10
-
-
0032450856
-
Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins
-
Huang, C.C., Faber, P.W., Persichetti, F., Mittal, V., Vonsattel, J.P., MacDonald, M.E. and Gusella, J.F. (1998) Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins. Somatic Cell Mol. Genet., 24, 217-233.
-
(1998)
Somatic Cell Mol. Genet.
, vol.24
, pp. 217-233
-
-
Huang, C.C.1
Faber, P.W.2
Persichetti, F.3
Mittal, V.4
Vonsattel, J.P.5
MacDonald, M.E.6
Gusella, J.F.7
-
11
-
-
0037150687
-
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease
-
Dunah, A.W., Jeong, H., Griffin, A., Kim, Y.M., Standaert, D.G., Hersch, S.M., Mouradian, M.M., Young, A.B., Tanese, N. and Krainc, D. (2002) Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease. Science, 296, 2238-2243.
-
(2002)
Science
, vol.296
, pp. 2238-2243
-
-
Dunah, A.W.1
Jeong, H.2
Griffin, A.3
Kim, Y.M.4
Standaert, D.G.5
Hersch, S.M.6
Mouradian, M.M.7
Young, A.B.8
Tanese, N.9
Krainc, D.10
-
12
-
-
0036173896
-
Interaction of Huntington disease protein with transcriptional activator Sp1
-
Li, S.H., Cheng, A.L., Zhou, H., Lam, S., Rao, M., Li, H. and Li, X.J. (2002) Interaction of Huntington disease protein with transcriptional activator Sp1. Mol. Cell. Biol., 22, 1277-1287.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1277-1287
-
-
Li, S.H.1
Cheng, A.L.2
Zhou, H.3
Lam, S.4
Rao, M.5
Li, H.6
Li, X.J.7
-
13
-
-
0032833981
-
Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin
-
Boutell, J.M., Thomas, P., Neal, J.W., Weston, V.J., Duce, J., Harper, P.S. and Jones, A.L. (1999) Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin. Hum. Mol. Genet., 8, 1647-1655.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 1647-1655
-
-
Boutell, J.M.1
Thomas, P.2
Neal, J.W.3
Weston, V.J.4
Duce, J.5
Harper, P.S.6
Jones, A.L.7
-
14
-
-
0142153442
-
Analysis of cellular, transgenic and human models of Huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology
-
Yohrling, G.J.T., Jiang, G.C., DeJohn, M.M., Miller, D.W., Young, A.B., Vrana, K.E. and Cha, J.H. (2003) Analysis of cellular, transgenic and human models of Huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology. Brain Res. Mol. Brain Res., 119, 28-36.
-
(2003)
Brain Res. Mol. Brain Res.
, vol.119
, pp. 28-36
-
-
Yohrling, G.J.T.1
Jiang, G.C.2
DeJohn, M.M.3
Miller, D.W.4
Young, A.B.5
Vrana, K.E.6
Cha, J.H.7
-
15
-
-
40949135766
-
Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor
-
Yamanaka, T., Miyazaki, H., Oyama, F., Kurosawa, M., Washizu, C., Doi, H. and Nukina, N. (2008) Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor. EMBO J., 27, 827-839.
-
(2008)
EMBO J.
, vol.27
, pp. 827-839
-
-
Yamanaka, T.1
Miyazaki, H.2
Oyama, F.3
Kurosawa, M.4
Washizu, C.5
Doi, H.6
Nukina, N.7
-
16
-
-
18544368523
-
Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription
-
Kegel, K.B., Meloni, A.R., Yi, Y., Kim, Y.J., Doyle, E., Cuiffo, B.G., Sapp, E., Wang, Y., Qin, Z.H., Chen, J.D. et al. (2002) Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription. J. Biol. Chem., 277, 7466-7476.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7466-7476
-
-
Kegel, K.B.1
Meloni, A.R.2
Yi, Y.3
Kim, Y.J.4
Doyle, E.5
Cuiffo, B.G.6
Sapp, E.7
Wang, Y.8
Qin, Z.H.9
Chen, J.D.10
-
17
-
-
0041353535
-
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
-
Zuccato, C., Tartari, M., Crotti, A., Goffredo, D., Valenza, M., Conti, L., Cataudella, T., Leavitt, B.R., Hayden, M.R., Timmusk, T. et al. (2003) Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes. Nat. Genet., 35, 76-83.
-
(2003)
Nat. Genet.
, vol.35
, pp. 76-83
-
-
Zuccato, C.1
Tartari, M.2
Crotti, A.3
Goffredo, D.4
Valenza, M.5
Conti, L.6
Cataudella, T.7
Leavitt, B.R.8
Hayden, M.R.9
Timmusk, T.10
-
18
-
-
58149375393
-
The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease
-
Packer, A.N., Xing, Y., Harper, S.Q., Jones, L. and Davidson, B.L. (2008) The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease. J. Neurosci., 28, 14341-14346.
-
(2008)
J. Neurosci.
, vol.28
, pp. 14341-14346
-
-
Packer, A.N.1
Xing, Y.2
Harper, S.Q.3
Jones, L.4
Davidson, B.L.5
-
19
-
-
0035852687
-
The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in huntington's disease pathogenesis
-
Holbert, S., Denghien, I., Kiechle, T., Rosenblatt, A., Wellington, C., Hayden, M.R., Margolis, R.L., Ross, C.A., Dausset, J., Ferrante, R.J. et al. (2001) The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in huntington's disease pathogenesis. Proc. Natl Acad. Sci. USA, 98, 1811-1816.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 1811-1816
-
-
Holbert, S.1
Denghien, I.2
Kiechle, T.3
Rosenblatt, A.4
Wellington, C.5
Hayden, M.R.6
Margolis, R.L.7
Ross, C.A.8
Dausset, J.9
Ferrante, R.J.10
-
20
-
-
0032830639
-
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
-
Amir, R.E., Van den Veyver, I.B., Wan, M., Tran, C.Q., Francke, U. and Zoghbi, H.Y. (1999) Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet., 23, 185-188.
-
(1999)
Nat. Genet.
, vol.23
, pp. 185-188
-
-
Amir, R.E.1
Van den Veyver, I.B.2
Wan, M.3
Tran, C.Q.4
Francke, U.5
Zoghbi, H.Y.6
-
21
-
-
33744731756
-
Identification of cis-regulatory elements for MECP2 expression
-
Liu, J. and Francke, U. (2006) Identification of cis-regulatory elements for MECP2 expression. Hum. Mol. Genet., 15, 1769-1782.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 1769-1782
-
-
Liu, J.1
Francke, U.2
-
22
-
-
33646683567
-
MeCP2 dysfunction in Rett syndrome and related disorders
-
Moretti, P. and Zoghbi, H.Y. (2006) MeCP2 dysfunction in Rett syndrome and related disorders. Curr. Opin. Genet. Dev., 16, 276-281.
-
(2006)
Curr. Opin. Genet. Dev.
, vol.16
, pp. 276-281
-
-
Moretti, P.1
Zoghbi, H.Y.2
-
23
-
-
0026747761
-
Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA
-
Lewis, J.D., Meehan, R.R., Henzel, W.J., Maurer-Fogy, I., Jeppesen, P., Klein, F. and Bird, A. (1992) Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA. Cell, 69, 905-914.
-
(1992)
Cell
, vol.69
, pp. 905-914
-
-
Lewis, J.D.1
Meehan, R.R.2
Henzel, W.J.3
Maurer-Fogy, I.4
Jeppesen, P.5
Klein, F.6
Bird, A.7
-
24
-
-
0026658662
-
Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA
-
Meehan, R.R., Lewis, J.D. and Bird, A.P. (1992) Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA. Nucleic. Acids. Res., 20, 5085-5092.
-
(1992)
Nucleic. Acids. Res.
, vol.20
, pp. 5085-5092
-
-
Meehan, R.R.1
Lewis, J.D.2
Bird, A.P.3
-
25
-
-
33646893456
-
Molecular genetics of Rett syndrome: when DNA methylation goes unrecognized
-
Bienvenu, T. and Chelly, J. (2006) Molecular genetics of Rett syndrome: when DNA methylation goes unrecognized. Nat. Rev. Genet., 7, 415-426.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 415-426
-
-
Bienvenu, T.1
Chelly, J.2
-
26
-
-
0642336945
-
Molecular biology. MeCP2 repression goes nonglobal.
-
Klose, R. and Bird, A. (2003) Molecular biology. MeCP2 repression goes nonglobal. Science, 302, 793-795.
-
(2003)
Science
, vol.302
, pp. 793-795
-
-
Klose, R.1
Bird, A.2
-
27
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
-
Nan, X., Ng, H.H., Johnson, C.A., Laherty, C.D., Turner, B.M., Eisenman, R.N. and Bird, A. (1998) Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature, 393, 386-389.
-
(1998)
Nature
, vol.393
, pp. 386-389
-
-
Nan, X.1
Ng, H.H.2
Johnson, C.A.3
Laherty, C.D.4
Turner, B.M.5
Eisenman, R.N.6
Bird, A.7
-
28
-
-
0037423186
-
The methyl-CpG-binding protein MeCP2 linksDNAmethylation to histone methylation
-
Fuks, F., Hurd, P.J., Wolf, D., Nan, X., Bird, A.P. and Kouzarides, T. (2003) The methyl-CpG-binding protein MeCP2 linksDNAmethylation to histone methylation. J. Biol. Chem., 278, 4035-4040.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 4035-4040
-
-
Fuks, F.1
Hurd, P.J.2
Wolf, D.3
Nan, X.4
Bird, A.P.5
Kouzarides, T.6
-
29
-
-
54849422301
-
Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly=to DNA in a polyglutamine-dependent manner
-
Benn, C.L., Sun, T., Sadri-Vakili, G., McFarland, K.N., DiRocco, D.P., Yohrling, G.J., Clark, T.W., Bouzou, B. and Cha, J.H. (2008) Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly=to DNA in a polyglutamine-dependent manner. J. Neurosci., 28, 10720-10733.
-
(2008)
J. Neurosci.
, vol.28
, pp. 10720-10733
-
-
Benn, C.L.1
Sun, T.2
Sadri-Vakili, G.3
McFarland, K.N.4
DiRocco, D.P.5
Yohrling, G.J.6
Clark, T.W.7
Bouzou, B.8
Cha, J.H.9
-
30
-
-
43049168861
-
Altered histone monoubiquitylation mediated by mutant huntingtin induces transcriptional dysregulation
-
Kim, M.O., Chawla, P., Overland, R.P., Xia, E., Sadri-Vakili, G. and Cha, J.H. (2008) Altered histone monoubiquitylation mediated by mutant huntingtin induces transcriptional dysregulation. J. Neurosci., 28, 3947-3957.
-
(2008)
J. Neurosci.
, vol.28
, pp. 3947-3957
-
-
Kim, M.O.1
Chawla, P.2
Overland, R.P.3
Xia, E.4
Sadri-Vakili, G.5
Cha, J.H.6
-
31
-
-
40949125214
-
Visualizing interaction of proteins relevant to Alzheimer's disease in intact cells
-
Thomas, A.V., Berezovska, O., Hyman, B.T. and von Arnim, C.A. (2008) Visualizing interaction of proteins relevant to Alzheimer's disease in intact cells. Methods, 44, 299-303.
-
(2008)
Methods
, vol.44
, pp. 299-303
-
-
Thomas, A.V.1
Berezovska, O.2
Hyman, B.T.3
von Arnim, C.A.4
-
32
-
-
34548799689
-
MeCP2 interacts with HP1 and modulates its heterochromatin association during myogenic differentiation
-
Agarwal, N., Hardt, T., Brero, A., Nowak, D., Rothbauer, U., Becker, A., Leonhardt, H. and Cardoso, M.C. (2007) MeCP2 interacts with HP1 and modulates its heterochromatin association during myogenic differentiation. Nucleic. Acids. Res., 35, 5402-5408.
-
(2007)
Nucleic. Acids. Res.
, vol.35
, pp. 5402-5408
-
-
Agarwal, N.1
Hardt, T.2
Brero, A.3
Nowak, D.4
Rothbauer, U.5
Becker, A.6
Leonhardt, H.7
Cardoso, M.C.8
-
33
-
-
0035919701
-
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
-
Zuccato, C., Ciammola, A., Rigamonti, D., Leavitt, B.R., Goffredo, D., Conti, L., MacDonald, M.E., Friedlander, R.M., Silani, V., Hayden, M.R. et al. (2001) Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease. Science, 293, 493-498.
-
(2001)
Science
, vol.293
, pp. 493-498
-
-
Zuccato, C.1
Ciammola, A.2
Rigamonti, D.3
Leavitt, B.R.4
Goffredo, D.5
Conti, L.6
MacDonald, M.E.7
Friedlander, R.M.8
Silani, V.9
Hayden, M.R.10
-
34
-
-
0242332183
-
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
-
Chen, W.G., Chang, Q., Lin, Y., Meissner, A., West, A.E., Griffith, E.C., Jaenisch, R. and Greenberg, M.E. (2003) Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. Science, 302, 885-889.
-
(2003)
Science
, vol.302
, pp. 885-889
-
-
Chen, W.G.1
Chang, Q.2
Lin, Y.3
Meissner, A.4
West, A.E.5
Griffith, E.C.6
Jaenisch, R.7
Greenberg, M.E.8
-
35
-
-
0242300612
-
DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation
-
Martinowich, K., Hattori, D., Wu, H., Fouse, S., He, F., Hu, Y., Fan, G. and Sun, Y.E. (2003) DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science, 302, 890-893.
-
(2003)
Science
, vol.302
, pp. 890-893
-
-
Martinowich, K.1
Hattori, D.2
Wu, H.3
Fouse, S.4
He, F.5
Hu, Y.6
Fan, G.7
Sun, Y.E.8
-
36
-
-
0026547235
-
Fluorescence lifetime imaging of free and protein-bound NADH
-
Lakowicz, J.R., Szmacinski, H., Nowaczyk, K. and Johnson, M.L. (1992) Fluorescence lifetime imaging of free and protein-bound NADH. Proc. Natl Acad. Sci. USA, 89, 1271-1275.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 1271-1275
-
-
Lakowicz, J.R.1
Szmacinski, H.2
Nowaczyk, K.3
Johnson, M.L.4
-
37
-
-
0036164650
-
Nanosecond fluorescence resonance energy transfer-fluorescence lifetime imaging microscopy to localize the protein interactions in a single living cell
-
Elangovan, M., Day, R.N. and Periasamy, A. (2002) Nanosecond fluorescence resonance energy transfer-fluorescence lifetime imaging microscopy to localize the protein interactions in a single living cell. J. Microsc., 205, 3-14.
-
(2002)
J. Microsc.
, vol.205
, pp. 3-14
-
-
Elangovan, M.1
Day, R.N.2
Periasamy, A.3
-
38
-
-
84855816126
-
Modification of Mecp2 dosage alters axonal transport through the Huntingtin/Hap1 pathway
-
Roux, J.C., Zala, D., Panayotis, N., Borges-Correia, A., Saudou, F. and Villard, L. (2012) Modification of Mecp2 dosage alters axonal transport through the Huntingtin/Hap1 pathway. Neurobiol. Dis., 45, 786-795.
-
(2012)
Neurobiol. Dis.
, vol.45
, pp. 786-795
-
-
Roux, J.C.1
Zala, D.2
Panayotis, N.3
Borges-Correia, A.4
Saudou, F.5
Villard, L.6
-
39
-
-
0034927081
-
Neurotrophins: roles in neuronal development and function
-
Huang, E.J. and Reichardt, L.F. (2001) Neurotrophins: roles in neuronal development and function. Ann. Rev. Neurosci., 24, 677-736.
-
(2001)
Ann. Rev. Neurosci.
, vol.24
, pp. 677-736
-
-
Huang, E.J.1
Reichardt, L.F.2
-
40
-
-
0035234670
-
Neurotrophins as synaptic modulators
-
Poo, M.M. (2001) Neurotrophins as synaptic modulators. Nat Rev Neurosci, 2, 24-32.
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 24-32
-
-
Poo, M.M.1
-
41
-
-
23044515099
-
Functions and mechanisms of retrograde neurotrophin signalling
-
Zweifel, L.S., Kuruvilla, R. and Ginty, D.D. (2005) Functions and mechanisms of retrograde neurotrophin signalling. Nat. Rev. Neurosci., 6, 615-625.
-
(2005)
Nat. Rev. Neurosci.
, vol.6
, pp. 615-625
-
-
Zweifel, L.S.1
Kuruvilla, R.2
Ginty, D.D.3
-
42
-
-
3142636768
-
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules
-
Gauthier, L.R., Charrin, B.C., Borrell-Pages, M., Dompierre, J.P., Rangone, H., Cordelieres, F.P., De Mey, J., MacDonald, M.E., Lessmann, V., Humbert, S. et al. (2004) Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell, 118, 127-138.
-
(2004)
Cell
, vol.118
, pp. 127-138
-
-
Gauthier, L.R.1
Charrin, B.C.2
Borrell-Pages, M.3
Dompierre, J.P.4
Rangone, H.5
Cordelieres, F.P.6
De Mey, J.7
MacDonald, M.E.8
Lessmann, V.9
Humbert, S.10
-
43
-
-
84863248297
-
Truncated N-terminal huntingtin fragment with expanded-polyglutamine (htt552-100Q) suppresses brain-derived neurotrophic factor transcription in astrocytes
-
Wang, L., Lin, F., Wang, J., Wu, J., Han, R., Zhu, L., Zhang, G., Difiglia, M. and Qin, Z. (2012) Truncated N-terminal huntingtin fragment with expanded-polyglutamine (htt552-100Q) suppresses brain-derived neurotrophic factor transcription in astrocytes. Acta. Biochim. Biophys. Sin., 44, 249-258.
-
(2012)
Acta. Biochim. Biophys. Sin.
, vol.44
, pp. 249-258
-
-
Wang, L.1
Lin, F.2
Wang, J.3
Wu, J.4
Han, R.5
Zhu, L.6
Zhang, G.7
Difiglia, M.8
Qin, Z.9
-
44
-
-
33749590330
-
Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation
-
Zhou, Z., Hong, E.J., Cohen, S., Zhao, W.N., Ho, H.Y., Schmidt, L., Chen, W.G., Lin, Y., Savner, E., Griffith, E.C. et al. (2006) Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation. Neuron, 52, 255-269.
-
(2006)
Neuron
, vol.52
, pp. 255-269
-
-
Zhou, Z.1
Hong, E.J.2
Cohen, S.3
Zhao, W.N.4
Ho, H.Y.5
Schmidt, L.6
Chen, W.G.7
Lin, Y.8
Savner, E.9
Griffith, E.C.10
-
45
-
-
76849094693
-
Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state
-
Skene, P.J., Illingworth, R.S., Webb, S., Kerr, A.R., James, K.D., Turner, D.J., Andrews, R. and Bird, A.P. (2010) Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state. Mol. Cell, 37 457-468.
-
(2010)
Mol. Cell
, vol.37
, pp. 457-468
-
-
Skene, P.J.1
Illingworth, R.S.2
Webb, S.3
Kerr, A.R.4
James, K.D.5
Turner, D.J.6
Arews, R.7
Bird, A.P.8
-
46
-
-
0034163497
-
Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice
-
Wheeler, V.C., White, J.K., Gutekunst, C.A., Vrbanac, V., Weaver, M., Li, X.J., Li, S.H., Yi, H., Vonsattel, J.P., Gusella, J.F. et al. (2000) Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice. Hum. Mol. Genet., 9, 503-513.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 503-513
-
-
Wheeler, V.C.1
White, J.K.2
Gutekunst, C.A.3
Vrbanac, V.4
Weaver, M.5
Li, X.J.6
Li, S.H.7
Yi, H.8
Vonsattel, J.P.9
Gusella, J.F.10
-
47
-
-
0034703869
-
Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells
-
Trettel, F., Rigamonti, D., Hilditch-Maguire, P., Wheeler, V.C., Sharp, A.H., Persichetti, F., Cattaneo, E. and MacDonald, M.E. (2000) Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells. Hum. Mol. Genet., 9, 2799-2809.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2799-2809
-
-
Trettel, F.1
Rigamonti, D.2
Hilditch-Maguire, P.3
Wheeler, V.C.4
Sharp, A.H.5
Persichetti, F.6
Cattaneo, E.7
MacDonald, M.E.8
-
48
-
-
0141644224
-
Fluorescence resonance energy transfer determinations using multiphoton fluorescence lifetime imaging microscopy to characterize amyloid-beta plaques
-
Bacskai, B.J., Skoch, J., Hickey, G.A., Allen, R. and Hyman, B.T. (2003) Fluorescence resonance energy transfer determinations using multiphoton fluorescence lifetime imaging microscopy to characterize amyloid-beta plaques. J. Biomed. Opt., 8, 368-375.
-
(2003)
J. Biomed. Opt.
, vol.8
, pp. 368-375
-
-
Bacskai, B.J.1
Skoch, J.2
Hickey, G.A.3
Allen, R.4
Hyman, B.T.5
-
49
-
-
15244341378
-
Familial Alzheimer's disease presenilin 1 mutations cause alterations in the conformation of presenilin and interactions with amyloid precursor protein
-
Berezovska, O., Lleo, A., Herl, L.D., Frosch, M.P., Stern, E.A., Bacskai, B.J. and Hyman, B.T. (2005) Familial Alzheimer's disease presenilin 1 mutations cause alterations in the conformation of presenilin and interactions with amyloid precursor protein. J. Neurosci., 25, 3009-3017.
-
(2005)
J. Neurosci.
, vol.25
, pp. 3009-3017
-
-
Berezovska, O.1
Lleo, A.2
Herl, L.D.3
Frosch, M.P.4
Stern, E.A.5
Bacskai, B.J.6
Hyman, B.T.7
-
50
-
-
77956243007
-
Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine
-
Sadri-Vakili, G., Kumaresan, V., Schmidt, H.D., Famous, K.R., Chawla, P., Vassoler, F.M., Overland, R.P., Xia, E., Bass, C.E., Terwilliger, E.F. et al. (2010) Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine. J. Neurosci., 30, 11735-11744.
-
(2010)
J. Neurosci.
, vol.30
, pp. 11735-11744
-
-
Sadri-Vakili, G.1
Kumaresan, V.2
Schmidt, H.D.3
Famous, K.R.4
Chawla, P.5
Vassoler, F.M.6
Overland, R.P.7
Xia, E.8
Bass, C.E.9
Terwilliger, E.F.10
-
51
-
-
33646137562
-
Decreased association of the transcription factor Sp1 with genes downregulated in Huntington's disease
-
Chen-Plotkin, A.S., Sadri-Vakili, G., Yohrling, G.J., Braveman, M.W., Benn, C.L., Glajch, K.E., DiRocco, D.P., Farrell, L.A., Krainc, D., Gines, S. et al. (2006) Decreased association of the transcription factor Sp1 with genes downregulated in Huntington's disease. Neurobiol. Dis., 22, 233-241.
-
(2006)
Neurobiol. Dis.
, vol.22
, pp. 233-241
-
-
Chen-Plotkin, A.S.1
Sadri-Vakili, G.2
Yohrling, G.J.3
Braveman, M.W.4
Benn, C.L.5
Glajch, K.E.6
DiRocco, D.P.7
Farrell, L.A.8
Krainc, D.9
Gines, S.10
-
52
-
-
38749154696
-
BHLHB2 Controls Bdnf promoter 4 activity and neuronal excitability
-
Jiang, X., Tian, F., Du, Y., Copeland, N.G., Jenkins, N.A., Tessarollo, L., Wu, X., Pan, H., Hu, X.Z., Xu, K. et al. (2008) BHLHB2 Controls Bdnf promoter 4 activity and neuronal excitability. J. Neurosci., 28, 1118-1130.
-
(2008)
J. Neurosci.
, vol.28
, pp. 1118-1130
-
-
Jiang, X.1
Tian, F.2
Du, Y.3
Copeland, N.G.4
Jenkins, N.A.5
Tessarollo, L.6
Wu, X.7
Pan, H.8
Hu, X.Z.9
Xu, K.10
-
53
-
-
84155167228
-
Increased brain-derived neurotrophic factor (BDNF) expression in the ventral tegmental area during cocaine abstinence is associated with increased histone acetylation atBDNF exon I-containing promoters
-
Schmidt, H.D., Sangrey, G.R., Darnell, S.B., Schassburger, R.L., Cha, J.H., Pierce, R.C. and Sadri-Vakili, G. (2012) Increased brain-derived neurotrophic factor (BDNF) expression in the ventral tegmental area during cocaine abstinence is associated with increased histone acetylation atBDNF exon I-containing promoters. J. Neurochem., 120, 202-209.
-
(2012)
J. Neurochem.
, vol.120
, pp. 202-209
-
-
Schmidt, H.D.1
Sangrey, G.R.2
Darnell, S.B.3
Schassburger, R.L.4
Cha, J.H.5
Pierce, R.C.6
Sadri-Vakili, G.7
-
54
-
-
33847250395
-
Mouse, rat BDNF gene structure and expression revisited
-
Aid, T., Kazantseva, A., Piirsoo, M., Palm, K. and Timmusk, T. (2007) Mouse and rat BDNF gene structure and expression revisited. J. Neurosci. Res., 85, 525-535.
-
(2007)
J. Neurosci. Res.
, vol.85
, pp. 525-535
-
-
Aid, T.1
Kazantseva, A.2
Piirsoo, M.3
Palm, K.4
Timmusk, T.5
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