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Volumn 114, Issue 1, 2014, Pages 67-78

MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblasts

Author keywords

Anoxia; hypertension; migration; neoplasms; proliferation; pulmonary

Indexed keywords

APICIDIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; HISTONE DEACETYLASE; MICRORNA 124; MONOCYTE CHEMOTACTIC PROTEIN 1; NOTCH1 RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; POLYPYRIMIDINE TRACT BINDING PROTEIN; TRANSCRIPTION FACTOR FKHRL1; VORINOSTAT;

EID: 84892930632     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.114.301633     Document Type: Article
Times cited : (189)

References (80)
  • 1
    • 67649844313 scopus 로고    scopus 로고
    • Infammation, growth factors, and pulmonary vascular remodeling
    • Hassoun PM, Mouthon L, Barberà JA, et al. Infammation, growth factors, and pulmonary vascular remodeling. J Am Coll Cardiol. 2009;54:S10-S19.
    • (2009) J Am Coll Cardiol. , vol.54
    • Hassoun, P.M.1    Mouthon, L.2    Barberà, J.A.3
  • 5
    • 0035880173 scopus 로고    scopus 로고
    • Chronic hypoxia induces constitutive p38 mitogen-activated protein kinase activity that correlates with enhanced cellular proliferation in fbroblasts from rat pulmonary but not systemic arteries
    • Welsh DJ, Peacock AJ, MacLean M, Harnett M. Chronic hypoxia induces constitutive p38 mitogen-activated protein kinase activity that correlates with enhanced cellular proliferation in fbroblasts from rat pulmonary but not systemic arteries. Am J Respir Crit Care Med. 2001;164:282-289.
    • (2001) Am J Respir Crit Care Med. , vol.164 , pp. 282-289
    • Welsh, D.J.1    Peacock, A.J.2    Maclean, M.3    Harnett, M.4
  • 6
    • 80054908979 scopus 로고    scopus 로고
    • Myofbroblast-mediated adventitial remodeling: An underestimated player in arterial pathology
    • Coen M, Gabbiani G, Bochaton-Piallat ML. Myofbroblast-mediated adventitial remodeling: an underestimated player in arterial pathology. Arterioscler Thromb Vasc Biol. 2011;31:2391-2396.
    • (2011) Arterioscler Thromb Vasc Biol. , vol.31 , pp. 2391-2396
    • Coen, M.1    Gabbiani, G.2    Bochaton-Piallat, M.L.3
  • 7
    • 0035824921 scopus 로고    scopus 로고
    • Contribution of adventitial fbroblasts to neointima formation and vascular remodeling: From innocent bystander to active participant
    • Sartore S, Chiavegato A, Faggin E, Franch R, Puato M, Ausoni S, Pauletto P. Contribution of adventitial fbroblasts to neointima formation and vascular remodeling: from innocent bystander to active participant. Circ Res. 2001;89:1111-1121.
    • (2001) Circ Res. , vol.89 , pp. 1111-1121
    • Sartore, S.1    Chiavegato, A.2    Faggin, E.3    Franch, R.4    Puato, M.5    Ausoni, S.6    Pauletto, P.7
  • 13
    • 80052667354 scopus 로고    scopus 로고
    • Emergence of fbroblasts with a proin-fammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension
    • Li M, Riddle SR, Frid MG, et al. Emergence of fbroblasts with a proin-fammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension. J Immunol. 2011;187:2711-2722.
    • (2011) J Immunol. , vol.187 , pp. 2711-2722
    • Li, M.1    Riddle, S.R.2    Frid, M.G.3
  • 15
    • 39749110083 scopus 로고    scopus 로고
    • Small non-coding RNAs in animal development
    • Stefani G, Slack FJ. Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol. 2008;9:219-230.
    • (2008) Nat Rev Mol Cell Biol. , vol.9 , pp. 219-230
    • Stefani, G.1    Slack, F.J.2
  • 16
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116:281-297.
    • (2004) Cell. , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 17
    • 58849163959 scopus 로고    scopus 로고
    • MicroRNAs: Key regulators of stem cells
    • Gangaraju VK, Lin H. MicroRNAs: key regulators of stem cells. Nat Rev Mol Cell Biol. 2009;10:116-125.
    • (2009) Nat Rev Mol Cell Biol. , vol.10 , pp. 116-125
    • Gangaraju, V.K.1    Lin, H.2
  • 18
    • 79961095592 scopus 로고    scopus 로고
    • Biogenesis and regulation of cardiovascular mi-croRNAs
    • Bauersachs J, Thum T. Biogenesis and regulation of cardiovascular mi-croRNAs. Circ Res. 2011;109:334-347.
    • (2011) Circ Res. , vol.109 , pp. 334-347
    • Bauersachs, J.1    Thum, T.2
  • 19
    • 84858126071 scopus 로고    scopus 로고
    • MicroRNA dysregulation in cancer: Diagnostics, monitoring and therapeutics. A comprehensive review
    • Iorio MV, Croce CM. MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review. EMBO Mol Med. 2012;4:143-159.
    • (2012) EMBO Mol Med. , vol.4 , pp. 143-159
    • Iorio, M.V.1    Croce, C.M.2
  • 20
    • 84857932052 scopus 로고    scopus 로고
    • Role of microRNAs in diabetes and its cardiovascular complications
    • Shantikumar S, Caporali A, Emanueli C. Role of microRNAs in diabetes and its cardiovascular complications. Cardiovasc Res. 2012;93:583-593.
    • (2012) Cardiovasc Res. , vol.93 , pp. 583-593
    • Shantikumar, S.1    Caporali, A.2    Emanueli, C.3
  • 21
    • 84857582662 scopus 로고    scopus 로고
    • Differential expression of microRNAs in different disease states
    • Abdellatif M. Differential expression of microRNAs in different disease states. Circ Res. 2012;110:638-650.
    • (2012) Circ Res. , vol.110 , pp. 638-650
    • Abdellatif, M.1
  • 22
    • 78751660177 scopus 로고    scopus 로고
    • Pervasive roles of microRNAs in cardiovascular biology
    • Small EM, Olson EN. Pervasive roles of microRNAs in cardiovascular biology. Nature. 2011;469:336-342.
    • (2011) Nature. , vol.469 , pp. 336-342
    • Small, E.M.1    Olson, E.N.2
  • 23
    • 84880758429 scopus 로고    scopus 로고
    • Holding our breath: The emerging and anticipated roles of microRNA in pulmonary hypertension
    • White K, Loscalzo J, Chan S Y. Holding our breath: the emerging and anticipated roles of microRNA in pulmonary hypertension. Pulm Circ. 2012;2:278-290.
    • (2012) Pulm Circ. , vol.2 , pp. 278-290
    • White, K.1    Loscalzo, J.2    Chan, S.Y.3
  • 26
    • 84864229176 scopus 로고    scopus 로고
    • A role for miR-145 in pulmonary arterial hypertension: Evidence from mouse models and patient samples
    • Caruso P, Dempsie Y, Stevens HC, et al. A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples. Circ Res. 2012;111:290-300.
    • (2012) Circ Res. , vol.111 , pp. 290-300
    • Caruso, P.1    Dempsie, Y.2    Stevens, H.C.3
  • 27
    • 84883426400 scopus 로고    scopus 로고
    • MicroRNA-124 suppresses the transactivation of nuclear factor of activated T cells by targeting multiple genes and inhibits the proliferation of pulmonary artery smooth muscle cells
    • Kang K, Peng X, Zhang X, Wang Y, Zhang L, Gao L, Weng T, Zhang H, Ramchandran R, Raj JU, Gou D, Liu L. MicroRNA-124 suppresses the transactivation of nuclear factor of activated T cells by targeting multiple genes and inhibits the proliferation of pulmonary artery smooth muscle cells. J Biol Chem. 2013;288:25414-25427.
    • (2013) J Biol Chem. , vol.288 , pp. 25414-25427
    • Kang, K.1    Peng, X.2    Zhang, X.3    Wang, Y.4    Zhang, L.5    Gao, L.6    Weng, T.7    Zhang, H.8    Ramchandran, R.9    Raj, J.U.10    Gou, D.11    Liu, L.12
  • 28
    • 84862777565 scopus 로고    scopus 로고
    • MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: Results of a network bioin-formatics approach
    • Parikh VN, Jin RC, Rabello S, et al. MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioin-formatics approach. Circulation. 2012;125:1520-1532.
    • (2012) Circulation. , vol.125 , pp. 1520-1532
    • Parikh, V.N.1    Jin, R.C.2    Rabello, S.3
  • 31
    • 84878214332 scopus 로고    scopus 로고
    • Downregulation of miR-124 promotes the growth and invasiveness of glioblastoma cells involving upregulation of PPP1R13L
    • Zhao WH, Wu SQ, Zhang YD. Downregulation of miR-124 promotes the growth and invasiveness of glioblastoma cells involving upregulation of PPP1R13L. Int J Mol Med. 2013;32:101-107.
    • (2013) Int J Mol Med. , vol.32 , pp. 101-107
    • Zhao, W.H.1    Wu, S.Q.2    Zhang, Y.D.3
  • 33
    • 84863718549 scopus 로고    scopus 로고
    • MiR-124 inhibits cell proliferation in gastric cancer through down-regulation of SPHK1
    • Xia J, Wu Z, Yu C, He W, Zheng H, He Y, Jian W, Chen L, Zhang L, Li W. miR-124 inhibits cell proliferation in gastric cancer through down-regulation of SPHK1. J Pathol. 2012;227:470-480.
    • (2012) J Pathol. , vol.227 , pp. 470-480
    • Xia, J.1    Wu, Z.2    Yu, C.3    He, W.4    Zheng, H.5    He, Y.6    Jian, W.7    Chen, L.8    Zhang, L.9    Li, W.10
  • 34
    • 66049112958 scopus 로고    scopus 로고
    • MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fbroblast-like synoviocytes from patients with rheumatoid arthritis
    • Nakamachi Y, Kawano S, Takenokuchi M, Nishimura K, Sakai Y, Chin T, Saura R, Kurosaka M, Kumagai S. MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fbroblast-like synoviocytes from patients with rheumatoid arthritis. Arthritis Rheum. 2009;60:1294-1304.
    • (2009) Arthritis Rheum. , vol.60 , pp. 1294-1304
    • Nakamachi, Y.1    Kawano, S.2    Takenokuchi, M.3    Nishimura, K.4    Sakai, Y.5    Chin, T.6    Saura, R.7    Kurosaka, M.8    Kumagai, S.9
  • 35
    • 79952994992 scopus 로고    scopus 로고
    • Nakamachi Y miR-124a as a key regulator of proliferation and MCP-1 secretion in synoviocytes from patients with rheumatoid arthritis
    • Kawano S, Nakamachi Y. miR-124a as a key regulator of proliferation and MCP-1 secretion in synoviocytes from patients with rheumatoid arthritis. Ann Rheum Dis. 2011;70(Suppl 1):i88-i91.
    • (2011) Ann Rheum Dis. , vol.70 , Issue.SUPPL. 1
    • Kawano, S.1
  • 36
    • 84862157083 scopus 로고    scopus 로고
    • Functional studies of microRNAs in neural stem cells: Problems and perspectives
    • Akerblom M, Sachdeva R, Jakobsson J. Functional studies of microRNAs in neural stem cells: problems and perspectives. Front Neurosci. 2012;6:14.
    • (2012) Front Neurosci. , vol.6 , pp. 14
    • Akerblom, M.1    Sachdeva, R.2    Jakobsson, J.3
  • 37
    • 77952002925 scopus 로고    scopus 로고
    • Ephrin-B1 reverse signaling controls a posttranscriptional feedback mechanism via miR-124
    • Arvanitis DN, Jungas T, Behar A, Davy A. Ephrin-B1 reverse signaling controls a posttranscriptional feedback mechanism via miR-124. Mol Cell Biol. 2010;30:2508-2517.
    • (2010) Mol Cell Biol. , vol.30 , pp. 2508-2517
    • Arvanitis, D.N.1    Jungas, T.2    Behar, A.3    Davy, A.4
  • 38
    • 33746322370 scopus 로고    scopus 로고
    • Polypyrimidine tract binding protein and Notch1 are independently re-expressed in glioma
    • Cheung HC, Corley LJ, Fuller GN, McCutcheon IE, Cote GJ. Polypyrimidine tract binding protein and Notch1 are independently re-expressed in glioma. Mod Pathol. 2006;19:1034-1041.
    • (2006) Mod Pathol. , vol.19 , pp. 1034-1041
    • Cheung, H.C.1    Corley, L.J.2    Fuller, G.N.3    McCutcheon, I.E.4    Cote, G.J.5
  • 39
    • 84868283518 scopus 로고    scopus 로고
    • Immune and infammatory cell involvement in the pathology of idiopathic pulmonary arterial hypertension
    • Savai R, Pullamsetti SS, Kolbe J, et al. Immune and infammatory cell involvement in the pathology of idiopathic pulmonary arterial hypertension. Am J Respir Crit Care Med. 2012;186:897-908.
    • (2012) Am J Respir Crit Care Med. , vol.186 , pp. 897-908
    • Savai, R.1    Pullamsetti, S.S.2    Kolbe, J.3
  • 40
    • 38349191617 scopus 로고    scopus 로고
    • CpG island hypermethylation of tumor suppressor microRNAs in human cancer
    • Lujambio A, Esteller M. CpG island hypermethylation of tumor suppressor microRNAs in human cancer. Cell Cycle. 2007;6:1455-1459.
    • (2007) Cell Cycle. , vol.6 , pp. 1455-1459
    • Lujambio, A.1    Esteller, M.2
  • 41
    • 77649171884 scopus 로고    scopus 로고
    • Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents
    • Tan J, Cang S, Ma Y, Petrillo RL, Liu D. Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents. J Hematol Oncol. 2010;3:5.
    • (2010) J Hematol Oncol. , vol.3 , pp. 5
    • Tan, J.1    Cang, S.2    Ma, Y.3    Petrillo, R.L.4    Liu, D.5
  • 42
    • 67649518730 scopus 로고    scopus 로고
    • An S. Suberoylanilide hydroxamic acid (SAHA) changes mi-croRNA expression profles in A549 human non-small cell lung cancer cells
    • Lee EM, Shin S, Cha HJ, Yoon Y, Bae S, Jung JH, Lee SM, Lee SJ, Park IC, Jin YW, An S. Suberoylanilide hydroxamic acid (SAHA) changes mi-croRNA expression profles in A549 human non-small cell lung cancer cells. Int J Mol Med. 2009;24:45-50.
    • (2009) Int J Mol Med. , vol.24 , pp. 45-50
    • Lee, E.M.1    Shin, S.2    Cha, H.J.3    Yoon, Y.4    Bae, S.5    Jung, J.H.6    Lee, S.M.7    Lee, S.J.8    Park, I.C.9    Jin, Y.W.10
  • 45
    • 33749345684 scopus 로고    scopus 로고
    • Hypoxia-induced pulmonary vascular remodeling: Cellular and molecular mechanisms
    • Stenmark KR, Fagan KA, Frid MG. Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms. Circ Res. 2006;99:675-691.
    • (2006) Circ Res. , vol.99 , pp. 675-691
    • Stenmark, K.R.1    Fagan, K.A.2    Frid, M.G.3
  • 46
  • 47
    • 84877783446 scopus 로고    scopus 로고
    • MicroRNA-138 plays a role in hypoxic pulmonary vascular remodelling by targeting Mst1
    • Li S, Ran Y, Zhang D, Chen J, Li S, Zhu D. MicroRNA-138 plays a role in hypoxic pulmonary vascular remodelling by targeting Mst1. Biochem J. 2013;452:281-291.
    • (2013) Biochem J. , vol.452 , pp. 281-291
    • Li, S.1    Ran, Y.2    Zhang, D.3    Chen, J.4    Li, S.5    Zhu, D.6
  • 48
    • 79957819926 scopus 로고    scopus 로고
    • MicroRNA and target protein patterns reveal physiopathological features of glioma subtypes
    • Lages E, Guttin A, El Atif M, et al. MicroRNA and target protein patterns reveal physiopathological features of glioma subtypes. PLoS One. 2011;6:e20600.
    • (2011) PLoS One. , vol.6
    • Lages, E.1    Guttin, A.2    El Atif, M.3
  • 49
    • 67749110060 scopus 로고    scopus 로고
    • Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines
    • Cheung HC, Hai T, Zhu W, Baggerly KA, Tsavachidis S, Krahe R, Cote GJ. Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines. Brain. 2009;132:2277-2288.
    • (2009) Brain. , vol.132 , pp. 2277-2288
    • Cheung, H.C.1    Hai, T.2    Zhu, W.3    Baggerly, K.A.4    Tsavachidis, S.5    Krahe, R.6    Cote, G.J.7
  • 51
    • 78549233413 scopus 로고    scopus 로고
    • Turning on a fuel switch of cancer: HnRNP proteins regulate alternative splicing of pyruvate kinase mRNA
    • Chen M, Zhang J, Manley JL. Turning on a fuel switch of cancer: hnRNP proteins regulate alternative splicing of pyruvate kinase mRNA. Cancer Res. 2010;70:8977-8980.
    • (2010) Cancer Res. , vol.70 , pp. 8977-8980
    • Chen, M.1    Zhang, J.2    Manley, J.L.3
  • 52
    • 0036168869 scopus 로고    scopus 로고
    • Translation of polioviral mRNA is inhibited by cleavage of polypyrimidine tract-binding proteins executed by polioviral 3C(pro)
    • Back SH, Kim YK, Kim WJ, Cho S, Oh HR, Kim JE, Jang SK. Translation of polioviral mRNA is inhibited by cleavage of polypyrimidine tract-binding proteins executed by polioviral 3C(pro). J Virol. 2002;76:2529-2542.
    • (2002) J Virol. , vol.76 , pp. 2529-2542
    • Back, S.H.1    Kim, Y.K.2    Kim, W.J.3    Cho, S.4    Oh, H.R.5    Kim, J.E.6    Jang, S.K.7
  • 54
    • 0029932545 scopus 로고    scopus 로고
    • The polypyrimidine tract binding (PTB) protein interacts with single-stranded DNA in a sequence-specifc manner
    • Brunel F, Zakin MM, Buc H, Buckle M. The polypyrimidine tract binding (PTB) protein interacts with single-stranded DNA in a sequence-specifc manner. Nucleic Acids Res. 1996;24:1608-1615.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 1608-1615
    • Brunel, F.1    Zakin, M.M.2    Buc, H.3    Buckle, M.4
  • 55
    • 77953169017 scopus 로고    scopus 로고
    • Two polypy-rimidine tracts in the nitric oxide synthase 2 gene: Similar regulatory sequences with different properties
    • Motallebipour M, Rada-Iglesias A, Westin G, Wadelius C. Two polypy-rimidine tracts in the nitric oxide synthase 2 gene: similar regulatory sequences with different properties. Mol Biol Rep. 2010;37:2021-2030.
    • (2010) Mol Biol Rep. , vol.37 , pp. 2021-2030
    • Motallebipour, M.1    Rada-Iglesias, A.2    Westin, G.3    Wadelius, C.4
  • 56
    • 50649091392 scopus 로고    scopus 로고
    • JT, Ghosh S, Kim J, Fushimi K, Wu JY, Stack MS, Huang S. Polypyrimidine tract-binding protein (PTB) differentially affects malignancy in a cell line-dependent manner
    • Norton
    • Wang C, Norton JT, Ghosh S, Kim J, Fushimi K, Wu JY, Stack MS, Huang S. Polypyrimidine tract-binding protein (PTB) differentially affects malignancy in a cell line-dependent manner. J Biol Chem. 2008;283:20277-20287.
    • (2008) J Biol Chem. , vol.283 , pp. 20277-20287
    • Wang, C.1
  • 57
    • 34547489950 scopus 로고    scopus 로고
    • Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro
    • He X, Pool M, Darcy KM, Lim SB, Auersperg N, Coon JS, Beck WT. Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro. Oncogene. 2007;26:4961-4968.
    • (2007) Oncogene. , vol.26 , pp. 4961-4968
    • He, X.1    Pool, M.2    Darcy, K.M.3    Lim, S.B.4    Auersperg, N.5    Coon, J.S.6    Beck, W.T.7
  • 58
    • 77950676582 scopus 로고    scopus 로고
    • P27kip1 controls cell morphology and motility by regulating microtubule-dependent lipid raft recycling
    • Belletti B, Pellizzari I, Berton S, et al. p27kip1 controls cell morphology and motility by regulating microtubule-dependent lipid raft recycling. Mol Cell Biol. 2010;30:2229-2240.
    • (2010) Mol Cell Biol. , vol.30 , pp. 2229-2240
    • Belletti, B.1    Pellizzari, I.2    Berton, S.3
  • 59
    • 84880699835 scopus 로고    scopus 로고
    • NOTCH1 functions as an oncogene by regulating the PTEN/PI3K/AKT pathway in clear cell renal cell carcinoma
    • Liu S, Ma X, Ai Q, Huang Q, Shi T, Zhu M, Wang B, Zhang X. NOTCH1 functions as an oncogene by regulating the PTEN/PI3K/AKT pathway in clear cell renal cell carcinoma. Urol Oncol. 2013;31:938-948.
    • (2013) Urol Oncol. , vol.31 , pp. 938-948
    • Liu, S.1    Ma, X.2    Ai, Q.3    Huang, Q.4    Shi, T.5    Zhu, M.6    Wang, B.7    Zhang, X.8
  • 60
    • 34948908663 scopus 로고    scopus 로고
    • Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
    • Palomero T, Sulis ML, Cortina M, et al. Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia. Nat Med. 2007;13:1203-1210.
    • (2007) Nat Med. , vol.13 , pp. 1203-1210
    • Palomero, T.1    Sulis, M.L.2    Cortina, M.3
  • 61
    • 67749093259 scopus 로고    scopus 로고
    • Crosstalk of Notch with p53 and p63 in cancer growth control
    • Dotto GP. Crosstalk of Notch with p53 and p63 in cancer growth control. Nat Rev Cancer. 2009;9:587-595.
    • (2009) Nat Rev Cancer. , vol.9 , pp. 587-595
    • Dotto, G.P.1
  • 62
  • 63
    • 79955460636 scopus 로고    scopus 로고
    • Notch signalling in solid tumours: A little bit of everything but not all the time
    • Ranganathan P, Weaver KL, Capobianco AJ. Notch signalling in solid tumours: a little bit of everything but not all the time. Nat Rev Cancer. 2011;11:338-351.
    • (2011) Nat Rev Cancer. , vol.11 , pp. 338-351
    • Ranganathan, P.1    Weaver, K.L.2    Capobianco, A.J.3
  • 64
    • 33846621883 scopus 로고    scopus 로고
    • CBF-1 (RBP-J kappa) binds to the PTEN promoter and regulates PTEN gene expression
    • Whelan JT, Forbes SL, Bertrand FE. CBF-1 (RBP-J kappa) binds to the PTEN promoter and regulates PTEN gene expression. Cell Cycle. 2007;6:80-84.
    • (2007) Cell Cycle. , vol.6 , pp. 80-84
    • Whelan, J.T.1    Forbes, S.L.2    Bertrand, F.E.3
  • 66
    • 34047218122 scopus 로고    scopus 로고
    • HDAC inhibitors as anti-infammatory agents
    • Adcock IM. HDAC inhibitors as anti-infammatory agents. Br J Pharmacol. 2007;150:829-831.
    • (2007) Br J Pharmacol. , vol.150 , pp. 829-831
    • Adcock, I.M.1
  • 67
    • 76349122643 scopus 로고    scopus 로고
    • Protein acetylation in the cardiorenal axis: The promise of histone deacetylase inhibitors
    • Bush EW, McKinsey TA. Protein acetylation in the cardiorenal axis: the promise of histone deacetylase inhibitors. Circ Res. 2010;106:272-284.
    • (2010) Circ Res. , vol.106 , pp. 272-284
    • Bush, E.W.1    McKinsey, T.A.2
  • 69
    • 68849105560 scopus 로고    scopus 로고
    • Expression and function of histone deacetylases in rheumatoid arthritis synovial fbroblasts
    • Horiuchi M, Morinobu A, Chin T, Sakai Y, Kurosaka M, Kumagai S. Expression and function of histone deacetylases in rheumatoid arthritis synovial fbroblasts. J Rheumatol. 2009;36:1580-1589.
    • (2009) J Rheumatol. , vol.36 , pp. 1580-1589
    • Horiuchi, M.1    Morinobu, A.2    Chin, T.3    Sakai, Y.4    Kurosaka, M.5    Kumagai, S.6
  • 70
    • 84863231352 scopus 로고    scopus 로고
    • Selective class i histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism
    • Cavasin MA, Demos-Davies K, Horn TR, et al. Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism. Circ Res. 2012;110:739-748.
    • (2012) Circ Res. , vol.110 , pp. 739-748
    • Cavasin, M.A.1    Demos-Davies, K.2    Horn, T.R.3
  • 71
    • 84885421895 scopus 로고    scopus 로고
    • Histone deacetylases inhibitor trichostatin A increases the expression of Dleu2/miR-15a/16-1 via HDAC3 in non-small cell lung cancer
    • Chen CQ, Chen CS, Chen JJ, Zhou LP, Xu HL, Jin WW, Wu JB, Gao SM. Histone deacetylases inhibitor trichostatin A increases the expression of Dleu2/miR-15a/16-1 via HDAC3 in non-small cell lung cancer. Mol Cell Biochem. 2013;383:137-148.
    • (2013) Mol Cell Biochem. , vol.383 , pp. 137-148
    • Chen, C.Q.1    Chen, C.S.2    Chen, J.J.3    Zhou, L.P.4    Xu, H.L.5    Jin, W.W.6    Wu, J.B.7    Gao, S.M.8
  • 73
    • 60949102817 scopus 로고    scopus 로고
    • Hypoxia inducible factor-2alpha: A critical mediator of aggressive tumor phenotypes
    • Qing G, Simon MC. Hypoxia inducible factor-2alpha: a critical mediator of aggressive tumor phenotypes. Curr Opin Genet Dev. 2009;19:60-66.
    • (2009) Curr Opin Genet Dev. , vol.19 , pp. 60-66
    • Qing, G.1    Simon, M.C.2
  • 74
    • 84883203483 scopus 로고    scopus 로고
    • Differential regulation of pulmonary vascular cell growth by hypoxia-inducible transcription factor-1alpha and hypoxia-inducible transcription factor-2alpha
    • Ahmad A, Ahmad S, Malcolm KC, Miller SM, Hendry-Hofer T, Schaack JB, White CW. Differential regulation of pulmonary vascular cell growth by hypoxia-inducible transcription factor-1alpha and hypoxia-inducible transcription factor-2alpha. Am J Respir Cell Mol Biol. 2013;49:78-85.
    • (2013) Am J Respir Cell Mol Biol. , vol.49 , pp. 78-85
    • Ahmad, A.1    Ahmad, S.2    Malcolm, K.C.3    Miller, S.M.4    Hendry-Hofer, T.5    Schaack, J.B.6    White, C.W.7
  • 75
    • 34047156190 scopus 로고    scopus 로고
    • HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity
    • Gordan JD, Bertout JA, Hu CJ, Diehl JA, Simon MC. HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity. Cancer Cell. 2007;11:335-347.
    • (2007) Cancer Cell. , vol.11 , pp. 335-347
    • Gordan, J.D.1    Bertout, J.A.2    Hu, C.J.3    Diehl, J.A.4    Simon, M.C.5
  • 76
    • 72849111523 scopus 로고    scopus 로고
    • RNA-binding proteins implicated in the hypoxic response
    • Masuda K, Abdelmohsen K, Gorospe M. RNA-binding proteins implicated in the hypoxic response. J Cell Mol Med. 2009;13:2759-2769.
    • (2009) J Cell Mol Med. , vol.13 , pp. 2759-2769
    • Masuda, K.1    Abdelmohsen, K.2    Gorospe, M.3
  • 77
    • 29244458635 scopus 로고    scopus 로고
    • The polypy-rimidine tract-binding protein stimulates HIF-1alpha IRES-mediated translation during hypoxia
    • Schepens B, Tinton SA, Bruynooghe Y, Beyaert R, Cornelis S. The polypy-rimidine tract-binding protein stimulates HIF-1alpha IRES-mediated translation during hypoxia. Nucleic Acids Res. 2005;33:6884-6894.
    • (2005) Nucleic Acids Res. , vol.33 , pp. 6884-6894
    • Schepens, B.1    Tinton, S.A.2    Bruynooghe, Y.3    Beyaert, R.4    Cornelis, S.5
  • 78
    • 84879298794 scopus 로고    scopus 로고
    • Scleroderma pathogenesis: A pivotal role for fbroblasts as effector cells
    • Gilbane AJ, Denton CP, Holmes AM. Scleroderma pathogenesis: a pivotal role for fbroblasts as effector cells. Arthritis Res Ther. 2013;15:215.
    • (2013) Arthritis Res Ther. , vol.15 , pp. 215
    • Gilbane, A.J.1    Denton, C.P.2    Holmes, A.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.