Increased brain-derived neurotrophic factor (BDNF) expression in the ventral tegmental area during cocaine abstinence is associated with increased histone acetylation at BDNF exon I-containing promoters

Journal of Neurochemistry

Volumn 120, Issue 2, 2012, Pages 202-209

  Schmidt, Heath D ^a   Sangrey, Gavin R ^b   Darnell, Shayna B ^b   Schassburger, Rachel L ^a   Cha, Jang Ho J ^b   Pierce, R Christopher ^a   Sadri Vakili, Ghazaleh ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

addiction; chromatin remodeling; neurotrophic factor; psychostimulant; self administration; transcription

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; COCAINE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HISTONE ACETYLTRANSFERASE; HISTONE H3;

5' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANTERIOR FONTANEL; ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; DRUG SELF ADMINISTRATION; DRUG WITHDRAWAL; ENZYME LINKED IMMUNOSORBENT ASSAY; EXON; HISTONE ACETYLATION; MALE; MESENCEPHALON; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; REINFORCEMENT; RELAPSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VENTRAL TEGMENTUM;

ACETYLATION; ANESTHETICS, LOCAL; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CHROMATIN IMMUNOPRECIPITATION; COCAINE; COCAINE-RELATED DISORDERS; CONDITIONING, OPERANT; CREB-BINDING PROTEIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HISTONES; MALE; PROMOTER REGIONS, GENETIC; RATS; RATS, SPRAGUE-DAWLEY; REINFORCEMENT SCHEDULE; RNA, MESSENGER; SELF ADMINISTRATION; STATISTICS, NONPARAMETRIC; SUBSTANCE WITHDRAWAL SYNDROME; TIME FACTORS; VENTRAL TEGMENTAL AREA;

RATTUS;

EID: 84155167228     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07571.x     Document Type: Article

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