Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor

EMBO Journal

Volumn 27, Issue 6, 2008, Pages 827-839

  Yamanaka, Tomoyuki ^a,b   Miyazaki, Haruko ^a   Oyama, Fumitaka ^a   Kurosawa, Masaru ^a   Washizu, Chika ^a   Doi, Hiroshi ^a   Nukina, Nobuyuki ^a  

^a RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^b RIKEN   (Japan)

Author keywords

Heat shock protein; Huntington's disease; NF Y; Transcription

Indexed keywords

HEAT SHOCK PROTEIN 70; HUNTINGTIN; NUCLEAR FACTOR Y; NUCLEIC ACID BINDING PROTEIN; PROTEIN NFYA; PROTEIN NFYC; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; GEL MOBILITY SHIFT ASSAY; HUNTINGTON CHOREA; MALE; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CCAAT-BINDING FACTOR; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; HSP70 HEAT-SHOCK PROTEINS; HUNTINGTON DISEASE; MALE; MICE; MICE, TRANSGENIC; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PROTEIN BINDING;

MUS;

EID: 40949135766     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2008.23     Document Type: Article

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